[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Malmö University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":300},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,11,0,[8,41,66,100,124,143,170,197,227,253,274],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":4},"100622930","families-experiencing-cancer---support-to-prevent-cancer-related-illness-100622930",false,"NCT07390019","Families Experiencing Cancer - Support to Prevent Cancer-related Illness","FamCASP","Inclusion Criteria:\n\nParticipants are adult (≥18years) family members to patients diagnosed with CRC. Inclusion criteria are the ability to read and understand Swedish and having access to a computer, tablet or mobile phone to access the digital screening tool as well as the study information.\n\nExclusion Criteria:\n\n\\-","ALL","18 Years",{"count":19,"type":20},800,"ESTIMATED","INTERVENTIONAL",[23],"NA","In this planned project, we aim to evaluate the FamCASP model and the digital screening tool SCa-N as an intervention within routine cancer care. An expected outcome of FamCASP is an increase in family health as expressed in lower levels of psychological distress, improved coping strategies and family climate and a decrease in unmet needs as measured by family members' self-reports as well as their descriptions during interviews. Hence, the specific aims are to:\n\nI. Describe differences in psychological distress, coping strategies, family climate and unmet needs between baseline and follow-up in family members receiving support according to the FamCASP model in outpatient cancer clinics and to explore whether or not there are differences between family members receiving support and those who do not receive support.\n\nII. Describe family members' experiences of receiving support according to the FamCASP model.\n\nIII. Describe family members' experiences of interacting with the digital tool.",[26,27,28],"Cancer","Family Members","Support, Family","NOT_YET_RECRUITING","2026-01-29",{"date":32,"type":33},"2026-02-05","ACTUAL",{"date":35,"type":20},"2026-02-02",{"date":37,"type":20},"2032-12-30",{"name":39,"class":40},"Malmö University","OTHER",{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":4,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":48,"minAge":17,"maxAge":49,"enrollmentInfo":50,"targetDuration":4,"studyType":21,"phases":52,"briefSummary":53,"conditions":54,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":58,"lastUpdatePostDateStruct":59,"startDateStruct":61,"completionDateStruct":62,"leadSponsor":64,"locationsCount":65},"100619460","burning-mouth-syndrome-effects-of-occlusal-splint-therapy-100619460","NCT07344909","Burning Mouth Syndrome: Effects of Occlusal Splint Therapy","The Effects of Essix Splint Therapy on Burning Mouth Syndrome. A Prospective N-of-1 Study.","Inclusion Criteria:\n\n* patients with oral mucosal pain from participants in the previous BMS validation study.\n* greater than 30% pain relief during prior use of an Essix appliance.\n* chronic intraoral pain lasting more than 3 months.\n* age between 18 and 80 years.\n\nExclusion Criteria:\n\n* fibromyalgia\n* ongoing dental treatment","FEMALE","80 Years",{"count":51,"type":20},12,[23],"Burning Mouth Syndrome (BMS) causes chronic oral pain and significantly affects quality of life. Effective treatments are limited and often provide only temporary relief.\n\nThis prospective N-of-1 study evaluates the effect of an intraoral Essix appliance on pain intensity and salivary secretion in patients with BMS.\n\nSaliva samples are collected and analysed for volume and composition.",[55,56,57],"Burning Mouth Syndrome","Orofacial Pain","Mouth Dryness","2026-01-08",{"date":60,"type":33},"2026-01-15",{"date":60,"type":20},{"date":63,"type":20},"2027-11-01",{"name":39,"class":40},1,{"id":67,"slug":68,"hasResults":11,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":72,"eligibilityCriteria":73,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":74,"targetDuration":4,"studyType":21,"phases":76,"briefSummary":77,"conditions":78,"keywords":81,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":92,"lastUpdatePostDateStruct":93,"startDateStruct":95,"completionDateStruct":97,"leadSponsor":99,"locationsCount":4},"100600254","epropp---ehealth-for-preventing-and-reducing-orofacial-pain-in-the-population-100600254","NCT07095101","ePROPP - eHealth for Preventing and Reducing Orofacial Pain in the Population","Effect and Cost-effectiveness of Smartphone-based Behavioural Intervention on Orofacial Pain","ePROPP","Inclusion criteria\n\n* Chronic orofacial pain, duration ≥3 months with a diagnosis of Myalgia according to the brief DC\u002FTMD.