[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"National Taipei University of Nursing and Health Sciences\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":424},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,15,0,[8,42,74,101,129,157,192,214,237,263,283,310,336,364,391],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100645120","a-theory-based-fluid-self-management-program-100645120",false,"NCT07677605","A Theory-based Fluid Self-management Program","Effects of Self-Management Program on Interdialytic Weight Gain Control in Hemodialysis Patients: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Receiving maintenance hemodialysis for ≥ 3 months\n* Undergoing hemodialysis two times per week on a regular schedule\n* Possession of a smartphone with active WhatsApp use\n* Ability to read and understand Indonesian, with support provided in Javanese where necessary.\n* Provision of written informed consent\n\nExclusion Criteria:\n\n* Severe cognitive impairment or diagnosed psychiatric disorders affecting comprehension or participation, as documented in the medical record.\n* Severe visual, hearing, or communication impairments not corrected by assistive devices\n* Current hospitalisation or unstable medical condition\n* Planned kidney transplantation or dialysis modality change during the study period\n* Participation in another interventional study related to fluid management or self-management\n* Inability to engage with the WhatsApp Channel follow-up","ALL","18 Years",{"count":19,"type":20},160,"ESTIMATED","INTERVENTIONAL",[23],"NA","This study aims to evaluate the efficacy of an intervention guided by the IFSMT, in which structured education and digitally delivered reinforcement strategies are designed to enhance self-management processes, including knowledge and beliefs, self-regulation skills, and social facilitation, among patients undergoing maintenance hemodialysis. The intervention, delivered via a mobile platform three times daily over two months, seeks to improve fluid control adherence and hemodialysis self-management behaviours, and to reduce interdialytic weight gain and stabilise pre-hemodialysis mean arterial pressure, compared with standard education alone.",[26],"Hemodialysis Patient",[28,29],"Fluid-Self Management Program","Interdialytic Weight Gain Control","NOT_YET_RECRUITING","2026-06-24",{"date":33,"type":34},"2026-07-01","ACTUAL",{"date":33,"type":20},{"date":37,"type":20},"2027-02-28",{"name":39,"class":40},"National Taipei University of Nursing and Health Sciences","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":49,"minAge":17,"maxAge":4,"enrollmentInfo":50,"targetDuration":4,"studyType":21,"phases":52,"briefSummary":53,"conditions":54,"keywords":58,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":66,"lastUpdatePostDateStruct":67,"startDateStruct":69,"completionDateStruct":71,"leadSponsor":73,"locationsCount":41},"100644420","integrated-intrapartum-supportive-care-and-pushing-strategies-in-women-receiving-low-dose-epidural-analgesia-100644420","NCT07663500","Integrated Intrapartum Supportive Care and Pushing Strategies in Women Receiving Low-Dose Epidural Analgesia","Integrated Intrapartum Supportive Care Combined With Different Pushing Strategies Among Women Receiving Low-Dose Epidural Analgesia: A Three-Arm Non-Randomized Quasi-Experimental Study","Inclusion Criteria:low-risk pregnant women aged 18 years or older with a singleton, term pregnancy (37-42 weeks), spontaneous labor onset, and planning to receive low-dose epidural analgesia.\n\nExclusion Criteria: Exclusion Criteria: multiple gestation, non-cephalic presentation, known major fetal anomalies, planned cesarean birth, contraindications to vaginal birth, contraindications to maternal mobility or epidural analgesia, or inability to provide informed consent.","FEMALE",{"count":51,"type":20},159,[23],"This prospective, three-arm, non-randomized quasi-experimental study aims to evaluate integrated intrapartum supportive care combined with different pushing strategies among women at 37-42 weeks of gestation who receive low-dose epidural analgesia. Participants receive integrated intrapartum supportive care combined with spontaneous