[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"National Healthcare Group Polyclinics\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":130},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,50,78,101],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100630340","blood-eosinophil-guided-versus-usual-care-in-the-management-of-mild-to-moderate-asthma-at-primary-care-beam-100630340",false,"NCT07486401","Blood Eosinophil Guided Versus Usual Care In The Management Of Mild To Moderate Asthma at Primary Care (BEAM)","Randomised Controlled Trial Of Blood Eosinophil Guided Versus Usual Care In The Management Of Mild To Moderate Asthma at Primary Care (BEAM)","BEAM","Inclusion Criteria:\n\n1. Singaporeans or Singapore Permanent Residents\n2. Patients aged ≥21 to 65 years old\n3. Physician diagnosed asthma for duration of at least 4 weeks\n4. On or will be initiated on Global Initiative for Asthma (GINA) 2025 step 1-3) treatment\n5. No asthma exacerbations\\* in the preceding 4 weeks before randomisation\n6. Able and willing to attend study appointments approximately every 4-monthly over a 1-year period\n7. Able to provide informed consent\n8. Stable cardiovascular status (i.e. controlled hypertension, no active symptoms of heart disease or arrhythmias) \\*Exacerbations are defined as worsening of asthma symptoms requiring systemic corticosteroid for 3 or more days, emergency department visit, or hospitalization\n\nExclusion Criteria:\n\n1. History of life-threatening asthma requiring intubation or intensive care unit admission\n2. Severe asthma or difficult to treat asthma\n3. Current use of long-term immunosuppression, LTRA receptor antagonist (Montelukast) and Theophylline or long-term oral steroids\n4. Presence of other known causes of eosinophilia besides asthma (e.g. parasitic infection), based on physician's discretion and investigation as per clinical practice and suspicion\n5. Current use of beta-blocking agents including eye-drops\n6. Use of oral, rectal, or parenteral glucocorticoid within 30 days and\u002For depot parenteral glucocorticoid within 12 weeks prior to recruitment\n7. Known diagnosis of Chronic Obstructive Pulmonary Disease, Interstitial lung disease or bronchiectasis\n8. Any significant disease or disorder (eg. Cardiovascular, pulmonary other than asthma, gastrointestinal, hepatic, renal, neurological, musculoskeletal, endocrine, metabolic, malignant, psychiatric, major physical impairment) which, in the opinion of the investigator, may either put the patient at risk because of participation in the study, or may influence the results of the study, or the patient's ability to participate in the study\n9. Current enrolment in other interventional clinical trial for asthma\n10. Female subjects who are pregnant or planning pregnancy during the study period\n11. Planned travel outside of the country for ≥16 consecutive weeks during the study\n12. Investigator's assessment of poor capability of following study instructions or comply with study procedures","ALL","21 Years","65 Years",{"count":21,"type":22},240,"ESTIMATED","INTERVENTIONAL",[25],"NA","The aim of this study is to evaluate usual care versus biomarker-directed care (using blood eosinophil counts) for the management of asthma patients in primary care setting.\n\nThe study hypothesizes that BEC is a valuable biomarker that can guide asthma treatment, and result in reduction in asthma exacerbations, better symptom control and improvement in quality of life compared to usual arm in mild to moderate asthma patients in the primary care setting.