[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Muehlenkreiskliniken, MKK\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":82},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,52],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":46,"leadSponsor":48,"locationsCount":51},"100580402","peep-vs-zeep-in-out-of-hospital-cardiac-arrest-100580402",false,"NCT06836830","PEEP vs. ZEEP in Out-of-Hospital-Cardiac-Arrest","Peri-Arrest Ventilation With Positive End-Expiratory-Pressure vs. Zero End-Expiratory-Pressure in Out-of-Hospital-Cardiac-Arrest","PerAVent","Inclusion Criteria:\n\n* Adults \\>= 18 years\n* non-traumatic OHCA\n* mechanical ventilation via airway device\n\nExclusion Criteria:\n\n* Patients \\\u003C 18 years,\n* traumatic cause of OHCA,\n* no cardiac arrest, withholding of resuscitation (e.g. Do-Not-Resuscitate orders)","ALL","18 Years",{"count":20,"type":21},600,"ESTIMATED","INTERVENTIONAL",[24],"NA","Out-of-hospital cardiac arrest (OHCA) remains a major cause of mortality, with low survival probabilities to hospital discharge. Despite the frequent use of airway management and mechanical ventilation during resuscitation, there is limited evidence regarding the optimal ventilation strategy to improve oxygen delivery and patient outcomes. The present study aims to investigate the effects of positive-end-expiratory-pressure (PEEP) set at 5 mbar compared to zero-end-expiratory-pressure (ZEEP) on the return of spontaneous-circulation (ROSC) in adult patients with OHCA.",[27,28,29,30],"Ventilation Therapy","PEEP, Occult","CPR","Cardiac Arrest (CA)",[32,33,34,35,36,37,38,29],"Cardiac Arrest","Positive End-Expiratory Pressure","Zero End-Expiratory Pressure","Ventilation","Randomized Controlled Trial","Emergency Medicine","Resuscitation","RECRUITING","2025-08-05",{"date":42,"type":43},"2025-08-06","ACTUAL",{"date":45,"type":43},"2025-06-01",{"date":47,"type":21},"2026-10-31",{"name":49,"class":50},"Muehlenkreiskliniken, MKK","OTHER",3,{"id":53,"slug":54,"hasResults":11,"nctId":55,"briefTitle":56,"officialTitle":57,"acronym":4,"eligibilityCriteria":58,"healthyVolunteers":59,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":60,"targetDuration":4,"studyType":22,"phases":61,"briefSummary":62,"conditions":63,"keywords":65,"overallStatus":73,"whyStopped":4,"lastUpdateSubmitDate":74,"lastUpdatePostDateStruct":75,"startDateStruct":77,"completionDateStruct":79,"leadSponsor":81,"locationsCount":4},"100584135","intra-arrest-ventilation-in-human-cadavers-ii-100584135","NCT06885398","Intra Arrest Ventilation in Human Cadavers II","Intra-Arrest-Ventilation - a Prospective Randomized Trial in Human Cadavers II","Inclusion Criteria:\n\n* more than 18 years of age\n\nExclusion Criteria:\n\n* Adult respiratory distress syndrome (ARDS)\n* Severe lung or thoracic injuries\n* Pneumothorax\n* Abnormal airways\n* Tracheostoma\n* severe aspirations",true,{"count":51,"type":21},[24],"The study investigates the influence of three types of ventilation mode by using Bi-Level positive airway pressure (pinsp 20 mbar, PEEP 5, AF 10\u002Fmin) with two different types of ventilators ( Medumat vs. MeduVENT ), Continuous positive airway pressure (PEEP 5, AF 10\u002Fmin, ASB 10) and Chest Compression Synchronized Ventilation (pInsp = 30 vs. 60 mbar; respiratory rate = chest compression rate, PEEP 5) with regard to achieving a sufficient tidal volume and the tightness of various supraglottic airway devices (laryngeal mask, i-Gel-laryngeal mask, laryngeal tube) and endotracheal intubation.",[64],"Ventilation During Resuscitation",[66,67,68,69,70,71,72],"Cardiac arrest","Airway management","Cadaver","Heart diseases","Heart arrest","Death","cardiovascular diseases","NOT_YET_RECRUITING","2025-03-17",{"date":76,"type":43},"2025-03-20",{"date":78,"type":21},"2025-04-01",{"date":80,"type":21},"2025-12-30",{"name":49,"class":50},""]