pushing, integrated intrapartum supportive care combined with immediate pushing, or routine intrapartum care combined with immediate pushing. The primary outcomes are the durations of the first and second stages of labor. Secondary outcomes include mode of birth, obstetric interventions, maternal outcomes, and neonatal outcomes.",[55,56,57],"Labor, Obstetric","Epidural Analgesia, Obstetric","Labor Duration",[59,60,61,62,63,64],"Integrated intrapartum supportive care","Spontaneous pushing","Immediate pushing","Low-dose epidural analgesia","Maternal mobility","Labor progression","RECRUITING","2026-06-17",{"date":68,"type":34},"2026-06-23",{"date":70,"type":34},"2025-06-10",{"date":72,"type":20},"2026-07-31",{"name":39,"class":40},{"id":75,"slug":76,"hasResults":11,"nctId":77,"briefTitle":78,"officialTitle":79,"acronym":4,"eligibilityCriteria":80,"healthyVolunteers":11,"sex":16,"minAge":81,"maxAge":82,"enrollmentInfo":83,"targetDuration":4,"studyType":21,"phases":85,"briefSummary":86,"conditions":87,"keywords":89,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":93,"lastUpdatePostDateStruct":94,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":99,"locationsCount":100},"100608048","dyadic-co-learning-intervention-for-patients-with-prostate-cancer-and-their-spouses-100608048","NCT07196488","Dyadic Co-learning Intervention for Patients With Prostate Cancer and Their Spouses","Development and Exploring the Efficacy of a Dyadic Co-learning Intervention for Patients With Prostate Cancer and Their Spouses","Inclusion Criteria:\n\nFor Patients:\n\n1. Diagnosed with prostate cancer by a board-certified urologist.\n2. Has either decided on a treatment plan or completed treatment within the past two years.\n3. Has an Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1.\n\nFor Spouses:\n\n1. Must be a cohabiting spouse of the prostate cancer patient and aged 20 years or older.\n2. Must have a Barthel Index score of 91 or above, indicating good functional independence.\n\nExclusion Criteria:\n\nEither the patient or the spouse will be excluded if:\n\n1. Diagnosed with another type of cancer.\n2. Diagnosed with cognitive impairment or a psychiatric disorder, such as dementia, depression, or anxiety.","20 Years","90 Years",{"count":84,"type":20},60,[23],"This study aims to help patients with prostate cancer and their spouses cope better with the challenges of cancer by learning and supporting each other together. The investigators will test an 8-week \"Dyadic Co-learning Intervention,\" which includes weekly learning topics, a mobile app, and professional support. The goal is to improve their physical symptoms, emotional well-being, and resilience.\n\nParticipants will be randomly assigned to one of two groups. One group will receive regular care, while the other group will receive regular care plus the new co-learning program. The investigators will ask both patients and their spouses to complete questionnaires at the beginning of the study, and again at 10 and 16 weeks, to understand how the program affects their health and well-being.",[88],"Prostate Cancer (Adenocarcinoma)",[90,91,92],"Prostate cancer","emotional well-being","physical symptoms","2026-05-16",{"date":95,"type":34},"2026-05-19",{"date":97,"type":34},"2025-10-13",{"date":72,"type":20},{"name":39,"class":40},2,{"id":102,"slug":103,"hasResults":11,"nctId":104,"briefTitle":105,"officialTitle":106,"acronym":107,"eligibilityCriteria":108,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":109,"targetDuration":4,"studyType":21,"phases":111,"briefSummary":112,"conditions":113,"keywords":115,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":121,"lastUpdatePostDateStruct":122,"startDateStruct":124,"completionDateStruct":126,"leadSponsor":128,"locationsCount":4},"100634679","cancer-survivors-fear-of-cancer-recurrence-100634679","NCT07542821","Cancer Survivors' Fear of Cancer Recurrence","Development and Evaluation of An Innovative Program in Mental Health Promotion","MHPII","Inclusion Criteria:\n\n* stage I, II, III breast, head and neck, colo-rectal, proste cancer and completion of primary cancer treatment\n* report of fear of cancer recurrence\n* able to read and listen in Manderin