\n* Patients will be included even if they have one or more additional DC\u002FTMD diagnoses\n* Regular smartphone users\n* Understanding written and spoken Swedish\n* Age ≥ 18 years\n\nExclusion criteria\n\n* Other orofacial non-TMD pain conditions\n* Cognitive impairment.",{"count":75,"type":20},120,[23],"Pain in the orofacial region has a 10% prevalence in the general population and health care providers are therefore expected to encounter these patients on a daily basis. Chronic orofacial pain often presents as jaw pain related to overload of the jaw muscles and temporomandibular joints. The aim of this study is to evaluate the effectiveness of a smartphone-based behavioural intervention (Ecological Momentary Intervention, EMI) grounded in Cognitive Behavioural Therapy (CBT), compared to standard treatment with an occlusal splint and a waiting list control group.",[79,80],"Temporomandibular Joint Disorder","Temporomandibular Disorders (TMDs)",[80,82,83,84,85,86,87,88,89,90,91],"Myalgia","Facial Pain","Behavior therapy","Telemedicine","Digital health","Occlusal splints","Cost-effectiveness analysis","Bruxism","Mobile applications","Cognitive Behavioral Therapy","2025-07-31",{"date":94,"type":33},"2025-08-05",{"date":96,"type":20},"2025-08-22",{"date":98,"type":20},"2028-12-31",{"name":39,"class":40},{"id":101,"slug":102,"hasResults":11,"nctId":103,"briefTitle":104,"officialTitle":105,"acronym":4,"eligibilityCriteria":106,"healthyVolunteers":11,"sex":16,"minAge":107,"maxAge":108,"enrollmentInfo":109,"targetDuration":4,"studyType":111,"phases":4,"briefSummary":112,"conditions":113,"keywords":4,"overallStatus":115,"whyStopped":4,"lastUpdateSubmitDate":116,"lastUpdatePostDateStruct":117,"startDateStruct":119,"completionDateStruct":121,"leadSponsor":123,"locationsCount":65},"100464001","validation-of-faces-thermometer-scale-fts-100464001","NCT05322018","Validation of Faces Thermometer Scale (FTS)","Validation of a Novel Digital Pain Measure, Faces Thermometer Scale (FTS) in a Swedish Dental Context","Inclusion Criteria:\n\n* 8 to 17 years of age, undergoing dental procedures and\u002For examinations\n\nExclusion Criteria:\n\n* cannot understand Swedish nor instructions on how to use the pain measure tools","8 Years","17 Years",{"count":110,"type":20},150,"OBSERVATIONAL","The aim of this study is to evaluate validity and reliability of a novel digital pain measure tool, the Faces Thermometer Scale (FTS). Pain is commonly reported by children and adolescents undergoing dental treatment. Pain is also a strongly contributing factor in the development of Dental Fear and Anxiety (DFA). Professionals often underestimate the pain perceived by their patients. Self-report tools are seldom used to measure pain in a clinical setting, denying child patients the possibility to communicate their pain experiences.\n\nThe aim of this study is to evaluate validity and reliability of a digital self-report pain measure tool, the Faces Thermometer Scale (FTS). Children and adolescents (N=150) aged 8 to 17 years visiting a dental clinic will be asked to score their pain using three different self-report pain tools; FTS, Faces Pain Scale-Revised (FPS-R) and Color Analog Scale (CAS). The validity and reliability of FPS-R and CAS is long established and will therefore be used to evaluate the psychometric properties of