\n\nResearchers would compare using blood eosinophil count guided to usual care to see if biomarker-directed asthma treatment and management",[28,29,30],"Asthma Exacerbations","Biomarkers \u002F Blood","Eosinophil Blood Count",[32,33,34,35,36],"Asthma","Mild-moderate Asthma","Blood Biomarkers","Eosinophil","Primary Care","RECRUITING","2026-03-18",{"date":40,"type":41},"2026-03-20","ACTUAL",{"date":43,"type":41},"2025-12-03",{"date":45,"type":22},"2029-12-31",{"name":47,"class":48},"National Healthcare Group Polyclinics","OTHER_GOV",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":54,"acronym":4,"eligibilityCriteria":55,"healthyVolunteers":56,"sex":17,"minAge":57,"maxAge":4,"enrollmentInfo":58,"targetDuration":4,"studyType":23,"phases":60,"briefSummary":61,"conditions":62,"keywords":65,"overallStatus":69,"whyStopped":4,"lastUpdateSubmitDate":70,"lastUpdatePostDateStruct":71,"startDateStruct":73,"completionDateStruct":75,"leadSponsor":77,"locationsCount":49},"100623703","effectiveness-of-a-community-based-intervention-programme-to-promote-well-being-in-older-adults-100623703","NCT07400081","Effectiveness of a Community-based Intervention Programme to Promote Well-being in Older Adults","Inclusion Criteria:\n\n* Aged 55 and above\n* Score of 1-9 on the PHQ-9 questionnaire\n* Able to speak and understand English, Chinese or Malay\n* Able to provide informed consent\n* Be willing to use common technologies (such as phone calls, texting via SMS\u002Fwhatsapp) for communication\n\nExclusion Criteria:\n\n* PHQ-9 score of 0\n* PHQ-9 score of 10 or more\n* Actively being followed up by a mental health professional\n* On psychotropic medication or are undergoing psychotherapy\n* Have other mental disorders or are suicidal\n* Have physical difficulties, cognitive impairment or difficulties with speech, sight and hearing or mobility that may prevent their engagement in activities",true,"55 Years",{"count":59,"type":22},300,[25],"This study is conducted to assess the effectiveness of a community intervention programme on improving well-being, levels of distress, and loneliness in older adults (aged 55 years old and above), who have symptoms of depression.\n\nSocial Service Agencies (SSAs) will conduct focal talks on well-being for the community. As part of the focal talks, the Public Health Questionnaire-9 (PHQ-9) will be conducted. Attendees with a PHQ-9 score of 1-9 will be invited to take part in the study. Up to 300 participants will be recruited and randomised into 2 arms: control arm (150 participants) and intervention arm (150 participants).\n\nParticipants in the intervention arm will undergo 8-week community intervention programme which includes 4 sessions on well-being and continuous follow-up with a Health Companion. Participants in the control arm will be offered to join a programme conducted by the SSAs 8 weeks after recruitment into the study. The programmes offered to the control group are independent of the study.",[63,64],"Well-being\u002FQuality of Life","Mental Health",[66,67,68,64],"Community-based intervention","Well-being","Older adults","NOT_YET_RECRUITING","2026-02-10",{"date":72,"type":41},"2026-02-13",{"date":74,"type":22},"2026-03",{"date":76,"type":22},"2028-12",{"name":47,"class":48},{"id":79,"slug":80,"hasResults":11,"nctId":81,"briefTitle":82,"officialTitle":82,"acronym":4,"eligibilityCriteria":83,"healthyVolunteers":56,"sex":84,"minAge":85,"maxAge":86,"enrollmentInfo":87,"targetDuration":4,"studyType":23,"phases":89,"briefSummary":90,"conditions":91,"keywords":4,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":49},"100556675","evaluating-the-impact-of-different-methods-of-hpv-dna-testing-for-cervical-cancer-screening-in-primary-care-settings-100556675","NCT06528184","Evaluating the Impact of Different Methods of HPV DNA Testing for Cervical Cancer Screening in Primary Care Settings","Inclusion Criteria:\n\n* 30-69 years old female Singapore citizens\n* Due for cervical cancer screening\n* Engaged in sexual intercourse before\n* Able to give informed consent\n* Able to read and communicate in English, Chinese or Malay\n\nExclusion Criteria:\n\n* Virgo intacta\n* Pregnancy\n* History of cervical cancer, precancerous cervical lesions and total hysterectomy","FEMALE","30 Years","69 Years",{"count":88,"type":22},650,[25],"Primary objective of the study is to determine the extent that offering of self-sampling in addition to clinician-sampling Human Papillomavirus (HPV) DNA testing will increase detection of HPV DNA through an increase in uptake rates of cervical cancer screening as compared to offering clinician-sampling HPV DNA testing alone.