[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Namik Kemal University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":179},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,47,74,101,126,155],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100629121","comparative-outcomes-of-subtunical-microdissection-and-grafting-versus-classical-plaque-incision-and-grafting-in-complex-peyronies-disease-100629121",false,"NCT07470528","Comparative Outcomes of Subtunical Microdissection and Grafting Versus Classical Plaque Incision and Grafting in Complex Peyronie's Disease","Peyronie","Inclusion Criteria:\n\n* \\- Male patients aged 18 years or older\n* Diagnosis of Peyronie's disease with stable plaque and stable penile curvature for at least 3 months\n* Presence of complex Peyronie's disease including severe curvature, multiplanar deformity, hinge effect, hourglass deformity, or large plaques causing functional impairment\n* Patients requiring surgical correction with graft-based reconstruction\n* Ability to provide informed consent and comply with follow-up evaluations\n\nExclusion Criteria:\n\n* Ossified Peyronie's plaques requiring plaque excision\n* Congenital penile curvature (congenital chordee)\n* Previous penile prosthesis implantation\n* Active phase Peyronie's disease with progressive curvature or penile pain\n* Severe erectile dysfunction not responsive to medical therapy\n* History of prior penile reconstructive surgery\n* Significant systemic illness preventing surgical treatment\n* Inability to complete postoperative follow-up assessments",true,"MALE","18 Years",{"count":20,"type":21},80,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical study is to compare two surgical techniques used for the treatment of complex Peyronie's disease. Peyronie's disease can cause penile curvature, deformity, and difficulties during sexual intercourse due to fibrotic plaques within the penile tunica albuginea. In patients with severe deformity, surgical correction is often required.\n\nThe main question this study aims to answer is whether subtunical microdissection can provide effective correction of penile curvature while preserving erectile function when compared with the classical plaque incision and grafting technique.\n\nParticipants with complex Peyronie's disease who require surgical correction will undergo either subtunical microdissection or classical plaque incision and grafting. In order to standardize the procedures, the same graft material will be used in both surgical techniques. A bovine pericardial graft will be applied in all cases, and graft size will be determined according to the geometric principles described by Egydio.\n\nIn the subtunical microdissection technique, the subtunical plane beneath the Peyronie's plaque is carefully dissected using microsurgical instruments under approximately 3.5× optical magnification with surgical loupes. In the classical technique, plaque incision is performed followed by graft reconstruction of the tunical defect.\n\nAll surgical procedures will be performed by the same surgical team using a standardized operative approach and a uniform anesthesia protocol.\n\nParticipants will be followed prospectively after surgery to evaluate penile curvature, erectile function, and patient satisfaction. The results of this study may help determine whether subtunical microdissection represents an effective and safe alternative surgical strategy for the treatment of complex Peyronie's disease.",[27],"Peyronie's Disease (PD)",[29,30,31,32,33],"Peyronie's Disease","Complex Peyronie's Disease","Subtunical Microdissection","Plaque Incision and Grafting","Penile Reconstruction","RECRUITING","2026-03-15",{"date":37,"type":38},"2026-03-18","ACTUAL",{"date":40,"type":38},"2025-05-27",{"date":42,"type":21},"2026-12",{"name":44,"class":45},"Namik Kemal University","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":54,"minAge":18,"maxAge":4,"enrollmentInfo":55,"targetDuration":56,"studyType":57,"phases":4,"briefSummary":58,"conditions":59,"keywords":61,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":46},"100510623","sternocleidomastoid-thickness-in-sarcopenia-100510623","NCT05928845","Sternocleidomastoid