[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Marmara University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":702},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,77,0,25,[9,55,84,120,155,175,206,230,264,287,312,335,363,391,420,448,474,501,530,552,577,607,635,657,679],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":15,"acronym":4,"eligibilityCriteria":16,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":23,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":43,"lastUpdatePostDateStruct":44,"startDateStruct":47,"completionDateStruct":49,"leadSponsor":51,"locationsCount":54},"100054298","spsipb-versus-sapb-for-postoperative-analgesia-after-minimally-invasive-repair-of-pectus-excavatum-100054298",false,"NCT07697222","SPSIPB Versus SAPB for Postoperative Analgesia After Minimally Invasive Repair of Pectus Excavatum","Comparison of the Postoperative Analgesic Effects of Serratus Posterior Superior Intercostal Plane Block and Serratus Anterior Plane Block After Minimally Invasive Repair of Pectus Excavatum: A Prospective Observational Cohort Study","Inclusion Criteria:\n\n* Patients aged 15 to 25 years\n* Diagnosis of pectus excavatum\n* Scheduled to undergo minimally invasive repair of pectus excavatum under general anesthesia\n* Receipt of either bilateral serratus posterior superior intercostal plane block or bilateral serratus anterior plane block as part of routine perioperative analgesic care\n* Written informed consent obtained from the patient or, for patients younger than 18 years, from a legal guardian\n\nExclusion Criteria:\n\n* Refusal to participate in the study\n* Contraindication to regional anesthesia\n* Known allergy to local anesthetics or study analgesic medications\n* Chronic opioid use\n* Pre-existing chronic pain syndrome\n* Coagulopathy or use of anticoagulant therapy that contraindicates regional block application\n* Local infection at the block injection site\n* Neurological or psychiatric condition that may interfere with pain assessment\n* Incomplete perioperative or postoperative data\n* Conversion to another surgical technique or major intraoperative complication requiring a change in the routine analgesic protocol","ALL","15 Years","25 Years",{"count":21,"type":22},80,"ESTIMATED","7 Days","OBSERVATIONAL","This prospective observational cohort study will compare postoperative analgesic outcomes in patients undergoing minimally invasive repair of pectus excavatum. Participants will be grouped according to the regional analgesia technique applied as part of routine clinical care: serratus posterior superior intercostal plane block or serratus anterior plane block. The primary outcome will be total opioid consumption during the first 24 hours after surgery. Secondary outcomes will include postoperative pain scores, rescue analgesic requirement, opioid-related adverse effects, patient satisfaction, mobilization time, and length of hospital stay.",[27,28],"Pectus Excavatum","Chest Deformities",[30,31,32,33,34,35,36,37,38,39,40,41],"Pectus excavatum","Serratus Anterior Plane Block","Serratus Posterior Superior Intercostal Plane Block","Opioid-Free Anesthesia","Multimodal Analgesia","SAP Block","SPSIP Block","Postoperative Pain","Opioid-Related Adverse Effects","Opioid Consumption","Chest Deformity Surgery","Regional Anesthesia","RECRUITING","2026-07-06",{"date":45,"type":46},"2026-07-13","ACTUAL",{"date":48,"type":46},"2026-06-22",{"date":50,"type":22},"2027-06",{"name":52,"class":53},"Marmara University","OTHER",1,{"id":56,"slug":57,"hasResults":12,"nctId":58,"briefTitle":59,"officialTitle":59,"acronym":4,"eligibilityCriteria":60,"healthyVolunteers":12,"sex":17,"minAge":61,"maxAge":62,"enrollmentInfo":63,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":65,"conditions":66,"keywords":68,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":54},"100645245","the-effect-of-bottle-pep-exercise-on-expiratory-muscle-thickness-strength-and-balance-parameters-in-parkinsons-disease-patients-100645245","NCT07680725","The Effect of Bottle PEP Exercise on Expiratory Muscle Thickness, Strength, and Balance Parameters in Parkinson's Disease Patients","Inclusion Criteria:\n\n* Patients with a confirmed Parkinson's diagnosis who are being monitored\n* Those aged 18-75\n* Patients who are ambulatory\n\nExclusion Criteria:\n\n* Patients with acquired primary motor neuron disease (ischemic\u002Fhemorrhagic stroke, intracranial mass) and additional neurological diagnoses\n* Patients with hearing and cognitive impairments that prevent them from understanding or performing the exercise program\n* Presence of concomitant acute or chronic lung disease\n* History of thoracic or abdominal surgery\n* Severe heart disease\n* Active cancer\n* Mini-Mental State Examination (MMSE) score ≤ 24\n* Active smoking","18 Years","75 Years",{"count":64,"type":22},42,"Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by rigidity, tremor, postural instability, bradykinesia, and autonomic dysfunction. It is a common movement disorder worldwide. Motor impairments in PD patients are not limited to the muscles of the extremities; the neck, upper respiratory tract, and respiratory muscles are also affected. The resulting pulmonary dysfunction is one of the main factors contributing to morbidity and mortality in PD patients.\n\nRespiratory muscle exercise programs have been used to improve lung and swallowing function in patients with Parkinson's disease and other similar neurodegenerative disorders. Studies of inspiratory muscle exercise in Parkinson's patients have reported improvements in inspiratory muscle strength and endurance. Similarly, expiratory muscle exercise protocols have been shown to increase maximum expiratory pressure (MEP) and cough effectiveness. However, studies on expiratory muscle strengthening are lacking in the literature.\n\nPositive expiratory pressure (PEP) devices are used to clear airway secretions and feature a resistance that provides resistance during exhalation. This creates a positive pressure that stabilizes the airways during exhalation and prevents airway collapse. Although there are many PEP devices available on the market, the bottle-PEP, a therapist-made device, is used because it can be produced easily and at low cost. The bottle-PEP device consists of a bottle filled with at least 10 cm of water and a tube placed inside the bottle. Although information on strengthening expiratory muscles is traditionally found in the literature, there is no data in the literature on the effect of bottle-PEP use on expiratory muscle strength, especially in Parkinson's patients. A review of the literature shows that the effect of expiratory strengthening on balance has not been studied before.\n\nThis study aimed to demonstrate the effects of the bottle-PEP device, used in addition to expiratory muscle strengthening, on expiratory muscle thickness, strength, and balance.",[67],"Parkinson Disease (PD)",[69,70,71,72,73,74,75],"Parkinson","Parkinson disease","diaphragm thickness","inspiratory muscle","respiratory exercises","bottle-PEP","balance","2026-06-29",{"date":78,"type":46},"2026-07-02",{"date":80,"type":46},"2025-10-01",{"date":82,"type":22},"2026-11-01",{"name":52,"class":53},{"id":85,"slug":86,"hasResults":12,"nctId":87,"briefTitle":88,"officialTitle":89,"acronym":90,"eligibilityCriteria":91,"healthyVolunteers":92,"sex":17,"minAge":61,"maxAge":93,"enrollmentInfo":94,"targetDuration":4,"studyType":96,"phases":97,"briefSummary":99,"conditions":100,"keywords":103,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":113,"lastUpdatePostDateStruct":114,"startDateStruct":115,"completionDateStruct":117,"leadSponsor":119,"locationsCount":54},"100644795","local-dexamethasone-administration-in-symptomatic-irreversible-pulpitis-100644795","NCT07672873","Local Dexamethasone Administration in Symptomatic Irreversible Pulpitis","Comparison of the Effects of Submucosal and Intraligamentary Dexamethasone Administration on Anesthetic Success and Pain Control in Patients With Symptomatic Irreversible Pulpitis: A Randomized Clinical Trial","SIPDEX","Inclusion Criteria:\n\n* Patients aged 18 to 65 years.\n* ASA I or ASA II systemic health status.\n* Symptomatic irreversible pulpitis in a mandibular molar tooth.\n* Positive response to pulp sensibility tests.\n* Preoperative pain score greater than 54 mm on the Heft-Parker Visual Analog Scale (HP-VAS).\n* Ability to understand the study procedures and provide written informed consent.\n\nExclusion Criteria:\n\n* Pregnancy or lactation.\n* Allergy or contraindication to articaine, dexamethasone, or study-related medications.\n* Use of analgesics, anti-inflammatory drugs, or antibiotics within the previous 12 hours.\n* Presence of periapical radiolucency or diagnosis of pulpal necrosis.\n* Significant systemic disease (ASA III or higher).\n* Inability to complete pain assessment forms or follow study procedures.",true,"65 Years",{"count":95,"type":22},84,"INTERVENTIONAL",[98],"NA","Symptomatic irreversible pulpitis is associated with a high incidence of inadequate pulpal anesthesia during endodontic treatment, particularly in mandibular molar teeth. Failure to achieve profound anesthesia may result in increased intraoperative pain and patient discomfort. Corticosteroids have been suggested as adjunctive agents to improve pain control and reduce inflammatory responses; however, the influence of different local administration techniques on anesthetic success and postoperative pain remains unclear.\n\nThe aim of this randomized controlled clinical trial is to compare the effects of submucosal and intraligamentary dexamethasone administration on anesthetic success and pain control in patients with symptomatic irreversible pulpitis. A total of 84 participants requiring root canal treatment of mandibular first or second molars diagnosed with symptomatic irreversible pulpitis will be randomly allocated to one of three groups: (1) inferior alveolar nerve block (IANB) followed by submucosal saline injection (control group), (2) IANB followed by submucosal dexamethasone injection, and (3) IANB followed by intraligamentary dexamethasone injection.