and without a cognitive defect\n\nExclusion Criteria:\n\n* diagnosed with severe mental illness\n* difficult to communicate in Manderin",{"count":110,"type":20},150,[23],"The purpose of this study is to develop and evaluate the tailored support for the fear of cancer recurrence in breast, head and neck, colon-rectal or prostate cancer survivors. Based on screening for fear of cancer recurrence, different levels of supportive care will be provided, starting with the oncology nurses' health education and information for those having a lower level of concern. Those who have medium or higher levels of concerns will be randomized to receive \"stepping up\" either a \"ConquerFear psychological cognitive training\" or a \"healthy lifestyle - individualized exercise and nutrition guidance\".",[114],"Fear of Cacer Recurrence in Cancer Survivorws",[116,117,118,119,120],"Fear of cancer recurrence","cancer survivor","psychosoical support","ConquerFear","Healthy life style","2026-04-14",{"date":123,"type":34},"2026-04-21",{"date":125,"type":20},"2026-04-15",{"date":127,"type":20},"2028-11-30",{"name":39,"class":40},{"id":130,"slug":131,"hasResults":11,"nctId":132,"briefTitle":133,"officialTitle":134,"acronym":4,"eligibilityCriteria":135,"healthyVolunteers":136,"sex":16,"minAge":81,"maxAge":137,"enrollmentInfo":138,"targetDuration":4,"studyType":21,"phases":140,"briefSummary":141,"conditions":142,"keywords":144,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":149,"lastUpdatePostDateStruct":150,"startDateStruct":152,"completionDateStruct":154,"leadSponsor":156,"locationsCount":41},"100611679","information-assisted-intervention-for-potential-living-kidney-donors-100611679","NCT07243717","Information-Assisted Intervention for Potential Living Kidney Donors","The Effectiveness of an Information-Assisted Intervention for Potential Living Kidney Donors","Inclusion Criteria:\n\n* Willing to undergo evaluation for living kidney donation\n* Owns a smartphone or tablet with internet access\n* Able and willing to participate in the study and provide written informed consent\n\nExclusion Criteria:\n\n\\- Deemed unsuitable for kidney donation after evaluation by a transplant specialist",true,"70 Years",{"count":139,"type":20},45,[23],"This study aims to evaluate the effectiveness of an information-assisted intervention in enhancing knowledge, decision self-efficacy, and reducing decisional conflict among potential living kidney donors. Using a one-group pretest-posttest design, participants will be recruited from the urology and kidney transplant outpatient clinics of two hospitals in northern Taiwan. After providing informed consent and completing a baseline questionnaire (T0), participants will receive a four-week information-assisted intervention in addition to routine care, with follow-up assessments at 4 weeks (T1) and 8 weeks (T2). Data will be collected using structured questionnaires assessing decisional conflict, decision self-efficacy, knowledge, positive thinking, family resilience, and satisfaction with the intervention.",[143],"Transplant Donation",[145,146,147,148],"Potential Living Kidney Donors","knowledge","decision self-efficacy","decisional conflict","2026-04-06",{"date":151,"type":34},"2026-04-08",{"date":153,"type":34},"2026-03-27",{"date":155,"type":20},"2027-07-31",{"name":39,"class":40},{"id":158,"slug":159,"hasResults":11,"nctId":160,"briefTitle":161,"officialTitle":161,"acronym":4,"eligibilityCriteria":162,"healthyVolunteers":136,"sex":16,"minAge":163,"maxAge":4,"enrollmentInfo":164,"targetDuration":4,"studyType":21,"phases":166,"briefSummary":167,"conditions":168,"keywords":174,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":185,"lastUpdatePostDateStruct":186,"startDateStruct":188,"completionDateStruct":190,"leadSponsor":191,"locationsCount":41},"100617215","the-efficacy-of-a-technology-assisted-block-training-program-on-cognitive-function-hand-dexterity-and-grip-strength-in-community-dwelling-older-adults-a-mixed-methods-research-100617215","NCT07315724","The Efficacy of a Technology-Assisted Block Training Program on Cognitive Function, Hand Dexterity, and Grip Strength in Community-Dwelling Older Adults: A Mixed-Methods