[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Mark Schachman\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":49},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":5},"100575746","phase-4-endodontic-microsurgery-100575746",false,"NCT06776289","Endodontic Microsurgery","Endodontic Microsurgery With and Without Platelet-Rich Fibrin","EMS","Inclusion Criteria:\n\n* Maxillary or Mandibular Anterior teeth and premolars #4-13 and #20-29 with a history of failing RCT and a periapical radiolucency will be accepted\n\nExclusion Criteria:\n\n* Patients with vertical root fractures\n* Patients with non-restorable teeth\n* Patients with class 3 mobility\n* Pregnant\n* Smoker\n* Systematic disease contraindicating surgery","ALL","18 Years","90 Years",{"count":21,"type":22},20,"ESTIMATED","INTERVENTIONAL",[25],"PHASE4","Current literature on platelet rich fibrin (PRF) use in apicoectomies, also known as endodontic microsurgery, is sparse. PRF use in oral surgery or periodontal surgery has been more thoroughly researched. Whether it is able to reduce post-op pain or if it improves success rate in endodontic microsurgery is not well known. It is also not well known if it will be able to increase the rate of healing. This study will evaluate the success of endodontic microsurgery with and without PRF.",[28],"Apical Periodontitis",[30,31,32,33,34,35,36],"endo","endodontic","microsurgery","apicoectomy","apico","prf","platelet rich fibrin","NOT_YET_RECRUITING","2026-01-14",{"date":40,"type":41},"2026-01-16","ACTUAL",{"date":43,"type":22},"2026-03",{"date":45,"type":22},"2026-12-30",{"name":47,"class":48},"Mark Schachman","OTHER",""]