\n\nAll participants will receive standardized endodontic treatment under local anesthesia. The primary outcome measure is anesthetic success during access cavity preparation and pulp extirpation. Secondary outcome measures include postoperative pain intensity at 6, 12, 24, 48, and 72 hours, and postoperative analgesic consumption. The results of this study may provide evidence regarding the effectiveness of different local dexamethasone administration techniques and contribute to improved pain management strategies in endodontic practice.",[101,102],"Symptomatic Irreversible Pulpitis (SIP)","Dental Pain",[104,105,106,107,108,109,110,111,112],"Inferior alveolar nerve block","Dexamethasone","Submucosal injection","Intraligamentary injection","Symptomatic irreversible pulpitis","Endodontic treatment","Postoperative pain","Heft-Parker Visual Analog Scale","HP-VAS","2026-06-26",{"date":76,"type":46},{"date":116,"type":46},"2026-06-15",{"date":118,"type":22},"2026-12-18",{"name":52,"class":53},{"id":121,"slug":122,"hasResults":12,"nctId":123,"briefTitle":124,"officialTitle":125,"acronym":4,"eligibilityCriteria":126,"healthyVolunteers":12,"sex":17,"minAge":127,"maxAge":128,"enrollmentInfo":129,"targetDuration":4,"studyType":96,"phases":131,"briefSummary":132,"conditions":133,"keywords":140,"overallStatus":147,"whyStopped":4,"lastUpdateSubmitDate":148,"lastUpdatePostDateStruct":149,"startDateStruct":150,"completionDateStruct":152,"leadSponsor":154,"locationsCount":54},"100644489","think-find-solve-activities-for-insulin-self-management-in-type-1-diabetes-100644489","NCT07670572","Think-Find-Solve Activities for Insulin Self-Management in Type 1 Diabetes","The Effect of Think-Find-Solve Activities on Insulin Self-Management in Children With Type 1 Diabetes: A Randomized Controlled Trial","Inclusion Criteria:\n\n* For the child:\n\nDiagnosed with Type 1 diabetes Aged between 8 and 12 years Able to read and write Able to understand and speak Turkish Diagnosed with diabetes for at least one year Regularly attending routine three-month outpatient clinic follow-ups Having no other diseases or medical conditions aside from diabetes The child agrees to participate in the study\n\n-For the Parent: Being the mother or father of the child with Type 1 diabetes Being the primary caregiver responsible for the child Able to read and write Agrees to participate in the study\n\nExclusion Criteria:\n\nThe child uses an insulin pump\n\n\\-","8 Years","12 Years",{"count":130,"type":22},40,[98],"Children with type 1 diabetes require lifelong insulin therapy. However, improper management of insulin therapy may lead to serious, potentially life-threatening complications. The aim of this study is to examine the effect of an activity book developed for insulin therapy on insulin self-management among children with type 1 diabetes and their parents. The study is designed as a cluster randomized controlled experimental trial at the center level, including pre-test, 1- month, and 3-month follow-up measurements. The study will be initiated after obtaining ethical approval and institutional permissions. The sample will consist of children aged 8-12 years with type 1 diabetes and their parents. The study will be conducted in two different hospitals in Istanbul; using cluster randomization, one hospital will be assigned to the intervention group and the other to the control group. Prior to the main study, a pilot study will be conducted with 15 participants in each group, and the sample size will be calculated using G\\*Power based on the pilot data. Data will be collected using the \"Descriptive Information Form for Children with Diabetes\" and the \"Insulin Treatment Self-Management Scale (ITSMS) - Child (8-18 years) and Parent Forms.\" The \"Find-Solve-Learn Insulin Self-Management Activity Book\" will be applied to the children in the intervention group. The children will be monitored to complete the activity book at least twice a month for three months, and feedback will be obtained from their families regarding the process. The data collection process will include pre-test, 1-month, and 3-month follow-up measurements. The obtained data will be analyzed using appropriate statistical methods.",[134,135,136,137,138,139],"Type 1 Diabetes","Children","Activity","Insulin","Self Management","Parent",[141,142,143,144,145,146],"type 1 diabetes","children","activity","insulin","self management","parent","NOT_YET_RECRUITING","2026-06-25",{"date":113,"type":46},{"date":151,"type":22},"2026-07-15",{"date":153,"type":22},"2027-06-15",{"name":52,"class":53},{"id":156,"slug":157,"hasResults":12,"nctId":158,"briefTitle":159,"officialTitle":159,"acronym":4,"eligibilityCriteria":160,"healthyVolunteers":92,"sex":17,"minAge":61,"maxAge":62,"enrollmentInfo":161,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":163,"conditions":164,"keywords":166,"overallStatus":147,"whyStopped":4,"lastUpdateSubmitDate":48,"lastUpdatePostDateStruct":170,"startDateStruct":171,"completionDateStruct":172,"leadSponsor":174,"locationsCount":54},"100644571","ultrasonographic-evaluation-of-morphological-and-functional-characteristics-of-intercostal-muscles-in-stroke-patients-and-their-relationship-with-clinical-parameters-100644571","NCT07670585","Ultrasonographic Evaluation of Morphological and Functional Characteristics of Intercostal Muscles in Stroke Patients and Their Relationship With Clinical Parameters","Inclusion Criteria (Stroke Group):\n\n* Age between 18 and 75 years.\n* History of ischemic or hemorrhagic stroke.\n* Ability to understand and comply with study procedures.\n* Provision of written informed consent.\n\nExclusion Criteria (Stroke Group):\n\n* Presence of acute or chronic pulmonary disease.\n* History of thoracic or abdominal surgery.\n* Presence of another neuromuscular disorder.\n* Aphasia or cognitive impairment preventing participation in assessments.\n* Active malignancy.\n\nInclusion Criteria (Healthy Control Group):\n\n* Age between 18 and 75 years.\n* Willingness to participate in the study.\n* Provision of written informed consent.\n\nExclusion Criteria (Healthy Control Group):\n\n* History of stroke or other neurological disorders.\n* History of chronic respiratory disease (e.g., COPD, asthma).\n* Chest wall deformity.\n* Presence of systemic diseases that may affect muscle function.",{"count":162,"type":22},65,"The aim of this study is to evaluate the morphological and functional characteristics of parasternal intercostal muscles in patients with stroke using ultrasonography. Parasternal intercostal muscle thickness and thickening fraction will be assessed on both the hemiplegic and non-hemiplegic sides. The relationship between ultrasonographic findings and respiratory muscle strength, motor function, balance, functional independence, and quality of life will also be investigated. A healthy control group will be included to establish reference values and enable comparative analyses.",[165],"Stroke",[167,168,169,71],"stroke","intercostal muscle thickness","interkostal muscle thickening",{"date":113,"type":46},{"date":151,"type":22},{"date":173,"type":22},"2026-10-01",{"name":52,"class":53},{"id":176,"slug":177,"hasResults":12,"nctId":178,"briefTitle":179,"officialTitle":180,"acronym":181,"eligibilityCriteria":182,"healthyVolunteers":92,"sex":183,"minAge":184,"maxAge":93,"enrollmentInfo":185,"targetDuration":4,"studyType":96,"phases":187,"briefSummary":188,"conditions":189,"keywords":198,"overallStatus":147,"whyStopped":4,"lastUpdateSubmitDate":116,"lastUpdatePostDateStruct":199,"startDateStruct":201,"completionDateStruct":203,"leadSponsor":205,"locationsCount":4},"100623836","fascial-yoga-in-menopausal-women-100623836","NCT07401810","Fascial Yoga in Menopausal Women","The Effect of Fascial Yoga on Perceived Stress, Cognitive Control, and Cognitive Flexibility in Menopausal Women","FascialYogaM","Inclusion Criteria:\n\n* Female participants aged 45-65 years\n* In the menopausal period, defined as at least 12 months since the last menstrual period\n* Able to read and understand Turkish and to complete self-report questionnaires\n\nExclusion Criteria:\n\n* Current or past diagnosis of a psychiatric disorder or ongoing psychiatric treatment\n* Regular use of antidepressant, anxiolytic, or corticosteroid medications\n* History of cancer or currently receiving active oncological treatment\n* Participation in facial yoga or similar yoga-based programs within the past 6 months\n* Any medical condition that may prevent safe participation in mild physical activity\n* Incomplete attendance to intervention sessions or incomplete outcome data during the study period","FEMALE","45 Years",{"count":186,"type":22},100,[98],"Aim:\n\nThe aim of this study is to evaluate the effects of a structured fascial yoga-based behavioral intervention on perceived stress, cognitive control, and cognitive flexibility in menopausal women. The study aims to determine whether a non-pharmacological and non-invasive behavioral intervention can support psychological and cognitive functioning and reduce perceived stress in menopausal women.\n\nDesign:\n\nThis study is designed as a randomized controlled, pretest-posttest experimental study with a post-intervention follow-up assessment. Eligible participants will be randomly assigned to either the intervention group or the control group receiving usual care. Outcomes will be assessed at baseline, immediately after the intervention, and at follow-up to evaluate both the immediate and sustained effects of the intervention.