[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"National Cheng Kung University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":168},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,49,73,95,118,140],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":29,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100531353","effects-of-jing-si-herbal-tea-on-quality-of-life-and-sleep-in-dementia-and-their-caregivers-100531353",false,"NCT06198699","Effects of Jing Si Herbal Tea on Quality of Life and Sleep in Dementia and Their Caregivers","Effects of Jing Si Herbal Tea on Quality of Life and Sleep Among Patients With Dementia and Their Caregivers: A Randomized Controlled Trial","For people with dementia:\n\nInclusion Criteria:\n\n* diagnosis of dementia\n* 50 years or older\n* with sufficient cognition to complete the questionnaires\n* can communicate using Mandarin or Taiwanese\n\nExclusion Criteria:\n\n* with renal function problems\n* not suitable for Jing Si Herbal Tea after evaluation from a psychiatrist\u002Fphysician\n* with the condition of change the commencement of guardianship (or commencement of assistance)\n\nFor caregivers:\n\nInclusion Criteria:\n\n* caregivers of people with dementia for more than half years\n* 20 years or older\n* with sufficient cognition to complete the questionnaires\n* can communicate using Mandarin or Taiwanese\n\nExclusion Criteria:\n\n* with renal function problems\n* not suitable for Jing Si Herbal Tea after evaluation from a psychiatrist\u002Fphysician\n* with the condition of change the commencement of guardianship (or commencement of assistance)","ALL","20 Years",{"count":19,"type":20},400,"ESTIMATED","INTERVENTIONAL",[23],"NA","Jing Si Herbal Tea has been found to be effective in improving health for the conditions of cancers, aging, depression, and sleep. Such evidence has been shown in animal models and clinical research with publications in the international journals. However, empirical evidence regarding the effectiveness of Jing Si Herbal Tea for patients with dementia and their caregivers on their quality of life and psychosocial health remains unclear. Therefore, the present project aims to investigate the feasibility of taking Jing Si Herbal Tea among patients with dementia; then, to investigate if Jing Si Herbal Tea could improve quality of life and psychosocial health for patients with dementia and their caregivers. The project will be three years. The first year will examine the feasibility for the patients with dementia. A total of 100 patients with dementia will be recruited and they will be informed to take the Jing Si Herbal Tea two times per day (one time in the morning and another time in the afternoon). All the participants will be measured for their quality of life and psychosocial health at baseline, three months after baseline, and six months after baseline, to have initial evidence of the improvements in quality of life and psychosocial health without having a control group. The second year will recruit 200 patients with dementia and randomly assign them into a treatment group (taking Jing Si Herbal Tea) and a control group (taking placebo). All the participants will be measured for their quality of life and psychosocial health at baseline, three months after baseline, and six months after baseline, to investigate the strong evidence of Jing Si Herbal Tea on quality of life and psychosocial health. The third year will recruit 200 caregivers of patient with dementia and randomly assign them into a treatment group (taking Jing Si Herbal Tea) and a control group (taking placebo). All the participants will be measured for their quality of life and psychosocial health at baseline, three months after baseline, and six months after baseline, to investigate the strong evidence of Jing Si Herbal Tea on quality of life and psychosocial health.",[26,27,28],"Dementia","Caregiver Burden","Quality of Life",[30,31,32,33,34,35],"dementia","caregiver","quality of life","Jing Si Herbal Tea","psychosocial health","randomized controlled trial","RECRUITING","2026-04-07",{"date":39,"type":40},"2026-04-13","ACTUAL",{"date":42,"type":40},"2025-01-17",{"date":44,"type":20},"2026-12",{"name":46,"class":47},"National Cheng Kung