[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Min-Seok Kim\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":73},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,48],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100522116","pulmonary-artery-catheterization-and-carvedilol-early-initiation-in-cardiogenic-shock-due-to-hfref-100522116",false,"NCT06078436","Pulmonary Artery Catheterization and Carvedilol Early Initiation in Cardiogenic SHOCK Due to HFrEF","Pulmonary Artery Catheterization and Carvedilol Early Initiation in Cardiogenic SHOCK Caused by Heart Failure With Reduced Ejection Fraction","PACE-SHOCK","Inclusion Criteria:\n\n* Adults age 19 and above ( no age limit for elderly )\n* Patients with cardiogenic shock requiring intensive care monitoring in ICU\n* Patients eligible for oral medication administration\n* Patients who have provided research participation consent through a written informed consent form\n\nExclusion Criteria:\n\n* Unwilling or unable to obtain informed consent by the participant or substitute decision maker\n* Patients with mechanical circulatory support at the time of screening\n* Patients with acute coronary syndrome\n* Patients with severe valvular heart disease requiring emergent percutaneous procedures or surgery\n* Known hypersensitivity to beta-blockers\n* Patients with a history of bronchospasm or asthma\n* Patients with bradycardia or second or third-degree atrioventricular block\n* Patients with sick sinus syndrome, including sinoatrial block\n* Patients with untreated pheochromocytoma\n* Patients currently undergoing de-sensitization therapy\n* Patients who are currently pregnant, postpartum period within 30 days or breast-feeding","ALL","19 Years",{"count":20,"type":21},160,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study aims to compare the impact of hemodynamic monitoring using pulmonary artery catheter (PAC) on survival and inotropic agent reduction in patients with cardiogenic shock caused by heart failure with reduced ejection fraction (HFrEF). The investigators also intend to compare the difference in long-term survival rates among patients who have recovered from cardiogenic shock due to HFrEF, based on the timing of initiation of beta-blocker treatment.",[27,28],"Heart Failure With Reduced Ejection Fraction","Cardiogenic Shock",[30,31,32,33,34],"Cardiogenic shock","Heart failure with reduced ejection fraction (HFrEF)","Hemodynamic monitoring","Pulmonary artery catheter","Carvedilol","RECRUITING","2024-01-03",{"date":38,"type":39},"2024-01-05","ACTUAL",{"date":41,"type":21},"2024-01",{"date":43,"type":21},"2028-03",{"name":45,"class":46},"Min-Seok Kim","OTHER",1,{"id":49,"slug":50,"hasResults":11,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":56,"targetDuration":4,"studyType":22,"phases":58,"briefSummary":59,"conditions":60,"keywords":62,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":47},"100492936","distal-perfusion-timing-early-or-conservative-to-prevent-limb-ischemia-during-peripheral-va-ecmo-100492936","NCT05698628","Distal Perfusion Timing, Early or Conservative, to Prevent Limb Ischemia During Peripheral VA-ECMO","Comparison Of Conservative Versus Early Distal Perfusion Strategy to Prevent Acute Limb Ischemia in Peripheral Venoarterial Extracorporeal Membrane Oxygenation Patients","DECIDE-ECMO","Inclusion Criteria:\n\n* Age ≥19 years old\n* Refractory cardiogenic shock with peripheral VA-ECMO\n* Informed consent\n\nExclusion Criteria:\n\n* Unwilling or unable to obtain informed consent from the participant or substitute decision-maker\n* Patients who are currently pregnant, postpartum period within 30 days or are breast-feeding\n* VA-ECMO application for causes other than cardiogenic shock\n* Severe coagulopathy\n* Irreversible limb ischemia requiring interventional procedures or surgery at the time of VA-ECMO (previously diagnosed ASO(atherosclerosis obliterans) patients)",{"count":57,"type":21},400,[24],"Peripheral VA-ECMO is widely used in refractory cardiogenic shock patients as a salvage therapy. In most cases, the femoral artery and vein are used for the vascular approach. Large cannulas are usually used for proper oxygenation, which may cause peripheral limb ischemia. Distal perfusion catheterization (DPC) at the ipsilateral arterial cannula site is recommended to prevent distal limb ischemia. However, there is no consensus on the proper timing of DPC and additional invasive procedures may cause complications during VA-ECMO support. In this analysis, the investigators compare the clinical outcomes of distal limb ischemia complications between the conventional DPC group (DPC at the time of limb ischemia sign) and the preemptive DPC group (DPC at the time of VA-ECMO application).",[61],"Extracorporeal Membrane Oxygenation Complication",[63,64,30],"Extracorporeal Membrane Oxygenation","Limb ischemia","2023-06-12",{"date":67,"type":39},"2023-06-15",{"date":69,"type":39},"2023-04-28",{"date":71,"type":21},"2027-02-28",{"name":45,"class":46},""]