\n\nMethod:\n\nA total of 100 menopausal women aged 45-65 years will be recruited from the menopause outpatient clinic and randomly assigned to either the intervention group or the control group. The intervention group will participate in a 12-week online fascial yoga program consisting of two 60-minute sessions per week.\n\nIn this study, fascial yoga is defined as a fascia-focused, non-pharmacological, and non-invasive behavioral intervention that includes myofascial release techniques, breath regulation, body awareness, and basic yoga practices to support stress regulation and cognitive functioning. The program will include myofascial release techniques, basic yoga postures suitable for all physical fitness levels, and structured breathing exercises. All sessions will be conducted online in a group format, and no audio or video recordings will be taken.\n\nThe control group will continue to receive routine outpatient care during the study period. After completion of the follow-up assessments, the fascial yoga program will be offered to participants in the control group upon request.\n\nData will be collected at three time points: at baseline before the intervention, immediately after completion of the 12-week intervention, and at the follow-up assessment 8 weeks after the intervention. Perceived stress, cognitive control, and cognitive flexibility will be assessed using validated self-report questionnaires.\n\nHypotheses:\n\nH1: Menopausal women participating in the fascial yoga intervention will show a significant reduction in perceived stress levels compared with the control group at post-intervention and follow-up assessments.\n\nH2: Menopausal women participating in the fascial yoga intervention will show a significant improvement in cognitive control and cognitive flexibility compared with the control group at post-intervention and follow-up assessments.",[190,191,192,193,194,195,196,197],"Menopause","Stress, Psychological","Cognitive Flexibility","Nonpharmacological Interventions","Randomized Controlled Trial","Cognitive Control","Perceived Stress","Yoga",[190,196,192,195,197],{"date":200,"type":46},"2026-06-17",{"date":202,"type":22},"2026-07-01",{"date":204,"type":22},"2027-06-01",{"name":52,"class":53},{"id":207,"slug":208,"hasResults":12,"nctId":209,"briefTitle":210,"officialTitle":211,"acronym":4,"eligibilityCriteria":212,"healthyVolunteers":12,"sex":17,"minAge":61,"maxAge":93,"enrollmentInfo":213,"targetDuration":4,"studyType":96,"phases":215,"briefSummary":216,"conditions":217,"keywords":219,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":223,"lastUpdatePostDateStruct":224,"startDateStruct":225,"completionDateStruct":227,"leadSponsor":229,"locationsCount":54},"100641914","transcutaneous-auricular-vagus-nerve-stimulation-in-psoriatic-arthritis-100641914","NCT07653009","Transcutaneous Auricular Vagus Nerve Stimulation in Psoriatic Arthritis","The Effect of Transcutaneous Auricular Vagus Nerve Stimulation on Disease Activity and Related Clinical Parameters in Patients With Psoriatic Arthritis","Inclusion Criteria:\n\n* Diagnosis of psoriatic arthritis according to the CASPAR criteria\n* Age between 18 and 65 years\n* Stable treatment regimen for at least 12 weeks prior to enrollment\n* Visual Analog Scale (VAS) pain score ≥4 on a 0-10 scale\n* Moderate-to-high disease activity according to the Disease Activity Index for Psoriatic Arthritis (DAPSA)\n* Ability and willingness to provide written informed consent\n\nExclusion Criteria:\n\n* Presence of an implanted cardiac device (e.g., pacemaker, implantable cardioverter-defibrillator) or implanted neurostimulator\n* History of epilepsy or other uncontrolled neurological disorders\n* Active severe infection or immunosuppressive condition (e.g., sepsis)\n* Pregnancy or breastfeeding\n* Presence of deep auricular injury, previous ear surgery, or active skin lesions involving the auricle\n* Inability to comply with the treatment protocol or history of severe psychiatric disorders",{"count":214,"type":22},15,[98],"This prospective single-center interventional study aims to investigate the effects of transcutaneous auricular vagus nerve stimulation (taVNS) on disease activity, pain, quality of life, autonomic dysfunction symptoms, and inflammatory biomarkers in patients with psoriatic arthritis (PsA). Participants diagnosed with PsA according to the Classification Criteria for Psoriatic Arthritis (CASPAR) will undergo non-invasive auricular vagus nerve stimulation using the Vagustim device. Clinical outcomes including the Disease Activity Index for Psoriatic Arthritis (DAPSA), Ankylosing Spondylitis Disease Activity Score based on C-reactive protein (ASDAS-CRP), Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), pain scores, sleep quality, quality of life, anxiety\u002Fdepression, and inflammatory markers including C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) will be evaluated before and after treatment.",[218],"Psoriatic Arthritis",[220,221,222],"Transcutaneous Auricular Vagus Nerve Stimulation","Vagus Nerve Stimulation","Autonomic Dysfunction Disease Activity","2026-06-11",{"date":200,"type":46},{"date":226,"type":46},"2026-06-02",{"date":228,"type":22},"2027-08-02",{"name":52,"class":53},{"id":231,"slug":232,"hasResults":12,"nctId":233,"briefTitle":234,"officialTitle":235,"acronym":4,"eligibilityCriteria":236,"healthyVolunteers":12,"sex":17,"minAge":61,"maxAge":93,"enrollmentInfo":237,"targetDuration":4,"studyType":96,"phases":239,"briefSummary":240,"conditions":241,"keywords":249,"overallStatus":147,"whyStopped":4,"lastUpdateSubmitDate":256,"lastUpdatePostDateStruct":257,"startDateStruct":259,"completionDateStruct":261,"leadSponsor":263,"locationsCount":54},"100637561","hyaluronic-acid-as-an-adjunct-to-non-surgical-periodontal-therapy-in-smokers-100637561","NCT07597213","Hyaluronic Acid as an Adjunct to Non-Surgical Periodontal Therapy in Smokers","The Effect of Adjunctive Use of Hyaluronic Acid in Non-Surgical Periodontal Treatment in Smoking Patients","Inclusion Criteria:\n\n1. Individuals who sign the informed consent form\n2. Participants who are systemically healthy\n3. Participants who smoke (for \\>5 years and ≥10 cigarettes per day)\n4. Participants diagnosed with Stage III or Stage IV periodontitis\n5. Participants with at least 20 natural teeth present in the mouth (excluding third molars)\n6. Participants with two non-adjacent interproximal sites in each quadrant of either jaw, presenting probing depth (PD) and clinical attachment level (CAL) ≥6 mm, and with no caries, restorations, or furcation involvement\n\nExclusion Criteria:\n\n1. Individuals who do not sign the informed consent form\n2. Individuals having any systemic disease\n3. Participants who have used antibiotics within the last 3 months\n4. Participants who have received any periodontal treatment within 6 months prior to the study\n5. Participants who are pregnant or lactating",{"count":238,"type":22},23,[98],"The goal of this clinical trial is to evaluate whether hyaluronic acid (HA) improves periodontal healing in people with periodontal disease who smoke. Moreover, the effects of HA on biomolecules and bacteria levels will be assessed during the follow up period.\n\nThe main questions it will answer are:\n\nWill periodontal sites treated with HA gel after non-surgical periodontal treatment (NSPT) lead to better outcomes in clinical parameters compared to the sites treated with NSPT only in smokers?\n\nWill adjunctive use of HA gel reduce oxidative stress markers and bacteria levels during follow-up?\n\nResearchers will compare periodontal sites receiving NSPT with adjunctive HA gel application to sites receiving NSPT alone to determine whether HA provides additional clinical, biochemical and microbiological benefits.\n\nParticipants will:\n\n* first receive full-mouth NSPT then, randomization will be performed in selected jaw to determine the test sites. These two interproximal test sites will additionally receive HA gel application.\n* attend follow-up visits at 1, 3 and 6 months for clinical periodontal measurements and to provide gingival crevicular fluid samples (GCF) and subgingival samples.\n\nThe GCF samples will be evaluated for Metallothionein (MT) and 8-hydroxy-2'-deoxyguanosine (8-OHdG) levels and subgingival samples for periodontal pathogens.",[242,243,244,245,246,247,248],"Hyaluronic Acid","Periodontal Therapy","Oral Microbiota","Oxidative Stress","Metallothionein","8-OHdG","Periodontitis",[250,251,252,253,247,254,255],"hyaluronic acid","periodontitis","periodontal pathogens","metallothionein","Non-surgical periodontal treatment","split-mouth study","2026-06-03",{"date":258,"type":46},"2026-06-05",{"date":260,"type":22},"2026-06",{"date":262,"type":22},"2028-07",{"name":52,"class":53},{"id":265,"slug":266,"hasResults":12,"nctId":267,"briefTitle":268,"officialTitle":269,"acronym":4,"eligibilityCriteria":270,"healthyVolunteers":12,"sex":17,"minAge":61,"maxAge":93,"enrollmentInfo":271,"targetDuration":4,"studyType":96,"phases":272,"briefSummary":273,"conditions":274,"keywords":278,"overallStatus":147,"whyStopped":4,"lastUpdateSubmitDate":226,"lastUpdatePostDateStruct":282,"startDateStruct":284,"completionDateStruct":285,"leadSponsor":286,"locationsCount":54},"100643782","adjunctive-hyaluronic-acid-gel-in-non-surgical-periodontal-treatment-of-patients-with-diabetes-mellitus-100643782","NCT07631273","Adjunctive Hyaluronic Acid Gel in Non-Surgical Periodontal Treatment of Patients With Diabetes Mellitus","The Effect of Hyaluronic Acid on Non-Surgical Periodontal Treatment in Patients With Diabetes Mellitus","Inclusion Criteria:\n\n* Individuals who sign the informed consent form\n* Participants diagnosed with diabetes mellitus (HbA1c %7-7.9)\n* Participants without any systemic disease other than DM\n* Participants diagnosed with Stage III or Stage IV periodontitis\n* Nonsmokers\n* Participants with at least 15 natural teeth present in the mouth (excluding third molars)\n* Participants in either of the jaws, in both quadrants, having two non-adjacent interproximal sites with probing depth and clinical attachment level ≥6 mm with no caries, restorations or furcation involvement\n\nExclusion Criteria:\n\n* Individuals who do not sign the informed consent form\n* Ongoing drug therapy that might have an impact on the clinical signs and symptoms of periodontitis\n* Participants have received any periodontal treatment within 6 months prior to the study\n* Participants who have used antibiotics within the last 3 months\n* Smokers\n* Participants who are pregnant or lactating",{"count":238,"type":22},[98],"The goal of this clinical trial is to evaluate whether the adjunctive use of hyaluronic acid (HA) improves periodontal healing in people with diabetes mellitus and periodontitis. The effects of HA on biomolecules and bacteria levels will be assessed during the follow-up period.