[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Moximed\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":63},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,39],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":17,"targetDuration":4,"studyType":20,"phases":21,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":27,"lastUpdatePostDateStruct":28,"startDateStruct":31,"completionDateStruct":33,"leadSponsor":35,"locationsCount":38},"100580951","motion-clinical-trial-100580951",false,"NCT06843980","MOTION Clinical Trial","Evaluation of the MISHA® Knee System for Symptom Relief in Subjects With Medial Knee Osteoarthritis Versus the Use of Non-surgical Treatment: Randomized Clinical Trial and Comparison of Therapies for Medial Knee Osteoarthritis","Key Inclusion Criteria:\n\n1. Activity exacerbated knee pain isolated to the medial compartment and not global in nature\n2. WOMAC pain ≥ 40\n3. Failed to find relief in non-surgical treatment modalities\n\nKey Exclusion Criteria:\n\n1. Large medial osteophyte(s) or considerable extruded meniscus that may interfere with the placement or function of the device\n2. Poor bone quality (e.g., bony erosion, osteopenia, osteoporosis)\n3. Ligamentous instability\n4. Active or recent knee infection\n5. Inflammatory joint disease, including sequelae of viral infections\n6. Suspected or documented allergy or hypersensitivity to cobalt, chromium, nickel or other metals\n7. History of keloid, hypertrophic or contracture scaring\n8. Propensity for restrictive scar formation or adhesions with prior procedures","ALL",{"count":18,"type":19},100,"ESTIMATED","INTERVENTIONAL",[22],"NA","Prospective, multicenter, two-arm, 2:1 randomized controlled trial (RCT) comparing the benefits in subjects with medial knee osteoarthritis who are treated with either the MISHA Knee System or with non-surgical treatment.\n\nThis is the first randomized head-to-head study comparing outcomes from subjects treated with the MISHA Knee System.",[25],"Osteoarthritis, Knee","RECRUITING","2026-06-02",{"date":29,"type":30},"2026-06-03","ACTUAL",{"date":32,"type":30},"2025-02-13",{"date":34,"type":19},"2030-06-30",{"name":36,"class":37},"Moximed","INDUSTRY",8,{"id":40,"slug":41,"hasResults":11,"nctId":42,"briefTitle":43,"officialTitle":44,"acronym":4,"eligibilityCriteria":45,"healthyVolunteers":11,"sex":16,"minAge":46,"maxAge":47,"enrollmentInfo":48,"targetDuration":4,"studyType":20,"phases":50,"briefSummary":51,"conditions":52,"keywords":4,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":54,"lastUpdatePostDateStruct":55,"startDateStruct":57,"completionDateStruct":59,"leadSponsor":61,"locationsCount":62},"100525219","misha-post-market-clinical-study-100525219","NCT06118892","MISHA Post-Market Clinical Study","Post-Market Evaluation of the MISHA® Knee System for Symptom Relief in Subjects With Medial Knee Osteoarthritis","Key Inclusion Criteria:\n\n1. Subjects aged 25 to 65 years at time of index procedure\n2. Body Mass Index (BMI) of \\\u003C 35\n3. Activity exacerbated knee pain isolated to the medial compartment and not global in nature\n4. WOMAC pain ≥ 40\n5. Failed non-operative OA treatment\n\nKey Exclusion Criteria:\n\n1. Large medial osteophyte(s) or considerable extruded meniscus that may interfere with the placement or function of the device\n2. Poor bone quality (e.g., bony erosion, osteopenia, osteoporosis)\n3. Ligamentous instability\n4. Active or recent knee infection\n5. Inflammatory joint disease, including sequalae of viral infections\n6. Suspected or documented allergy or hypersensitivity to cobalt, chromium, nickel or other metals\n7. History of keloid, hypertrophic or contracture scaring\n8. Propensity for restrictive scar formation or adhesions with prior procedures","25 Years","65 Years",{"count":49,"type":19},120,[22],"Prospective evaluation of the safety and effectiveness of the MISHA Knee System.\n\nThe study will collect data on the procedural and long-term adverse events, WOMAC pain and function scores, KSS satisfaction, subsequent surgical interventions, BMI levels, range of motion, UCLA activity level of the subjects, and perform radiographic\u002Fx-ray evaluations at clinical visits through 5 years post-procedure.\n\nThe primary analysis of this study is freedom from device- and procedure-related SSIs at five (5) years post-implantation.\n\nThis study will also assess device performance in subjects with intact and retained devices and subjects with devices removed prior to study termination and freedom from conversion to arthroplasty through 5 years.\n\nStudy subjects will be followed over a five-year post-implant period.",[53],"Osteo Arthritis Knee","2026-03-31",{"date":56,"type":30},"2026-04-01",{"date":58,"type":30},"2023-11-03",{"date":60,"type":19},"2030-07-30",{"name":36,"class":37},3,""]