FTS.",[114],"Pain","RECRUITING","2025-05-14",{"date":118,"type":33},"2025-05-18",{"date":120,"type":33},"2022-05-01",{"date":122,"type":20},"2025-12-31",{"name":39,"class":40},{"id":125,"slug":126,"hasResults":11,"nctId":127,"briefTitle":128,"officialTitle":129,"acronym":4,"eligibilityCriteria":130,"healthyVolunteers":131,"sex":16,"minAge":17,"maxAge":132,"enrollmentInfo":133,"targetDuration":4,"studyType":111,"phases":4,"briefSummary":135,"conditions":136,"keywords":4,"overallStatus":115,"whyStopped":4,"lastUpdateSubmitDate":116,"lastUpdatePostDateStruct":137,"startDateStruct":138,"completionDateStruct":140,"leadSponsor":142,"locationsCount":65},"100411930","pain-in-pediatric-dentistry---a-grounded-theory-study-on-the-experiences-of-dental-professionals-and-students-100411930","NCT04643951","Pain in Pediatric Dentistry - a Grounded Theory Study on the Experiences of Dental Professionals and Students","Pain in Pediatric Dentistry - a Grounded Theory Study on the Experiences of Dental","Inclusion Criteria:\n\n* Dental students in their 4th or 5th year of training\n* Dental professionals working with child patients on a regular basis\n\nExclusion Criteria:\n\n• Do not understand Swedish language",true,"65 Years",{"count":134,"type":20},35,"This is a qualitative interview study, using Grounded Theory. The aim is to deepen our knowledge about how the dental team (dentists, dental hygienists, and dental assistants) and dental students perceive child patients' pain and how they perceive they are equipped to prevent and deal with child patients' pain and the child's response to pain during and after dental treatment.",[114],{"date":118,"type":33},{"date":139,"type":33},"2020-12-01",{"date":141,"type":20},"2026-12-30",{"name":39,"class":40},{"id":144,"slug":145,"hasResults":11,"nctId":146,"briefTitle":147,"officialTitle":148,"acronym":149,"eligibilityCriteria":150,"healthyVolunteers":11,"sex":16,"minAge":151,"maxAge":152,"enrollmentInfo":153,"targetDuration":4,"studyType":21,"phases":155,"briefSummary":156,"conditions":157,"keywords":159,"overallStatus":115,"whyStopped":4,"lastUpdateSubmitDate":161,"lastUpdatePostDateStruct":162,"startDateStruct":164,"completionDateStruct":166,"leadSponsor":168,"locationsCount":169},"100580110","comparing-a-novel-closed-exposure-technique-to-a-conventional-method-for-palatally-impacted-maxillary-canines-100580110","NCT06833034","Comparing a Novel Closed Exposure Technique to a Conventional Method for Palatally Impacted Maxillary Canines","To Compare the Effectiveness of a Novel Closed Exposure Technique With Removal of Bone Tissue and a Conventional Technique During Treatment of Palatally Impacted Maxillary Canines by Closed Surgical Exposure and Fixed Orthodontic Appliance","PDC","Inclusion Criteria:\n\n• Patients with palatally impacted maxillary canine on one side, in sector 2-4 and with angle \\\u003C45º are included.\n\nExclusion Criteria:\n\n* Patients with clefts or syndromes\n* Patients with earlier orthodontic treatment\n* Patients with canines with angle \\>45º (fig.1)\n* Patients with canines with impacted canines in sectors 1 or 2","10 Months","18 Months",{"count":154,"type":20},66,[23],"A multi-center Randomized Clinical Trial, (RCT) on treatment effectiveness of two different closed surgical exposure techniques, one including additional bone removal and a second conventional without removal of additional bone, during treatment of palatally impacted maxillary canines.\n\nA comparison between the two methods regarding the anchorage situation for the incisors will be performed as well.\n\nIntroduction Surgical exposure of impacted maxillary canines together with orthodontic treatment has long been advocated. Closed exposure with placement of an auxiliary attachment with a chain, followed by traction of the canine with orthodontic forces is commonly clinical used to avoid complications with the open procedure (Kokich 2004). Both open and closed methods and orthodontic treatment are one of the most time-consuming orthodontic treatments. Therefore, it is valuable to try to find methods which can reduce the total treatment time and make the treatments as comfortable as possible for the patient.\n\nTo reduce the treatment time, study I investigates a novel strategy for traction of the canine. Another strategy to reduce the treatment time might be to facilitate the movement of the canine by additional bone removal in the eruption direction out to the alveolar crest. This has been used of a few orthodontists in one clinic for some years. No negative side-effects have been seen. There are, however, no studies for comparison of the two techniques.