[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Misr International University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":338},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,13,0,[8,41,64,91,117,145,177,201,229,253,276,296,317],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100532039","dimensional-changes-following-immediate-implant-placement-in-molar-extraction-sockets-with-or-without-bone-graft-100532039",false,"NCT06207617","Dimensional Changes Following Immediate Implant Placement in Molar Extraction Sockets With or Without Bone Graft","Evaluation of Soft and Hard Tissue Dimensional Changes Following Immediate Implant Placement in Molar Extraction Sockets With or Without Bone Graft: A Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n* Adults from the age of 18 - 50 years of both genders.\n* Patients with non-restorable single bounded mandibular 1st molar tooth indicated for extraction.\n* Periodontally healthy patients with good oral hygiene.\n* Intact interradicular bone with 2-3 mm width, assessed by CBCT.\n* Thin buccal plate of bone (1 mm or less) among both of the mesial and distal root, assessed by CBCT.\n* Intact gingival tissue with at least 2 mm keratinized tissue.\n* Patients accepts to provide written informed consent.\n\nExclusion Criteria:\n\n* Molar sites indicated for extraction with roots of close proximity to vital structures as inferior alveolar nerve.\n* Pregnant females.\n* Smokers as smoking is a contraindication for any plastic periodontal surgery (Khuller, 2009).\n* Handicapped and mentally retarded patients.\n* Patients undergoing chemotherapy and\u002For radiotherapy.\n* Presence of systemic disease that would affect wound healing.\n* Presence of active infection with soft tissue communication.","ALL","18 Years","50 Years",{"count":20,"type":21},28,"ESTIMATED","INTERVENTIONAL",[24],"NA","Statement of problem: The majority of studies on immediate implant placement are related to the maxillary esthetic zone. Literature concerning Immediate implant placement in the posterior region is scarce. Furthermore, there is paucity of evidence on alveolar bone dimensional changes following immediate implant placement in fresh extraction sockets of posterior teeth. Adding to that, negligible evidence is known about the soft tissue alterations which take place during modeling and remodeling phases of socket healing process; regarding the molar sites. Nevertheless, Immediate installation into a molar socket raises an extra challenge for the clinicians, because of the different anatomical features of the extraction sockets compared to that of the single-rooted teeth in the anterior zone. In addition to, implant positioning difficulties; due to the amount of the residual inter-radicular bone after extraction. Aim of the study: To assess the bucco-lingual ridge collapse after immediate implant placement in lower 1st molar sites either with customized healing abutment only; or with xenogeneic bone graft and customized healing abutment. Materials and methods: The current study will include 28 non-restorable lower 1st molar teeth indicated for extraction in the posterior area. Patients will randomly be assigned into two equal groups: the test group; Immediate implant placement + customized healing abutment group and the control group; Immediate implant placement +bone graft+ customized healing abutment group. The presented trial will investigate the following outcomes: bucco-lingual ridge collapse as the primary outcome, together with mid-facial recession, total volume gain\u002Floss, buccal soft tissue contour, bucco-lingual bone width, and vertical bone changes as the secondary outcomes after 12 months",[27],"Immediate Implants","RECRUITING","2026-05-26",{"date":31,"type":32},"2026-05-28","ACTUAL",{"date":34,"type":32},"2026-02-01",{"date":36,"type":21},"2027-08-01",{"name":38,"class":39},"Misr International