\n\nThe main questions the study will answer are:\n\n* Will periodontal sites treated with non-surgical periodontal treatment (NSPT) plus HA gel show better clinical periodontal parameters than sites treated with only NSPT in patients with diabetes and periodontitis?\n* will HA gel have additional effect on reducing inflammation or collagen markers, and bacteria levels during follow-up?\n\nResearchers will compare periodontal sites receiving NSPT with adjunctive HA gel application to sites receiving NSPT alone to determine whether HA provides additional clinical, biochemical and microbiological benefits.\n\nParticipants will:\n\n* provide recent HbA1c test results.\n* then, the participants will receive full-mouth NSPT then, randomization will be performed for the selected jaw for test sites. These two interproximal test sites will additionally receive HA application.\n* attend follow-up visits at 1, 3 and 6 months for clinical periodontal measurements and to provide gingival crevicular fluid samples (GCF) and subgingival samples.\n\nThe GCF samples will be evaluated for interleukin-34 (IL-34) and beta C-terminal telopeptide (β-CTX) levels and subgingival samples for periodontal pathogens.",[248,275,242,244,276,277],"Diabetes Mellitus","IL-34","β-CTX",[248,279,280,242,281,276,277,252],"diabetes mellitus","Non-surgical Periodontal Treatment","Split-mouth Study",{"date":283,"type":46},"2026-06-08",{"date":260,"type":22},{"date":262,"type":22},{"name":52,"class":53},{"id":288,"slug":289,"hasResults":12,"nctId":290,"briefTitle":291,"officialTitle":292,"acronym":4,"eligibilityCriteria":293,"healthyVolunteers":92,"sex":17,"minAge":294,"maxAge":295,"enrollmentInfo":296,"targetDuration":4,"studyType":96,"phases":298,"briefSummary":299,"conditions":300,"keywords":4,"overallStatus":147,"whyStopped":4,"lastUpdateSubmitDate":226,"lastUpdatePostDateStruct":305,"startDateStruct":307,"completionDateStruct":309,"leadSponsor":311,"locationsCount":4},"100640792","evaluation-of-occlusal-force-and-masticatory-function-in-children-with-molar-incisor-hypomineralization-100640792","NCT07589179","Evaluation of Occlusal Force and Masticatory Function in Children With Molar-Incisor Hypomineralization","Evaluation of Occlusal Force Distribution and Masticatory Function Before and After Restorative Treatment in Children With Molar-Incisor Hypomineralization","Inclusion Criteria:\n\n* Children aged 7 to 12 years\n* Presence of bilateral molar-incisor hypomineralization (MIH) affecting first permanent molars\n* Need for restorative treatment in MIH-affected molars\n* Cooperative children with sufficient cognitive ability to complete functional assessments\n* Presence of healthy control participants without MIH for comparison\n* Mixed dentition period\n* Signed informed consent obtained from parents or legal guardians\n\nExclusion Criteria:\n\n* Temporomandibular disorders or orofacial pain\n* Systemic diseases or regular medication use affecting mastication\n* History of orthodontic treatment or parafunctional habits\n* Craniofacial anomalies or developmental dental anomalies\n* Extensive prosthetic restorations affecting chewing function\n* Uncooperative children unable to complete examination procedures\n* Acute dental infection or pain requiring emergency treatment","7 Years","13 Years",{"count":297,"type":22},68,[98],"This study aims to evaluate right-left chewing balance and masticatory function in children with Molar-Incisor Hypomineralization (MIH) before and after restorative treatment. MIH is a developmental enamel defect that may cause tooth sensitivity, discomfort during chewing, and functional asymmetry.\n\nChildren aged 7 to 12 years with bilateral MIH affecting the first permanent molars will receive glass hybrid restorative treatment. Right-left occlusal force distribution will be assessed using a digital occlusal analysis system. In addition, chewing side preference and chewing balance will be evaluated using a standardized chewing gum protocol. These two assessment methods will be used together to provide complementary information about masticatory function.\n\nMeasurements will be performed before treatment and during follow-up visits after treatment. The findings obtained from children with MIH will also be compared with healthy children without MIH. The study aims to determine whether restorative treatment improves chewing balance and functional oral performance in children with MIH.",[301,302,303,304],"Molar-Incisor Hypomineralization (MIH)","Masticatory Performance","Occlusal Analysis","Chewing Function",{"date":306,"type":46},"2026-06-04",{"date":308,"type":22},"2026-05-11",{"date":310,"type":22},"2026-12-20",{"name":52,"class":53},{"id":313,"slug":314,"hasResults":12,"nctId":315,"briefTitle":316,"officialTitle":316,"acronym":4,"eligibilityCriteria":317,"healthyVolunteers":12,"sex":17,"minAge":61,"maxAge":93,"enrollmentInfo":318,"targetDuration":4,"studyType":96,"phases":319,"briefSummary":320,"conditions":321,"keywords":325,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":226,"lastUpdatePostDateStruct":330,"startDateStruct":331,"completionDateStruct":332,"leadSponsor":334,"locationsCount":54},"100643353","efficacy-of-the-erector-spinae-plane-block-for-persistent-back-pain-in-patients-with-ankylosing-spondylitis-100643353","NCT07633730","Efficacy of the Erector Spinae Plane Block for Persistent Back Pain in Patients With Ankylosing Spondylitis","Inclusion Criteria:\n\n* Age between 18 and 65 years\n* Diagnosis of ankylosing spondylitis according to the Modified New York Criteria\n* Patients receiving ongoing treatment with controlled disease activity but persistent back pain\n* Willingness to participate in the study\n\nExclusion Criteria:\n\n* Body mass index (BMI) greater than 35 kg\u002Fm²\n* History of thoracic surgery\n* Intellectual disability or mental retardation\n* Presence of major psychiatric comorbidity\n* Congenital spinal anomaly\n* Pregnancy\n* History of bleeding diathesis\n* Presence of active local and\u002For systemic infection\n* Known allergy to the medications to be injected\n* Hemodynamic instability\n* Active phase of the disease (elevated acute phase reactants, active arthritis findings, etc.)",{"count":214,"type":22},[98],"Despite adequate control of disease activity with standard medical therapies, there remains an ongoing need for complementary and interventional approaches for the management of persistent back pain in patients with ankylosing spondylitis. Although the erector spinae plane block has been described in the literature as a safe and effective analgesic intervention for chronic back pain in various patient populations, to the best of our knowledge, no clinical study has specifically evaluated its use for persistent back pain in patients with ankylosing spondylitis receiving medical treatment. Therefore, the present study aims to evaluate the effects of erector spinae plane block on pain severity and clinical outcomes in patients with ankylosing spondylitis whose disease activity is controlled under treatment but who continue to experience persistent back pain.",[322,323,324,41],"Ankylosing Spondylitis (AS)","Back Pain","ESPB",[324,326,323,327,328,329],"Erector Spinae Plane Block","Ankylosing Spondylitis","Persistent back pain","Regional anesthesia",{"date":283,"type":46},{"date":226,"type":46},{"date":333,"type":22},"2027-06-02",{"name":52,"class":53},{"id":336,"slug":337,"hasResults":12,"nctId":338,"briefTitle":339,"officialTitle":339,"acronym":4,"eligibilityCriteria":340,"healthyVolunteers":92,"sex":17,"minAge":61,"maxAge":93,"enrollmentInfo":341,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":343,"conditions":344,"keywords":351,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":226,"lastUpdatePostDateStruct":358,"startDateStruct":359,"completionDateStruct":361,"leadSponsor":362,"locationsCount":54},"100617479","assessment-of-upper-extremity-proprioception-in-patients-with-cervical-radiculopathy-100617479","NCT07319156","Assessment of Upper Extremity Proprioception in Patients With Cervical Radiculopathy","Inclusion Criteria:\n\n* Being between 18 and 65 years of age\n* Presence of radicular pain diagnosed through clinical examination and cervical -MRI imaging Patients with cervical MRI findings demonstrating cervical disc herniation at least at one level consistent with their symptoms\n* Willingness to participate in the study\n\nExclusion Criteria:\n\n* History of cervical physical therapy within the past year\n* Symptoms or diagnosis of upper-extremity entrapment neuropathy\n* Patients with documented vitamin B12 or vitamin D deficiency within the last 2 years in available medical records\n* History of cervical surgery or cervical trauma\n* History of upper-extremity surgery or trauma\n* Individuals with intellectual disability\n* Presence of major psychiatric comorbidity\n* Diagnosis of polyneuropathy\n* Diagnosis