Research","Inclusion Criteria:\n\n1. Adults aged 65 and older\n2. Mentally alert and able to communicate\n3. Willing to participate in this study\n\nExclusion Criteria:\n\n1. Diagnosed with dementia by a physician\n2. Severe sensory or communication impairment\n3. Hand function impairment that prevents manipulation of building blocks","65 Years",{"count":165,"type":20},40,[23],"Block-building activities represent a promising tool for enhancing cognitive and hand function in older adults. When integrated with technological support, they offer personalized training advantages; however, their comprehensive effectiveness requires empirical validation. This study aimed to develop and evaluate a \"Technology-Assisted Block Training Program\" to explore its effects on cognitive function, hand grip strength, dexterity, and quality of life among community-dwelling older adults, while examining participants' subjective experiences.",[169,170,171,172,173],"Community-Dwelling Older Adults","Aging","Cognitive Decline","Hand Dexterity","Muscle Strength",[175,176,177,178,179,180,181,182,183,184],"Technology-assisted block training program","Block-building activities","Cognitive function","Hand dexterity","Grip strength","Older adults","Mental rotation","Mixed-methods research","Spatial cognition","Quality of life","2025-12-23",{"date":187,"type":34},"2026-01-02",{"date":189,"type":34},"2025-03-28",{"date":153,"type":20},{"name":39,"class":40},{"id":193,"slug":194,"hasResults":11,"nctId":195,"briefTitle":196,"officialTitle":197,"acronym":4,"eligibilityCriteria":198,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":82,"enrollmentInfo":199,"targetDuration":4,"studyType":21,"phases":201,"briefSummary":202,"conditions":203,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":207,"lastUpdatePostDateStruct":208,"startDateStruct":210,"completionDateStruct":212,"leadSponsor":213,"locationsCount":41},"100600897","essential-oil-assisted-respiratory-training-in-type-2-diabetic-patients-with-lung-infections-100600897","NCT07103460","Essential Oil-Assisted Respiratory Training in Type 2 Diabetic Patients With Lung Infections","The Effect of Essential Oil Diffusion Combined With Respiratory Training on the Respiratory Function of Patients With Acute Pulmonary Infections and Type 2 Diabetes","Inclusion Criteria:\n\nI. Currently hospitalized due to pulmonary infection (ICD-10 codes: J00.x to J22.x).\n\nII. Diagnosed with type 2 diabetes mellitus (ICD-10 codes: E10.x or E11.x). III. Aged between 18 and 90 years. IV. Able to communicate verbally or non-verbally and understand Mandarin or Taiwanese.\n\nV. Willing to participate in the study and consent to group assignment.\n\nExclusion Criteria:\n\nI. Modified Rankin Scale (mRS) score ≥ 5, indicating severe functional impairment.\n\nII. Diagnosed with dementia (unable to comprehend or follow intervention instructions).\n\nIII. Presence of acute psychiatric symptoms that impair communication. IV. Individuals with high litigation risk. V. Diagnosed with chronic obstructive pulmonary disease (COPD) or any other chronic respiratory diseases.\n\nVI. Diagnosed with glucose-6-phosphate dehydrogenase (G6PD) deficiency (ICD-10 codes: D55.x, D74-75.x).",{"count":200,"type":20},100,[23],"Previous studies have shown that baseline pulmonary function in patients with type 2 diabetes mellitus (T2DM) is approximately 8% to 10% lower than in healthy individuals. Under similar infection conditions, respiratory function impairment is more pronounced in T2DM patients. Therefore, this project aims to explore the effects of incentive spirometry (IS) respiratory training combined with an essential oil diffusion device on improving respiratory function in T2DM patients. Over next two years, this study will utilize data from medical history, blood examination, cardiopulmonary endurance evaluations, subjective respiratory symptom assessments, and pulmonary function analyses to demonstrate the improving effect of the intervention in the patients with T2DM and pulmonary infection. In the first year, the study will focus on assessing the improvement in respiratory function among T2DM patients with concurrent pulmonary infections following IS respiratory