[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Maisonneuve-Rosemont Hospital\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":71},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,44],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":5},"100456007","single-pre-operative-radiation-therapy---with-delayed-or-no-surgery-sport-dns-100456007",false,"NCT05217966","Single Pre-Operative Radiation Therapy - With Delayed or No Surgery (SPORT-DNS)","Single Pre-Operative Radiation Therapy - With Delayed or No Surgery (SPORT-DNS) for Low Risk Breast Cancer: A Phase II Study","SPORT-DNS","Inclusion Criteria:\n\n1. Female aged 50 years or older.\n2. Postmenopausal status (Defined as: age 60 OR bilateral ovariectomy OR amenorrhea \\> 12 months prior to breast cancer diagnosis without using oral contraceptives\u002Fhormone replacement therapy) (65).\n3. World Health Organization (WHO) performance status 0-2.\n4. Invasive ductal carcinoma proven by biopsy done ≤ 12 weeks from treatment start.\n5. Unifocal disease on preoperative staging ultrasound or MRI done ≤ 12 weeks from treatment start.\n6. Tumors less than or equal to 2cm clinically on physical exam, as well as on breast ultrasound.\n7. No clinical evidence of nodal disease (i.e. cN0), on physical examination done ≤ 12 weeks from treatment start, as well as on breast ultrasound.\n8. Estrogen receptor status (ER) positive on biopsy ≥ 80%.\n9. Progesterone receptor status (PR) positive on biopsy ≥ 20%.\n10. Her2 negative on biopsy.\n11. No lymphovascular invasion on biopsy.\n12. Low Oncotype DX recurrence score performed on biopsy specimen (RS ≤18).\n13. Planned surgery is a partial mastectomy with sentinel lymph node biopsy.\n\nExclusion Criteria:\n\n1. Age less than 50 years.\n2. Premenopausal or uncertain menopausal status.\n3. A known deleterious mutation in BRCA 1 and\u002For BRCA 2.\n4. Clinical tumor size \\> 2.0 cm in greatest diameter on staging ultrasound.\n5. Tumor histology limited to lobular carcinoma only.\n6. Clinically positive axillary nodes (cN+).\n7. Lymphovascular invasion on biopsy.\n8. Pure ductal or lobular carcinoma in situ on biopsy.\n9. Extensive intraductal component on biopsy.\n10. Neoadjuvant hormonal manipulation or chemotherapy.\n11. Prior non basal cell or squamous cell skin cancers within 5 years.\n12. More than one primary tumor in different quadrants of the same breast.\n13. Diffuse microcalcifications on mammography.\n14. Paget's disease of the nipple.\n15. Previous irradiation to the ipsilateral breast.\n16. Presence of an ipsilateral breast implant or pacemaker.\n17. Serious non-malignant disease (e.g. cardiovascular, pulmonary, systemic lupus erythematosus (SLE), scleroderma) which would preclude definitive radiation treatment.\n18. Estrogen receptor status (ER) not known.\n19. Currently pregnant or lactating.\n20. Psychiatric or addictive disorders which would preclude obtaining informed consent or adherence to protocol.\n21. Geographic inaccessibility for follow-up.\n22. Lack of preoperative staging with breast and axillary ultrasound.\n23. Inability to adequately plan the patient for the experimental technique.\n24. Prior breast cancer.","FEMALE","50 Years",{"count":20,"type":21},80,"ESTIMATED","INTERVENTIONAL",[24],"NA","Eligible women will receive neoadjuvant single fraction radiotherapy followed by surgery performed after one year",[27],"Breast Cancer",[29,30,31],"ablative radiotherapy","preoperative radiotherapy","neoadjuvant radiotherapy","RECRUITING","2024-11-18",{"date":35,"type":36},"2024-11-19","ACTUAL",{"date":38,"type":36},"2021-10-08",{"date":40,"type":21},"2030-12-31",{"name":42,"class":43},"Maisonneuve-Rosemont Hospital","OTHER",{"id":45,"slug":46,"hasResults":11,"nctId":47,"briefTitle":48,"officialTitle":49,"acronym":50,"eligibilityCriteria":51,"healthyVolunteers":52,"sex":53,"minAge":4,"maxAge":4,"enrollmentInfo":54,"targetDuration":4,"studyType":22,"phases":56,"briefSummary":57,"conditions":58,"keywords":4,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":62,"lastUpdatePostDateStruct":63,"startDateStruct":65,"completionDateStruct":67,"leadSponsor":69,"locationsCount":70},"100557082","evaluation-of-a-perceptual-learning-module-on-spinal-ultrasound-among-residents-100557082","NCT06533488","Evaluation of a Perceptual Learning Module on Spinal Ultrasound Among Residents.","Evaluation of the Impact of a Perceptual Learning Module (PLM) on the Sonographic Identification of Spinal Structures by Novice Anesthesiology Residents. A Randomized Controlled Study","MAP-Rachis","Inclusion Criteria (participants) :\n\n* To be a first, second, third, or fourth-year resident in the anesthesiology program at the Université de Montréal.\n* Not having experience in spinal ultrasound (defined as not having performed more than 5 spinal ultrasounds, whether accompanied or not).\n* To be familiar with ultrasound.\n* Consenting to participate in the study.\n\nInclusion Criteria (experts) :\n\n\\- Having used spinal ultrasound in clinical practice or taught it within the last year.\n\nExclusion Criteria (participants) :\n\n* Refusal to consent\n* Not meeting the inclusion criteria.",true,"ALL",{"count":55,"type":21},20,[24],"This medical education research project aims to evaluate the impact of a directed perceptual learning module (PLM) on spinal sonoanatomy. Following a demographic questionnaire, participants will be exposed to a tutorial explaining the necessary theoretical foundations for the PLM as well as the functioning of the PLM interface. A pre-test involving selecting the best image from a video sequence depicting spinal sonoanatomy will be administered to all participants. Participants will then be randomized into two groups and exposed to video sequences in the same manner as during the pre-test, with immediate feedback in the intervention group and no feedback in the control group. The video sequences presented will be the same between the two groups. Finally, a post-test will be administered immediately and remotely after exposure to the PLM. The time window corresponding to the best image will be predefined by an expert and compared to the resident\\'s value. The difference in feedback exposure between the two groups will not be revealed to limit biases.",[59,60,61],"Spinal Anesthesia Skill","Ultrasound Imaging of Anatomical Structures","Medical Education","2024-07-29",{"date":64,"type":36},"2024-08-01",{"date":66,"type":36},"2024-03-26",{"date":68,"type":21},"2025-04",{"name":42,"class":43},1,""]