University","OTHER",1,{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":4,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":48,"targetDuration":50,"studyType":51,"phases":4,"briefSummary":52,"conditions":53,"keywords":4,"overallStatus":55,"whyStopped":4,"lastUpdateSubmitDate":56,"lastUpdatePostDateStruct":57,"startDateStruct":59,"completionDateStruct":61,"leadSponsor":63,"locationsCount":40},"100565896","labial-bone-thickness-around-immediate-implants-in-the-esthetic-zone-following-a-novel-socket-evaluation-system-100565896","NCT06648135","Labial Bone Thickness Around Immediate Implants in the Esthetic Zone Following a Novel Socket Evaluation System","a Novel Socket Evaluation System and Its Impact on Bone Formed Labial to Bone Immediate Anterior Implants. A 1-year Clinical Trial.","Inclusion Criteria:\n\n* Immedaite implants in anterior maxilla\n* thick gingival phenotype\n* intact but thin labial plate of bone (≤1mm)\n* sufficient apical bone to attain implant primary stability (a minimum of 35 Ncm insertion torque)\n\nExclusion Criteria:\n\n* smokers\n* pregnant women\n* patients with systemic disease\n* patients with parafunctional habits such as bruxism or clenching,\n* infected socket\n* periapical pathosis\n* history of radiotherapy or chemotherapy within the past 2 years.",{"count":49,"type":21},25,"5 Months","OBSERVATIONAL","The anterior maxilla is a particularly challenging area for immediate implant placement due to its thin buccal bone walls. These walls are more susceptible to resorption after tooth extraction, which can lead to significant bone loss and inadequate support for an implant. However, Different socket dimension may affect the amount of bone formed labial to the implant, regardless of the garfting procedure.",[54],"Immediate Implant Placement","NOT_YET_RECRUITING","2026-01-27",{"date":58,"type":32},"2026-01-28",{"date":60,"type":21},"2026-03-01",{"date":62,"type":21},"2026-07-01",{"name":38,"class":39},{"id":65,"slug":66,"hasResults":11,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":4,"eligibilityCriteria":70,"healthyVolunteers":71,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":72,"targetDuration":4,"studyType":22,"phases":74,"briefSummary":75,"conditions":76,"keywords":80,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":56,"lastUpdatePostDateStruct":84,"startDateStruct":86,"completionDateStruct":88,"leadSponsor":90,"locationsCount":40},"100565726","novel-soft-tissue-augmentation-technique-using-free-gingival-graft-simultaneous-with-posterior-mandibular-implant-100565726","NCT06645925","Novel Soft Tissue Augmentation Technique Using Free Gingival Graft Simultaneous With Posterior Mandibular Implant","Novel Soft Tissue Augmentation Technique Using Free Gingival Graft Simultaneous With Implant Placement in Posterior Mandible: A 1-year Randomized Clinical Trial","Inclusion Criteria:\n\n* Adults at or above the age of 18.\n* Lower Posterior missing tooth\u002F teeth with minimal KT \\< 2mm\n* Sufficient alveolar ridge length minimum 13-15 mm to IAN\n\n  •. Sufficient alveolar ridge width minimum of 6 mm\n* Patients able to tolerate surgical periodontal procedures.\n* Patients who provided an informed consent and accepted the one-year follow-up period.\n\nExclusion Criteria\n\n* Patients diagnosed with periodontal diseases (Caton et al., 2018).\n* Current or previous smokers.\n* Pregnant and lactating females.\n* Patients with medical conditions that would compromise the surgical procedures; uncontrolled diabetes mellitus, taking intravenous Bisphosphonates for treatment of osteoporosis.\n* Patients with active infection related to the site of implant.\n* Patients with parafunctional habits.