University","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":56,"sex":16,"minAge":57,"maxAge":4,"enrollmentInfo":58,"targetDuration":4,"studyType":21,"phases":60,"briefSummary":61,"conditions":62,"keywords":4,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":65,"lastUpdatePostDateStruct":66,"startDateStruct":68,"completionDateStruct":70,"leadSponsor":72,"locationsCount":48},"100632124","acute-effect-of-different-frequency-of-whole-body-vibration-wbv-on-healthy-and-chronic-obstructive-pulmonary-disease-copd-100632124","NCT07509606","Acute Effect of Different Frequency of Whole Body Vibration (WBV) on Healthy and Chronic Obstructive Pulmonary Disease (COPD)","Acute Effect of Different Frequency of Whole Body Vibration (WBV) on Lung Function, Respiratory Function, Upper Extremity Strength and Flexibility, Cardiac Automatic Function and Quality of Life in Healthy and Moderate and Severe Chronic Obstructive Pulmonary Disease (COPD)","Healthy individuals\n\nInclusion Criteria:\n\n* No prior experience with whole-body vibration therapy or exposure to vibration-related occupations or sports.\n* Aged between 18 and 65 years.\n\nExclusion Criteria:\n\n* Pregnancy.\n* Acute thrombosis.\n* Severe cardiovascular disease.\n* Presence of a cardiac pacemaker.\n* Recent wounds due to injury or surgery.\n* Hip or knee implants.\n* Acute hernia, intervertebral disc degeneration, or spondylolysis.\n* Severe diabetes mellitus.\n* Epilepsy.\n* Recent infection.\n* Severe migraine.\n* Tumor.\n* Recently implanted intrauterine device, metal pins, or metal plates.\n* Kidney stones.\n* Organ failure.\n* Presence of musculoskeletal, respiratory, neurological, cardiovascular conditions, or any form of acute or chronic pain.\n* Participation in other research studies concurrently.\n* Regular exercise habits (engaging in moderate-intensity exercise ≥3 times per week).\n\nCOPD\n\nInclusion Criteria:\n\n* Clinically diagnosed with chronic obstructive pulmonary disease (COPD) and classified as Global Initiative for Chronic Obstructive Lung Disease (GOLD) stage II, III, or IV.\n* No history of hospitalization within the past two months.\n* No participation in any rehabilitation program within the past two months.\n* Able to comply with the exercise training program.\n* Aged 18 years or older.\n\nExclusion Criteria:\n\n* Severe respiratory diseases (e.g., bronchiectasis, pulmonary fibrosis, asthma, or tuberculosis).\n* Current smokers.\n* Hip or knee implants.\n* Severe joint disease or history of lower extremity surgery.\n* History of vitreous hemorrhage.\n* Dependence on supplemental oxygen.\n* Severe alcohol abuse (\\>80 g\u002Fday).\n* Severe malnutrition (BMI \\\u003C 19 kg\u002Fm²).\n* Pregnancy.\n* Acute thrombosis.\n* Presence of a cardiac pacemaker.\n* Recent wounds due to injury or surgery.\n* Acute hernia, intervertebral disc degeneration, or spondylolysis.\n* Severe diabetes mellitus.\n* Epilepsy.\n* Recent infection.\n* Severe migraine.\n* Tumor.\n* Recently implanted intrauterine device, metal pins, or metal plates.\n* Kidney stones.\n* Organ failure.\n* Altered consciousness or inability to comply with assessments.\n* Participation in other research studies concurrently",true,"18 Years",{"count":59,"type":20},102,[23],"Chronic obstructive pulmonary disease (COPD) is an irreversible disorder characterized by persistent airflow limitation and increased lung compliance. It leads to dyspnea, skeletal muscle dysfunction, impaired functional capacity, and reduced quality of life. Physical inactivity is considered a major contributor to symptom deterioration, the development of a vicious cycle, and ultimately increased mortality.\n\nAccording to the American College of Sports Medicine (ACSM), the American Thoracic Society (ATS), and the American Association of Cardiovascular and Pulmonary Rehabilitation (AACVPR), pulmonary rehabilitation should include aerobic and resistance exercise for at least 20 minutes per session, performed three to five times per week for a minimum of 12 weeks. Exercise intensity should be progressively increased to exceed 60% of peak oxygen uptake (VO₂peak), and patients are encouraged to maintain long-term exercise habits. However, there is still no consensus regarding the optimal initial intensity, progression strategy, and exercise duration.\n\nPrevious studies have demonstrated that whole-body vibration (WBV) can improve lower extremity muscle strength, functional capacity, and quality of life in patients with COPD. However, its effects on lung function and the optimal training dose remain unclear. In addition, COPD also affects respiratory muscles, upper extremity strength and flexibility, as well as cardiac autonomic function.