[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Maria Elizabeth Rossi da Silva\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":49},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":30,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":5},"100589794","therapeutic-strategies-for-type-2-diabetes-based-on-lifestyle-changes-plant-based-diet-and-physical-exercise-100589794",false,"NCT06959043","Therapeutic Strategies for Type 2 Diabetes Based on Lifestyle Changes: Plant-based Diet and Physical Exercise","Inclusion Criteria:\n\n* Have a medical diagnosis of type 2 diabetes for a maximum of 5 years.\n* Be omnivorous; Have a Body Mass Index (BMI) ≥ 25 kg\u002Fm2 and \\\u003C 40 kg\u002Fm2;\n* Be between the ages of 45 and 70, both genders.\n* Women should be in the postmenopausal stage;\n* Use no more than three hypoglycemic medications in total;\n* Have the availability for a four-week consecutive hospitalization at CSVN.\n\nExclusion Criteria:\n\n* Be using insulin, anti-obesity medications, antibiotics, and\u002For probiotic supplements in the 2 months preceding data collection;\n* Use of alcohol or tobacco;\n* Have limited mobility and a previous diagnosis of cardiopulmonary diseases;\n* Report current or previous (within the past two months) diarrhea during screening;\n* Have liver or kidney failure and uncontrolled endocrine disorders (hypothyroidism, hypogonadism, and adrenal insufficiency);\n* Have eating disorders or have undergone bariatric surgery.","ALL","45 Years","70 Years",{"count":19,"type":20},60,"ESTIMATED","INTERVENTIONAL",[23],"NA","The study evaluates the impact of a strict vegetarian diet combined with regular physical exercise and the use of probiotics on metabolic, inflammatory, and epigenetic parameters in patients with type 2 diabetes. It aims to determine the influence of these interventions on gut microbiota, glycemic control, body composition, insulin resistance, and quality of life.",[26,27,28,29],"Type 2 Diabetes Mellitus (T2DM)","Insulin Resistance","Inflamation","Gut Microbiomes",[31,27,28,32,33,34,35,36],"Type 2 Diabetes Mellitus","Metabolic Syndrome","Physical Exercise","Gut Microbiome","Plant-based Diet","Lifestyle Interventions","RECRUITING","2025-05-13",{"date":40,"type":41},"2025-05-18","ACTUAL",{"date":43,"type":41},"2022-11-22",{"date":45,"type":20},"2026-12",{"name":47,"class":48},"Maria Elizabeth Rossi da Silva","OTHER",""]