training. In the second year, three commonly used essential oils (wintergreen, peppermint, and eucalyptus) will be integrated into IS respiratory training. The goal is to enhance patient comfort during training while improving the effectiveness of respiratory training and investigating the mechanisms and effects of different essential oils. The expected outcomes of this study include demonstrating that IS respiratory training combined with an essential oil diffusion device developed by our research team, could more effectively improve the respiratory function of T2DM patients with pulmonary infections. Building on this foundation, the project aims to increase patient comfort during training sessions by incorporating three commonly available essential oils-wintergreen, peppermint, and eucalyptus. This approach is expected to enhance patient acceptance of respiratory training interventions, laying a solid foundation for clinical promotion. Additionally, the study will analyze the differential effects of these essential oils on respiratory function improvement, providing a cornerstone for future clinical research in the fields of chemistry,",[204,205,206],"Type 2 Diabetes Mellitus (T2DM)","Pulmonary Infections","Pneumonia","2025-08-04",{"date":209,"type":34},"2025-08-05",{"date":211,"type":20},"2025-07-25",{"date":155,"type":20},{"name":39,"class":40},{"id":215,"slug":216,"hasResults":11,"nctId":217,"briefTitle":218,"officialTitle":219,"acronym":4,"eligibilityCriteria":220,"healthyVolunteers":136,"sex":221,"minAge":17,"maxAge":222,"enrollmentInfo":223,"targetDuration":4,"studyType":21,"phases":225,"briefSummary":226,"conditions":227,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":229,"lastUpdatePostDateStruct":230,"startDateStruct":232,"completionDateStruct":234,"leadSponsor":236,"locationsCount":41},"100588968","evaluate-the-effectiveness-of-the-mobile-instant-messaging-intervention-100588968","NCT06948305","Evaluate the Effectiveness of the Mobile Instant Messaging Intervention","Exploring the Care Needs of Spouses of Gynecological Cancer Patients and Evaluating the Development of Care Plans","Inclusion Criteria:\n\n1. Age 18 or older, with a diagnosis of gynecological cancer (including cancers of the cervix, endometrium, fallopian tubes, ovaries, uterus, or vagina), and whose spouse has not been diagnosed with any other type of cancer;\n2. The spouse has undergone cancer treatment, including surgery, chemotherapy, or radiotherapy;\n3. Clear consciousness and ability to communicate in Mandarin or Taiwanese;\n4. Willingness to participate in the study after being informed of the study purpose and procedures.\n\nExclusion Criteria:\n\nIndividuals with psychiatric disorders.","MALE","80 Years",{"count":224,"type":20},70,[23],"This study explores the caregiving needs of male spouses and develops an instant messaging software intervention to provide effective support. The goal is to help male spouses better adjust to their caregiving roles, reduce psychological stress and emotional distress, and improve overall health.\n\nA randomized controlled trial will be conducted to evaluate the effectiveness of the mobile instant messaging intervention, analyzing its impact on reducing psychological distress and improving the quality of life of male spouses.",[228],"Gynecological Cancer","2025-04-28",{"date":231,"type":34},"2025-04-29",{"date":233,"type":20},"2025-08-01",{"date":235,"type":20},"2028-07-31",{"name":39,"class":40},{"id":238,"slug":239,"hasResults":11,"nctId":240,"briefTitle":241,"officialTitle":242,"acronym":4,"eligibilityCriteria":243,"healthyVolunteers":11,"sex":16,"minAge":163,"maxAge":4,"enrollmentInfo":244,"targetDuration":4,"studyType":21,"phases":245,"briefSummary":246,"conditions":247,"keywords":249,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":255,"lastUpdatePostDateStruct":256,"startDateStruct":258,"completionDateStruct":260,"leadSponsor":262,"locationsCount":41},"100577372","the-effect-of-dual-tasks-of-digital-technology-on-cognitive-function-and-physical-activity-in-the-older-adults-with-cognitive-frailty-100577372","NCT06797440","The Effect of Dual Tasks of Digital Technology on Cognitive Function and Physical Activity