[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Mehmet Incebıyik\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":43},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":5},"100615246","mesh-free-versus-mesh-based-surgery-for-female-stress-urinary-incontinence-a-prospective-comparison-of-pubo-urethral-ligament-plication-and-transobturator-tape-100615246",false,"NCT07290114","Mesh-Free Versus Mesh-Based Surgery for Female Stress Urinary Incontinence: A Prospective Comparison of Pubo-Urethral Ligament Plication and Transobturator Tape","Mesh-Free Versus Mesh-Based Surgery for Female Stress Urinary Incontinence: A Prospective Comparison of Pubo-Urethral Ligament Plication and Transobturator Tape With Short-Term Patient-Centered Outcomes","PLP-TOT","Inclusion Criteria:\n\nFemale patients aged 18-80 years\n\nClinical diagnosis of stress urinary incontinence\n\nFailure of conservative management (pelvic floor exercises or medical therapy)\n\nDesire to undergo surgical treatment (PLP or TOT)\n\nAbility to provide informed consent\n\nWillingness to attend postoperative follow-up visits\n\nExclusion Criteria:\n\n* Mixed urinary incontinence with predominant urge symptoms\n\nActive urinary tract infection\n\nPelvic organ prolapse ≥ stage II\n\nPrevious anti-incontinence surgery\n\nNeurological diseases affecting bladder function\n\nPregnancy or planning pregnancy during follow-up\n\nUncontrolled diabetes, bleeding disorders, or contraindications to surgery\n\nUse of medications affecting bladder function (e.g., anticholinergics)\n\nInability to provide informed consent","FEMALE","18 Years","80 Years",{"count":21,"type":22},147,"ESTIMATED","INTERVENTIONAL",[25],"NA","This prospective clinical study aims to compare the short-term effectiveness, safety, and patient-reported outcomes of two surgical techniques used for the treatment of female stress urinary incontinence (SUI): Pubo-Urethral Ligament Plication (PLP), a mesh-free native tissue repair method, and the Transobturator Tape (TOT) procedure, a commonly used mesh-based mid-urethral sling technique. The study evaluates continence improvement, perioperative and postoperative complications, operative time, hospital stay, postoperative pain, and patient satisfaction. The goal is to provide evidence on whether a mesh-free surgical option such as PLP can offer comparable outcomes to mesh-based TOT, particularly for patients seeking alternatives to synthetic materials.",[28],"Stress Urinary Incontinence (SUI)",[30],"Stress Urinary Incontinence, Pubo-Urethral Ligament Plication, PLP, Transobturator Tape, TOT, Mesh-free surgery, Midurethral sling","RECRUITING","2025-12-04",{"date":34,"type":35},"2025-12-18","ACTUAL",{"date":37,"type":35},"2025-01-13",{"date":39,"type":22},"2026-09",{"name":41,"class":42},"Mehmet Incebıyik","OTHER",""]