Thickness in Sarcopenia","Could Changes in Sternocleidomastoid Muscle Thickness be a Predictor of Sarcopenia in Intensive Care Patients?","Inclusion Criteria:\n\n* Patients who are expected to be followed up in the intensive care unit for at least 1 week\n* Patients over 18 years old\n\nExclusion Criteria:\n\n* Patients under 18 years of age\n* Head-neck, femur trauma patients\n* Those with a diagnosis of primary neuromuscular disease\n* Those who have a condition that prevents imaging in the body parts where ultrasonography is planned","ALL",{"count":20,"type":21},"1 Week","OBSERVATIONAL","In order to prevent sarcopenia in intensive care patients and to guide nutritional therapy, evaluation of muscle thickness with ultrasonography is a modern, simple and non-invasive procedure routinely performed by Anesthesiology and Reanimation specialists. Sarcopenia in intensive care patients has been demonstrated in many studies. It has been studied that routine examination of changes in rectus femoris muscle thickness by ultrasonography is a predictor of sarcopenia. However, the muscles in the neck region, such as the sternocleidomastoid muscle, which are easy to examine, have not been studied very well. There is no study in the literature with the sternocleidomastoid muscle. For this reason, we decided to examine the relationship of sternocleidomastoid muscle thickness with patient characteristics, treatments, feeding route and type, feeding time, length of stay in intensive care unit, as in routine measurements of rectus femoris muscle thickness by ultrasonography.",[60],"Sarcopenia",[62,63,64],"sarcopenia","intensive care","ultrasonography","NOT_YET_RECRUITING","2025-06-19",{"date":68,"type":38},"2025-06-25",{"date":70,"type":21},"2025-09-01",{"date":72,"type":21},"2026-02-15",{"name":44,"class":45},{"id":75,"slug":76,"hasResults":11,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":4,"eligibilityCriteria":80,"healthyVolunteers":16,"sex":54,"minAge":18,"maxAge":81,"enrollmentInfo":82,"targetDuration":4,"studyType":22,"phases":84,"briefSummary":85,"conditions":86,"keywords":89,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":4},"100583146","comparison-of-epidural-analgesia-with-intra-articular-infiltration-analgesia-100583146","NCT06872528","Comparison of Epidural Analgesia With Intra-Articular Infiltration Analgesia","Comparison of Epidural Analgesia With Intra-Articular Infiltration Analgesia for Postoperative Total Knee Arthroplasty Analgesia: A Prospective, Randomized Controlled Trial","Inclusion Criteria:\n\n1. Age range 18-75\n2. Those who underwent surgery with combined spinal anesthesia\n3. Drugs administered with combined spinal anesthesia and intra-articular infiltration analgesia\n\nExclusion Criteria:\n\n1. Those who do not want to participate in the study\n2. Those who underwent surgery under general anesthesia\n3. Patients outside the specified age range\n4. Patients with inadequate follow-up results (patient, drug and device related)","75 Years",{"count":83,"type":21},30,[24],"The results of combining infiltrative analgesia applied by orthopedists with epidural analgesia applied by anesthesiologists after knee replacement surgery will be compared.\n\nIt aims to compare epidural analgesia with the maximum reduction of postoperative pain in patients, as well as in terms of both analgesic and complications.\n\nThe study will include patients who have undergone knee replacement surgery for six months. In the study, we will compare the results of painkillers applied to the patient from the waist or knee after the waist numbing anesthesia, which includes some of the routinely applied protocols of your knee replacement surgery. It is a condition that will be monitored after surgery. The study aims to reduce maximum pain with two painkiller methods applied in small amounts or together. No interventional application will be made to the patient who will undergo surgery other than routine application. After the surgery, you will be asked verbally about your pain level and side effects at certain hours after the surgery and the amount