of Diabetes Mellitus\n* Diagnosis of fibromyalgia\n* Use of medications that may impair proprioception\n* Pregnancy\n* Refusal to provide informed consent",{"count":342,"type":22},58,"There is no study in the current literature that systematically investigates the extent of upper-extremity proprioceptive impairment in patients with radicular neuropathic symptoms secondary to cervical disc herniation, nor its association with clinical findings. Although existing reviews emphasize proprioceptive deficits in populations with neck pain or cervical spondylosis, no studies specifically address the subgroup of cervical disc-related radiculopathy. This gap in knowledge hinders the integration of proprioceptive assessments with upper-extremity functional outcome measures in diagnostic and rehabilitative processes, suggesting a need for more specific data to guide sensory-motor training approaches. The primary aim of the present study is to assess upper-extremity proprioception in patients with cervical radiculopathy by comparing them with a healthy control group. The secondary aim is to examine the relationship between upper-extremity proprioception and clinical outcomes, including parameters such as pain and functional status.",[345,346,347,348,349,350],"Cervical Radiculopathy","Proprioception","Cervical Disc Herniation","Proprioception Reaching Test","Pro-reach","Upper Extremity",[352,353,354,355,356,357],"cervical radiculopathy","proprioception","cervical disc herniation","proprioception reaching test","pro-reach","upper extremity",{"date":306,"type":46},{"date":360,"type":46},"2025-12-20",{"date":310,"type":22},{"name":52,"class":53},{"id":364,"slug":365,"hasResults":12,"nctId":366,"briefTitle":367,"officialTitle":368,"acronym":4,"eligibilityCriteria":369,"healthyVolunteers":12,"sex":17,"minAge":370,"maxAge":62,"enrollmentInfo":371,"targetDuration":4,"studyType":96,"phases":373,"briefSummary":374,"conditions":375,"keywords":377,"overallStatus":147,"whyStopped":4,"lastUpdateSubmitDate":383,"lastUpdatePostDateStruct":384,"startDateStruct":386,"completionDateStruct":388,"leadSponsor":390,"locationsCount":54},"100640258","hybrid-vs-fluoroscopy-guided-interlaminar-epidural-injection-in-lumbar-spinal-stenosis-100640258","NCT07612982","Hybrid vs Fluoroscopy-Guided Interlaminar Epidural Injection in Lumbar Spinal Stenosis","Comparison of Hybrid and Fluoroscopy-Guided Interlaminar Epidural Steroid Injections on Patient Satisfaction, Radiation Dose and Procedure Time in Lumbar Spinal Stenosis","Inclusion Criteria:\n\n* Age between 40 and 75 years\n* Diagnosis of lumbar spinal stenosis confirmed by clinical evaluation and magnetic resonance imaging (MRI)\n* Presence of neurogenic claudication symptoms for at least 3 months\n* Inadequate response to conservative treatment, including medication, physical therapy, or exercise\n* Numeric Rating Scale (NRS) pain score ≥ 4 at baseline\n* Ability to provide written informed consent\n\nExclusion Criteria:\n\n* Previous lumbar spine surgery\n* Vertebral fracture, spinal malignancy, or history of significant lumbar trauma\n* Peripheral vascular claudication or clinically significant peripheral polyneuropathy\n* Epidural steroid injection within the past 6 months\n* Medical conditions severely limiting ambulation unrelated to lumbar spinal stenosis (e.g., severe cardiopulmonary disease or advanced hip\u002Fknee osteoarthritis)\n* Pregnancy or breastfeeding\n* Coagulation disorders or inability to safely discontinue anticoagulant or antiplatelet therapy according to guideline recommendations\n* Known allergy to local anesthetics, corticosteroids, or contrast agents\n* Active local or systemic infection\n* Body mass index (BMI) \\> 30 kg\u002Fm²","40 Years",{"count":372,"type":22},44,[98],"Lumbar spinal stenosis is a common degenerative condition that can cause chronic low back and leg pain, especially during walking or standing. Interlaminar epidural steroid injections are widely used to relieve pain and improve function in patients who do not respond adequately to conservative treatments.\n\nThese injections are usually performed under fluoroscopic guidance, which allows accurate needle placement but exposes patients and healthcare providers to ionizing radiation. Ultrasound guidance has emerged as an alternative technique that avoids radiation exposure; however, ultrasound alone may not always confirm correct epidural spread of the injected medication.\n\nThis prospective, randomized clinical trial aims to compare two commonly used imaging approaches for interlaminar epidural steroid injections in patients with lumbar spinal stenosis: fluoroscopy-guided injection and ultrasound-guided injection with fluoroscopic confirmation (hybrid technique). The study will evaluate patient satisfaction, radiation exposure, procedure time, technical success, pain relief, and functional outcomes.\n\nThe results of this study are expected to help identify the most effective and safe imaging guidance method for interlaminar epidural steroid injections in patients with lumbar spinal stenosis.",[376],"Lumbar Spinal Stenosis",[378,379,380,381,382],"Fluoroscopy","Radiation exposure","Patient satisfaction","Interventional Ultrasonography","Epidural Injections","2026-05-28",{"date":385,"type":46},"2026-05-29",{"date":387,"type":22},"2026-07",{"date":389,"type":22},"2027-01",{"name":52,"class":53},{"id":392,"slug":393,"hasResults":12,"nctId":394,"briefTitle":395,"officialTitle":396,"acronym":397,"eligibilityCriteria":398,"healthyVolunteers":12,"sex":17,"minAge":61,"maxAge":4,"enrollmentInfo":399,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":401,"conditions":402,"keywords":407,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":414,"lastUpdatePostDateStruct":415,"startDateStruct":417,"completionDateStruct":418,"leadSponsor":419,"locationsCount":54},"100616030","validation-of-sofa-2-for-mortality-and-sepsis-3-prevalence-in-turkey-100616030","NCT07300306","Validation of SOFA-2 for Mortality and Sepsis-3 Prevalence in Turkey","Validation of the SOFA-2 Score for 30-Day Mortality in Intensive Care Units in Turkey and Determination of Sepsis-3 Prevalence - A Multicenter Hybrid Observational Study.","TURK-SOFA2","Inclusion Criteria:\n\n* Patients aged 18 years or older.\n* Admitted to the Intensive Care Unit (ICU) during the specified study recruitment window.\n* For the Validation Cohort: Patients staying in the ICU for at least 24 hours.\n* For the Point Prevalence Cohort: Patients present in the ICU at 08:00 AM on the designated \"Index Day\" or admitted within the subsequent 24 hours.\n\nExclusion Criteria:\n\n* Patients younger than 18 years of age.\n* Patients admitted to Pediatric Intensive Care Units.\n* Patients admitted to Coronary Care Units (CCU).\n* Patients admitted to Cardiovascular Surgery Intensive Care Units.\n* Patients admitted solely for the purpose of organ donation.\n* Patients with missing core data components required for score calculation.",{"count":400,"type":22},2500,"The goal of this observational study is to validate the effectiveness of the new SOFA-2 score in predicting mortality and to determine the current frequency of sepsis in adult patients admitted to Intensive Care Units (ICUs) in Turkey. The main questions it aims to answer are:\n\n* Does the SOFA-2 score accurately predict 30-day mortality in ICU patients?\n* What is the prevalence of Sepsis-3 and septic shock in Turkish ICUs?\n\nResearchers will compare the new SOFA-2 score to the existing SOFA-1 score to see if the new score provides better predictive accuracy for patient outcomes.\n\nParticipants will not receive any experimental intervention. Researchers will collect data from routine medical care, including:\n\n* Vital signs, laboratory test results, and details of organ support (such as mechanical ventilation or dialysis) during the first 24 hours of admission.\n* Survival status at 30 days.",[403,404,405,406],"Sepsis","Septic Shock","Critical Illness","Organ Dysfunction",[408,409,410,411,412,413],"SOFA-2 Score","Sepsis-3","Intensive Care Unit","Mortality Prediction","Organ Failure Assessment","Validation Study","2026-05-04",{"date":416,"type":46},"2026-05-08",{"date":414,"type":46},{"date":387,"type":22},{"name":52,"class":53},{"id":421,"slug":422,"hasResults":12,"nctId":423,"briefTitle":424,"officialTitle":425,"acronym":4,"eligibilityCriteria":426,"healthyVolunteers":12,"sex":17,"minAge":61,"maxAge":93,"enrollmentInfo":427,"targetDuration":4,"studyType":96,"phases":429,"briefSummary":430,"conditions":431,"keywords":433,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":440,"lastUpdatePostDateStruct":441,"startDateStruct":443,"completionDateStruct":445,"leadSponsor":447,"locationsCount":54},"100634108","telerehabilitation-in-patients-with-elevated-pulmonary-artery-pressure-100634108","NCT07535398","Telerehabilitation in Patients With Elevated Pulmonary Artery Pressure","The Effectiveness of Telerehabilitation in Patients With Elevated Pulmonary Artery Pressure","Inclusion Criteria:\n\n* Adults aged 18 to 65 years\n* Elevated pulmonary artery pressure identified by echocardiography, defined as systolic pulmonary artery pressure (sPAP) of 50 mmHg or higher\n* Clinically stable and receiving medical treatment under cardiology follow-up World Health Organization functional class I or II\n* New York Heart Association (NYHA) functional class I or II\n* Living with a caregiver, family member, or another person who can provide assistance if needed\n* Access to the internet and adequate visual, cognitive, and functional ability to participate in videoconference-based sessions\n* Willing to participate and able to provide informed consent\n\nExclusion Criteria:\n\n* Requirement for oxygen therapy\n* Musculoskeletal problems limiting participation in exercise\n* Ongoing treatment for psychiatric or psychological disorders\n* Cognitive impairment based on Mini-Mental State Examination findings\n* Severe chronic obstructive pulmonary disease (COPD)\n* Other significant cardiac disease that may interfere with participation or assessment",{"count":428,"type":22},12,[98],"The goal of this clinical trial is to learn if synchronous telerehabilitation is effective in patients with elevated pulmonary artery pressure identified by echocardiography (systolic pulmonary artery pressure ≥50 mmHg). It will also evaluate the effects of telerehabilitation on exercise capacity, dyspnea, fatigue, functional status, and quality of life. The main questions it aims to answer are:\n\nDoes synchronous telerehabilitation improve exercise and functional capacity in these patients? Does synchronous telerehabilitation improve dyspnea, fatigue, psychological status, and quality of life?