[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Medasense Biometrics Ltd\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":45},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":28,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":5},"100640030","impact-of-nol---nociception-level-index-intraoperative-monitoring-on-perioperative-outcomes-in-spine-surgery---a-quality-improvement-pilot-100640030",false,"NCT07608276","Impact of NOL - Nociception Level Index Intraoperative Monitoring on Perioperative Outcomes in Spine Surgery - a Quality Improvement Pilot","Inclusion Criteria:\n\n* Age \\> 18 years old.\n* ASA I-III\n* Elective spine surgery (laminectomy, spinal fusion, and disc replacement) under general anesthesia.\n* Opioid tolerant and patients with documented chronic pain may be included\n* Patient able to provide informed consent\n\nExclusion Criteria:\n\n* • Use of any type of anesthesia other than general anesthesia (neuraxial, epidural analgesia or local regional anesthesia)\n\n  * Use of intraoperative methadone\n  * Non-sinus heart rate\n  * Pregnancy\u002Flactation\n  * Chronic use of psychoactive drugs within 90 days prior to surgery\n  * Patients currently using IV opioids (IV drug abuse)\n  * Allergy or intolerance to any of the study anesthesia related drugs\n  * History of severe cardiac arrhythmias within the last 12 months\n  * Surgeries less than 1.5 hours (from incision to extubation)","ALL","18 Years",{"count":18,"type":19},100,"ESTIMATED","INTERVENTIONAL",[22],"NA","The objective of this study is to evaluate the clinical impact of the NOL nociception level index monitoring on intraoperative and post operative patient outcomes and institutional metrics when used to guide intraoperative analgesia dosing in patients undergoing spine surgery under general anesthesia when compared to a case controlled retrospective cohort.",[25,26,27],"Spine Surgery","Pain After Surgery","Anesthesia , Analgesia",[29,30,31,32],"nociception","pain","NOL nociception level index","quality improvement","NOT_YET_RECRUITING","2026-05-20",{"date":36,"type":37},"2026-05-27","ACTUAL",{"date":39,"type":19},"2026-05",{"date":41,"type":19},"2027-03",{"name":43,"class":44},"Medasense Biometrics Ltd","OTHER",""]