of painkillers used and the amount of painkillers will be determined according to the follow-up hours (1st, 2nd, 6th, 12th, 24th and 48th hours after the surgery). In addition to these, complications will also be monitored. The results of patients who can be fully followed up at the end of 6 months will be presented as a scientific study.",[87,88],"Epidural; Analgesia","Local Infiltration",[90,91,92],"Ranawat","Epidural analgesia","Knee replacement surgery","2025-03-10",{"date":95,"type":38},"2025-03-12",{"date":97,"type":21},"2025-03-28",{"date":99,"type":21},"2025-09-28",{"name":44,"class":45},{"id":102,"slug":103,"hasResults":11,"nctId":104,"briefTitle":105,"officialTitle":105,"acronym":4,"eligibilityCriteria":106,"healthyVolunteers":16,"sex":54,"minAge":18,"maxAge":4,"enrollmentInfo":107,"targetDuration":4,"studyType":57,"phases":4,"briefSummary":109,"conditions":110,"keywords":113,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":118,"lastUpdatePostDateStruct":119,"startDateStruct":121,"completionDateStruct":123,"leadSponsor":125,"locationsCount":46},"100571674","the-effect-of-preoperative-culture-timing-on-postoperative-outcomes-of-retrograde-intrarenal-surgery-100571674","NCT06723327","The Effect of Preoperative Culture Timing on Postoperative Outcomes of Retrograde Intrarenal Surgery","Inclusion Criteria:\n\n* Patients over 18 years of age\n* Patients who had a urine culture taken 2 weeks before the operation and reported as sterile\n\nExclusion Criteria:\n\n* Patients under 18 years of age\n* Patients without sufficient data\n* Patients with a urine culture more than 2 weeks before retrograde intrarenal -surgery\n* Patients with a positive urine culture before retrograde intrarenal surgery\n* Patients with renal anatomic anomalies\n* Patients with a solitary (single) kidney",{"count":108,"type":21},1000,"The rate of complications (unexpected situations) after retrograde intrarenal surgery is reported to be 9-25%, and the majority of these are postoperative infections. Surgery must be performed under sterile (microbial-free) urine culture to prevent these complications. There are guideline recommendations regarding sterile urine culture reporting, but it is not clear how long in advance it should be taken. The possibility of the patient becoming infectious again during the period leading up to surgery is a condition that needs to be determined. Therefore, the culture taken before surgery should be compared with the urine culture result taken at the latest possible time before the operation.",[111,112],"Urinary Infections","Urolithiasis",[114,115,116,117],"urine culture","urolithiasis","kidney stone","retrograde intrarenal surgery","2024-12-07",{"date":120,"type":38},"2024-12-12",{"date":122,"type":38},"2024-12-01",{"date":124,"type":21},"2025-12-31",{"name":44,"class":45},{"id":127,"slug":128,"hasResults":11,"nctId":129,"briefTitle":130,"officialTitle":131,"acronym":4,"eligibilityCriteria":132,"healthyVolunteers":16,"sex":54,"minAge":133,"maxAge":134,"enrollmentInfo":135,"targetDuration":4,"studyType":22,"phases":137,"briefSummary":138,"conditions":139,"keywords":141,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":147,"lastUpdatePostDateStruct":148,"startDateStruct":150,"completionDateStruct":152,"leadSponsor":154,"locationsCount":4},"100564365","effect-of-nursing-interventions-on-pain-and-salivary-cortisol-levels-during-heel-stick-in-preterm-newborns-100564365","NCT06628232","Effect of Nursing Interventions on Pain and Salivary Cortisol Levels During Heel Stick in Preterm Newborns","The Effect of Giving a Pacifier Dipped in Breast Milk, Heel Warming, and Applying Both Together on Pain and Salivary Cortisol Levels During Heel Stick in Preterm Newborns: Randomized Controlled Study.","Inclusion Criteria:\n\n* Mother 18 years of age or older\n* Mother is literate\n* Whether the mother gives birth naturally or by caesarean section\n* Uncomplicated pregnancy and birth history in mother\n* Mother\\'s voluntary participation in the study\n* Preterm babies between 34 0\u002F7-36 6\u002F7 weeks\n* Prematurity at 34 0\u002F7-36 6\u002F7 weeks and weight appropriate for the week (Appropriate Gestational Age- AGA),\n* The baby should be fed at least 1 hour in advance.