\n\nResearchers will compare synchronous telerehabilitation with breathing and posture exercises to see if telerehabilitation provides greater clinical and functional benefit.\n\nParticipants will:\n\nBe randomly assigned to one of 2 groups Follow an 8-week program, 3 times per week, for 30 minutes per session Perform aerobic, endurance, and strengthening exercises by synchronous telerehabilitation, or breathing and posture exercises in the control group Complete assessments before and after treatment",[432],"Elevated Pulmonary Artery Pressure",[434,435,436,437,438,439],"Elevated pulmonary artery pressure","pulmonary hypertension","synchronous telerehabilitation","exercise capacity","pulmonary function","quality of life","2026-04-27",{"date":442,"type":46},"2026-04-29",{"date":444,"type":22},"2026-04",{"date":446,"type":22},"2026-08",{"name":52,"class":53},{"id":449,"slug":450,"hasResults":12,"nctId":451,"briefTitle":452,"officialTitle":453,"acronym":4,"eligibilityCriteria":454,"healthyVolunteers":92,"sex":17,"minAge":61,"maxAge":4,"enrollmentInfo":455,"targetDuration":4,"studyType":96,"phases":457,"briefSummary":458,"conditions":459,"keywords":461,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":440,"lastUpdatePostDateStruct":467,"startDateStruct":469,"completionDateStruct":471,"leadSponsor":473,"locationsCount":54},"100617560","physiological-and-neurocognitive-responses-to-multisensory-food-cues-in-vr-100617560","NCT07320209","Physiological and Neurocognitive Responses to Multisensory Food Cues in VR","Investigation of Physiological and Neurocognitive Responses to Multisensory Food Cues in an Virtual Reality Environment","Inclusion Criteria:\n\n* Being over 18 years of age.\n* Individuals with a normal Body Mass Index according to the WHO classification.\n* No known food allergies or eating disorder diagnoses.\n* Voluntarily agree to participate in the study and sign an informed consent form.\n* Be physically and psychologically suitable for virtual reality environment and electroencephalography (EEG) recording applications.\n\nExclusion Criteria:\n\n* History of any neurological disease (e.g., epilepsy, vertigo) that may prevent the use of virtual reality goggles\n* Allergy, intolerance, or sensitivity to foods used in the experimental procedure (e.g., chocolate biscuits, pickles)\n* Significant loss or impairment of vision, hearing, or sense of smell.\n* Sensitivity to the use of virtual reality devices (e.g. history of cyber sickness such as nausea, dizziness, etc.)\n* Use of psychiatric medication, antidepressants, neuroleptics, or medication that may affect neurological status\n* History of psychological conditions that may affect the working process, such as attention deficit, anxiety disorder, or panic attacks.\n* Any discomfort in the salivary glands, insufficient saliva production, or dry mouth.\n* Consumption of more than 21 units of alcohol per week (as this may affect food cravings and physiological parameters).\n* History or diagnosis of abnormal brain electrical activity that may affect EEG measurements.\n* History of substance dependence or any mental disorder that may affect cortical activity.\n* Conditions that prevent body composition analysis (BIA) measurements (e.g. use of a pacemaker, limb amputation, lymphoedema, etc.).\n* The presence of any language or cognitive barrier that prevents communication.",{"count":456,"type":22},34,[98],"This study aims to investigate how food cravings change when visual food cues are enriched with sound, smell, and interactive experiences in a virtual reality (VR) environment. A total of 34 healthy Marmara University students aged 18 and older will participate in the study between November 2025 and March 2026, with a possible extension until September 2026.\n\nParticipants will be exposed to real, virtual, and multisensory food cues, and their food craving levels, saliva composition, blood glucose, EEG activity, and body temperature will be measured. Salivary alpha-amylase will be analysed as a biomarker of physiological arousal during food cue exposure.\n\nThe study aims to compare how virtual food cues affect food craving and physiological responses compared to real food cues. Findings are expected to contribute to understanding eating behaviour, developing VR-based interventions for healthy nutrition, and encouraging interdisciplinary collaboration between nutrition and engineering fields.",[460],"Healthy Participants",[462,463,464,465,466],"Food cue","human-computer interaction","food craving","salivary composition","EEG",{"date":468,"type":46},"2026-04-28",{"date":470,"type":46},"2026-04-01",{"date":472,"type":22},"2026-10-30",{"name":52,"class":53},{"id":475,"slug":476,"hasResults":12,"nctId":477,"briefTitle":478,"officialTitle":479,"acronym":4,"eligibilityCriteria":480,"healthyVolunteers":12,"sex":17,"minAge":61,"maxAge":4,"enrollmentInfo":481,"targetDuration":483,"studyType":24,"phases":4,"briefSummary":484,"conditions":485,"keywords":489,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":440,"lastUpdatePostDateStruct":494,"startDateStruct":496,"completionDateStruct":498,"leadSponsor":500,"locationsCount":54},"100598224","nutritional-status-of-head-and-neck-cancer-patients-100598224","NCT07068711","Nutritional Status of Head and Neck Cancer Patients","Monitoring the Nutritional Status of Head and Neck Cancer Patients During Radiotherapy","Inclusion Criteria:\n\n* Patients aged 18 years and older\n* Diagnosed with head and neck cancer\n* Receiving radiotherapy at Marmara University Pendik Training and Research Hospital, Radiation Oncology Clinic\n* Willing to participate and able to provide written informed consent\n* Able to communicate and cooperate during assessments\n\nExclusion Criteria:\n\n* Patients for whom BIA measurement is not possible (e.g., caffeine intake within the last 4 hours, alcohol use in the last 24 hours, intense physical activity in the last 24-48 hours, menstruation, presence of pacemaker or metal implants)\n* Patients with communication barriers or cognitive impairments\n* Amputees or individuals with severe upper extremity deformities\n* Patients with neuromuscular disorders, hemiplegia, rheumatoid arthritis, or moderate\u002Fsevere neurological or cognitive impairment\n* Patients receiving parenteral nutrition",{"count":482,"type":22},57,"10 Weeks","This study aims to monitor the nutritional status of patients with head and neck cancer undergoing radiotherapy treatment. Throughout the treatment process, patients' body composition, handgrip strength, food intake, quality of life, and treatment-related side effects will be regularly assessed. Measurements will include physical parameters like body weight, height, and waist circumference, as well as blood test results and nutrition-related questionnaires. By closely tracking these changes, the study seeks to identify early signs of nutritional deterioration and support timely interventions. The goal is to better understand nutrition-related challenges during treatment and ultimately improve patients' quality of life.",[486,487,488],"Head and Neck Cancer","Radiotherapy","Nutritional Status",[490,491,492,439,493],"head and neck cancer","radiotherapy","nutritional status","adverse events",{"date":495,"type":46},"2026-05-01",{"date":497,"type":46},"2025-07-01",{"date":499,"type":22},"2026-09-01",{"name":52,"class":53},{"id":502,"slug":503,"hasResults":12,"nctId":504,"briefTitle":505,"officialTitle":506,"acronym":507,"eligibilityCriteria":508,"healthyVolunteers":12,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":509,"targetDuration":511,"studyType":24,"phases":4,"briefSummary":512,"conditions":513,"keywords":516,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":521,"lastUpdatePostDateStruct":522,"startDateStruct":524,"completionDateStruct":526,"leadSponsor":528,"locationsCount":529},"100635876","global-initiative-on-takayasu-arteritis-gita-100635876","NCT07558382","Global Initiative on Takayasu Arteritis (GITA)","Takayasu's Arteritis Global Registry","GITA","Inclusion Criteria:\n\n* Each patient must fullfill the ACR 1990 or ACR\u002FEULAR 2021 criteria for Takayasu arteritis.\n* Patients (or legally acceptable representatives of subjects enrolled) have to\n* provide informed and free agreement to participate in the study and to disclose any medical event to the investigator. The parents or legally acceptable representative and the adolescent subject must be willing and able to comply with the study protocol requirements for the duration of the study\n* freely sign written and dated informed consent after being duly informed of the nature, significance, and implications of the study;\n* be informed that the patient enrolled may withdraw consent at any time without prejudice to future medical care.