\n* Patients with shallow vestibule",true,{"count":73,"type":21},22,[24],"Presence of keratinized tissue (KT) around dental implants, plays a crucial role in stability and health of peri-implant tissues. Several studies reported that, minimum of 2 mm keratinized tissue width is required to achieve long-term longevity. Insufficient keratinized mucosa leads to biofilm accumulation, soft tissue inflammation, eventually peri-implant mucositis and peri-implantitis. Hence, the aim of the present trial is to evaluate KTW gain, linear and volumetric changes in buccal soft tissue along with hard tissue alterations following implant restoration at sites treated either with delayed implant placement \\& simultaneous FGG or the conventional FGG protocol prior to implant placement.",[77,78,79],"Free Gingival Graft","Free Gingival Graft Volume Change","Keratinized Tissue",[81,82,83],"FGG","Delayed implant placement","Keratinized mucosa",{"date":85,"type":32},"2026-01-29",{"date":87,"type":32},"2025-11-01",{"date":89,"type":21},"2027-12-30",{"name":38,"class":39},{"id":92,"slug":93,"hasResults":11,"nctId":94,"briefTitle":95,"officialTitle":96,"acronym":4,"eligibilityCriteria":97,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":98,"targetDuration":4,"studyType":22,"phases":100,"briefSummary":101,"conditions":102,"keywords":104,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":56,"lastUpdatePostDateStruct":111,"startDateStruct":112,"completionDateStruct":114,"leadSponsor":116,"locationsCount":40},"100549573","novel-technique-versus-conventional-subepithelial-connective-tissue-graft-in-treatment-of-ridge-contour-defects-100549573","NCT06435780","Novel Technique Versus Conventional Subepithelial Connective Tissue Graft in Treatment of Ridge Contour Defects","Evaluation of a Novel Technique Versus Conventional Subepithelial Connective Tissue Graft in Treatment of Ridge Contour Defects. A Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n1. Adults above the age of 18 to 50 years.\n2. Males and females as confirmed by asking the female patients about whether they are pregnant or not\n3. Patient's with Seibert classification class I requiring future rehabilitation of one or more premolar region and sound adjacent teeth.\n4. Soft tissue thickness on the palatal tissues more than 6mm at the site of harvesting the graft.\n5. Presence of Mandibular posterior teeth opposing the tooth to be replaced for occlusion.\n6. Clinically healthy soft tissues with no signs of clinical pathology of the soft tissue.\n7. Good oral hygiene.\n8. Patient accepts to sign an informed consent.\n9. ASA I or ASA II Patient.\n\nExclusion Criteria:\n\n1. Patients with ridge defects due to bone defect\n2. Smoker patients who smoke more than 10 cigarettes per day\n3. Pregnant females",{"count":99,"type":21},50,[24],"The aim of the study is to clinically and radiographically evaluate and compare two techniques to augment soft tissues: the conventional subepithelial connective tissue graft technique and a novel denuded interpositional pedicled rolled flap technique (DIPRF) These techniques will be used to augment edentulous ridges that are recommended for rehabilitation by an implant or a fixed restoration.",[103],"Defect in Alveolar Ridge",[105,106,107,108,109,110],"ridge contour defect","soft tissue graft","Rolling Technique","Connective tissue graft","Subepithelial palatal graft","Seibert Class I",{"date":85,"type":32},{"date":113,"type":32},"2023-04-01",{"date":115,"type":21},"2026-12-31",{"name":38,"class":39},{"id":118,"slug":119,"hasResults":11,"nctId":120,"briefTitle":121,"officialTitle":122,"acronym":4,"eligibilityCriteria":123,"healthyVolunteers":71,"sex":16,"minAge":124,"maxAge":125,"enrollmentInfo":126,"targetDuration":4,"studyType":22,"phases":127,"briefSummary":128,"conditions":129,"keywords":132,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":138,"lastUpdatePostDateStruct":139,"startDateStruct":140,"completionDateStruct":142,"leadSponsor":144,"locationsCount":40},"100574527","crestal-bone-changes-following-equi-crestal-versus-subcrestal-implant-placement-100574527","NCT06760442","Crestal Bone Changes Following Equi-crestal Versus Subcrestal Implant Placement","Radiographic Evaluation of Crestal Bone Changes Following Equi-crestal Versus Subcrestal Implant Placement in Mandibular Posterior Augmented Ridge. A Randomized Controlled Clinical Trial.","Inclusion Criteria:\n\n* Patients older than 21 years.