\n\nAim The primary aims of this Randomized Clinical Trial (RCT) is to evaluate the treatment effectiveness of two different surgical closed exposure techniques of palatally impacted canines before the orthodontic treatment; a) with removal of bone in traction direction and b) without removal of bone in traction direction and to evaluate the anchorage situations.\n\nOutcome variables The outcome variables will be: 1) Treatment time for the canine to be exposed in the oral cavity; 2) Treatment time for the canine to be in the dental arch and 3) Treatment time for the canine to have reached the right position in the dental arch.\n\nSubjects Sixty-six patients between 10-18- years, will be recruited to the study. Patients with palatally impacted maxillary canines are consecutively recruited at three orthodontic clinics in Lund, Karlshamn and Ängelholm.",[158],"Impacted Canines",[160],"impacted maxillary canines","2025-05-09",{"date":163,"type":33},"2025-05-11",{"date":165,"type":33},"2025-03-07",{"date":167,"type":20},"2026-07-10",{"name":39,"class":40},2,{"id":171,"slug":172,"hasResults":11,"nctId":173,"briefTitle":174,"officialTitle":175,"acronym":4,"eligibilityCriteria":176,"healthyVolunteers":131,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":177,"targetDuration":4,"studyType":21,"phases":179,"briefSummary":180,"conditions":181,"keywords":186,"overallStatus":115,"whyStopped":4,"lastUpdateSubmitDate":191,"lastUpdatePostDateStruct":192,"startDateStruct":193,"completionDateStruct":195,"leadSponsor":196,"locationsCount":65},"100462990","prosenior-prevention-of-pressure-ulcers-malnutrition-poor-oral-health-and-falls-among-older-persons-receiving-municipal-health-care-and-are-registered-in-the-quality-registry-senior-alert-100462990","NCT05308862","PROSENIOR. Prevention of Pressure Ulcers, Malnutrition, Poor Oral Health and Falls Among Older Persons Receiving Municipal Health Care and Are Registered in the Quality Registry Senior Alert","Prevention of Pressure Ulcers, Malnutrition, Poor Oral Health and Falls Among Older Persons Receiving Municipal Health Care and Are Registered in the Quality Registry Senior Alert","Inclusion Criteria:\n\n* Nursing homes registering in Senior Alert, which is a national quality registry\n\nExclusion Criteria:\n\n* not meetin inclusion criteria",{"count":178,"type":20},330,[23],"Inclusion criteria for study I and II is nurse aides, registered nurses and managers working in nursing homes who register in Senior Alert. To develop an intervention aiming to reduce the risk of pressure ulcers, malnutrition, poor oral health and falls among older persons in nursing homes, workshops will be conducted in collaboration with nurse aides, registered nurses and managers (study I). Cluster randomization is going to take place via a computerized program prior to the workshops meaning that only those nurse aides, registered nurses and managers working in nursing homes allocated to the intervention group are going to develop an intervention together with the research group and then test it (study II). The remaining nurse aides, registered nurses and managers working in nursing homes in the control group continue with regular care.",[182,183,184,185],"Fall","Pressure Ulcer","Malnutrition","Oral Health",[187,188,189,190],"Prevention","Older people","Nursing care","Complex intervention","2025-05-07",{"date":161,"type":33},{"date":194,"type":33},"2022-01-19",{"date":122,"type":20},{"name":39,"class":40},{"id":198,"slug":199,"hasResults":11,"nctId":200,"briefTitle":201,"officialTitle":202,"acronym":4,"eligibilityCriteria":203,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":204,"targetDuration":4,"studyType":21,"phases":206,"briefSummary":207,"conditions":208,"keywords":212,"overallStatus":115,"whyStopped":4,"lastUpdateSubmitDate":218,"lastUpdatePostDateStruct":219,"startDateStruct":221,"completionDateStruct":223,"leadSponsor":225,"locationsCount":226},"100408974","one-vs-two-visits-root-canal-treatments-in-infected-teeth-100408974","NCT04605445","One Vs Two Visits Root Canal Treatments in Infected Teeth","One Vs Two Visits Endodontics - a Prospective Randomized Multicenter Study in General Dental Practice","Inclusion Criteria:\n\n* Patient older than 17 years.