\n\nExclusion Criteria:\n\nPatients must be excluded from the study when the following criteria are observed:\n\n* The patient does not full-fill the ACR 1990 or ACR\u002FEULAR 2021 criteria for Takayasu arteritis\n* informed consent\u002Fassent is not provided and signed",{"count":510,"type":22},1000,"10 Years","Takayasu's Arteritis Global Registry aims to bring a large group of patients from different parts of the world to analyse and compare the patients' demographic, clinical, laboratory, radiological and prognostic features with outcomes, approaches to diagnosis, assessment, management and therapeutic interventions in different centers. The present project provides for both a retrospective and a prospective longitudinal study. The study is designed as retrospective for patients already diagnosed with TAK and treated with available treatments. Also, the study is designed as prospective for patients diagnosed with TAK after the initiation of the Registry or the adhesion to the project. This is thought as a multicentre, international study addressed to all Centers that will want to contribute to the present project. The study is non-interventional: demographic, clinical and therapeutic data required over time are collected with the routine diagnostic, clinical and therapeutic procedures usually carried out for the optimal management of patients and according with good clinical practice.",[514,515],"Takayasu Arteritis (TAK)","Takayasu's Arteritis",[517,518,519,520],"Takayasu's arteritis","prognosis","Registry","follow-up","2026-04-23",{"date":523,"type":46},"2026-04-30",{"date":525,"type":46},"2025-08-05",{"date":527,"type":22},"2035-08",{"name":52,"class":53},2,{"id":531,"slug":532,"hasResults":12,"nctId":533,"briefTitle":534,"officialTitle":535,"acronym":4,"eligibilityCriteria":536,"healthyVolunteers":92,"sex":537,"minAge":538,"maxAge":4,"enrollmentInfo":539,"targetDuration":4,"studyType":96,"phases":541,"briefSummary":542,"conditions":543,"keywords":4,"overallStatus":147,"whyStopped":4,"lastUpdateSubmitDate":547,"lastUpdatePostDateStruct":548,"startDateStruct":549,"completionDateStruct":550,"leadSponsor":551,"locationsCount":4},"100635504","the-effect-of-a-breathing-and-progressive-muscle-relaxation-program-100635504","NCT07553546","THE EFFECT OF A BREATHING AND PROGRESSIVE MUSCLE RELAXATION PROGRAM","THE EFFECT OF A BREATHING AND PROGRESSIVE MUSCLE RELAXATION PROGRAM ON SLEEP QUALITY AND PSYCHOLOGICAL WELL_BEING IN UNIVERSITY ATHLETES: A NON- RANDOMIZED CONTROLLED INTERVENTION STUDY","Inclusion Criteria:\n\n* Being between the ages of 18 and 24\n* Being male\n* Currently actively participating in an American football team\n* Volunteering to participate in the study\n\nExclusion Criteria:\n\n* Use of antiepileptic, antipsychotic, antidepressant, hormonal, or hypnotic medications Not volunteering to participate in the study","MALE","18 Months",{"count":540,"type":22},60,[98],"This non-randomized controlled study evaluates a 10-week breathing and myofascial release program in university athletes. The intervention group receives structured training, while the control group receives only an informational brochure.",[544,545,546],"Breathing Exercises","PROGRESSIVE MUSCLE RELAXATION EXERCISES","Psychological Well-being","2026-04-20",{"date":468,"type":46},{"date":495,"type":22},{"date":151,"type":22},{"name":52,"class":53},{"id":553,"slug":554,"hasResults":12,"nctId":555,"briefTitle":556,"officialTitle":556,"acronym":4,"eligibilityCriteria":557,"healthyVolunteers":12,"sex":17,"minAge":61,"maxAge":62,"enrollmentInfo":558,"targetDuration":4,"studyType":96,"phases":560,"briefSummary":561,"conditions":562,"keywords":564,"overallStatus":147,"whyStopped":4,"lastUpdateSubmitDate":569,"lastUpdatePostDateStruct":570,"startDateStruct":572,"completionDateStruct":574,"leadSponsor":576,"locationsCount":4},"100632123","comparison-of-single--and-double-level-radiofrequency-ablation-for-chronic-coccydynia-100632123","NCT07509593","Comparison of Single- and Double-Level Radiofrequency Ablation for Chronic Coccydynia","Inclusion Criteria:\n\n* Patients with coccygeal pain lasting longer than 2 months\n* Patients who experienced significant pain relief (≥50% reduction) after a ganglion impar block performed within the last 6 months, but whose pain has subsequently recurred\n* Patients who provide informed consent to participate in the study\n\nExclusion Criteria:\n\n* Acute coccydynia (pain duration less than 2 months)\n* Patients who did not achieve significant benefit (\\\u003C50% pain reduction) from prior ganglion impar block\n* Patients with severe neurological or psychiatric disorders that impair communication or ability to follow instructions",{"count":559,"type":22},50,[98],"This study aims to compare two commonly used radiofrequency ablation (RFA) techniques for the treatment of chronic tailbone (coccyx) pain, also known as coccydynia. Chronic coccydynia can significantly impair daily activities and reduce quality of life, particularly in patients who do not respond adequately to conservative treatments. Participants in this study will be randomly assigned to receive either a single-level or double-level radiofrequency ablation (RFA) procedure targeting the coccygeal nerve pathways. These procedures are minimally invasive and are routinely performed in pain management practice. The primary objective of the study is to determine which technique provides superior pain relief and functional improvement. Patients will be followed for up to two months after the procedure, and pain intensity and quality of life will be evaluated using validated outcome measures. The results of this study may help optimize interventional treatment strategies for patients suffering from chronic coccydynia.",[563],"Chronic Coccydynia",[565,566,567,568],"Chronic coccydynia","Ganglion impar","Radiofrequency ablation","Interventional pain management","2026-04-18",{"date":571,"type":46},"2026-04-22",{"date":573,"type":22},"2026-05",{"date":575,"type":22},"2027-11",{"name":52,"class":53},{"id":578,"slug":579,"hasResults":12,"nctId":580,"briefTitle":581,"officialTitle":582,"acronym":583,"eligibilityCriteria":584,"healthyVolunteers":12,"sex":17,"minAge":585,"maxAge":61,"enrollmentInfo":586,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":588,"conditions":589,"keywords":594,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":600,"lastUpdatePostDateStruct":601,"startDateStruct":603,"completionDateStruct":605,"leadSponsor":606,"locationsCount":54},"100609124","turkish-adaptation-of-a-sleep-screening-tool-for-pediatric-complex-chronic-conditions-100609124","NCT07210476","Turkish Adaptation of a Sleep Screening Tool for Pediatric Complex Chronic Conditions","Turkish Adaptation and Psychometric Evaluation of the Sleep Screening Tool for Children and Adolescents With Complex Chronic Conditions","SCAC","Inclusion Criteria:\n\nAge 1 month to 18 years At least one complex chronic condition (per 2014 CCC classification) Admission to a pediatric intensive care unit (PICU) Parents willing to participate Parents literate in Turkish\n\nExclusion Criteria:\n\nParents with insufficient Turkish language proficiency to complete study materials","1 Month",{"count":587,"type":22},330,"This study aims to adapt the Sleep Screening Scale for Children and Adolescents with Complex Chronic Conditions (SCAC) into Turkish and test its reliability and validity for this population. Children and adolescents with complex chronic conditions (CCC) often have ongoing and multiple health problems. These children often face a high risk of sleep problems, but there are no screening tools in Turkish designed specifically for them.\n\nThe main goal is to confirm that the Turkish version of the SCAC is accurate and reliable. The study will also look at how common different types of sleep problems are in children with CCC, and how these problems are related to factors such as diagnosis, age, sex, and other medical conditions.\n\nAnother goal is to compare children's sleep at home with their sleep during a stay in the pediatric intensive care unit (PICU). The study will also examine how environmental factors (such as light and noise) and medical factors (such as pain, medications, and devices) affect sleep in the hospital. After discharge, sleep recovery will be followed for up to 3 months using sleep diaries and actigraphy (a wearable device that measures movement during sleep).",[590,591,592,593],"Chronic Conditions","Pediatric Intensive Care","Sleep Disorder (Disorder)","Sleep",[595,596,597,598,599],"sleep","sleep disorder","child","chronic disease","actigraphy","2026-04-16",{"date":602,"type":46},"2026-04-17",{"date":604,"type":46},"2026-03-12",{"date":50,"type":22},{"name":52,"class":53},{"id":608,"slug":609,"hasResults":12,"nctId":610,"briefTitle":611,"officialTitle":612,"acronym":613,"eligibilityCriteria":614,"healthyVolunteers":92,"sex":183,"minAge":370,"maxAge":4,"enrollmentInfo":615,"targetDuration":4,"studyType":96,"phases":617,"briefSummary":618,"conditions":619,"keywords":625,"overallStatus":147,"whyStopped":4,"lastUpdateSubmitDate":628,"lastUpdatePostDateStruct":629,"startDateStruct":631,"completionDateStruct":632,"leadSponsor":634,"locationsCount":529},"100634605","breast-and-cervical-cancer-awareness-training-in-visually-impaired-women-100634605","NCT07541859","Breast and Cervical Cancer Awareness Training in Visually Impaired Women","The Effect of Awareness Education on Breast and Cervical Cancer Screening Among Visually Impaired Women","GORSEM","Eligibility Criteria\n\nInclusion Criteria:\n\n* Women with only a visual impairment (congenital or acquired)\n* Able to communicate, speak, and understand Turkish\n* Voluntarily agree to participate in the study\n* Over the age of 40\n* Have had previous sexual intercourse (Pap smear screening requires sexual activity)\n\nExclusion Criteria:\n\n* Diagnosed with breast or cervical cancer\n* Under the age of 40\n* Have not had sexual intercourse before\n* Have undergone screening for at least one of these two cancer types (breast or cervical) within the last year\n\nAccording to the Turkish Ministry of Health, General Directorate of Public Health, in current screenings conducted in our country, within the breast cancer screening program for women, mammography is recommended every two years for women aged 40-69, and within the cervical cancer screening program, Pap smear and HPV-DNA tests are recommended every five years for women aged 30-65. Since women will be referred by the researchers to KETEM centers after training to undergo mammography and Pap smear screening tests, visually impaired women over the age of 40 who have previously had sexual intercourse will be included in the study, as these two screening tests are performed in this common age group and Pap smear screening requires being sexually active.",{"count":616,"type":22},74,[98],"This quasi-experimental study aims to determine whether a breast and cervical cancer awareness training program can increase participation in cancer screening among women with visual impairments. The study also aims to identify barriers to screening and improve knowledge about cancer risk factors and screening methods. The main questions this study will address are:\n\n* Does the training increase the rate at which women with visual impairments attend cancer screening appointments?