\n* Patients having augmented (by 50\u002F50 particulate xenograft and autogenous bone) edentulous posterior site with vertical bone height of \\> 10 mm in the mandible with a width of ridge ≥ 7 mm\n\n  * Adequate Inter-arch space for implant placement\n  * Favorable occlusion (no traumatic occlusion).\n* Good oral hygiene.•Accepts 18 months follow-up period (cooperative patient)\n* The patient provides informed consent.\n\nExclusion Criteria:\n\n* Patients with inadequate bone volume and\u002F or quality\n* Patients with remaining roots or with signs of acute infection related to the area of interest.\n* Patients having systemic conditions that interfere with normal wound healing\n* Patients with habits that may jeopardize the implant longevity and affect the results of the study such as parafunctional habits .\n* Smoker patients.\n* Pregnant women.","21 Years","60 Years",{"count":20,"type":21},[24],"Statement of problem: The stability of peri-implant bone is a crucial factor for the long-term success of dental implants, where crestal bone plays a significant role in both the primary as well as the long- term implant stability. A bone loss of 1.5 mm during the first year of loading has been acceptable according to the early standards. However, more bone stability can be expected with the development in implant designs and surfaces over the past decades.\n\nAim of the study: the aim of this study is to radiographically assess the crestal bone changes following delayed implant placement in mandibular previously augmented posterior sites, comparing cases with equicrestal implant placement with subcrestal implant placement",[130,131],"Implant Therapy","Augmentation, Alveolar Ridge",[133,134,135,136,137],"crestal bone level changes","subcrestal implant position","crestal implant position","augmented ridge","dental implants","2026-01-26",{"date":56,"type":32},{"date":141,"type":32},"2025-01-01",{"date":143,"type":21},"2026-12-01",{"name":38,"class":39},{"id":146,"slug":147,"hasResults":11,"nctId":148,"briefTitle":149,"officialTitle":150,"acronym":4,"eligibilityCriteria":151,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":152,"targetDuration":4,"studyType":22,"phases":154,"briefSummary":157,"conditions":158,"keywords":163,"overallStatus":55,"whyStopped":4,"lastUpdateSubmitDate":138,"lastUpdatePostDateStruct":171,"startDateStruct":172,"completionDateStruct":174,"leadSponsor":176,"locationsCount":4},"100406709","phase-2-anticariogenic-effect-of-moringa-oleifera-mouthwash-compared-to-chlorhexidine-mouthwash-100406709","NCT04575948","Anticariogenic Effect of Moringa Oleifera Mouthwash Compared to Chlorhexidine Mouthwash","Antibacterial, Antiplaque and Anticariogenic Effect of Moringa Oleifera Mouthwash Compared to Chlorhexidine Mouthwash: A Randomized Clinical Trial","Inclusion Criteria:\n\n* Systemically free as reported by the patients\n* Minimum of 20 teeth present in the dentition (excluding wisdom teeth);\n* Clinically healthy gingiva (on intact periodontium)\n* Dental biofilm-induced gingivitis (plaque induced gingivitis) according to the criteria set by the American Academy of Periodontology for classification of periodontal diseases and conditions in 2017\n* Moderate to high caries risk patients\n\nExclusion Criteria:\n\n* Patients with periodontitis or requiring other immediate dental treatments (within the current 6 months)\n* Subjects on antibiotics within last 6 months\n* Periodontal therapy for the past 6 months\n* Pregnant women and lactating mothers\n* Medically compromised patients\n* Subjects with tobacco consumption in any form\n* Subjects wearing partial dentures or having clinically unacceptable restorations or bridges\n* Subjects wearing orthodontic appliances\n* History of allergy to chemical or any herbal products",{"count":153,"type":21},90,[155,156],"PHASE2","PHASE3","Moringa oleifera (MO) is an extraordinary nutritious vegetable tree with high medicinal value for its antibacterial properties. Formulation of various natural dental remedies from this plant and their testing for their effectiveness might yield promising antibacterial, antiplaque and anticariogenic agents with minimal side effects.