[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Medipol University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":684},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,66,0,25,[9,52,81,103,123,158,175,206,230,253,286,313,344,371,407,442,471,489,518,546,571,592,620,641,659],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":15,"acronym":4,"eligibilityCriteria":16,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":33,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":51},"100644753","time-restricted-eating-after-bariatric-surgery-100644753",false,"NCT07672821","Time-Restricted Eating After Bariatric Surgery","Comparison of Time-Restricted Intermittent Fasting Diet in Individuals With and Without Bariatric Surgery","Inclusion Criteria:\n\n* Adults aged 18-65 years with obesity who have not undergone bariatric surgery\n* Adults aged 18-65 years with obesity who have undergone bariatric surgery and experienced insufficient weight loss (IWL) within 18 months post-surgery, -defined as %EWL \\\u003C50% at 18 months\n* Adults aged 18-65 years with obesity who have undergone bariatric surgery and experienced weight regain (WR), defined as \\>25% increase in %EWL from the lowest recorded weight\n\nExclusion Criteria:\n\n* Pregnant or breastfeeding individuals\n* Acute illness, active infection, or comorbid conditions limiting treatment efficacy and safety, including: cancer, type 1 diabetes, renal or hepatic failure, recent stroke or myocardial infarction, nephrolithiasis, drug or alcohol abuse, eating disorders, severe depression or other psychiatric disorders, inflammatory bowel disease (IBD), neoplasia, arrhythmic heart disease, heart failure, respiratory failure, or corticosteroid therapy\n* Professional athletes","ALL","18 Years","65 Years",{"count":21,"type":22},40,"ESTIMATED","INTERVENTIONAL",[25],"NA","This study aims to compare the effects of time-restricted eating (TRE, 16\u002F8) in adults with obesity who have and have not undergone bariatric surgery (BS). The study will include adults aged 18-65 years: those with obesity who have not undergone BS, and those who have experienced insufficient weight loss (IWL) or weight regain (WR) following BS. Both groups will follow a 16:8 time-restricted eating protocol for 6 weeks, with an 8-hour eating window recommended between 10:00 AM and 6:00 PM, though participants may adjust to other 16-hour fasting windows. Participants will be evaluated before and after the intervention in terms of anthropometric measurements, biochemical parameters, and dietary habits. The study is being conducted at a private hospital in Bursa, Turkey, and is planned to be completed with a total of 40 participants (20 per group).",[28,29,30,31,32],"Obesity & Overweight","Bariatric Surgery","Weight Regain","Weight Regain Post Bariatric Surgery","Time Restricted Feeding",[34,35,29,36,30,37,38],"Time-Restricted Eating","Intermittent Fasting","Obesity","Anthropometric Measurements","Nutritional Assessment","RECRUITING","2026-06-26",{"date":42,"type":43},"2026-06-29","ACTUAL",{"date":45,"type":43},"2025-07-12",{"date":47,"type":22},"2026-07-12",{"name":49,"class":50},"Medipol University","OTHER",2,{"id":53,"slug":54,"hasResults":12,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":4,"eligibilityCriteria":58,"healthyVolunteers":59,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":60,"targetDuration":4,"studyType":23,"phases":62,"briefSummary":63,"conditions":64,"keywords":68,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":75,"completionDateStruct":77,"leadSponsor":79,"locationsCount":80},"100644596","antibacterial-efficacy-of-bioceramic-and-calcium-hydroxide-intracanal-medicaments-100644596","NCT07671326","Antibacterial Efficacy of Bioceramic and Calcium Hydroxide Intracanal Medicaments","Antibacterial Efficacy of Bioceramic and Calcium Hydroxide-Based Intracanal Medicaments in Endodontic Treatment","Inclusion Criteria:\n\n* Patients aged between 18 and 65 years\n* Being systemically healthy (ASA I or ASA II)\n* Mandibular molar teeth with a radiographically detectable radiolucent lesion in the periapical region\n* Willingness of the volunteer or their legal representative to participate in the study by signing the Informed Consent Form\n\nExclusion Criteria:\n\n* Patients who have received antibiotics or corticosteroids within the last 3 months\n* Patients with systemic diseases\n* Teeth that cannot be properly isolated with a rubber dam\n* Teeth with periodontal pockets \\>4 mm and teeth with crown\u002Froot fractures\n* Individuals who are undergoing or planning to start orthodontic treatment during the study period\n* Pregnant or breastfeeding individuals",true,{"count":61,"type":22},24,[25],"This study evaluates the antibacterial effectiveness of two different intracanal medicaments, Bio-C Temp and UltraCal XS , in mandibular molar teeth with chronic apical periodontitis. Intracanal bacterial load is assessed before and after root canal preparation, after intracanal medicament removal, and after final irrigation using droplet digital PCR.",[65,66,67],"Periapical Periodontitis","Root Canal Infection","Intracanal Medicaments",[69,70,71,72],"intracanal medicament","bioceramic medicament","ultrasonic activation","ddPCR","2026-06-25",{"date":42,"type":43},{"date":76,"type":43},"2025-10-15",{"date":78,"type":22},"2026-12",{"name":49,"class":50},1,{"id":82,"slug":83,"hasResults":12,"nctId":84,"briefTitle":85,"officialTitle":86,"acronym":4,"eligibilityCriteria":87,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":88,"targetDuration":4,"studyType":23,"phases":90,"briefSummary":91,"conditions":92,"keywords":4,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":95,"lastUpdatePostDateStruct":96,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":80},"100644167","task-oriented-rehabilitation-after-rotator-cuff-surgery-100644167","NCT07665541","TASK-ORIENTED REHABILITATION AFTER ROTATOR CUFF SURGERY","THE EFFECT OF TASK-ORIENTED OCCUPATIONAL THERAPY INTERVENTION ON ACTIVITY PARTICIPATION AFTER ROTATOR CUFF SURGERY: PRE- AND POST-INTERVENTION EVALUATION","Inclusion Criteria:\n\n* Individuals aged 18 years and older\n* Individuals who have undergone rotator cuff surgery\n* Medically stable and cleared for participation in a rehabilitation program\n* Ability to understand and follow instructions\n* Voluntary agreement to participate in the study\n\nExclusion Criteria:\n\n* \\- Presence of severe neurological disorders affecting upper extremity function\n* Severe cognitive impairment limiting participation\n* Additional musculoskeletal conditions affecting the upper extremity\n* Postoperative complications that may interfere with rehabilitation\n* Participation in another rehabilitation program during the study period",{"count":89,"type":22},30,[25],"Rotator cuff tears negatively affect shoulder stability, range of motion, and performance in daily activities. Postoperative rehabilitation is essential for improving functional recovery and quality of life; however, conventional approaches may not directly target meaningful activity performance.\n\nTask-oriented occupational therapy is a client-centered approach focusing on meaningful and goal-directed activities to enhance functional independence. This randomized controlled trial aims to investigate the effect of task-oriented occupational therapy on activity participation, occupational performance, satisfaction, and functional recovery after rotator cuff surgery.\n\nA total of 30 participants will be randomly assigned to either a task-oriented occupational therapy group or a conventional rehabilitation group. The intervention will be conducted twice weekly for 10 weeks, with 40-minute sessions based on individually prioritized activities identified using the Canadian Occupational Performance Measure. Outcomes will include occupational performance and satisfaction, goal attainment, shoulder function, quality of life, and patient satisfaction.",[93],"Rotator Cuff Tear Repair","NOT_YET_RECRUITING","2026-06-22",{"date":97,"type":43},"2026-06-24",{"date":99,"type":22},"2026-06-30",{"date":101,"type":22},"2026-10-19",{"name":49,"class":50},{"id":104,"slug":105,"hasResults":12,"nctId":106,"briefTitle":107,"officialTitle":108,"acronym":109,"eligibilityCriteria":110,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":111,"targetDuration":4,"studyType":113,"phases":4,"briefSummary":114,"conditions":115,"keywords":4,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":117,"lastUpdatePostDateStruct":118,"startDateStruct":119,"completionDateStruct":120,"leadSponsor":122,"locationsCount":4},"100644074","preoperative-central-sensitization-and-postoperative-outcomes-after-arthroscopic-rotator-cuff-repair-100644074","NCT07667257","Preoperative Central Sensitization and Postoperative Outcomes After Arthroscopic Rotator Cuff Repair","Effect of Central Sensitization on Postoperative Clinical Outcomes in Patients Undergoing Arthroscopic Rotator Cuff Repair","ARCS","Inclusion Criteria:\n\n* Inclusion Criteria:\n* Age between 18 and 65 years\n* Diagnosis of rotator cuff tear confirmed by clinical examination and magnetic resonance imaging (MRI)\n* Scheduled to undergo arthroscopic rotator cuff repair\n* Ability to understand and complete study questionnaires\n* Willingness to participate and provide informed consent\n\nExclusion Criteria:\n\n* Previous surgery on the affected shoulder.