\n* Does the training improve participants' knowledge about breast and cervical cancer?\n\nParticipants will:\n\n* Receive training on breast and cervical cancer risk factors and screening methods.\n* Learn how to apply to the Cancer Early Diagnosis, Screening, and Training Center.\n* Be encouraged to attend cancer screening during the study period.\n* Have knowledge and screening status assessed before the training, immediately after, and three months later.",[620,621,622,623,624],"Persons With Visual Disabilities","Breast Neoplasms","Uterine Cervical Neoplasms","Awareness","Early Detection of Cancer",[626,627,622,621],"Cancer Screening","Visual Impairment Awareness","2026-04-14",{"date":630,"type":46},"2026-04-21",{"date":260,"type":22},{"date":633,"type":22},"2026-12",{"name":52,"class":53},{"id":636,"slug":637,"hasResults":12,"nctId":638,"briefTitle":639,"officialTitle":640,"acronym":4,"eligibilityCriteria":641,"healthyVolunteers":12,"sex":17,"minAge":61,"maxAge":4,"enrollmentInfo":642,"targetDuration":4,"studyType":96,"phases":644,"briefSummary":645,"conditions":646,"keywords":647,"overallStatus":147,"whyStopped":4,"lastUpdateSubmitDate":651,"lastUpdatePostDateStruct":652,"startDateStruct":653,"completionDateStruct":654,"leadSponsor":656,"locationsCount":54},"100633980","the-effects-of-an-augmented-reality-based-mirror-therapy-system-in-patients-with-stroke-100633980","NCT07533734","The Effects of an Augmented Reality-Based Mirror Therapy System in Patients With Stroke","The Effect of an Augmented Reality-Based Mirror Therapy System on Upper Extremity Motor Recovery and Functional Activity Level in Stroke Patients","Inclusion Criteria:\n\n* First-ever unilateral stroke diagnosed by a specialist physician,\n* Presence of post-stroke hemiplegia,\n* Age ≥ 18 years,\n* Time since stroke between 3 and 12 months,\n* Score ≥ 24 on the Standardized Mini-Mental State Examination,\n* Upper extremity motor score ≤ 22 on the Fugl-Meyer Assessment.\n\nExclusion Criteria:\n\n* Inability to sit independently in a supported chair,\n* Insufficient communication ability due to aphasia,\n* Presence of structural and\u002For acquired impairments limiting active movement of the unaffected upper limb,\n* Presence of visual or visual-perceptual impairments,\n* Presence of unilateral neglect,\n* Presence of neurological, psychiatric, cognitive, or oncological disorders other than stroke.",{"count":643,"type":22},30,[98],"Objective The aim of this study is to investigate the effects of an augmented reality-based mirror therapy system (MirrARm), developed using sensor-based tracking and visual feedback principles, on upper extremity motor recovery and functional activity levels in patients with stroke.\n\nResearch Questions\n\nThis study seeks to address the following questions:\n\nDoes the MirrARm system improve upper extremity motor recovery and functional activity levels in patients with stroke?\n\nAre the effects of the MirrARm system on upper extremity motor recovery and functional activity levels greater than those of conventional mirror therapy in patients with stroke?\n\nStudy Design and Comparison The MirrARm system will be compared with conventional mirror therapy to evaluate its effectiveness in patients with stroke.\n\nParticipants and Procedures Participants will take part in a treatment program administered three days per week for a total duration of eight weeks. Outcome measures will be assessed at baseline (Week 0), at mid-intervention (Week 4), and at the end of the intervention period (Week 8).",[165],[648,649,650],"Augmented Reality","Mirror Movement Therapy","Stroke Rehabilitation","2026-04-09",{"date":600,"type":46},{"date":202,"type":22},{"date":655,"type":22},"2027-08-01",{"name":52,"class":53},{"id":658,"slug":659,"hasResults":12,"nctId":660,"briefTitle":661,"officialTitle":662,"acronym":4,"eligibilityCriteria":663,"healthyVolunteers":92,"sex":17,"minAge":61,"maxAge":4,"enrollmentInfo":664,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":666,"conditions":667,"keywords":671,"overallStatus":147,"whyStopped":4,"lastUpdateSubmitDate":470,"lastUpdatePostDateStruct":674,"startDateStruct":676,"completionDateStruct":677,"leadSponsor":678,"locationsCount":4},"100629866","effect-of-interdental-spacing-and-crown-width-discrepancy-on-smile-esthetics-in-primary-dentition-100629866","NCT07480239","Effect of Interdental Spacing and Crown Width Discrepancy on Smile Esthetics in Primary Dentition","The Impact of Interdental Spacing and Crown Width Discrepancy in Primary Dentition on the Perception of Smile Esthetics","Inclusion Criteria:\n\n* For photographic records (two children):\n* Children without any systemic disease\n* Children in the primary dentition stage\n* Children able to cooperate during the photographic procedure\n* Children whose parents or legal guardians have provided written informed consent for participation and for the use of smile photographs\n* One child presenting physiologic interdental spacing\n* One child presenting no physiologic interdental spacing\n\nFor esthetic perception evaluation:\n\n* Third-, fourth-, or fifth-year dental students\n* Parents presenting to the Department of Pediatric Dentistry for their children's routine dental treatment\n* Individuals who voluntarily agree to participate and provide informed consent\n\nExclusion Criteria:\n\n* Photographs that do not comply with the standardized photography protocol defined in the study\n* Multiple photographs taken of the same teeth or the same tooth surfaces\n* Out-of-focus or blurred images\n* Images that are overexposed, underexposed, or taken under inadequate lighting conditions\n* Photographs with saliva contamination or other artifacts affecting image quality\n* Participants who do not complete the evaluation of all images",{"count":665,"type":22},234,"This cross-sectional study aims to evaluate how interdental spacing and crown width discrepancies in primary dentition influence the perception of smile esthetics. Standardized smile photographs obtained from children with physiologic spacing patterns will be digitally modified to create different dental scenarios, including variations in interdental spacing, midline deviation, and crown width discrepancies. The images will be presented to adult participants, including dental students and parents, who will evaluate the esthetic appearance of each smile using a visual analog scale (VAS). The study seeks to determine how different spacing patterns and tooth size discrepancies affect the perception of smile esthetics in primary dentition.",[668,669,670],"Smile Esthetics","Interdental Spacing","Esthetic Perception",[672,673,669],"aesthetics","primary dentition",{"date":675,"type":46},"2026-04-07",{"date":444,"type":22},{"date":260,"type":22},{"name":52,"class":53},{"id":680,"slug":681,"hasResults":12,"nctId":682,"briefTitle":683,"officialTitle":684,"acronym":4,"eligibilityCriteria":685,"healthyVolunteers":12,"sex":17,"minAge":61,"maxAge":4,"enrollmentInfo":686,"targetDuration":4,"studyType":96,"phases":688,"briefSummary":689,"conditions":690,"keywords":693,"overallStatus":42,"whyStopped":4,"lastUpdateSubmitDate":695,"lastUpdatePostDateStruct":696,"startDateStruct":698,"completionDateStruct":700,"leadSponsor":701,"locationsCount":54},"100631521","physiotherapist-supervised-online-exercise-in-remote-white-collar-workers-100631521","NCT07501767","Physiotherapist-Supervised Online Exercise in Remote White-Collar Workers","Effect of a Physiotherapist-Supervised Online Exercise Program on Pain and Functional Performance in Remote White-Collar Workers","Inclusion Criteria:\n\n* White-collar individuals who have been working remotely for at least 3 months\n* Aged 18 years or older\n* Having low back pain and\u002For neck pain related to the remote working process, or reporting a perceived postural disorder\n* Having a sedentary lifestyle\n\nExclusion Criteria:\n\n* History of chronic disease\n* Presence of a neurological or psychiatric disorder\n* Visual or hearing impairment\n* Inability to cooperate with the study procedures",{"count":687,"type":22},33,[98],"This study evaluates the effects of a physiotherapist-guided online exercise program on pain and functional performance in remote white-collar workers. It is designed as a prospective single-arm study to provide preliminary evidence on the clinical effectiveness of the intervention.",[691,692],"Pain","Functional Performance",[694],"Remote-Working White-Collar Individuals","2026-03-30",{"date":697,"type":46},"2026-04-03",{"date":699,"type":22},"2026-03-17",{"date":573,"type":22},{"name":52,"class":53},""]