[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Maryam Oskoui, MD, MSc, FRCPC, FAAN\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":48},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100546544","a-registry-based-randomized-controlled-trial-of-an-upper-limb-exergaming-intervention-for-children-and-adolescents-with-spinal-muscular-atrophy-100546544",false,"NCT06396325","A Registry Based Randomized-Controlled Trial of an Upper Limb Exergaming Intervention for Children and Adolescents With Spinal Muscular Atrophy","A Registry-Based Parallel Group Randomized-Controlled Trial of an Upper Limb Exergaming Intervention for Children and Adolescents With Spinal Muscular Atrophy, With an Optional Open-Label Extension","INFORM SMA","Inclusion Criteria:\n\n* Confirmed genetic diagnosis of 5q SMA\n* Age at screening: Aged 8-18 years old\n* Participant is able to stay seated independently without support for at least 10 seconds\n* Participants has a score of at least 2 points in entry item A of the RULM (i.e., \"Can raise 1 or 2 hands to the mouth but cannot raise a 200 g weight in it to the mouth\")\n* Treated with disease-modifying therapy\n* Signed ICF\n\nExclusion Criteria:\n\n* Inability to comply with study procedures according to the site investigator, prior to randomization\n* Severe scoliosis or contractures that would interfere with gameplay or with successful completion of functional assessments, as confirmed by the clinical evaluator\n* Planned orthopedic surgery 6 months prior to or throughout intervention and follow-up period (16 weeks post randomization)\n* Inability to read in English or French","ALL","8 Years","18 Years",{"count":21,"type":22},22,"ESTIMATED","INTERVENTIONAL",[25],"NA","This is a multisite randomized controlled registry-based trial to evaluate the efficacy of an 8-week home-based exergaming intervention as compared to usual care on occupational satisfaction of children and youth (8-18 years old age) with spinal muscular atrophy (SMA).",[28],"Spinal Muscular Atrophy",[30,31,32,33,34],"spinal muscular atrophy","rehabilitation","Exergaming","Pediatrics","Randomized-controlled trial","RECRUITING","2025-07-03",{"date":38,"type":39},"2025-07-08","ACTUAL",{"date":41,"type":39},"2024-11-01",{"date":43,"type":22},"2027-12-31",{"name":45,"class":46},"Maryam Oskoui, MD, MSc, FRCPC, FAAN","OTHER",5,""]