\n* Concomitant shoulder disorders requiring additional surgical procedures (e.g., fracture, instability, advanced glenohumeral osteoarthritis).\n* History of inflammatory rheumatic disease, active infection, or malignancy affecting the shoulder.\n* Neurological disorders that may influence pain perception or upper extremity function.\n* Severe psychiatric illness or cognitive impairment preventing completion of the questionnaires.\n* Pregnancy.\n* Inability or unwillingness to provide written informed consent.\n* Inability to attend the postoperative 3-month follow-up evaluation.",{"count":112,"type":22},50,"OBSERVATIONAL","This prospective observational study aims to investigate the effect of preoperative central sensitization on postoperative clinical outcomes in patients undergoing arthroscopic rotator cuff repair. Central sensitization, characterized by an increased responsiveness of the central nervous system to pain stimuli, has been associated with persistent pain and poor functional recovery in various musculoskeletal disorders. However, its impact on outcomes following arthroscopic rotator cuff repair has not been fully elucidated.\n\nAdult patients diagnosed with a rotator cuff tear by clinical examination and magnetic resonance imaging (MRI) and scheduled for arthroscopic repair will be enrolled. Preoperative central sensitization will be assessed using the Central Sensitization Inventory (CSI), while pain intensity and shoulder function will be evaluated using the Visual Analog Scale (VAS) and the Shoulder Pain and Disability Index (SPADI), respectively. Clinical assessments will be performed preoperatively and at postoperative 3 months. The study aims to determine whether preoperative central sensitization is associated with postoperative pain and functional recovery after arthroscopic rotator cuff repair.",[116],"Rotator Cuff Tear","2026-06-20",{"date":73,"type":43},{"date":99,"type":22},{"date":121,"type":22},"2026-12-30",{"name":49,"class":50},{"id":124,"slug":125,"hasResults":12,"nctId":126,"briefTitle":127,"officialTitle":128,"acronym":129,"eligibilityCriteria":130,"healthyVolunteers":12,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":131,"targetDuration":4,"studyType":113,"phases":4,"briefSummary":132,"conditions":133,"keywords":142,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":149,"lastUpdatePostDateStruct":150,"startDateStruct":152,"completionDateStruct":154,"leadSponsor":156,"locationsCount":157},"100625308","mechanical-insufflation-exsufflation-in-critically-ill-patients-100625308","NCT07420946","Mechanical Insufflation-Exsufflation in Critically Ill Patients","Mechanical Insufflation-Exsufflation in Critically Ill Patients: An International DELphi Consensus (DELMI-E)","DELMI-E","Inclusion Criteria:\n\n* Healthcare professionals with documented clinical experience in critical care medicine, pulmonology, anesthesiology, respiratory therapy, or physiotherapy with involvement in airway clearance strategies.\n* Demonstrated experience or recognized expertise in the clinical use of MI-E, either in critically ill patients or in patients with complex respiratory conditions.\n* A minimum of 5 years of clinical experience in their respective field, or a proven academic or clinical contribution related to MI-E.\n* Willingness to participate in multiple Delphi rounds and to provide informed consent.\n* Ability to complete the questionnaires in English.\n\nExclusion Criteria:\n\n* Lack of direct clinical or academic experience related to MI-E or airway clearance techniques.\n* Inability or unwillingness to provide informed consent.\n* Failure to complete the first Delphi round after formal invitation and consent.\n* Withdrawal of consent at any stage of the Delphi process.",{"count":89,"type":22},"Mechanical insufflation-exsufflation (MI-E) is an established airway clearance technique for patients with chronic conditions like neuromuscular diseases. However, its use in critically ill ICU patients remains inconsistent and lacks standardized guidelines. Despite growing research, current practices vary widely in patient selection, treatment protocols, and safety management, with limited high-quality evidence to support clear recommendations. To address this gap, an international, multidisciplinary Delphi consensus study is needed to establish expert-based best practices and feasible guidelines for the safe and effective implementation of MI-E in the intensive care setting.",[134,135,136,137,138,139,140,141],"Airway Clearance","Mechanical Insufflation-exsufflation","Mechanical Insufflation-exsufflation Session ( With Cough Assist)","Delphi Study","Consensus","Critical Illness","Critical Care","Critical Care, Intensive Care",[143,144,145,138,146,147,148],"mechanical insufflation-exsufflation","Airway clearance","Delphi study","Cough assist","MI-E","critical care","2026-06-15",{"date":151,"type":43},"2026-06-17",{"date":153,"type":43},"2026-06-10",{"date":155,"type":22},"2026-12-01",{"name":49,"class":50},4,{"id":159,"slug":160,"hasResults":12,"nctId":161,"briefTitle":162,"officialTitle":163,"acronym":164,"eligibilityCriteria":165,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":166,"targetDuration":4,"studyType":113,"phases":4,"briefSummary":167,"conditions":168,"keywords":4,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":170,"lastUpdatePostDateStruct":171,"startDateStruct":172,"completionDateStruct":173,"leadSponsor":174,"locationsCount":4},"100642010","effect-of-preoperative-kinesiophobia-on-clinical-outcomes-following-arthroscopic-meniscus-surgery-100642010","NCT07654894","Effect of Preoperative Kinesiophobia on Clinical Outcomes Following Arthroscopic Meniscus Surgery","Effect of Preoperative Kinesiophobia on Clinical Success in Patients Undergoing Arthroscopic Surgery for Meniscal Tears","MEN-KIN","Inclusion Criteria:\n\nAdults aged 18 to 65 years. Diagnosis of meniscal tear confirmed by clinical examination and magnetic resonance imaging (MRI).\n\nPatients scheduled to undergo arthroscopic meniscal surgery. Ability to understand and complete the study questionnaires. Willingness to participate and provide written informed consent. Availability for both preoperative assessment and postoperative 3-month follow-up.\n\nExclusion Criteria:\n\nPrevious surgery on the affected knee. Concomitant anterior cruciate ligament (ACL), posterior cruciate ligament (PCL), or collateral ligament injuries requiring surgical treatment.\n\nAdvanced knee osteoarthritis (e.g., Kellgren-Lawrence grade 3 or 4). History of inflammatory rheumatic disease or active joint infection. Neurological disorders affecting lower extremity function or balance. Severe psychiatric disorders or cognitive impairment preventing completion of questionnaires.\n\nPregnancy. Inability or unwillingness to provide written informed consent. Inability to attend the 3-month postoperative follow-up.",{"count":112,"type":22},"Meniscal tears are among the most common knee injuries and frequently require arthroscopic surgical treatment when conservative management fails or mechanical symptoms persist. Although surgical techniques have improved clinical outcomes, postoperative recovery is influenced not only by structural pathology but also by psychological factors. Kinesiophobia, defined as an excessive and debilitating fear of movement due to pain or the expectation of reinjury, may negatively affect rehabilitation adherence, functional recovery, and pain perception.