[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Max Nieuwdorp\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":42},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":5},"100554726","phase-1-effect-of-4-weeks-of-oral-d-piger-on-safety-pharmacokinetics-and-ethanol-metabolism-in-overweight-individuals-2023-100554726",false,"NCT06502834","Effect of 4 Weeks of Oral D. Piger on Safety, Pharmacokinetics and Ethanol Metabolism in Overweight Individuals (2023)","PIGER","Inclusion:\n\nMale or (postmenopausal) females\n\n* Increased waist circumference (\\>102 cm men, 88\\>cm women)\n* Insulin resistance (HOMA\\>2.5)\n* 18-70 years\n\nExclusion Criteria:\n\n* Use of systemic medication (except for paracetamol), including antibiotics and pro-\u002Fprebiotics in the past three months or during the study period.\n* A history of a cardiovascular event\n* A history of cholecystectomy\n* Overt untreated gastrointestinal disease or abnormal bowel habits\n* Liver enzymes\\>2.5 fold higher than the upper limit of normal range\n* Smoking\n* Alcohol abuse","ALL","18 Years","70 Years",{"count":20,"type":21},20,"ESTIMATED","INTERVENTIONAL",[24],"PHASE1","The goal of the study is to determine the effect of supplementation of the d piger strain on intestinal ethanol production in individuals with overweight.\n\nThe investigators will perform a randomized trial in 2x10 participants to measure effects on ethanol in blood, and perform fecal analyses.",[27,28,29],"Obesity","Metabolic Syndrome","Steatosis of Liver","RECRUITING","2024-07-15",{"date":33,"type":34},"2024-07-16","ACTUAL",{"date":36,"type":34},"2024-05-01",{"date":38,"type":21},"2024-12-01",{"name":40,"class":41},"Max Nieuwdorp","OTHER",""]