\n\nAim of the study:\n\nPart I: The aim of this in-vitro part of the study is to formulate a nontoxic mouthwash from MO leaves extract, having antimicrobial activity, to be used in part II of the study. Furthermore, stability and efficacy of the developed mouth wash will be evaluated.\n\nPart II: The aim of this randomized controlled trial is to evaluate the antibacterial, antiplaque and anticariogenic effect of MO mouthwash compared to chlorhexidine mouthwash.",[159,160,161,162],"Plaque, Dental","Antimicrobial","Mouthwash","Cytotoxicity",[164,165,166,167,168,169,170],"Moringa Oleifera","antibacterial activity","mouthwash","chlorhexidine","antiplaque","herbal","translational research",{"date":56,"type":32},{"date":173,"type":21},"2027-12",{"date":175,"type":21},"2028-12",{"name":38,"class":39},{"id":178,"slug":179,"hasResults":11,"nctId":180,"briefTitle":181,"officialTitle":182,"acronym":4,"eligibilityCriteria":183,"healthyVolunteers":11,"sex":184,"minAge":17,"maxAge":185,"enrollmentInfo":186,"targetDuration":4,"studyType":51,"phases":4,"briefSummary":188,"conditions":189,"keywords":191,"overallStatus":55,"whyStopped":4,"lastUpdateSubmitDate":138,"lastUpdatePostDateStruct":196,"startDateStruct":197,"completionDateStruct":199,"leadSponsor":200,"locationsCount":4},"100373140","structural-and-intermediary-social-determinants-of-oral-health-among-egyptian-women-100373140","NCT04138550","Structural and Intermediary Social Determinants of Oral Health Among Egyptian Women","Exploring the Structural and Intermediary Social Determinants of Oral Health Among Egyptian Women: A Cross-Sectional Study","Inclusion Criteria:\n\n* Egyptian women in child bearing age (18-49 years) attending one of the governmental primary healthcare units.\n\nExclusion Criteria:\n\n* Women who recently moved from one place of residence to another.\n* Women attending the dental clinic at one of the primary health units selected for the survey.\n* Pregnant Women.\n* Completely Edentulous Women.\n* Women with mental or psychological issues.","FEMALE","49 Years",{"count":187,"type":21},300,"Globally, there is substantial evidence indicating that low household income, lack of education, poor living conditions and inadequate psycho-social social support are potential risk factors for morbidity and premature death. Despite that, worldwide, there is scarcity in evidence on potential social determinants of oral health among different population groups.The study aims To identify the potential social determinants with an influence on oral health status of Egyptian women.",[190],"Oral Health",[192,193,194,195],"Social determinants","Oral health","Women","Egypt",{"date":56,"type":32},{"date":198,"type":21},"2027-12-01",{"date":175,"type":21},{"name":38,"class":39},{"id":202,"slug":203,"hasResults":11,"nctId":204,"briefTitle":205,"officialTitle":206,"acronym":4,"eligibilityCriteria":207,"healthyVolunteers":71,"sex":16,"minAge":208,"maxAge":209,"enrollmentInfo":210,"targetDuration":4,"studyType":22,"phases":212,"briefSummary":213,"conditions":214,"keywords":216,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":221,"lastUpdatePostDateStruct":222,"startDateStruct":224,"completionDateStruct":225,"leadSponsor":227,"locationsCount":228},"100619129","the-role-of-the-pre-operative-condition-and-artificial-intelligence-assisted-diagnosis-in-predicting-the-success-of-full-pulpotomy-in-symptomatic-permanent-mature-molars-100619129","NCT07340606","The Role of the Pre-operative Condition and Artificial Intelligence-Assisted Diagnosis in Predicting the Success of Full Pulpotomy in Symptomatic Permanent Mature Molars","The Role of Wolters Pulpitis Classification, Apical Periodontitis, and Artificial Intelligence-Assisted Diagnosis in Predicting the Success of Full Pulpotomy in Symptomatic Permanent Mature Molars: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Mature permanent molars with irreversible pulpitis.