[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Natalie Lockney\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":41},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":5},"100451250","phase-1-gabapentin--ketamine-for-preventiontreatment-of-acutechronic-pain-in-locally-advanced-head-and-neck-cancer-100451250",false,"NCT05156060","Gabapentin & Ketamine for Prevention\u002FTreatment of Acute\u002FChronic Pain in Locally Advanced Head and Neck Cancer","Phase I\u002FII Trial of Gabapentin Plus Ketamine for Prevention and Treatment of Acute and Chronic Pain in Locally Advanced Head and Neck Cancer Patients Undergoing Primary or Adjuvant Chemoradiation","Inclusion Criteria:\n\n* Histologically proven cancer of the head and neck cancer\n* Locally advanced non-metastatic disease (T3N0M0, T4N0M0, T1-4N1-3M0)\n* Planned primary or adjuvant radiation or chemoradiation therapy\n* Willing and able to provide informed consent\n* ECOG PS 0-2\n* Age ≥ 21 years\n* English speaking\n\nExclusion Criteria:\n\n* Currently on gabapentin or ketamine\n* Prior non-tolerance of gabapentin or ketamine\n* Unable to administer ketamine intranasally due to anatomical restrictions\n* History of seizure disorder\n* History of schizophrenia\n* History of increased intracranial pressure\n* Glomerular filtration rate \\\u003C30 mL\u002Fmin\u002F1.73 m2","ALL","21 Years",{"count":19,"type":20},64,"ESTIMATED","INTERVENTIONAL",[23,24],"PHASE1","PHASE2","This is a study to establish a safe and feasible dose for prophylactic use of a combination of gabapentin and ketamine in head and neck cancer patients undergoing chemoradiation.",[27,28],"Head and Neck Cancer","Locally Advanced Head and Neck Carcinoma","RECRUITING","2024-10-17",{"date":32,"type":33},"2024-10-21","ACTUAL",{"date":35,"type":33},"2022-01-24",{"date":37,"type":20},"2026-12-31",{"name":39,"class":40},"Natalie Lockney","OTHER",""]