\n* Permanent tooth excluding third molars.\n* Necrotic tooth with\u002Fwithout clinical and\u002For radiological signs of apical (juxta radicular) periodontitis (non-bleeding pulp in the canal orifice. In case of a multi rooted tooth, a non-bleeding pulp in at least one root canal orifice) where orthograde endodontic treatment is planned.\n\nExclusion Criteria:\n\n* Patients with severe general disease and\u002F or where endodontic treatment requires special consideration for health reasons (eg radiation-treated jaw bone in the area or increased susceptibility to infection).\n* Systemic involvement (fever).\n* Swelling (extra- and\u002For intra oral).\n* Previously root canal treated tooth (instrumented and\u002For rotfilled).\n* Confirmed or strong suspicion of transverse or longitudinal root fracture.\n* Trauma to the tooth (\\\u003C6 month).\n* Marginal bone loss \\>1\u002F3 of the root lenght.\n* Root resorption.\n* Non restorable tooth.\n* Endodontic treatment is not considered feasible because rubberdam cannot be used on the tooth.\n* Follow-up at the clinic of the treatment after\\> 1 year is considered not feasible.",{"count":205,"type":20},1000,[23],"The primary aim of the study is to compare the outcome of one vs two visits endodontics (root canal treatments) performed in general dental practice of infected (necrotic) teeth, one and four years after treatment. Secondary aims are to compare the root filling quality and the frequency of complications for both treatment modalities.\n\nA pilot study will identify the shortcomings of the protocol, which will be revised accordingly.\n\nA multi-center study in several clinics from five counties throughout Sweden is planned. Consecutive eligible patients (see inclusion and exclusion criteria) with one tooth each will be included.\n\nThe study sample size calculation was based on a judgement that a minimal worthwhile effect of less than 10% was not clinically relevant. The presumption was that successful outcomes would be of 75% and 65% for the different treatment arms, respectively. Three hundred and fifty six patients per group are thus needed to detect that difference as statistical significant with a power of 80% and an alfa-error of 5%. To compensate for around 30% drop-outs a number of 1000 patients will be recruited.\n\nPatients will be randomly enrolled in two arms: one in which the endodontic treatment (root canal treatment) is performed in one visit, and in the other arm in two visits. The allocation sequences for one vs multiple visit endodontics will be computer generated followed by a dark colored envelope concealed allocation.\n\nThe patients will be contacted by telephone 5-7 days post-operatively, and a control visit at the clinic will be scheduled one month post-operatively to assess complications related to the treatment.\n\nA clinical control will be performed at the clinic one and four years after treatment. Intra-oral radiographs will be taken. The radiographs will be examined by two blinded and independent observers. A successful outcome is defined by clinical and radiographic normalcy.\n\nThe statistical methods selected to analyse the primary outcome will be the Chi square test of 2x2 tables, or Fisher´s exact test when proportions are small and the expected value \\\u003C5. The calculations will be two-tailed. Results will be considered statistically significant at p\\\u003C0.05.",[209,114,210,211],"Apical Periodontitis","Tooth Loss","Dental Pulp Necrosis",[213,214,215,216,217],"Endodontics","General Dental Practice","Single Visit","Multiple Visits","Infection