\n\nTherefore, the aim of this study is to investigate the effects of different WBV frequencies on lung function, respiratory muscle function, upper extremity strength and flexibility, and cardiac autonomic function, in order to determine the optimal training dose.",[63,64],"Chronic Obstructive Pulmonary Disease (COPD)","Whole Body Vibration","2026-03-29",{"date":67,"type":40},"2026-04-03",{"date":69,"type":40},"2025-04-07",{"date":71,"type":20},"2027-12-31",{"name":46,"class":47},{"id":74,"slug":75,"hasResults":11,"nctId":76,"briefTitle":77,"officialTitle":78,"acronym":4,"eligibilityCriteria":79,"healthyVolunteers":56,"sex":16,"minAge":17,"maxAge":80,"enrollmentInfo":81,"targetDuration":4,"studyType":21,"phases":83,"briefSummary":84,"conditions":85,"keywords":4,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":87,"lastUpdatePostDateStruct":88,"startDateStruct":90,"completionDateStruct":92,"leadSponsor":94,"locationsCount":48},"100615153","exploring-the-effects-of-exercise-combined-with-bfrt-on-healthy-and-patients-with-ckd-100615153","NCT07288905","Exploring the Effects of Exercise Combined With BFRT on Healthy and Patients With CKD","The Feasibility and Effects of Exercise Training Combined With Blood Flow Restriction Training on Exercise Capacity and Exercise Tolerance in Patients With Chronic Kidney Disease","Healthy\n\nInclusion Criteria:\n\n• Aged 20\\~85 years old\n\nExclusion Criteria:\n\n* Severe uncontrolled metabolic diseases (e.g., hyperthyroidism, diabetes, hypertension, hyperlipidemia, etc.)\n* Severe pulmonary or cardiovascular diseases (e.g., pulmonary hypertension, chronic obstructive pulmonary disease (COPD), heart failure, cardiac arrhythmia)\n* Presence of a cardiac pacemaker or a history of myocardial infarction within the past six months\n* Severe musculoskeletal or neuromuscular disorders (e.g., advanced arthritis, limb amputation, post-polio syndrome, Parkinson's disease)\n* Unstable vital signs (e.g., systolic blood pressure ≥180 mmHg, diastolic blood pressure ≥90 mmHg, requiring vasopressors, or resting heart rate \\>100 bpm)\n* Prone to bruising\n* Recent inflection \\\u003C 1 month\n* Pregnancy\n* Kidney function impairment\n* Cancer\n* Simultaneously participating in other research\n\nCKD\n\nInclusion criteria:\n\n* Aged 20\\~85 years old\n* eGFR\\\u003C 90 ml\u002Fmin\u002F1.73 m2 over 3 months\n* Stable condition without worsening in the past 3 months\n* Ability to understand and follow verbal commends and cooperate with an exercise training program\n\nExclusion criteria:\n\n* Severe uncontrolled metabolic diseases (e.g., hyperthyroidism, diabetes, hypertension, hyperlipidemia, etc.)\n* Severe pulmonary or cardiovascular diseases (e.g., pulmonary hypertension, chronic obstructive pulmonary disease (COPD), heart failure, cardiac arrhythmia)\n* Presence of a cardiac pacemaker or a history of myocardial infarction within the past six months\n* Severe musculoskeletal or neuromuscular disorders (e.g., advanced arthritis, limb amputation, post-polio syndrome, Parkinson's disease)\n* Unstable vital signs (e.g., systolic blood pressure ≥180 mmHg, diastolic blood pressure ≥90 mmHg, requiring vasopressors, or resting heart rate \\>100 bpm)\n* Abnormal blood biochemical parameters (e.g., white blood cell count \\\u003C2500\u002Fmm³, hemoglobin \\\u003C8 mg\u002FdL, total bilirubin \\>3 mg\u002FdL, liver enzymes (GOT\u002FAST, GPT\u002FALT) \\>3 times the upper limit of normal, platelet count \\\u003C75,000\u002Fmm³\n* Sensory or motor dysfunctions that affect walking ability\n* Diagnosed systemic diseases under ongoing treatment (e.g., systemic lupus erythematosus, cancer, malignancies).","85 Years",{"count":82,"type":20},120,[23],"Investigate the effects of exercise training on the cardiopulmonary function and exercise capacity in healthy and CKD patients",[86],"Chronic Kidney Disease","2025-12-03",{"date":89,"type":40},"2025-12-17",{"date":91,"type":40},"2025-10-04",{"date":93,"type":20},"2030-12-31",{"name":46,"class":47},{"id":96,"slug":97,"hasResults":11,"nctId":98,"briefTitle":99,"officialTitle":100,"acronym":4,"eligibilityCriteria":101,"healthyVolunteers":11,"sex":16,"minAge":102,"maxAge":80,"enrollmentInfo":103,"targetDuration":4,"studyType":21,"phases":105,"briefSummary":106,"conditions":107,"keywords":109,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":111,"lastUpdatePostDateStruct":112,"startDateStruct":114,"completionDateStruct":116,"leadSponsor":117,"locationsCount":48},"100574235","exploring-the-effects-of-aerobic-exercise-combined-with-bfrt-on-patients-with-copd-100574235","NCT06756646","Exploring the Effects of Aerobic Exercise Combined with BFRT on Patients with COPD","Exploring the Effects of Aerobic Exercise Combined with Blood Flow Restriction Training on Exercise Capacity, Cardiopulmonary Functions, and Quality of Life in Patients with Chronic Obstructive Pulmonary Disease","Inclusion Criteria:\n\n1. COPD classified as levels 2-4.