\n* Presence of bleeding from all canals.\n* The tooth is not periodontally compromised.\n\nExclusion Criteria:\n\n* Non-vital teeth.\n* Uncontrolled bleeding from any of the canals after ten minutes of application of hemostatic agent.\n* Molars with immature roots.","20 Years","45 Years",{"count":211,"type":21},58,[24],"This study aims to evaluate the effect of prognostic factors, such as the severity of pulpal inflammation, carious pulp exposure, and the presence of apical periodontitis, on the success of full pulpotomy in mature permanent molars with irreversible pulpitis. It also aims to investigate the role of artificial intelligence-assisted diagnosis in predicting the prognosis of full pulpotomy.",[215],"Pulpitis - Irreversible",[217,218,219,220],"irreversible pulpitis","full pulpotomy","artificial intelligence","apical periodontitis","2026-01-17",{"date":223,"type":32},"2026-01-21",{"date":221,"type":32},{"date":226,"type":21},"2026-09-01",{"name":38,"class":39},2,{"id":230,"slug":231,"hasResults":11,"nctId":232,"briefTitle":233,"officialTitle":234,"acronym":4,"eligibilityCriteria":235,"healthyVolunteers":71,"sex":16,"minAge":208,"maxAge":4,"enrollmentInfo":236,"targetDuration":4,"studyType":22,"phases":237,"briefSummary":238,"conditions":239,"keywords":241,"overallStatus":55,"whyStopped":4,"lastUpdateSubmitDate":246,"lastUpdatePostDateStruct":247,"startDateStruct":249,"completionDateStruct":251,"leadSponsor":252,"locationsCount":4},"100532036","implants-placed-with-crestal-sinus-approach-versus-osseodensification-in-atrophic-posterior-maxilla-100532036","NCT06207578","Implants Placed With Crestal Sinus Approach Versus Osseodensification in Atrophic Posterior Maxilla","Long Term Stability of Implants Placed With Crestal Sinus Approach Versus Osseodensification in Atrophic Posterior Maxilla. A Randomized Clinical Trial.","Inclusion Criteria:\n\n1. Edentulous atrophic posterior maxillary ridge.\n2. Residual alveolar ridge height within 5-6 mm.\n3. At least 2mm band of keratinized tissue.\n4. Patients with good oral hygiene.\n5. Compliant patients to the follow up periods.\n\nExclusion Criteria:\n\n1. Medically compromised patients.\n2. Smokers.\n3. Pregnant females.\n4. Patients with active periodontal disease.\n5. Bruxer patients.\n6. Patients with chronic or active sinusitis.",{"count":20,"type":21},[24],"However, recently, most described techniques for posterior atrophic maxillary rehabilitation, are targeting more conservative, cost-effective and efficient methods for sinus elevation eliminating its lateral access. The aim of the present study is to evaluate and compare the long-term implant stability for implants placed by the novel crestal sinus approach versus osseodensification using Densa-bur in Atrophic Posterior Maxilla.",[240],"Implants",[242,243,244,245],"osseodensification","densah bur","Crestal implant approach","closed sinus elevation","2025-04-15",{"date":248,"type":32},"2025-04-18",{"date":250,"type":21},"2025-08-01",{"date":87,"type":21},{"name":38,"class":39},{"id":254,"slug":255,"hasResults":11,"nctId":256,"briefTitle":257,"officialTitle":258,"acronym":4,"eligibilityCriteria":259,"healthyVolunteers":71,"sex":16,"minAge":208,"maxAge":4,"enrollmentInfo":260,"targetDuration":4,"studyType":22,"phases":262,"briefSummary":263,"conditions":264,"keywords":265,"overallStatus":55,"whyStopped":4,"lastUpdateSubmitDate":246,"lastUpdatePostDateStruct":270,"startDateStruct":271,"completionDateStruct":273,"leadSponsor":275,"locationsCount":4},"100532035","immediate-implant-placement-utilizing-vestibular-flap-versus-single-flap-approach-with-bone-graft-100532035","NCT06207565","Immediate Implant Placement Utilizing Vestibular Flap Versus Single Flap Approach With Bone Graft","Clinical and Radiographic Evaluation of Immediate Implant Placement Utilizing Vestibular Flap Versus Single Flap Approach With Bone Graft in Anterior Maxilla: A Randomized Clinical Trial","Inclusion Criteria:\n\n* Patients who have one non-restorable maxillary anterior (Canine to Canine region) with sound adjacent teeth.