\n\nThis prospective observational study aims to investigate the effect of preoperative kinesiophobia on postoperative clinical outcomes in patients undergoing arthroscopic surgery for meniscal tears. Adult patients diagnosed with a meniscal tear by clinical examination and magnetic resonance imaging and scheduled for arthroscopic surgery will be enrolled. Preoperative demographic and clinical characteristics, pain intensity, functional status, and kinesiophobia levels will be assessed using validated outcome measures. Postoperative evaluations will be performed three months after surgery to determine changes in pain and functional outcomes. The relationship between preoperative kinesiophobia and postoperative clinical success will be analyzed. The findings of this study may help identify patients at risk for suboptimal recovery and support the development of individualized rehabilitation strategies.",[169],"Meniscal Tear","2026-06-12",{"date":151,"type":43},{"date":73,"type":22},{"date":121,"type":22},{"name":49,"class":50},{"id":176,"slug":177,"hasResults":12,"nctId":178,"briefTitle":179,"officialTitle":180,"acronym":4,"eligibilityCriteria":181,"healthyVolunteers":59,"sex":17,"minAge":182,"maxAge":183,"enrollmentInfo":184,"targetDuration":4,"studyType":23,"phases":186,"briefSummary":187,"conditions":188,"keywords":191,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":198,"lastUpdatePostDateStruct":199,"startDateStruct":201,"completionDateStruct":203,"leadSponsor":205,"locationsCount":4},"100643425","effects-of-a-vision-focused-occupational-therapy-program-on-visual-skills-in-primary-school-children-100643425","NCT07635706","EFFECTS OF A VISION-FOCUSED OCCUPATIONAL THERAPY PROGRAM ON VISUAL SKILLS IN PRIMARY SCHOOL CHILDREN","THE EFFECT OF A VISION-FOCUSED OCCUPATIONAL THERAPY PROGRAM ON VISUAL PERCEPTION AND SCHOOL-BASED VISUAL-MOTOR FUNCTIONS IN PRIMARY SCHOOL CHILDREN","Inclusion Criteria:\n\n* Children aged 8 to 10 years\n* Enrollment in 3rd or 4th grade of primary school\n* Ability to understand and follow study instructions\n* Written informed consent obtained from parent or legal guardian\n* Willingness to participate in all assessment and intervention sessions\n\nExclusion Criteria:\n\n* Diagnosed neurological, psychiatric, developmental, or intellectual disorder\n* Uncorrected visual impairment that may affect assessment results\n* Musculoskeletal condition affecting upper extremity function\n* Participation in another structured visual training or rehabilitation program during the study period\n* Inability to complete study assessments or intervention sessions","8 Years","10 Years",{"count":185,"type":22},32,[25],"This randomized controlled trial aims to investigate the effects of a structured visual skills-based occupational therapy program on visual perception and school-based visual-motor functions in typically developing primary school students aged 8-10 years. Participants will be randomly assigned to either an intervention group receiving a 6-week visual skills program or a control group receiving routine school activities and home-based assignments. Outcomes including visual perception, visual-motor performance, convergence ability, and motor proficiency will be assessed before and after the intervention.",[189,190],"Visual Deficiencies","Visual Attention",[192,193,194,195,196,197],"Visual Skills","Visual Perception","Visual-Motor Integration","Oculomotor Training","Occupational Therapy","School-Based Occupational Therapy","2026-06-03",{"date":200,"type":43},"2026-06-09",{"date":202,"type":22},"2026-06-08",{"date":204,"type":22},"2026-07-31",{"name":49,"class":50},{"id":207,"slug":208,"hasResults":12,"nctId":209,"briefTitle":210,"officialTitle":210,"acronym":4,"eligibilityCriteria":211,"healthyVolunteers":12,"sex":17,"minAge":212,"maxAge":19,"enrollmentInfo":213,"targetDuration":4,"studyType":23,"phases":214,"briefSummary":215,"conditions":216,"keywords":218,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":222,"lastUpdatePostDateStruct":223,"startDateStruct":225,"completionDateStruct":227,"leadSponsor":229,"locationsCount":51},"100599942","effectiveness-of-robot-assisted-structured-foot-ankle-sensorimotor-training-in-stroke-patients-100599942","NCT07091045","Effectiveness of Robot-Assisted Structured Foot-Ankle Sensorimotor Training in Stroke Patients","The inclusion criteria are as follows:\n\n1. Age 40-65 years,\n2. Able to understand and follow study instructions,\n3. Able to communicate coherently and oriented in time and place,\n4. Provided written informed consent,\n5. Stroke ≥6 months prior to enrollment (chronic stroke),\n6. Ankle plantarflexor spasticity ≤2 on the Modified Ashworth Scale,\n7. Ankle dorsiflexor strength ≥ grade 2 on the Medical Research Council (MRC) scale,\n8. Passive ankle dorsiflexion to neutral (90°; 0°) without a plantarflexion contracture,\n9. Moderate or mild lower-extremity impairment based on the Fugl-Meyer Assessment-Lower Extremity (FMA-LE) score (21-27 moderate; 28-34 mild\u002Fgood),\n10. Able to sit for at least 1 hour,\n11. Able to walk at least 10 meters with or without an assistive device,\n12. Completed all conventional lower-extremity physical therapy and rehabilitation programs.\n\nThe exclusion criteria are as follows:\n\n1. Cognitive impairment (Mini-Mental State Test score ≤ 24),\n2. Conditions affecting walking or balance (e.g., orthopedic complications, lower extremity amputation, osteoporosis),\n3. Insufficient visual acuity to view a screen (e.g., diplopia),\n4. Severe visual deficits (e.g., hemianopia) or vestibular disorders34,\n5. Sensory deficits such as hemisensory neglect,\n6. Acute musculoskeletal or cardiovascular disorders,\n7. Intrathecal baclofen pump use or botulinum toxin injections within the past 5 months,\n8. Fixed or painful contracture of the paretic ankle,\n9. Uncontrolled systemic diseases (e.g., diabetes, hypertension, debilitating or immunosuppressive diseases),\n10. history of a non-stroke neurological disease\u002Fdisorder that may impair comprehension of instructions,\n11. Concurrent participation in other lower-extremity physical therapy, robotic rehabilitation, or neurological exercise programs.","40 Years",{"count":89,"type":22},[25],"Introduction: Stroke is a leading cause of long-term disability worldwide. Persistent lower-extremity motor and somatosensory impairments after stroke commonly limit walking and balance despite rehabilitation. Virtual reality (VR)-integrated robotic rehabilitation may support structured, goal-directed ankle-foot practice; however, there is limited evidence for ankle-foot-focused sensorimotor protocols. In particular, approaches that combine robot-assisted motor training with a plantar tactile localization task and VR-supported joint position sense (JPS) training to target plantar sensory and proprioceptive function are scarce. Therefore, this study aims to evaluate the effectiveness of a structured, VR-integrated, robot-assisted ankle-foot sensorimotor rehabilitation protocol in individuals with chronic stroke and to examine its effects on clinical and sensorimotor outcomes.\n\nMethods and analysis: This is an assessor-blinded, two-arm, parallel-group randomized controlled trial. Thirty individuals with chronic stroke will be randomized 1:1 to the Robot-assisted Training Group (RTG) or the Manual Training Group (MTG). All participants will receive conventional rehabilitation; in addition, RTG will receive a structured robot-assisted ankle-foot training program integrated with virtual reality and assist-as-needed control, whereas MTG will receive the same structured ankle-foot training protocol delivered manually by a physiotherapist. Interventions will be delivered three times per week for 6 weeks (18 sessions), and total session duration will be time-matched between groups (50-60 min per session). The primary outcome will be the change in walking speed, derived from the 10-Meter Walk Test, from baseline to 6 weeks. Secondary outcomes will include 2-Minute Walk Test distance, ankle range of motion, joint position sense, plantar tactile sensation, muscle tone, motor performance, static and dynamic balance, and stroke-specific quality of life.",[217],"Stroke",[219,220,221],"stroke","rehabilitation medicine","virtual reality","2026-05-24",{"date":224,"type":43},"2026-05-28",{"date":226,"type":43},"2026-03-01",{"date":228,"type":22},"2027-05-15",{"name":49,"class":50},{"id":231,"slug":232,"hasResults":12,"nctId":233,"briefTitle":234,"officialTitle":235,"acronym":4,"eligibilityCriteria":236,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":237,"targetDuration":4,"studyType":23,"phases":239,"briefSummary":240,"conditions":241,"keywords":244,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":246,"lastUpdatePostDateStruct":247,"startDateStruct":249,"completionDateStruct":250,"leadSponsor":252,"locationsCount":80},"100639430","comparison-of-qlb-and-tfp-block-for-postoperative-analgesia-in-laparoscopic-inguinal-hernia-100639430","NCT07604259","Comparison of QLB and TFP Block for Postoperative Analgesia in Laparoscopic Inguinal Hernia","Comparison of the Effects of Ultrasound-Guided Lateral Quadratus Lumborum Block and Transversalis Fascia Plane Block on Postoperative Analgesia in Patients Undergoing Laparoscopic Inguinal Hernia Repair: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Scheduled for elective laparoscopic inguinal hernia repair.\n* American Society of Anesthesiologists (ASA) physical status I, II, or III.\n* Age between 18 and 65 years.\n* Provided written informed consent.\n\nExclusion Criteria:\n\n* History of allergy to local anesthetics.\n* Presence of coagulopathy.\n* Signs of infection at the intended block application site.\n* Body Mass Index (BMI) ≥ 35 kg\u002Fm².\n* History of chronic opioid use.\n* Presence of neurological disease.