\n2. Stable condition without worsening in the past three months.\n3. No participation in any rehabilitation program within the past six months.\n4. Ability to understand and follow verbal commands and cooperate with an exercise training program.\n\nExclusion Criteria:\n\n1. Unconscious or unable to cooperate with the evaluator.\n2. Hospitalization due to acute illness within the past three months.\n3. Severe joint diseases or history of lower limb surgery.\n4. Severe cardiovascular disease (e.g., presence of a cardiac pacemaker or acute myocardial infarction within the past six months).\n5. Dependence on oxygen supply.","30 Years",{"count":104,"type":20},90,[23],"Investigate the effects of exercise training on the cardiopulmonary function and exercise capacity in COPD patients.",[108],"Chronic Obstructive Pulmonary Disease",[110,108],"Blood flow restriction training","2024-12-25",{"date":113,"type":40},"2025-01-03",{"date":115,"type":40},"2024-11-20",{"date":93,"type":20},{"name":46,"class":47},{"id":119,"slug":120,"hasResults":11,"nctId":121,"briefTitle":122,"officialTitle":123,"acronym":4,"eligibilityCriteria":124,"healthyVolunteers":11,"sex":16,"minAge":125,"maxAge":80,"enrollmentInfo":126,"targetDuration":4,"studyType":21,"phases":127,"briefSummary":128,"conditions":129,"keywords":130,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":132,"lastUpdatePostDateStruct":133,"startDateStruct":135,"completionDateStruct":137,"leadSponsor":139,"locationsCount":48},"100558453","the-effects-of-eccentric-cycling-exercise-program-in-chronic-kidney-disease-patients-100558453","NCT06551311","The Effects of Eccentric Cycling Exercise Program in Chronic Kidney Disease Patients","To Explore Efficacy and Load of Eccentric Cycling Training in Older CKD Patients with or Without Sarcopenia","This study will be conducted in collaboration with the Departments of Nephrology and Geriatric Medicine at National Cheng Kung University Hospital, Taiwan. Participants will be recruited as voluntary subjects from outpatient clinics. The attending physician will assess eligible patients. After the study's purpose and methodology are explained by the research staff and patients consent to participate, block randomization will be used to assign participants into one of three groups randomly. The allocation results will be securely stored by the principal investigator.\n\nInclusion Criteria:\n\n* (1) Clinical diagnosis of CKD\n* (2) eGFR \\\u003C60 ml\u002Fmin\u002F1.73m\\^2 or undergoing routine dialysis\n* (3) Must be able to communicate normally, understand and comply with instructions.\n* (4) Must be able to walk independently.\n\nExclusion Criteria:\n\n* (1) Clinical diagnosis of acute renal failure\n* (2) Hospitalization for acute illness within the past three months\n* (3) Clinical diagnosis of severe joint disease and lower extremity surgery\n* (4) Clinical diagnosis of severe neurological disease\n* (5) Clinical diagnosis of severe cardiovascular disease\n* (6) Unconsciousness or lack of ability to cooperate with the assessment","55 Years",{"count":104,"type":20},[23],"Progress in medical technology, enhancements in environmental cleanliness, and elevated living conditions have notably prolonged the mean life expectancy, resulting in a swift increase in the aging population. The prevalence of Chronic Kidney Disease (CKD) is more pronounced among the elderly in contrast to younger demographics. With the aging of the CKD population, the capacity to autonomously handle daily activities becomes a critical concern. This demographic frequently encounters concurrent health conditions, a decrease in self-care capabilities, general health decline, and diminished quality of life.