\n\nThe hypothesis is that offering additional self-sampling will increase the detection of high-risk HPV DNA by at least 7.7%.",[92],"Uterine Cervical Neoplasms","2025-02-05",{"date":95,"type":41},"2025-02-10",{"date":97,"type":41},"2024-08-05",{"date":99,"type":22},"2026-12",{"name":47,"class":48},{"id":102,"slug":103,"hasResults":11,"nctId":104,"briefTitle":105,"officialTitle":106,"acronym":107,"eligibilityCriteria":108,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":109,"enrollmentInfo":110,"targetDuration":4,"studyType":23,"phases":112,"briefSummary":113,"conditions":114,"keywords":117,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":121,"lastUpdatePostDateStruct":122,"startDateStruct":124,"completionDateStruct":126,"leadSponsor":128,"locationsCount":129},"100550207","the-pact-patient-activation-through-conversations-study-100550207","NCT06444074","The PACT (Patient Activation Through Conversations) Study","The PACT (Patient Activation Through Conversations) Study - A Cluster Randomised Trial of a Health Coach-led Patient Activation Program in Type 2 Diabetes.","PACT","Inclusion Criteria:\n\n* Individuals with a diagnosis of Type 2 Diabetes Mellitus who are enrolled in Teamlets in NHGP\n* Age between 21 to 64 years old\n* HbA1c level of more than 8% in the last 6 months\n\nExclusion Criteria:\n\n* History of acute coronary syndrome in the past 3 months\n* History of stroke or transient ischaemic attacks in the past 3 months\n* History of end stage organ failure (liver cirrhosis, cardiac failure, latest eGFR \\\u003C30 mL\u002Fmin\u002F1.73m2 in the last 6 months)\n* Cancer requiring treatment in the past 5 years.\n* Active psychiatrist follow up\n* Social issues that are significant enough for follow-up or referral with a medical social worker within the last 12 months\n* Women who are pregnant or breastfeeding\n* Patients who are enrolled in other current diabetes-related interventional studies\n* Inability to provide written consent for the study protocol and able to commit to the study duration.","64 Years",{"count":111,"type":22},432,[25],"The PACT Study is a cluster randomised trial of a health coach-led patient activation program in type 2 diabetes. The goal of this clinical trial is to evaluate the effectiveness of a health coaching intervention (PACT program) led by Care Coaches (trained lay persons), in adult participants with sub-optimally controlled Diabetes Mellitus, as compared to participants undergoing routine care for diabetes (Usual Care).\n\nThe primary outcome of interest is change in Glycated Haemoglobin (HbA1c) levels over 3 months, 6 months and 12 months. Secondary outcomes include changes in blood pressure, low-density lipoprotein-cholesterol (LDL-C) levels, body mass index (BMI), self-reported diabetes self-care behaviours, self-efficacy, health-related quality of life, and diabetes-related distress, over 3, 6 and 12 months.\n\nParticipants in the Intervention arm will undergo the PACT Program, which is a 3-month long health coaching program led by a care coach. Participants review their motivators, health parameters, self-care behaviours, and set goals for improving their diabetes using a PACT report. Subsequently, they will receive fortnightly motivational and problem solving support via telephone or WhatsApp messaging over a 3-month duration, and will return to routine care after 3 months. Participants in the Usual Care arm will have routine care of their diabetes treatment.",[115,116],"Diabetes Mellitus","Diabetes Mellitus, Type 2",[115,118,119,120],"Health Coaching","Endocrinology","Lifestyle Intervention","2024-06-11",{"date":123,"type":41},"2024-06-13",{"date":125,"type":41},"2024-04-22",{"date":127,"type":22},"2028-04-22",{"name":47,"class":48},3,""]