\n* Refusal to participate in the study.",{"count":238,"type":22},90,[25],"This randomized controlled trial aims to compare the effects of ultrasound-guided lateral Quadratus Lumborum Block (QLB) and Transversalis Fascia Plane (TFP) block on postoperative analgesia in patients undergoing laparoscopic inguinal hernia repair. Ninety patients will be randomly assigned to one of three groups: Group QLB, Group TFP, or Group Control. The primary objective is to compare postoperative pain scores (NRS) at various time points within the first 24 hours. Secondary objectives include evaluating the need for rescue analgesia, total tramadol consumption, and the incidence of opioid-related side effects.",[242,243],"İnguinal Hernia","Post Operative Pain",[245],"Laparoscopic inguinal hernia, Quadratus Lumborum Block, Transversalis Fascia Plane Block, Postoperative analgesia, Regional anesthesia.","2026-05-18",{"date":248,"type":43},"2026-05-22",{"date":153,"type":22},{"date":251,"type":22},"2027-05-10",{"name":49,"class":50},{"id":254,"slug":255,"hasResults":12,"nctId":256,"briefTitle":257,"officialTitle":258,"acronym":259,"eligibilityCriteria":260,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":261,"enrollmentInfo":262,"targetDuration":4,"studyType":23,"phases":263,"briefSummary":264,"conditions":265,"keywords":267,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":278,"lastUpdatePostDateStruct":279,"startDateStruct":281,"completionDateStruct":283,"leadSponsor":285,"locationsCount":80},"100608967","web-based-exercise-program-for-non-specific-low-back-pain-100608967","NCT07208435","Web-Based Exercise Program for Non-Specific Low Back Pain","Effectiveness of Web-Based Exercise Programs in the Management of Non-Specific Low Back Pain: A Randomized Controlled Trial","WEBEX-LBP","Inclusion Criteria:\n\n* Adults aged 18-45 years diagnosed with non-specific low back pain (NSLBP) for 6 weeks to \\\u003C12 months.\n* Self-reported pain intensity ≥3 on a 0-10 Numeric Pain Rating Scale (NPRS).\n* Evidence of functional limitation (Oswestry Disability Index or Roland-Morris Disability Questionnaire).\n* Access to a smartphone, tablet, or computer with internet connectivity.\n* Ability and willingness to participate in telerehabilitation programs.\n\nExclusion Criteria:\n\n* Specific causes of low back pain (herniated disc with radiculopathy, spinal stenosis, spondylolisthesis, fractures, infections, malignancy).\n* Neurological deficits (e.g., severe motor weakness, progressive neurological symptoms).\n* Severe psychiatric or cognitive disorders interfering with participation.\n* History of spinal surgery within the last year.\n* Severe comorbidities contraindicating exercise (e.g., uncontrolled diabetes, cardiovascular disease).\n* Pregnant or planning pregnancy during the study period.\n* Active substance or alcohol abuse.\n* Participation in other structured rehabilitation or physical therapy programs within the last 3 months.","45 Years",{"count":89,"type":22},[25],"This study evaluates the effectiveness of a web application-based exercise program (delivered via Physitrack) for managing non-specific low back pain (NSLBP) compared to traditional home exercise programs. The trial focuses on whether web-based delivery can improve pain, function, quality of life, and adherence, providing evidence for digital rehabilitation as a practical alternative to conventional physiotherapy.",[266],"Non-specific Low Back Pain (NSLBP)",[268,269,270,271,272,273,274,275,276,277],"Non-Specific Low Back Pain","NSLBP","Web-Based Exercise Program","Telerehabilitation","Randomized Controlled Trial","Physiotherapy","Home Exercise Program","Pain Management","Functional Improvement","Quality of Life","2026-05-16",{"date":280,"type":43},"2026-05-19",{"date":282,"type":22},"2026-05",{"date":284,"type":22},"2026-06",{"name":49,"class":50},{"id":287,"slug":288,"hasResults":12,"nctId":289,"briefTitle":290,"officialTitle":291,"acronym":292,"eligibilityCriteria":293,"healthyVolunteers":59,"sex":17,"minAge":294,"maxAge":183,"enrollmentInfo":295,"targetDuration":4,"studyType":113,"phases":4,"briefSummary":297,"conditions":298,"keywords":301,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":306,"lastUpdatePostDateStruct":307,"startDateStruct":308,"completionDateStruct":310,"leadSponsor":312,"locationsCount":80},"100639293","ai-based-video-analysis-for-motor-development-assessment-in-children-100639293","NCT07597356","AI-Based Video Analysis for Motor Development Assessment in Children","Development and Validation of an Artificial Intelligence-Based System for Assessing Motor Development in Children Using Video Analysis","AMD-AI","Inclusion Criteria:\n\n* Children aged between 5 and 10 years\n* No diagnosed neurological, developmental, or orthopedic disorders\n* Ability to follow verbal instructions\n* Informed consent obtained from parents or legal guardians\n* No prior participation in sensory integration therapy or special education programs\n\nExclusion Criteria:\n\n* Diagnosed neurological, developmental, or orthopedic conditions (e.g., autism spectrum disorder, cerebral palsy, epilepsy)\n* Visual or hearing impairments affecting task performance\n* Severe attention or behavioral problems preventing test completion\n* Physical limitations preventing participation in motor tasks","5 Years",{"count":296,"type":22},60,"This is a non-interventional, prospective observational study aimed at developing and validating an artificial intelligence-based system for assessing motor development in children using video analysis. Children aged 5 to 10 years will perform standardized motor tasks, which will be recorded under controlled conditions. The recorded videos will be analyzed using computer vision and deep learning techniques to extract movement patterns.\n\nThe results of the AI-based analysis will be compared with standardized motor assessment scores obtained from the Bruininks-Oseretsky Test of Motor Proficiency, Second Edition - Short Form (BOT-2 SF). Participants will be classified into typical and atypical motor development groups based on BOT-2 scores. The primary objective is to evaluate the classification performance of the AI model. Secondary analyses will examine the relationship between AI predictions and continuous motor performance scores.\n\nThe study is designed to explore whether motor development can be assessed objectively without direct clinical testing, using only short video recordings. The findings may contribute to the development of scalable and accessible digital screening tools for early identification of motor development differences in children.",[299,300],"Motor Development Assessment","Artificial Intelligence-Based Movement Analysis",[302,303,304,305],"Motor Development","Video Analysis","Artificial Intelligence","Deep Learning","2026-05-15",{"date":280,"type":43},{"date":309,"type":43},"2026-01-01",{"date":311,"type":22},"2026-09-01",{"name":49,"class":50},{"id":314,"slug":315,"hasResults":12,"nctId":316,"briefTitle":317,"officialTitle":318,"acronym":4,"eligibilityCriteria":319,"healthyVolunteers":12,"sex":17,"minAge":320,"maxAge":261,"enrollmentInfo":321,"targetDuration":4,"studyType":23,"phases":322,"briefSummary":323,"conditions":324,"keywords":326,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":336,"lastUpdatePostDateStruct":337,"startDateStruct":339,"completionDateStruct":341,"leadSponsor":343,"locationsCount":4},"100614300","device-based-vs-manual-sensory-training-in-low-back-pain-100614300","NCT07277803","Device-Based vs Manual Sensory Training in Low Back Pain","Effects of Device-Based and Manual Sensory Acuity Training on Chronic Low Back Pain: A Three-Arm Randomized Controlled Trial Protocol","Inclusion Criteria:\n\n* Age between 25-45 years\n* No spinal fracture or acute disc herniation\n* Pain duration ≥ 3 months\n* Pain intensity ≥ 4\u002F10\n* Central Sensitization Scale (CSI) score ≥ 40\n* No current psychiatric illness or cognitive impairment\n* No contraindications to exercise\n\nExclusion Criteria:\n\n* Serious spinal pathologies (lumbar stenosis, spondylolisthesis, tumor, infection, metastasis, osteoporotic fracture, severe structural deformities, inflammatory arthritis)\n* Conditions with radicular involvement or neurological deficits (sciatica, nerve root compression)\n* Systemic or neurological diseases (diabetes mellitus, neuromuscular diseases, serious central or peripheral nervous system diseases, epilepsy)\n* Mental disorders\n* Pregnancy\n* Lower extremity injuries\n* Spinal surgery within the last three years\n* Chronic generalized pain syndromes (fibromyalgia, chronic fatigue syndrome)\n* Individuals receiving other treatment for non-specific chronic low back pain during the study period.","25 Years",{"count":5,"type":22},[25],"Chronic low back pain (CLBP) is a leading cause of disability worldwide and affects a large proportion of working-age individuals. Cortical reorganization in CLBP, particularly within the sensorimotor cortex, has been shown to negatively influence sensory acuity and motor control. The neuroplasticity underlying this reorganization may enhance the effectiveness of sensorimotor retraining therapies that involve specific stimulus features targeting somatosensory cortical regions.\n\nThis randomized controlled trial will include three groups: a device-assisted sensory acuity training group, a manual sensory acuity training group, and a control group receiving conventional physiotherapy. In this study, device-assisted sensory acuity training will be delivered using a standardized vibrotactile interface that presents controlled stimuli and records participant responses. The intervention will be structured to target sensory acuity components similar to those addressed in manual training.