\n* It has been 1 hour since the last painful intervention on the baby.\n* 6Heel blood should be taken 6 hours after taking analgesic, sedative and anticonvulsant medications.\n\nExclusion Criteria:\n\n* The baby has a fever\n* The baby receiving oxygen therapy,\n* The baby receiving antibiotic treatment\n* The baby has a congenital anomaly\n* The baby having the bed side and heater underneath\n* The baby receiving phototherapy,\n* The baby is connected to a mechanical ventilator\n* Babies whose blood was not collected on the first attempt","34 Weeks","36 Weeks",{"count":136,"type":21},18,[24],"Babies born before the thirty-seventh gestational week are called preterm or premature. Most preterm newborns require Neonatal Intensive Care Unit (NICU) care depending on their gestational age and clinical condition. Although many painful invasive procedures are usually performed on newborns in the NICU, the most common procedure is heel prick. Heel prick is a painful and stressful procedure for the newborn. Neonates do not respond to pain verbally; they respond physiologically, behaviorally and hormonally. Physiologic responses of preterm infants to pain include increased heart and respiratory rate, increased blood pressure and intracranial pressure, decreased oxygenation, and sweating of palms. Among the hormonal symptoms caused by stress in newborns, the most commonly used biochemical method is the measurement of cortisol level. It is reported that there is a significant correlation between salivary and plasma cortisol levels and salivary cortisol level reflects plasma cortisol level. This method is particularly preferred because saliva sampling is much less stressful.",[140],"PreTerm Neonate",[142,143,144,145,146],"preterm","leel prick","pain","salivary cortisol","nursing care","2024-10-02",{"date":149,"type":38},"2024-10-04",{"date":151,"type":21},"2024-11-01",{"date":153,"type":21},"2025-11-01",{"name":44,"class":45},{"id":156,"slug":157,"hasResults":11,"nctId":158,"briefTitle":159,"officialTitle":160,"acronym":4,"eligibilityCriteria":161,"healthyVolunteers":11,"sex":17,"minAge":162,"maxAge":163,"enrollmentInfo":164,"targetDuration":4,"studyType":57,"phases":4,"briefSummary":166,"conditions":167,"keywords":4,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":171,"lastUpdatePostDateStruct":172,"startDateStruct":174,"completionDateStruct":176,"leadSponsor":178,"locationsCount":4},"100562694","comparison-of-the-effect-of-testosterone-administered-for-micropenis-hypospadias-surgery-with-bispectral-index-100562694","NCT06606496","Comparison of the Effect of Testosterone Administered for Micropenis Hypospadias Surgery With Bispectral Index","Comparison of the Effect of Testosterone Administered for Micropenis Hypospadias Surgery With Bispectral Index and Other Parameters in General Anesthesia: A Prospective Observational Study","Inclusion Criteria:\n\n* Ages 1-16\n* Patients with ASA I (Normal healthy patients except for surgery)\n* Patients who will undergo surgery for hypospadias repair\n\nExclusion Criteria:\n\n* Morbidly obese patients (body mass index \\> 40kg\u002Fm2)\n* ASA II-III-IV patients (other groups of patients with additional diseases)\n* Volunteers who do not want to participate in the study","1 Year","16 Years",{"count":165,"type":21},22,"The aim of this observational study is to learn the effects of hormone therapy (testosterone) applied in micropenis hypospadias surgery on the depth of anesthesia under general anesthesia. The main question it aims to answer is: The effect of testosterone therapy on the depth of general anesthesia. Based on these, to comment on the depth of anesthesia of patients who have just started using testosterone for sex change. To follow the depth of anesthesia of patients who have undergone hypospadias surgery with BIS monitoring and to record respiratory parameters under general anesthesia.",[168,169,170],"General Anesthesia","Testosterone","BIS","2024-09-18",{"date":173,"type":38},"2024-09-23",{"date":175,"type":21},"2024-09",{"date":177,"type":21},"2024-12",{"name":44,"class":45},""]