Barrier","2024-12-11",{"date":220,"type":33},"2024-12-16",{"date":222,"type":33},"2020-11-18",{"date":224,"type":20},"2031-12",{"name":39,"class":40},7,{"id":228,"slug":229,"hasResults":11,"nctId":230,"briefTitle":231,"officialTitle":232,"acronym":4,"eligibilityCriteria":233,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":234,"targetDuration":4,"studyType":21,"phases":236,"briefSummary":238,"conditions":239,"keywords":242,"overallStatus":115,"whyStopped":4,"lastUpdateSubmitDate":246,"lastUpdatePostDateStruct":247,"startDateStruct":248,"completionDateStruct":250,"leadSponsor":252,"locationsCount":65},"100548968","phase-4-treatment-effects-of-two-pharmaceutical-skin-care-creams-for-xerotic-feet-among-persons-with-diabetes-100548968","NCT06427889","Treatment Effects of Two Pharmaceutical Skin Care Creams for Xerotic Feet Among Persons with Diabetes","A Superiority Study Comparing Two Pharmaceutical Skin Care Creams Containing Different Humectants with a Non-humectant Containing Skin Care Cream for the Treatment of Xerotic Foot of Persons with Diabetes","Inclusion Criteria:\n\n* Persons above 18 years of age diagnosed with diabetes mellitus, both type I and II, with self-experienced dry skin.\n* Dry skin on both feet with a Xerosis Severity Scale (XSS) score between two to six. No more than one XSS score in difference between the subjects' feet.\n* Ability to understand sufficient Swedish language to complete the necessary forms and understand the procedure of the study.\n\nExclusion Criteria:\n\n* Known sensibility to any of the ingredients in the products.\n* Other diagnosed skin disease on the feet.\n* Active lesions on either foot.\n* Treatment with local medications, including topical moisturizers or keratolytic agents on the feet, within two weeks before the beginning of the study.\n* Potential study subjects judged unable to comply with treatment schedule and study specific information.\n* Female of childbearing potential that do not use effective medically accepted contraception.",{"count":235,"type":20},98,[237],"PHASE4","Introduction Diabetic foot-ulcers leads to decreased quality of life, risk of major amputation, and resource demanding health-care. To minimize the risk of developing foot-ulcers, persons with diabetes are given the advice to daily inspect their feet and to apply skincare formulations. However, commercially available skincare products have rarely been developed and evaluated for diabetes foot care specifically. The primary aim of this randomized controlled trial (RCT) is to evaluate the effects in reducing foot xerosis in persons with diabetes without foot-ulcers using two skincare creams containing different humectants (interventions) against a cream base non-humectant (comparator). Secondary outcomes are to evaluate differences on skin barrier integrity, low-molecular weight biomarkers and skin microbiota, microcirculation including transcutaneous oxygen pressure, degree of neuropathy, and HbA1c between intervention-comparator cream. Methods Two-armed double-blind RCT. With 80% power, two-tailed significance of 2.5% in each arm, 39 study persons is needed in each arm, total 78 persons, to be able to prove a reduction of at least one category in the Xerosis Severity Scale with the intervention creams compared to the comparator. In one arm, each participant will treat one foot with one of the intervention creams (Oviderm® or Canoderm®), while the opposite foot will be treated with the comparator cream (Decubal® lipid cream®), twice a day. If needed, participants are enrolled after a wash-out period of two weeks. The participants will undergo examinations at baseline, day 14 and day 28. Discussion This RCT evaluate the potential effects of humectants in skin creams against foot xerosis in persons with diabetes. The outcomes of this trial could have implications on treatment recommendations of foot care and for the prevention of foot ulcer.",[240,241],"Diabetes Mellitus","Skin and Connective Tissue Diseases",[240,243,244,245,187],"Dry Skin","Self Care","Dry Feet","2024-12-06",{"date":218,"type":33},{"date":249,"type":33},"2024-09-04",{"date":251,"type":20},"2026-08-07",{"name":39,"class":40},{"id":254,"slug":255,"hasResults":11,"nctId":256,"briefTitle":257,"officialTitle":257,"acronym":4,"eligibilityCriteria":258,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":259,"enrollmentInfo":260,"targetDuration":4,"studyType":111,"phases":4,"briefSummary":262,"conditions":263,"keywords":4,"overallStatus":115,"whyStopped":4,"lastUpdateSubmitDate":265,"lastUpdatePostDateStruct":266,"startDateStruct":268,"completionDateStruct":270,"leadSponsor":272,"locationsCount":273},"100465366","long-term-surgical-treatment-outcome-of-peri-implantitis-lesions-100465366","NCT05339789","Long-term Surgical Treatment Outcome of Peri-implantitis Lesions","Inclusion Criteria:\n\n* All patients being treated since 2014 and continuously being treated will be called in for regular check-ups after the surgical intervention and an examination for study purpose will be performed annually.