\n\nAccordingly, the structured training protocol will include:\n\n* localization training to improve detection of stimulus location,\n* orientation discrimination to identify stimulus direction,\n* temporal acuity training to distinguish timing differences between tactile stimuli and\n* graphesthesia training to improve recognition of shapes or letters drawn on the skin through tactile input.\n\nThe primary aim of this study is to evaluate sensory acuity in individuals with CLBP and to determine the effects of a structured manual and technology-based sensory acuity training program, combined with conventional physiotherapy, on pain intensity (VAS), lumbar two-point discrimination, and a composite sensory acuity score.\n\nWe hypothesize that adding manual and technology-based structured sensory acuity training (SAT) program to a conventional physiotherapy regimen including motor control exercises will support central nervous system reorganization, improve sensory profiles, and lead to improvements in pain-related variables, disability, and quality of life.\n\nThrough this structured SAT program, we aim to provide an approach that evaluates and trains multiple dimensions of sensory acuity in CLBP, including localization, orientation, and temporal discrimination.",[325],"Low Back Pain",[327,328,329,330,331,332,333,334,335],"Chronic pain","physiotherapy and rehabilitation","radial\u002Flocal vibration","low back pain","pain treatment","tactile feedback","mobile applications","wearable technologies","embedded system design","2026-05-12",{"date":338,"type":43},"2026-05-13",{"date":340,"type":22},"2026-08-15",{"date":342,"type":22},"2027-12-15",{"name":49,"class":50},{"id":345,"slug":346,"hasResults":12,"nctId":347,"briefTitle":348,"officialTitle":349,"acronym":4,"eligibilityCriteria":350,"healthyVolunteers":12,"sex":351,"minAge":18,"maxAge":320,"enrollmentInfo":352,"targetDuration":4,"studyType":23,"phases":354,"briefSummary":355,"conditions":356,"keywords":358,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":363,"lastUpdatePostDateStruct":364,"startDateStruct":366,"completionDateStruct":368,"leadSponsor":370,"locationsCount":80},"100636572","digital-game-and-simulation-in-midwifery-education-100636572","NCT07567430","Digital Game and Simulation in Midwifery Education","The Effect Of Dıgıtal Game-Based Learnıng On Learnıng Motıvatıon And Attıtude In Preeclampsıa-Eclampsıa Educatıon In Mıdwıfery Students: Comparıson Wıth Sımulatıon And Tradıtıonal Educatıon","Inclusion Criteria:\n\n* Being an undergraduate midwifery student (4th year).\n* Giving written consent to the study.\n\nExclusion Criteria:\n\n* Having previously received advanced training or clinical assignment in preeclampsia\u002Feclampsia management.\n* Regularly using a similar digital game developed on the subject.\n* Health or cognitive limitations that prevent continuation of the research process (according to the student's statement).","FEMALE",{"count":353,"type":22},120,[25],"Preeclampsia and eclampsia are among the leading causes of maternal death and morbidity, and are obstetric emergencies that lead to serious complications during pregnancy. Preeclampsia affects 2-8% of pregnancies worldwide; approximately 46,000 maternal deaths and approximately 500,000 fetal or neonatal deaths occur annually due to preeclampsia. This situation highlights the importance of well-equipped midwifery care, especially in terms of early diagnosis, accurate assessment, emergency intervention, and effective management.\n\nTraditional teaching methods alone are insufficient for midwifery students to develop clinical decision-making skills in life-threatening situations such as preeclampsia and eclampsia, and to translate theoretical knowledge into practice. Therefore, new teaching approaches that support active learning, interaction, and decision-making processes in education are needed.\n\nIn recent years, digital game-based learning has emerged as an innovative tool in health education with its potential to attract learners' attention, improve problem-solving skills, and increase their motivation. Especially for midwifery students, digital games facilitate experiential learning by providing a safe simulation environment in preparation for information overload and stressful clinical environments.\n\nHowever, the use of digital games in teaching complex clinical processes such as preeclampsia and eclampsia management has been researched to a limited extent. Scientifically examining the effects of such innovative methods on students' learning motivation, attitude, and active participation in the learning process in midwifery education will fill an important gap in the literature. In this context, evaluating digital game-based learning in preeclampsia-eclampsia management education by comparing it with simulation training and traditional teaching will make a significant contribution to both the midwifery education literature and the knowledge base regarding the use of technology in health education.",[357],"Healthy Adult",[359,360,361,362],"digital game based learning","preeclampsia","eclampsia","midwifery education","2026-05-03",{"date":365,"type":43},"2026-05-05",{"date":367,"type":22},"2026-06-01",{"date":369,"type":22},"2027-01-30",{"name":49,"class":50},{"id":372,"slug":373,"hasResults":12,"nctId":374,"briefTitle":375,"officialTitle":376,"acronym":377,"eligibilityCriteria":378,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":379,"enrollmentInfo":380,"targetDuration":382,"studyType":113,"phases":4,"briefSummary":383,"conditions":384,"keywords":393,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":400,"lastUpdatePostDateStruct":401,"startDateStruct":402,"completionDateStruct":404,"leadSponsor":405,"locationsCount":406},"100600524","a-new-tool-for-extubation-readiness-in-mechanically-ventilated-patients-readiness-for-extubation-score-100600524","NCT07098611","A New Tool for Extubation Readiness in Mechanically Ventilated Patients: Readiness for EXtubation Score","A New Tool for Extubation Readiness in Mechanically Ventilated Patients: Readiness for EXtubation Score (REXs STUDY)","REXs","Inclusion Criteria:\n\n\\- Patients who are in the weaning process from mechanical ventilation after being connected to invasive mechanical ventilation in the intensive care unit.\n\nExclusion Criteria:\n\n* Patients without legal guardian consent.\n* Tracheostomized patients.\n* Patients enrolled in other studies.\n* Individuals with diaphragmatic pacers.\n* Pregnant patients.","89 Years",{"count":381,"type":22},470,"6 Weeks","Liberation from mechanical ventilation involves three steps: weaning, readiness assessment, and extubation. Readiness is determined using clinical criteria such as improvement of the underlying condition, hemodynamic stability, and adequate respiratory effort. Successful extubation is defined as not requiring invasive support within 48 hours. Due to the complexity of ICU patients, various clinical parameters and multi-component scores have been developed to predict extubation success. This study aims to develop and evaluate a multi-component score, the Readiness for EXtubation score (REXs), to predict extubation readiness in ICU patients under invasive mechanical ventilation.",[385,386,387,388,389,390,391,392],"Ventilator Weaning","Respiration, Artificial","Respiratory Failure","Extubation Readiness","Extubation Failure","Extubation Succeeded","Intensive Care Patients Invasively Ventilated","Weaning Invasive Mechanical Ventilation",[394,395,396,397,398,399],"mechanical ventilation","extubation","weaning","readiness","prediction","score","2026-04-29",{"date":365,"type":43},{"date":403,"type":43},"2025-06-15",{"date":121,"type":22},{"name":49,"class":50},7,{"id":408,"slug":409,"hasResults":12,"nctId":410,"briefTitle":411,"officialTitle":412,"acronym":413,"eligibilityCriteria":414,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":261,"enrollmentInfo":415,"targetDuration":4,"studyType":23,"phases":416,"briefSummary":417,"conditions":418,"keywords":420,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":434,"lastUpdatePostDateStruct":435,"startDateStruct":437,"completionDateStruct":439,"leadSponsor":441,"locationsCount":80},"100610625","combined-motor-imagery-and-vestibular-rehab-for-ms-100610625","NCT07230015","Combined Motor Imagery and Vestibular Rehab for MS","The Effectiveness of Combination of Motor Imagery and Vestibular Rehabilitation on Balance, Cognition, and Quality of Life in Patients With Multiple Sclerosis","MIVR-MS","inclusion criteria\n\n1. Diagnosis of Multiple Sclerosis (MS) Confirmed using McDonald Criteria\n2. Patient diagnosed relapsing-remitting multiple sclerosis (RRMS).\n3. Mild MS between 0-3 according to PDDS.