\n* Intact thick biotype gingival tissue with at least 2mm band of keratinized tissue.\n* Buccal bone thickness less than 1mm assessed in CBCT with good apical bone for implant primary stability.\n* Good oral hygiene\n* Patient accepts to provide an informed consent.\n\nExclusion Criteria:\n\n* Smokers\n* Pregnant and lactating females.\n* Medically compromised patients.\n* Patients with active infection related at the site of implant\u002Fbone graft placement.\n* Patients with untreated active periodontal diseases.\n* Patients with parafunctional habits.",{"count":261,"type":21},34,[24],"Due to the evolution of esthetic implant dentistry and tissue regeneration (hard and soft tissue), flap design plays a crucial role in the maintenance and regeneration of the marginal soft tissue and interdental papillae around dental implants. The present study aims to compare soft and hard tissue changes following immediate implant placement with ridge augmentation using the vestibular flap versus single flap approach.",[54],[266,267,268,269],"Immediate implant placement","Anterior Maxilla","Vestibular flap","single flap approach",{"date":248,"type":32},{"date":272,"type":21},"2025-09-01",{"date":274,"type":21},"2026-08-01",{"name":38,"class":39},{"id":277,"slug":278,"hasResults":11,"nctId":279,"briefTitle":280,"officialTitle":281,"acronym":4,"eligibilityCriteria":282,"healthyVolunteers":71,"sex":16,"minAge":208,"maxAge":4,"enrollmentInfo":283,"targetDuration":4,"studyType":22,"phases":285,"briefSummary":286,"conditions":287,"keywords":289,"overallStatus":55,"whyStopped":4,"lastUpdateSubmitDate":246,"lastUpdatePostDateStruct":292,"startDateStruct":293,"completionDateStruct":294,"leadSponsor":295,"locationsCount":4},"100532038","implant-placement-using-open-sinus-elevation-technique-with-and-without-bone-grafting-material-100532038","NCT06207604","Implant Placement Using Open Sinus Elevation Technique With and Without Bone Grafting Material","Survivability of Dental Implants Placed in Atrophic Maxillae Using Open Sinus Elevation Technique With and Without Bone Grafting Material. A Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n1. Edentulous atrophic posterior maxillary ridge.\n2. Residual alveolar ridge height within 3-5mm.\n3. At least 2mm band of keratinized tissue.\n4. Patients with good oral hygiene.\n5. Compliant patients to the follow up periods.\n\nExclusion Criteria:\n\n1. Medically compromised patients.\n2. Smokers.\n3. Pregnant females.\n4. Patients with active periodontal disease.\n5. Bruxer patients.\n6. Patients with chronic or active sinusitis.",{"count":284,"type":21},24,[24],"The success rate of dental implants after graftless sinus augmentation versus conventional sinus augmentation surgery in atrophic maxillae in edentulous patients was investigated and it was concluded that despite the bone gain in ten garftless side, implant survival were significantly lower in the non-grafted side. One year later, Lie et al., conducted a systematic review to evaluate efficacy of graftless maxillary sinus membrane elevation using the lateral window approach for implantation in the atrophic maxilla. It showed a high implant survival rate in non-grafted maxillary sinus lifts and conventional sinus lifts using augmentation materials and there was no significant difference in the ISQ values between both procedures. However, further randomized clinical trials with long-term follow-up were recommended.",[288],"Sinus Elevation",[137,290,291],"bone grafting","posterior