\n\nExclusion criteria:\n\n\\- implant loss","130 Years",{"count":261,"type":20},650,"The surgical treatment outcome of patients that have been or are consecutively treated at the University of Malmö, at Blekinge hospital, and at the Dental Clinic of the Sigmund Freud University Vienna will be evaluated on an a regular base; specifically all patients treated since 2014 and those receiving treatment in the future, will be regularly assessed, max. once per year after the 1-year control from the surgical intervention for clinical and radiographic assessment of healing. Clinical peri-implant parameters (e.g., probing pocket depth) and peri-implant sulcus fluid (PISF) are collected, and a peri-apical radiographic examination is made. Further, from 200 patients treated in the future, the inflammatory peri-implant lesion will be collected and subjected to histological, microbiological, and molecular analysis. The removal of these lesions is a standard procedure and performed in all patients independent of study participation; i.e., the lesion has anyway to be removed during surgery and if the lesions are not stored, they would be thrown.",[264],"Peri-Implantitis","2024-02-15",{"date":267,"type":33},"2024-02-16",{"date":269,"type":33},"2020-08-30",{"date":271,"type":20},"2030-12-31",{"name":39,"class":40},3,{"id":275,"slug":276,"hasResults":11,"nctId":277,"briefTitle":278,"officialTitle":279,"acronym":4,"eligibilityCriteria":280,"healthyVolunteers":131,"sex":16,"minAge":281,"maxAge":282,"enrollmentInfo":283,"targetDuration":4,"studyType":111,"phases":4,"briefSummary":285,"conditions":286,"keywords":4,"overallStatus":115,"whyStopped":4,"lastUpdateSubmitDate":292,"lastUpdatePostDateStruct":293,"startDateStruct":295,"completionDateStruct":297,"leadSponsor":299,"locationsCount":273},"100442244","the-effect-of-malocclusions-on-oral-health-related-quality-of-life-100442244","NCT05038865","The Effect of Malocclusions on Oral Health Related Quality of Life","Oral Health Related Quality of Life - The Effect of Malocclusions, Gender, Socioeconomic Differences and Orthodontic Treatment Among Adolescents","Inclusion Criteria:\n\n* Adolescents 12-19 years of age with malocclusion (IOTN grade 4 and 5) referred to specialist orthodontic clinics\n* Adolescents 12-19 years of age without malocclusion (IOTN grad 1, 2 or 3) at general dentistry clinics\n\nExclusion Criteria:\n\n* Previous orthodontic treatment\n* Cleft lip and palate\n* ASA ≥ III\n* Intellectual and\u002For physical inability to answer questionnaires","12 Years","19 Years",{"count":284,"type":20},675,"Malocclusions in adolescents may affect oral health related quality of life. The study aims at;\n\n1. Evaluating two instruments measuring oral health related quality of life; \"Child Perceptions Questionnaire 11-14\" (CPQ 11-14) short form and \"Psychosocial Impact of Dental Aesthetics Questionnaire\" (PIDAQ).\n2. Comparing differences in oral health related quality of life in;\n\n   1. adolescents with different types of malocclusion and without malocclusions\n   2. individuals of different genders and socioeconomic status\n3. Longitudinally evaluating differences in oral health related quality of life;\n\n   1. before, during and after orthodontic treatment\n   2. in untreated individuals (without malocclusion) over time",[287,288,289,290,291],"Malocclusion","Quality of Life","Orthodontics","Adolescent","Socioeconomic Factors","2023-03-31",{"date":294,"type":33},"2023-04-04",{"date":296,"type":33},"2021-12-01",{"date":298,"type":20},"2027-12",{"name":39,"class":40},""]