\n4. Age from (18-45)\n5. Mild cognitive impairment\n6. Balance impairment (mild to moderate impairment)\n7. Vestibular dysfunction Related to MS (dizziness, vertigo , gaze instability ) 8. Native language is Arabic to ensure clear communication during cognitive tasks and exercise instructions\n\n9\\. Be able to joined the treatment (motor imagery, vestibular rehabilitaiton )\n\nExclusion Criteria:\n\nOther neurological disorder, progressive multiple sclerosis Non-MS related vestibular disorders (e.g., BPPV, Meniere's disease) that would interfere with vestibular rehab.\n\nSevere Psychiatric Conditions (schizophrenia, bipolar, etc) Sever balance disorder Sever fatigue Medical instability eg (cardiovascular disease, respiratory, infections, severe uncontrolled diabetes, or severe visual impairments.) Sever cognitive impairment Pregnant Advance disability ( wheelchair , unable to stand ) Use of Vestibular-Suppressing Medications Non - speaker Arabic",{"count":89,"type":22},[25],"This trial investigates the first combined use of motor imagery and vestibular rehabilitation in multiple sclerosis, aiming to evaluate their joint effect on balance, cognition, and quality of life.",[419],"Multiple Sclerosis (MS) - Relapsing-remitting",[421,422,423,424,425,426,427,428,429,430,431,432,433],"physical therapy","neurological rehabilitation","MS","Vestibular rehabilitation","Motor imagery","balance","QOL","Cognation","randomized control trial","physical therapy modalities","Physical therapy and rehabilitation","physical performance","Multiple Sclerosis","2026-04-26",{"date":436,"type":43},"2026-04-30",{"date":438,"type":43},"2025-12-01",{"date":440,"type":22},"2026-07-20",{"name":49,"class":50},{"id":443,"slug":444,"hasResults":12,"nctId":445,"briefTitle":446,"officialTitle":447,"acronym":4,"eligibilityCriteria":448,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":449,"targetDuration":4,"studyType":23,"phases":451,"briefSummary":452,"conditions":453,"keywords":457,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":464,"lastUpdatePostDateStruct":465,"startDateStruct":467,"completionDateStruct":469,"leadSponsor":470,"locationsCount":80},"100634037","venous-tourniquet-vs-arterial-tourniquet-for-seizure-monitoring-in-ect-100634037","NCT07534475","Venous Tourniquet vs. Arterial Tourniquet for Seizure Monitoring in ECT","Comparison of Venous Tourniquet Method With Isolated Forearm Technique in Electroconvulsive Therapy in Terms of Efficacy and Safety","Inclusion Criteria:\n\n* Patients scheduled for elective Electroconvulsive Therapy (ECT).\n* ASA (American Society of Anesthesiologists) physical status I to III.\n\nExclusion Criteria:\n\n* Known neuromuscular diseases (e.g., Myasthenia Gravis).\n* Known allergy or hypersensitivity to sugammadex, rocuronium, ketamine, dexmedetomidine, or propofol.\n* Presence of venous insufficiency, lymphedema, or active infection in the upper extremities.\n* Severe cardiovascular instability.",{"count":450,"type":22},20,[25],"This prospective, open-label clinical trial aims to compare a novel \"Venous Tourniquet with Regional Low-Dose Sugammadex\" method against the gold standard \"Arterial Tourniquet\" (Isolated Forearm Technique - IFT) for monitoring motor seizure activity during Electroconvulsive Therapy (ECT). Using a within-subject (intra-individual) design, each of the 40 enrolled patients will receive an arterial tourniquet on one arm and a venous tourniquet on the other arm simultaneously. The study will evaluate clinical efficacy in observing motor seizures, comparing the duration and visibility between the two limbs of the same patient, as well as assessing overall patient comfort and hemodynamics.",[454,455,456],"Major Depressive Disorder","Bipolar Disorder","Schizophrenia",[458,459,460,461,462,463],"Electroconvulsive Therapy","Isolated Forearm Technique","Sugammadex","Neuromuscular Blockade","Seizure Monitoring","Tourniquet","2026-04-16",{"date":466,"type":43},"2026-04-21",{"date":468,"type":22},"2026-04-20",{"date":117,"type":22},{"name":49,"class":50},{"id":472,"slug":473,"hasResults":12,"nctId":474,"briefTitle":475,"officialTitle":476,"acronym":4,"eligibilityCriteria":477,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":478,"targetDuration":4,"studyType":23,"phases":479,"briefSummary":480,"conditions":481,"keywords":4,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":484,"lastUpdatePostDateStruct":485,"startDateStruct":486,"completionDateStruct":487,"leadSponsor":488,"locationsCount":80},"100634038","sacral-erector-spinae-plane-block-in-pilonidal-sinus-surgery-100634038","NCT07534488","Sacral Erector Spinae Plane Block in Pilonidal Sinus Surgery","Evaluation of the Efficacy of Ultrasound-Guided Sacral Erector Spinae Plane Block in Postoperative Analgesia Management in Patients Undergoing Pilonidal Sinus Surgery","Inclusion Criteria:\n\n* Patients scheduled for elective pilonidal sinus surgery.\n* ASA physical status I and II\n\nExclusion Criteria:\n\n* Allergy or sensitivity to local anesthetics or opioid drugs.\n* Infection at the block site.\n* Alcohol or drug addiction.\n* Use of anticoagulant agents.\n* Patient refusal.",{"count":296,"type":22},[25],"This study aims to evaluate the efficacy of ultrasound-guided Sacral Erector Spinae Plane (ESP) block for postoperative analgesia management in patients undergoing pilonidal sinus surgery under general anesthesia",[482,483],"Sacral Erector Spinae Plane Block","Pilonidal Sinus","2026-04-09",{"date":464,"type":43},{"date":468,"type":22},{"date":149,"type":22},{"name":49,"class":50},{"id":490,"slug":491,"hasResults":12,"nctId":492,"briefTitle":493,"officialTitle":494,"acronym":495,"eligibilityCriteria":496,"healthyVolunteers":59,"sex":351,"minAge":497,"maxAge":498,"enrollmentInfo":499,"targetDuration":4,"studyType":23,"phases":500,"briefSummary":501,"conditions":502,"keywords":507,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":511,"lastUpdatePostDateStruct":512,"startDateStruct":514,"completionDateStruct":515,"leadSponsor":517,"locationsCount":80},"100632821","binaural-beat-music-virtual-reality-and-hormones-in-childbirth-100632821","NCT07518667","Binaural Beat Music, Virtual Reality, and Hormones in Childbirth","The Effect of Binaural Rhythm-Supported Music and Virtual Reality Experience on Labor Pain and Hormones","VR","Inclusion Criteria:\n\n* Able to speak Turkish and communicate verbally\n* No hearing or visual impairments\n* The pregnancy is at term (37-42 weeks of gestation) and labor has begun\n* Single fetus with cephalic presentation\n* No chronic disease\n* Not taking hormone therapy\n* Pregnant women who do not have any obstetric risks and are expected to give birth normally\n\nExclusion Criteria:\n\n* Diagnosed with risky pregnancy\n* Complications during birth\n* Those with vision and hearing problems\n* Any pharmacological pain-reducing method applied\n* Cesarean section planned\n* Those who have experienced any alternative methods for preparing for birth or managing labor pain (such as yoga, meditation, breathing exercises, hypnosis)","20 Years","35 Years",{"count":238,"type":22},[25],"This study aims to investigate the effects of Binaural Beats-supported music and virtual reality experience on the levels of oxytocin, prolactin, catecholamine, endorphin, prostaglandin E and cortisol, which are hormones that play an active role in birth, using the Elisa method. Additionally, the study will examine the effects of virtual reality experience and Binaural Beats-supported music during labor on labor pain and some birth outcomes (such as the presence of an episiotomy, the onset of labor, the duration of labor, and the newborn Apgar score).The randomized controlled study will consist of three groups: a virtual reality group, a Binaural Beats-supported music group, and a control group. The research will be completed with a total of 90 people, with 30 people in each group. The research will be conducted at the Maternity Ward of Istanbul Gaziosmanpaşa Training and Research Hospital. Ethics committee approval has been received for the research. Data collection has not yet begun. An application has been made to the hospital administration for institutional permission. The research will begin once the permissions are received.",[503,504,505,506],"Birth","Hormones","Virtual Reality","Music",[503,508,221,509,510],"hormones","Binaural beats","music","2026-04-02",{"date":513,"type":43},"2026-04-08",{"date":282,"type":22},{"date":516,"type":22},"2027-07",{"name":49,"class":50},{"id":519,"slug":520,"hasResults":12,"nctId":521,"briefTitle":522,"officialTitle":523,"acronym":4,"eligibilityCriteria":524,"healthyVolunteers":59,"sex":17,"minAge":18,"maxAge":525,"enrollmentInfo":526,"targetDuration":4,"studyType":113,"phases":4,"briefSummary":528,"conditions":529,"keywords":533,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":538,"lastUpdatePostDateStruct":539,"startDateStruct":541,"completionDateStruct":543,"leadSponsor":545,"locationsCount":4},"100631490","occupational-balance-time-management-and-stress-in-double-major-students-100631490","NCT07501364","Occupational Balance, Time Management and Stress in Double Major Students","The Relationship Between Occupational Balance, Time Management and Perceived Stress in University Students Enrolled in a Double Major Program","Inclusion Criteria:\n\n* Voluntarily agreeing to participate in the study\n* Being an undergraduate university student.