[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Nada Mahmoud Soliman\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":42},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":5},"100617238","phase-2-antimicrobial-photodynamic-therapy-with-icg-loaded-nanoparticles-for-periodontitis-management-100617238",false,"NCT07316023","Antimicrobial Photodynamic Therapy With ICG-Loaded Nanoparticles for Periodontitis Management","Efficacy of Antimicrobial Photodynamic Therapy Using Polymeric Nanoparticles Loaded With Indocyanine Green in Management of Periodontitis.(A Randomized Controlled Clinical Trial Study With Microbiological Analysis )","Inclusion Criteria:\n\n* 1- Both genders aged between 36-50 years (Wadhwa et al., 2021) 2- Generalized stage III grade B periodontitis (Papapanou et al., 2018). Posterior teeth, stage III with PD\\>6 mm and CAL ≥5 mm 3- Patients ready to comply with oral hygiene measures. 4- Patients free from any systemic disease that may affect the treatment (Glick et al., 2008)\n\nExclusion Criteria:\n\n* Exclusion criteria:\n\n  1. Smokers\n  2. Pregnant females.\n  3. Drug abusers.\n  4. Patients taking antibiotics or performed any periodontal treatment in the previous 6 months.\n\nJustification for Exclusions:\n\nTo reduce any confounding factors and bias that may affect the results of this study.","ALL","36 Years","50 Years",{"count":20,"type":21},27,"ESTIMATED","INTERVENTIONAL",[24],"PHASE2","To better understand and treat your gum disease, dentists now use a system that stages its severity and grades its speed, rather than using old labels. The recommended first step is almost always a deep cleaning, which is very effective. However, because some bacteria can hide from cleanings and antibiotics, researchers are exploring a promising light-based treatment. This method uses a safe, light-activated dye and a gentle laser to target and kill bacteria without leading to resistance. To make this treatment even stronger, scientists are testing a way to package the dye inside tiny, biodegradable \"containers\" that deliver it directly to the germs. The goal of this research is to see if this advanced delivery method works better than the dye alone, hoping to provide a more powerful, non-surgical option to fight gum disease and protect your teeth.\"",[27],"Stage III Periodontitis",[29],"periodontits\u002F stage III \u002F NSPT\u002FPDT\u002FNano particles\u002F ICG","RECRUITING","2025-12-18",{"date":33,"type":34},"2026-01-05","ACTUAL",{"date":36,"type":21},"2026-01-15",{"date":38,"type":21},"2026-08-30",{"name":40,"class":41},"Nada Mahmoud Soliman","OTHER",""]