maxilla",{"date":248,"type":32},{"date":250,"type":21},{"date":34,"type":21},{"name":38,"class":39},{"id":297,"slug":298,"hasResults":11,"nctId":299,"briefTitle":300,"officialTitle":301,"acronym":4,"eligibilityCriteria":302,"healthyVolunteers":71,"sex":16,"minAge":17,"maxAge":303,"enrollmentInfo":304,"targetDuration":4,"studyType":22,"phases":306,"briefSummary":307,"conditions":308,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":310,"lastUpdatePostDateStruct":311,"startDateStruct":313,"completionDateStruct":315,"leadSponsor":316,"locationsCount":40},"100492142","gingival-recession-rt1-treatment-with-different-gingival-augmentation-surgeries-100492142","NCT05688293","Gingival Recession (RT1) Treatment With Different Gingival Augmentation Surgeries","Gingival Recession (RT1) Treatment With Different Gingival Augmentation Surgeries Compared With Untreated Contralateral Sites: A Randomized Controlled Clinical Study","Inclusion Criteria:\n\n* Medically free patients (American Society of Anesthesiologists I; ASA I)\n* Patients diagnosed with recession (RT1)\n* Fair oral hygiene\n* Patient accepting to provides an informed consent and the follow-up\n\nExclusion Criteria:\n\n* Carious teeth and teeth with periapical infection.\n* Patients diagnosed with periodontitis\n* Smokers\n* Pregnant and lactating females","55 Years",{"count":305,"type":21},30,[24],"Thin gingival phenotype is one of the major causative factors of gingival recession type 1 which can result in hypersensitivity, discomfort, and compromised esthetics. This study assess the efficacy of increasing the gingival thickness from thin gingival phenotype to thick gingival phenotype in the treatment of patients suffering from gingival recession (RT1) and maintenance of results using either connective tissue graft or de-epithelized free gingival graft after non-surgical periodontal debridement compared to non-surgical periodontal debridement alone.",[309],"Gingival Recession","2025-02-08",{"date":312,"type":32},"2025-02-11",{"date":314,"type":32},"2025-02-05",{"date":60,"type":21},{"name":38,"class":39},{"id":318,"slug":319,"hasResults":11,"nctId":320,"briefTitle":321,"officialTitle":322,"acronym":4,"eligibilityCriteria":323,"healthyVolunteers":71,"sex":16,"minAge":17,"maxAge":125,"enrollmentInfo":324,"targetDuration":4,"studyType":22,"phases":326,"briefSummary":327,"conditions":328,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":330,"lastUpdatePostDateStruct":331,"startDateStruct":333,"completionDateStruct":335,"leadSponsor":337,"locationsCount":40},"100546400","clinical-evaluation-of-self-adhesive-bulk-fill-composite-versus-conventional-nano-hybrid-composite-in-cervical-cavities-100546400","NCT06394440","Clinical Evaluation of Self-Adhesive Bulk-Fill Composite Versus Conventional Nano-hybrid Composite in Cervical Cavities","Clinical Evaluation of Self-Adhesive Bulk-Fill Composite Versus Conventional Nano-hybrid Composite in Cervical Cavities - A Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n* Cervical lesions.\n* Cervical lesions of at least one mm depth; to include enamel and dentin.\n* Cervical lesions of not more than 3 mm in depth.\n* Male or female genders.\n* Medically free patients.\n* Normal occlusion.\n* Healthy Gingiva\n\nExclusion Criteria:\n\n* Teeth showing signs of pulpitis or periapical pathosis.\n* Patients older than 60 years.\n* Patients younger than 18 years old.\n* Pregnant women.\n* Patients with history of allergy to resin.\n* Patients with disabilities.\n* Carious cervical lesions extending to proximal surfaces.\n* Carious cervical lesions on the palatal\u002Flingual surfaces.\n* Teeth with root caries.\n* Endodontically treated teeth.",{"count":325,"type":21},54,[24],"The aim of this randomized clinical trial is to compare the six months clinical performance of the self-adhesive bulk-fill composite with the conventional nano-hybrid composite in the cervical lesions of teeth in the esthetic zone. In addition, to evaluate patient's satisfaction towards the self-adhesive bulk-fill material and its total operatory time.",[329],"Cervical Caries","2024-07-04",{"date":332,"type":32},"2024-07-08",{"date":334,"type":32},"2023-03-14",{"date":336,"type":21},"2024-07-30",{"name":38,"class":39},""]