\n* Being actively enrolled in a double major program.\n* Having been enrolled in the double major program for at least one semester.\n* Having Turkish reading and comprehension skills.\n* Having no history of psychiatric diagnosis.\n\nExclusion Criteria:\n\n* Inactive enrollment in a double major program\n* Enrollment in an associate degree double major program\n* Incomplete or incorrectly completed questionnaires","30 Years",{"count":527,"type":22},150,"This study aims to examine the relationship between occupational balance, time management, and perceived stress in university students enrolled in a double major program. Participants who voluntarily agree to participate and meet the inclusion criteria will complete online questionnaires assessing their socio-demographic characteristics, occupational balance, time management skills, and perceived stress levels.",[530,531,532],"Occupational Balance","Time Management","Stress, Psychological",[534,535,536,537],"Double major students","Occupational balance","Time management","Perceived stress","2026-03-26",{"date":540,"type":43},"2026-03-30",{"date":542,"type":22},"2026-04-01",{"date":544,"type":22},"2026-04-10",{"name":49,"class":50},{"id":547,"slug":548,"hasResults":12,"nctId":549,"briefTitle":550,"officialTitle":551,"acronym":4,"eligibilityCriteria":552,"healthyVolunteers":12,"sex":553,"minAge":554,"maxAge":555,"enrollmentInfo":556,"targetDuration":4,"studyType":23,"phases":558,"briefSummary":559,"conditions":560,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":563,"lastUpdatePostDateStruct":564,"startDateStruct":566,"completionDateStruct":568,"leadSponsor":570,"locationsCount":80},"100625753","comparison-of-sacral-esp-block-and-dorsal-penile-nerve-block-in-pediatric-hypospadias-surgery-100625753","NCT07426731","Comparison of Sacral ESP Block and Dorsal Penile Nerve Block in Pediatric Hypospadias Surgery","Comparison of the Effects of Sacral Erector Spinae Plane Block and Dorsal Penile Nerve Block on Postoperative Pain Management in Pediatric Patients Undergoing Hypospadias Surgery","Inclusion Criteria:\n\n* Pediatric male patients aged 1-7 years.\n* ASA (American Society of Anesthesiologists) physical status I or II.\n* Scheduled for elective hypospadias surgery.\n* Written informed consent obtained from parents\u002Fguardians\n\nExclusion Criteria:\n\n* History of neurological deficit or developmental delay.\n* Bleeding diathesis or known coagulopathy.\n* History of allergy to local anesthetics.\n* Infection or skin lesion at the block injection site.\n* Congenital spinal anomaly.\n* Mental retardation or history of psychiatric disease.\n* Liver or kidney dysfunction","MALE","1 Year","7 Years",{"count":557,"type":22},70,[25],"This randomized controlled trial aims to compare the postoperative analgesic efficacy of ultrasound-guided Sacral Erector Spinae Plane (ESP) block versus Dorsal Penile Nerve Block (DPNB) in pediatric patients aged 1-7 years undergoing hypospadias surgery. The primary outcome is the pain score assessed by the FLACC scale at the 12th postoperative hour",[561,562],"Postoperative Pain","Hypospadias","2026-03-19",{"date":565,"type":43},"2026-03-20",{"date":567,"type":43},"2026-02-13",{"date":569,"type":22},"2026-05-01",{"name":49,"class":50},{"id":572,"slug":573,"hasResults":12,"nctId":574,"briefTitle":575,"officialTitle":576,"acronym":4,"eligibilityCriteria":577,"healthyVolunteers":12,"sex":17,"minAge":578,"maxAge":579,"enrollmentInfo":580,"targetDuration":4,"studyType":113,"phases":4,"briefSummary":582,"conditions":583,"keywords":4,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":585,"lastUpdatePostDateStruct":586,"startDateStruct":588,"completionDateStruct":590,"leadSponsor":591,"locationsCount":4},"100629884","proprioception-kinesiophobia-and-functional-recovery-after-gonarthrosis-surgery-100629884","NCT07480473","PROPRIOCEPTION, KINESIOPHOBIA AND FUNCTIONAL RECOVERY AFTER GONARTHROSIS SURGERY","THE RELATIONSHIP BETWEEN PROPRIOCEPTION, KINESIOPHOBIA, BALANCE, AND SENSORY PROFILE WITH FUNCTIONAL RECOVERY AFTER GONARTHROSIS SURGERY","Inclusion Criteria:\n\n* The study included individuals aged 50-75 years who had undergone unilateral total knee arthroplasty and were 4-6 weeks post-operatively. Participants were required to have the cognitive capacity to understand the study instructions and to be able to walk independently.\n\nExclusion Criteria:\n\n* Individuals who had undergone bilateral total knee arthroplasty, those with advanced osteoarthritis in the other knee, those with neurological or orthopedic diseases affecting mobility, those who had undergone another major joint surgery within the last six months, and those with vestibular system disease were excluded from the study.","50 Years","75 Years",{"count":581,"type":22},75,"This observational study aims to investigate the relationships between proprioception, causes of kinesiophobia, sensory processing characteristics, and functional recovery in individuals undergoing gonarthrosis surgery. Postoperative functional recovery can be influenced by sensorimotor and psychological factors such as impaired proprioception, fear of movement, and changes in sensory processing. However, the interaction between these factors has not been sufficiently clarified. Participants will complete a sociodemographic and clinical information form, the Western Ontario and McMaster University Osteoarthritis Index (WOMAC), the Causes of Kinesiophobia Scale, and the Adolescent\u002FAdult Sensory Profile. Proprioception will be assessed using the Joint Position Perception Test.",[584],"Knee Osteoarthritis (OA)","2026-03-14",{"date":587,"type":43},"2026-03-18",{"date":589,"type":22},"2026-04-04",{"date":306,"type":22},{"name":49,"class":50},{"id":593,"slug":594,"hasResults":12,"nctId":595,"briefTitle":596,"officialTitle":597,"acronym":4,"eligibilityCriteria":598,"healthyVolunteers":59,"sex":17,"minAge":599,"maxAge":600,"enrollmentInfo":601,"targetDuration":4,"studyType":23,"phases":603,"briefSummary":604,"conditions":605,"keywords":607,"overallStatus":94,"whyStopped":4,"lastUpdateSubmitDate":612,"lastUpdatePostDateStruct":613,"startDateStruct":615,"completionDateStruct":617,"leadSponsor":619,"locationsCount":80},"100628960","effects-of-a-parenting-skills-training-program-on-maternal-self-efficacy-perceived-social-support-and-infant-development-in-mothers-of-preterm-infants-aged-6-12-months-100628960","NCT07468435","Effects of a Parenting Skills Training Program on Maternal Self-Efficacy, Perceived Social Support, and Infant Development in Mothers of Preterm Infants Aged 6-12 Months","Investigation of the Effects of a Parenting Skills Training Intervention Applied to Mothers of Preterm Infants Aged 6-12 Months on Maternal Parenting Self-Efficacy, Perceived Social Support, and Infant Developmental Level","Inclusion Criteria:\n\n* For Mothers Being able to read and write in Turkish Providing written informed consent Having a preterm infant with a corrected age between 6 and 12 months Not having a diagnosed psychiatric disorder\n* For Infants Being born preterm between week of 32 and 37 Not presenting any neurological or other conditions Having a corrected age between 6 and 12 months\n\nExclusion Criteria:\n\n* For Mothers Having any neurological, musculoskeletal and psychiatric diagnosis to effect the caregiving role\n* For Infants Use of multiple daily medications Hospitalization in the neonatal intensive care unit (NICU) for longer than 2 months","6 Months","12 Months",{"count":602,"type":22},26,[25],"The goal of this clinical trial is to evaluate whether a structured parenting skills training intervention can improve maternal parenting self-efficacy, perceived social support, and infant developmental outcomes in mothers of preterm infants aged 6-12 months (corrected age).\n\nThe main questions it aims to answer are:\n\nDoes a parenting skills training intervention improve maternal parenting self-efficacy?\n\nDoes the intervention increase mothers' perceived social support and positively influence infant developmental levels?\n\nResearchers will compare mothers who receive the parenting skills training intervention with a control group receiving standard care to determine whether the intervention leads to greater improvements in maternal and infant outcomes.