[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"MingSight Pharmaceuticals, Inc\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":41},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":4},"100591334","phase-1-a-phase-ib-study-of-the-selective-pkc--inhibitor-ms-553-in-patients-with-refractory-or-relapsed-cllsll-100591334",false,"NCT06979076","A Phase Ib Study of the Selective PKC-β Inhibitor MS-553 in Patients With Refractory or Relapsed CLL\u002FSLL","A Phase Ib Study of the Selective PKC-β Inhibitor MS-553 in Patients With Refractory or Relapsed Chronic Lymphocytic Leukemia\u002FSmall Lymphocytic Lymphoma","Inclusion Criteria:\n\n1. Age 18 years or older.\n2. Diagnosis of CLL or SLL:\n\n   1. History of histologically documented CLL or SLL that meets iwCLL diagnostic criteria according to the 2018 guidelines, and\n   2. Indication for treatment as defined by the 2018 iwCLL guidelines, or the need for disease reduction prior to allogeneic transplantation.-\n\nExclusion Criteria:\n\n1. Current transformation of CLL\u002FSLL non-Hodgkin lymphoma or Hodgkin lymphoma.\n2. Active and uncontrolled autoimmune cytopenia(s).","ALL","18 Years",{"count":19,"type":20},12,"ESTIMATED","INTERVENTIONAL",[23,24],"PHASE1","PHASE2","A Phase Ib Study of the Selective PKC-β Inhibitor MS-553 in Patients with Refractory or Relapsed Chronic Lymphocytic Leukemia\u002FSmall Lymphocytic Lymphoma",[27,28],"CLL (Chronic Lymphocytic Leukemia)","SLL (Small Lymphocytic Lymphoma)","NOT_YET_RECRUITING","2025-09-23",{"date":32,"type":33},"2025-09-29","ACTUAL",{"date":35,"type":20},"2026-07",{"date":37,"type":20},"2028-12",{"name":39,"class":40},"MingSight Pharmaceuticals, Inc","INDUSTRY",""]