[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Michael C Willey\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":103},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,48,72],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":28,"conditions":29,"keywords":31,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100556043","phase-2-can-plia-reduce-early-post-operative-pain-after-pao-surgery-100556043",false,"NCT06519955","Can PLIA Reduce Early Post-operative Pain After PAO Surgery?","Peri-incisional Local Infiltration to Improve Pain Control After Periacetabular Osteotomy","PILA PAO","Inclusion Criteria:\n\n* Adolescent or young adult diagnosed with hip dysplasia indicated for PAO at University of Iowa Hospital and Clinics.\n\nExclusion Criteria:\n\n* Unable to provide informed consent.\n* Pregnant or breast-feeding individuals\n* Prisoner or ward of the state\n* Allergy or medical contradiction to any of the study medications\n* Patients undergoing femoral osteotomy or surgical hip dislocation with PAO will be excluded",true,"ALL","13 Years","50 Years",{"count":22,"type":23},120,"ESTIMATED","INTERVENTIONAL",[26,27],"PHASE2","PHASE3","The goal of this clinical trial is to compare different peri-incisional local infiltrative anesthesia (PLIA) methods in patients ages 13 to 50 undergoing a periacetabular osteotomy (PAO). The main questions to answer here are:\n\n1. Does PLIA impact post-operative pain after PAO?\n2. Does PLIA impact pain medication usage as measured by morphine equivalent dosing (MED) after PAO?\n3. Does the timing of PLIA administration impact post-operative pain and MED after PAO? Participants will be asked to complete some surveys; demographics survey, General Self-Efficacy Scale (GSE) and the Pain Resilience Scale. All other information will be gathered from the patients medical chart.\n\nResearchers will compare three groups. 1.) Patients who do not receive PLIA. 2.) Patients who receive PLIA after their incision is closed. 3.) Patients who receive PLIA throughout PAO.",[30],"Hip Dysplasia",[30,32,33,34],"Periacetabular Osteotomy","PLIA","Peri-Incisional Local Infiltrative Anesthesia","RECRUITING","2026-04-14",{"date":38,"type":39},"2026-04-17","ACTUAL",{"date":41,"type":39},"2024-10-03",{"date":43,"type":23},"2026-09",{"name":45,"class":46},"Michael C Willey","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":4,"eligibilityCriteria":54,"healthyVolunteers":11,"sex":18,"minAge":55,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":24,"phases":58,"briefSummary":59,"conditions":60,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":71},"100519985","phase-2-essential-amino-acid-supplementation-for-femoral-fragility-fractures-100519985","NCT06050668","Essential Amino Acid Supplementation for Femoral Fragility Fractures","MEND Repair & Recover Clinical Trial","Inclusion Criteria:\n\n* Hospital inpatient\n* Age ≥ 65 years old on admission\n* Low-energy mechanism of injury\n* Diagnosis of femur fracture (OTA 31, 32, or 33 fracture)\n* Indicated for surgical fixation\n* Able to provide informed consent\n\nExclusion Criteria:\n\n* Part of a vulnerable population (ex: Incarcerated, Non-English speaking)\n* Cognitive impairment (MMSE score ≤ 17)\n* Electrical medical implant (ex: Pacemaker\u002FDefibrillator, Left Ventricular Assist Device, Cochlear implant, Insulin pump, Pain medication pumps, Spinal cord stimulator)\n* Non-ambulatory prior to injury\n* Inability to consume an oral diet or allergy to supplement ingredients (ex: milk allergy)\n* Concern for inability to complete follow-up\n* Hemi or total arthroplasty (joint replacement)\n* Patients with a historical diagnosis of chronic kidney disease (CKD)","65 Years",{"count":57,"type":23},60,[26],"This trial will evaluate the impact of 4 weeks of postoperative essential amino acid (EAA)-based supplementation on muscle morphology after femoral fragility fracture. This trial will assess the ability of EAA-based to increase skeletal muscle metabolic activity, reduce inflammation, and induce muscle fiber hypertrophy, as well as preserve skeletal muscle mass and physical performance up to 6 months after injury. Participants will be randomized in a 1:1 ratio to 1) standard of care (no dietary intervention) or 2) EAA-based supplementation.",[61,62,63],"Femoral Fracture","Fragility Fracture","Muscle Atrophy",{"date":65,"type":39},"2026-04-15",{"date":67,"type":39},"2024-06-17",{"date":69,"type":23},"2026-12",{"name":45,"class":46},2,{"id":73,"slug":74,"hasResults":11,"nctId":75,"briefTitle":76,"officialTitle":76,"acronym":4,"eligibilityCriteria":77,"healthyVolunteers":11,"sex":18,"minAge":78,"maxAge":79,"enrollmentInfo":80,"targetDuration":4,"studyType":24,"phases":82,"briefSummary":84,"conditions":85,"keywords":90,"overallStatus":96,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":97,"startDateStruct":98,"completionDateStruct":100,"leadSponsor":102,"locationsCount":47},"100365525","psychosocial-interventions-for-young-adults-with-hip-pain-100365525","NCT04039386","Psychosocial Interventions for Young Adults With Hip Pain","Inclusion Criteria:\n\n* We will enroll young adults (15-39) presenting to one of several physical therapy and orthopedic practices in the state of Iowa for treatment of nonarthritic hip pain.\n* Chief complaint of hip pain or dysfunction, and a diagnosis of a nonarthritic hip condition including labral tear, femoroacetabular impingement (FAI), snapping hip, femoral anteversion or dysplasia.\n\nExclusion Criteria:\n\n* Exclusion criteria will include age \\\u003C15 or \\>40 years\n* Difficulty with written English\n* Treatment for alternative conditions such as trochanteric bursitis, hip dislocation, avascular necrosis or fracture.","15 Years","39 Years",{"count":81,"type":23},150,[83],"NA","Psychosocial conditions are common in young adults with hip pain including depression, anxiety, pain catastrophizing, and narcotic use. The incidence of these conditions is not well defined. Interventions to optimize psychosocial conditions with non-surgical or surgical treatments has not been investigated. The goal of this project is to determine the incidence of psychosocial conditions in the young adult population with hip pain and determine if cognitive based therapy can improve clinical outcomes in these individuals.",[30,86,87,88,89],"Hip Pain Chronic","Hip Osteoarthritis","Hip Arthritis","Psychosocial Problem",[91,92,93,94,95],"Hip Pain","Hip Instability","Hip Impingement","Cognitive Based Therapy","Psychosocial Conditions","NOT_YET_RECRUITING",{"date":65,"type":39},{"date":99,"type":23},"2026-09-01",{"date":101,"type":23},"2028-08-01",{"name":45,"class":46},""]