\n\nParticipants will:\n\nComplete baseline, post-intervention, and follow-up assessments of parenting self-efficacy and perceived social support\n\nHave their infants assessed using standardized developmental evaluation tools\n\nParticipate in a structured, home-based parenting skills training program consisting of multiple sessions (intervention group only)\n\nTake part in semi-structured interviews before and after the intervention to share their experiences and perceived needs",[606],"Prematurity",[608,609,610,611],"parental self-efficacy","social support","preterm infants","parenting skills","2026-03-09",{"date":614,"type":43},"2026-03-12",{"date":616,"type":22},"2026-03-13",{"date":618,"type":22},"2026-08-30",{"name":49,"class":50},{"id":621,"slug":622,"hasResults":12,"nctId":623,"briefTitle":624,"officialTitle":625,"acronym":4,"eligibilityCriteria":626,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":579,"enrollmentInfo":627,"targetDuration":4,"studyType":23,"phases":628,"briefSummary":629,"conditions":630,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":634,"lastUpdatePostDateStruct":635,"startDateStruct":637,"completionDateStruct":638,"leadSponsor":640,"locationsCount":80},"100626528","sps-block-vs-surgical-intercostal-block-for-chronic-pain-after-thoracoscopic-surgery-100626528","NCT07436806","SPS Block vs. Surgical Intercostal Block for Chronic Pain After Thoracoscopic Surgery","Evaluation of Serratus Posterior Superior (SPS) Block Versus Surgical Intercostal Blockade in Preventing Chronic Post-Thoracotomy Pain After Video-Assisted Thoracoscopic Surgery (VATS): A Randomized, Prospective, Comparative Study.","Inclusion Criteria:\n\n* ASA physical status I-III.\n* Scheduled for elective unilateral Video-Assisted Thoracoscopic Surgery (VATS).\n\nExclusion Criteria:\n\n* History of allergy to local anesthetics.\n* Pre-existing chronic pain syndrome or neuropathic pain.\n* Psychiatric disorders affecting pain assessment.\n* Coagulation disorders.\n* Previous thoracic surgery on the same side.",{"count":21,"type":22},[25],"This study aims to evaluate the efficacy of ultrasound-guided Serratus Posterior Superior (SPS) block compared to surgeon-administered intercostal blockade in preventing chronic pain at 3, 6, and 12 months following Video-Assisted Thoracoscopic Surgery (VATS).",[631,632,633],"Chronic Post-thoracotomy Pain","Neuropathic Pain","Postoperative Pain, Acute","2026-03-06",{"date":636,"type":43},"2026-03-10",{"date":226,"type":43},{"date":639,"type":22},"2026-12-10",{"name":49,"class":50},{"id":642,"slug":643,"hasResults":12,"nctId":644,"briefTitle":645,"officialTitle":646,"acronym":4,"eligibilityCriteria":647,"healthyVolunteers":12,"sex":553,"minAge":554,"maxAge":555,"enrollmentInfo":648,"targetDuration":4,"studyType":23,"phases":649,"briefSummary":650,"conditions":651,"keywords":4,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":653,"lastUpdatePostDateStruct":654,"startDateStruct":656,"completionDateStruct":657,"leadSponsor":658,"locationsCount":80},"100625758","comparison-of-posterior-qlb-and-qipb-in-pediatric-undescended-testis-surgery-100625758","NCT07426796","Comparison of Posterior QLB and QIPB in Pediatric Undescended Testis Surgery.","Comparison of the Effects of Posterior Quadratus Lumborum Block and Quadroiliac Plane Block on Analgesic Consumption in Postoperative Pain Management in Pediatric Patients Undergoing Undescended Testis Surgery","Inclusion Criteria:\n\n* Male pediatric patients aged 1-7 years.\n* ASA physical status I or II.\n* Scheduled for unilateral undescended testis surgery.\n* Written informed consent obtained.\n\nExclusion Criteria:\n\n* History of neurological deficit or developmental delay.\n* Bleeding diathesis or known coagulopathy.\n* History of allergy to local anesthetics.\n* Infection or skin lesion at the block injection site.\n* Congenital spinal anomaly.\n* Mental retardation or psychiatric history.\n* Liver or kidney dysfunction.",{"count":557,"type":22},[25],"This randomized, double-blind study compares the postoperative analgesic efficacy of ultrasound-guided Posterior Quadratus Lumborum Block (QLB) versus Quadroiliac Plane Block (QIPB) in pediatric patients aged 1-7 years undergoing unilateral undescended testis surgery.",[561,652],"Cryptorchidism","2026-03-03",{"date":655,"type":43},"2026-03-05",{"date":567,"type":43},{"date":569,"type":22},{"name":49,"class":50},{"id":660,"slug":661,"hasResults":12,"nctId":662,"briefTitle":663,"officialTitle":664,"acronym":4,"eligibilityCriteria":665,"healthyVolunteers":12,"sex":17,"minAge":666,"maxAge":667,"enrollmentInfo":668,"targetDuration":4,"studyType":23,"phases":669,"briefSummary":670,"conditions":671,"keywords":673,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":653,"lastUpdatePostDateStruct":679,"startDateStruct":680,"completionDateStruct":681,"leadSponsor":683,"locationsCount":80},"100616854","neuromuscular-electrical-stimulation-and-leap-motion-based-exercises-in-cerebral-palsy-100616854","NCT07311018","Neuromuscular Electrical Stimulation and Leap Motion-Based Exercises in Cerebral Palsy","The Effects of Neuromuscular Electrical Stimulation and Leap Motion-Based Exercises on Hand Function Parameters in Cerebral Palsy","Inclusion Criteria:\n\n* Diagnosis of spastic unilateral or bilateral cerebral palsy based on clinical and MRI findings.\n* Involvement of the distal upper extremity (wrist and\u002For fingers).\n* Aged between 6 and 15 years.\n* No history of botulinum toxin injection or surgical intervention to the upper extremity within the past 6 months.\n* Gross Motor Function Classification System (GMFCS) levels I-III.\n* Manual Ability Classification System (MACS) levels I-III.\n* Upper extremity spasticity corresponding to 0, 1, or 1+ on the Modified Ashworth Scale (MAS).\n* Passive wrist extension limitation not exceeding 10 degrees.\n* Ability to follow verbal instructions (mental level reported as \"normal\" or \"mild mental retardation\" in the medical record).\n\nExclusion Criteria:\n\n* Currently participating in a specific hand rehabilitation program.\n* Presence of visual or hearing impairment.\n* History of epilepsy.\n* Presence of chronic, orthopedic, or systemic conditions that may interfere with participation.\n* GMFCS levels IV or V.\n* MACS levels IV or V.","6 Years","15 Years",{"count":89,"type":22},[25],"Cerebral palsy (CP) is a group of disorders resulting from a permanent but non-progressive lesion in the developing brain, which affects the development of movement and posture and may lead to activity limitations. Upper extremity involvement is observed in approximately 60% of children with CP. Abnormal muscle tone, imbalance between agonist and antagonist muscles, spasticity, alignment problems, reduced muscle strength, and impaired motor control are among the upper extremity impairments seen in CP. As a result, hand use is typically affected in a way that negatively influences the performance of daily living activities. Upper extremity functionality and hand use are crucial for participation in daily life and overall quality of life in children with CP.\n\nIn addition to conventional rehabilitation methods, advances in technology have introduced various new modalities for upper extremity rehabilitation. The aim of the present project is to investigate the effects of Leap Motion-based exercise intervention and Neuromuscular Electrical Stimulation (NMES) on hand functions in children with spastic CP.\n\nA total of 30 children aged 6-15 years with a diagnosis of spastic CP and distal upper extremity involvement will be included in the study. To evaluate eligibility according to the inclusion criteria, gross motor function level will be assessed using the Gross Motor Function Classification System (GMFCS); hand skills will be assessed using the Manual Ability Classification System (MACS); upper extremity muscle tone will be assessed using the Modified Ashworth Scale (MAS); and passive wrist extension range of motion (ROM) will be measured using an electronic goniometer.\n\nFollowing eligibility confirmation, baseline assessments will be conducted. At baseline wrist ROM will be measured using an electronic goniometer; selective motor control of the wrist will be assessed using the Selective Control of the Upper Extremity Scale (SCUES); hand functions will be evaluated using the Jebsen-Taylor Hand Function Test; daily hand use will be assessed using the ABILHAND-Kids; and wrist extensor and flexor strength and activation will be evaluated via surface electromyography (sEMG).\n\nAll participants will then undergo a 4-week routine conventional exercise program (3 sessions per week, 40 minutes per session). At the end of this 4-week period assessments will be repeated (at week 4). Subsequently, the 30 children with CP will be randomly allocated into two groups: the Leap Motion Control group (n = 15) and the NMES group (n = 15). Both groups will receive an 8-week intervention consisting of 3 sessions per week, each lasting 60 minutes (20 minutes of Leap Motion-based exercises or 20 minutes of NMES application, in addition to 40 minutes of conventional exercises). At the end of the 8-week intervention, all assessments will be repeated ( at week 12).\n\nFor statistical analyses, the Statistical Package for the Social Sciences (SPSS) Version 23.0 for Windows will be used.",[672],"Cerebral Palsy (CP)",[674,675,676,677,678,221],"cerebral palsy","leap motion controller","neuromuscular electrical stimulation","hand function","physiotherapy",{"date":655,"type":43},{"date":309,"type":43},{"date":682,"type":22},"2026-09-15",{"name":49,"class":50},""]