[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Michael Bau Mortensen\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":42},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":5},"100307303","phase-2-adjuvant-pressurized-intraperitoneal-aerosol-chemotherapy-pipac-in-resected-high-risk-colon-cancer-patients-100307303",false,"NCT03280511","Adjuvant Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) in Resected High Risk Colon Cancer Patients","Adjuvant Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) in Resected High Risk Colon Cancer Patients - The PIPAC-OPC3 CC Trial","Inclusion Criteria:\n\n* Radically resected colon cancer patients with adeno- or signet ring cell carcinomas with high-risk tumors defined as: perforated \u002F pT4NanyM0 (UICC 8th edition) \u002F pTanyNanyM1 with radically resected PM including ovarian metastases\n* Performance status 0-1\n* Fertile women must use approved contraceptives (see below)\n* Age \\> 18 years\n* Written informed consent\n\nExclusion Criteria:\n\n* Radiologically or clinically proven relapse.\n* Previous cytoreductive surgery (CRS) with HIPEC\n* Other malignant diagnosis within the last 2 years\n* Contraindications to laparoscopy (e.g. severe adhesions, peritonitis)\n* A history of allergic reaction to oxaliplatin or other platinum containing compounds\n* Renal impairment, defined as GFR \\\u003C 50 ml\u002Fmin, (Cockcroft-Gault Equation).\n* Myocardial insufficiency, defined as NYHA class \\> 2.\n* Impaired liver function defined as bilirubin ≥ 1.5 x UNL (upper normal limit).\n* Inadequate haematological function defined as ANC ≤ 1.5 x 109\u002Fl and platelets ≤ 100 x 109\u002Fl.\n* Any other condition or therapy, which in the investigator's opinion may pose a risk to the patient or interfere with the study objectives.","ALL","18 Years",{"count":19,"type":20},60,"ESTIMATED","INTERVENTIONAL",[23],"PHASE2","In this study, patients will be offered two Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) treatments with oxaliplatin after primary resection and standard adjuvant chemotherapy (if indicated) for colon cancer. Furthermore, the study will explore, whether it is possible to find free intraperitoneal tumor cells (FITC) after resection and adjuvant chemotherapy for colon cancer.",[26,27,28,29],"Peritoneum Cancer","Peritoneal Carcinomatosis","Peritoneal Metastases","Colo-rectal Cancer","RECRUITING","2022-10-05",{"date":33,"type":34},"2022-10-06","ACTUAL",{"date":36,"type":34},"2017-12-14",{"date":38,"type":20},"2027-03-01",{"name":40,"class":41},"Michael Bau Mortensen","OTHER",""]