[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Meta Healthcare Ltd\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":44},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":32,"whyStopped":4,"lastUpdateSubmitDate":33,"lastUpdatePostDateStruct":34,"startDateStruct":37,"completionDateStruct":39,"leadSponsor":41,"locationsCount":4},"100560810","liquid-valine-and-isoleucine-in-maple-syrup-urine-disease-100560810",false,"NCT06581991","Liquid Valine and Isoleucine in Maple Syrup Urine Disease","Valine 50mg\u002Fml and Isoleucine 25mg\u002Fml Oral Solutions for Maple Syrup Urine Disease (MSUD) - Acceptability and Tolerance Study","Inclusion Criteria:\n\n* Male and female MSUD patients ≥1 year and \\\u003C16 years of age.\n* Patients diagnosed with MSUD.\n* Taking both valine and isoleucine supplements for MSUD and willing to take the new supplements for 56 days.\n* Absence of comorbidities.\n* Adherence with dietary management and valine and isoleucine supplements.\n* Able to understand and comply with the requirements of the investigation and sign the Informed Consent Form\u002FAssent form\n\nExclusion Criteria:\n\n* Age \\\u003C1 year old and \\>16 years old.\n* Patients with comorbidities.\n* Any moderate to severe acute illness which in the opinion of the Investigator would interfere with the study procedures or study outcome.\n* History of poor co-operation, non-adherence with dietary management, or poor adherence to investigation procedures.\n* Participation in any other studies involving investigational or marketed products concomitantly or within two weeks prior to entry into the study.","ALL","12 Months","16 Years",{"count":20,"type":21},5,"ESTIMATED","INTERVENTIONAL",[24],"NA","This is a prospective, observational research study in 5 children with Maple Syrup Urine Disease (MSUD). Subjects who are currently taking a valine and isoleucine supplement for MSUD will be recruited for a 56 day trial, of a new ready-to-use valine supplement and a new ready-to-use isoleucine supplement, to evaluate the tolerability and acceptability of the study products compared with their usual products.",[27],"Maple Syrup Urine Disease",[27,29,30,31],"MSUD","Valine","Isoleucine","NOT_YET_RECRUITING","2024-08-29",{"date":35,"type":36},"2024-09-03","ACTUAL",{"date":38,"type":21},"2024-10",{"date":40,"type":21},"2026-09",{"name":42,"class":43},"Meta Healthcare Ltd","INDUSTRY",""]