in the Older Adults With Cognitive Frailty","The Effect of Dual Tasks of Digital Technology on Cognitive Function and Physical Activity in the Older Adults With Cognitive Frailty - A Randomized Controlled Trial","Inclusion Criteria:\n\n* Aged 65 years or older\n* Subjective cognitive decline (measured by SMC with a score of at least 1 point) or mild cognitive impairment (measured by MoCA-T with a score of ≤25 points)\n* Possessing characteristics of physiological frailty (meeting at least one of the above items as measured by FFI)\n\nExclusion Criteria:\n\n* Diagnosed with Alzheimer's disease or other types of dementia\n* Suffering from musculoskeletal diseases and severe mental illness that make it impossible to perform cognitive and motor tasks",{"count":200,"type":20},[23],"Background: Cognitive frailty is a state that combines physical weakness and cognitive impairment. As age increases, the prevalence rate also increases. Older adults with cognitive frailty are prone to falls, limited or degraded physical functions, and are at high risk of becoming disabled. It is an essential predictor of dementia and mortality. There are currently very few randomized controlled trial studies on cognitive frailty abroad. Although there are many related studies on senile frailty in Taiwan, most studies examine cognitive function and physical frailty separately. Since cognitive frailty is reversible, early intervention can delay or prevent the occurrence of cognitive frailty. Therefore, cognitive-motor dual tasks are introduced. For more information, see the effectiveness of dual-tasking in cases of cognitive decline.\n\nPurpose: Goal is to not only explore the feasibility of a motor-cognition dual-task program for elderly individuals with cognitive frailty but also to compare its impact on cognitive and physical function with existing training programs. By doing so, the purpose of this study will be to provide practical insights that can inform the development of effective interventions for this vulnerable population.\n\nMethods: A randomized clinical trial was used to explore the effectiveness of a dual-task intervention program on cognitive function and physical activity in older adults with cognitive frailty. Eligible subjects were recruited through convenience sampling and randomly assigned to two groups. The experimental group used Nintendo Switch to perform dual tasks of motor cognition, while the control group performed regular activities. Twice a week, 60 minutes each time, for eight weeks of training. Both groups completed basic information (demographics, disease characteristics, and lifestyle), cognitive function measurements, and physical activity function measurements in the pre-test (T0) in the 4th week (T1) and 8th week (T2). Cognitive function measurements and physical activity function measurements were performed again. Using SPSS 29.0 as a statistical tool, independent sample t-test and Chi-square test were used to detect the demographic variables, disease treatment variables, living habits, cognitive functions, and physical effects of the two groups-homogeneity of activities. A generalized estimating equation (GEE) was used as a statistical method to process and analyze repeated measurement data. The effects of the inter-group and time interaction on the two groups' cognitive function and physical activity were studied differently.\n\nExpected research results: This study is expected to construct a suitable dual-task program to introduce the role of physical and cognitive function in this group and explore its effectiveness.",[248],"Cognitive Frailty",[248,250,251,252,253,254],"Dual task","Digital technology","Nintendo Switch","Physical activity","Cognition funtion","2025-03-31",{"date":257,"type":34},"2025-04-03",{"date":259,"type":20},"2025-04-30",{"date":261,"type":20},"2026-06-30",{"name":39,"class":40},{"id":264,"slug":265,"hasResults":11,"nctId":266,"briefTitle":267,"officialTitle":268,"acronym":4,"eligibilityCriteria":269,"healthyVolunteers":11,"sex":16,"minAge":163,"maxAge":4,"enrollmentInfo":270,"targetDuration":4,"studyType":21,"phases":272,"briefSummary":273,"conditions":274,"keywords":4,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":276,"lastUpdatePostDateStruct":277,"startDateStruct":278,"completionDateStruct":280,"leadSponsor":282,"locationsCount":41},"100583338","the-effects-of-intelligent-intervention-programs-on-hospitalized-elderly-people-with-frailty-100583338","NCT06875024","The Effects of Intelligent Intervention Programs on Hospitalized Elderly People With Frailty.","A Series of Studies on Influencing Factors and Intelligent Intervention Programs for Hospitalized Elderly People With Frailty","Inclusion Criteria:\n\n* Hospitalized patients aged 65 years and older. (、\n* Admitted to the nephrology department or undergoing dialysis.