\n\nRecent studies suggest that physical activity has the potential to enhance cardiovascular health, cardiopulmonary endurance, muscle strength, quality of life, uremic toxin management, and inflammation levels among individuals with CKD. Given that CKD patients often exhibit sedentary behavior and reduced exercise capacity, eccentric cycling exercises may be particularly well-suited for this demographic.\n\nCompared to concentric contractions, eccentric contractions subject the muscles to higher tension. Since muscle growth partially depends on the \"stress exerted on muscle fibers\"-meaning the greater the stress, the more stimulation the muscles receive-training focused on eccentric contractions could provide more stimulation and promote greater muscle growth.\n\nIn recent studies, eccentric cycling has emerged as a feasible and promising aerobic exercise intervention. It can provide a safe and appropriate amount of exercise while relatively reducing joint pressure. This novel combined aerobic and anaerobic exercise method is particularly beneficial for individuals with weaker lower limb muscles, lower joint pressure tolerance, poor metabolic and cardiovascular function, and a tendency to fatigue.",[86],[131,86],"Eccentric Cycling Exercise Training","2024-12-19",{"date":134,"type":40},"2024-12-24",{"date":136,"type":40},"2023-07-01",{"date":138,"type":20},"2026-12-31",{"name":46,"class":47},{"id":141,"slug":142,"hasResults":11,"nctId":143,"briefTitle":144,"officialTitle":145,"acronym":4,"eligibilityCriteria":146,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":147,"targetDuration":4,"studyType":21,"phases":149,"briefSummary":150,"conditions":151,"keywords":155,"overallStatus":159,"whyStopped":4,"lastUpdateSubmitDate":160,"lastUpdatePostDateStruct":161,"startDateStruct":163,"completionDateStruct":165,"leadSponsor":167,"locationsCount":4},"100562233","the-effect-of-a-mobile-application-on-enhancing-pulmonary-rehabilitation-after-lung-cancer-surgery-100562233","NCT06600503","The Effect of a Mobile Application on Enhancing Pulmonary Rehabilitation After Lung Cancer Surgery","The Effectiveness of a Mobile Lung Rehabilitation System on Patient Satisfaction and Lung Function After Lung Cancer Surgery","Inclusion Criteria:\n\n* age over 20 years\n* primary diagnosis of lung cancer at any stage and type\n* referral to lung cancer resection by thoracotomy or videothoracoscopy\n* ability to understand and consent to the trial procedures\n* conscious and cognition intact\n\nExclusion Criteria:\n\n* included adjuvant treatments (chemotherapy or radiotherapy)\n* previous history of thoracic surgery\n* neurological and\u002For musculoskeletal comorbidities\n* visual or hearing impairment\n* acute respiratory illness",{"count":148,"type":20},36,[23],"The goal of this clinical trial is to investigate the effect of a mobile application intervention on postoperative lung rehabilitation. The main purposes of this study are:\n\n1. To understand the effectiveness of the pulmonary rehabilitation mobile application in improving lung function.\n2. To assess the feasibility of the pulmonary rehabilitation mobile application in post-surgery rehabilitation care.\n\nResearchers will compare the intervention group (using the pulmonary rehabilitation mobile application) to the usual care group to determine if the mobile application is effective in lung surgery rehabilitation.\n\nParticipants will join the study immediately after providing informed consent and will continue for up to 7 weeks post-surgery. Participants will be randomly allocated to either the intervention group or the control group. Both groups will receive regular pulmonary rehabilitation during their hospital stay (1 day before surgery and 2 to 3 days after surgery). Researchers will guide participants in the intervention group to use the mobile application for pulmonary rehabilitation exercises throughout the study period. Participants in the usual care group will receive health education and an exercise guide before discharge. Participants will undergo three study assessments: at baseline (within 1 week after enrollment), post-surgery (week 5), and at follow-up (week 8).",[152,153,154],"Pulmonary Rehabilitation","Telerehabilitation","Lung Cancer",[156,157,153,158],"pulmonary rehabilitation","mobile application","Lung cancer","NOT_YET_RECRUITING","2024-09-17",{"date":162,"type":40},"2024-09-19",{"date":164,"type":20},"2024-10-01",{"date":166,"type":20},"2025-12-31",{"name":46,"class":47},""]