[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Mert Ersan\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":51},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":4},"100628846","phase-3-objective-evaluation-of-intradermal-msc-derived-exosome-therapy-on-facial-skin-quality-100628846",false,"NCT07466953","Objective Evaluation of Intradermal MSC-Derived Exosome Therapy on Facial Skin Quality","Objective Analysis of the Effects of Intradermally Administered Mesenchymal Stem Cell-Derived Suspended Exosome Therapy on Facial Skin Quality Using a Standardized Imaging System","Inclusion Criteria:\n\n* • Adults aged 18 to 65 years\n\n  * Individuals presenting facial skin aging signs\n  * Willingness to undergo three intradermal treatment sessions\n  * Ability to comply with study visits and follow-up assessments\n  * Ability to understand the study procedures and provide written informed consent\n\nExclusion Criteria:\n\n* Pregnancy or breastfeeding\n\n  * Active skin infection, inflammatory skin disease, or open wounds in the treatment area\n  * History of allergic reactions to injectable dermatologic treatments\n  * Use of systemic or topical retinoids within the past 6 months\n  * Receipt of facial cosmetic procedures (laser treatment, fillers, botulinum toxin, PRP, or similar treatments) within the past 6 months\n  * Presence of autoimmune disease or immunosuppressive conditions\n  * Active malignancy or ongoing cancer treatment\n  * Participation in another clinical study within the past 3 months",true,"ALL","18 Years","65 Years",{"count":21,"type":22},30,"ESTIMATED","INTERVENTIONAL",[25],"PHASE3","This study aims to evaluate the potential effects of mesenchymal stem cell-derived suspended exosome therapy on facial skin quality using objective imaging analysis. Thirty adult participants will receive intradermal exosome applications in three treatment sessions performed at one-month intervals. Facial skin analysis will be conducted using the VISIA imaging system before each treatment session and six months after the final treatment. The study will examine changes in multiple facial skin characteristics including wrinkles, pigmentation, skin texture, pores, UV spots, red areas, brown spots, and porphyrins to determine whether exosome therapy may improve overall facial skin quality.",[28,29,30],"Skin Aging","Facial Aging","Skin Quality",[32,33,34,35,36,37,38],"Exosome Therapy","Mesenchymal Stem Cell Exosomes","Facial Rejuvenation","Skin Imaging","VISIA Skin Analysis","Skin Aging Treatment","Regenerative Dermatology","NOT_YET_RECRUITING","2026-03-08",{"date":42,"type":43},"2026-03-12","ACTUAL",{"date":45,"type":22},"2026-04-01",{"date":47,"type":22},"2026-12-31",{"name":49,"class":50},"Mert Ersan","OTHER",""]