\n* Conscious, able to express themselves independently, follow instructions, and communicate in Mandarin or Taiwanese.\n* Expected hospital stay of at least six days.\n* Assessed using the Physical Activity Readiness Questionnaire for Everyone (PAR-Q+) and deemed to have no immediate risk for exercise participation, with normal capability for physical activity.\n\nExclusion Criteria:\n\n* Severe visual or hearing impairments that hinder communication or assessments.\n* Significant cognitive impairment, defined as a Montreal Cognitive Assessment (MoCA) score \\\u003C 24.\n* Patients who do not consent to participate in the study.\n* Individuals unable to personally complete the consent form.\n* Patients receiving palliative care.\n* Regular participants in rehabilitation therapy.\n* Charlson Comorbidity Index (CCI) score ≥ 5.",{"count":271,"type":20},156,[23],"Background: As the aging population grows, hospitalized elderly individuals with frailty have become a major concern. Frailty is a complex syndrome linked to aging, marked by dependency and vulnerability. Elderly patients often face chronic diseases, making them more susceptible to frailty. Studies show frailty prevalence in hospitalized elderly patients is 88.7%, and 75.3% among kidney disease patients. Frailty is associated with advanced age, female gender, low body mass index, comorbidities, and poor nutrition, increasing the risks of falls, hospitalization, and mortality. Frail kidney disease patients face worse outcomes. However, frailty is reversible with early intervention. Current treatments, based on comprehensive geriatric assessment (CGA), require significant resources. This study aims to explore frailty prevention and care through research and intervention development.\n\nPurpose: To explore the effectiveness of an intelligent intervention program in improving frailty among hospitalized elderly individuals.\n\nMethods: An experimental research design was adopted. A total of 156 hospitalized elderly patients with kidney disease who met the inclusion criteria were recruited through convenience sampling. Participants were randomly assigned to either the experimental group (n = 78) or the control group (n = 78). The experimental group received a 12-week intelligent intervention program, while the control group received routine care.Subsequently, data on frailty level, daily living function 30 days after discharge, and unexpected readmission rate 30 days after discharge will be collected by researchers and analyzed using SPSS 22.0, including chi-square tests, repeated measures ANOVA, and Generalized Estimating Equations (GEE) for intra-group and inter-group comparisons of each outcome variable.\n\nExpected research results: This study aims to understand the current status and influencing factors of frailty among hospitalized elderly patients with kidney disease and to develop an intelligent intervention program. The goal is to provide clinical nursing staff with a frailty care strategy for hospitalized patients, effectively reducing frailty among elderly inpatients, improving their daily functional ability after discharge, and decreasing hospital readmission rates.\n\nCondition or disease: frailty Intervention\u002Ftreatment: intelligent intervention program",[275],"Frailty in Older Adults","2025-03-29",{"date":257,"type":34},{"date":279,"type":20},"2025-04-15",{"date":281,"type":20},"2026-12-31",{"name":39,"class":40},{"id":284,"slug":285,"hasResults":11,"nctId":286,"briefTitle":287,"officialTitle":287,"acronym":4,"eligibilityCriteria":288,"healthyVolunteers":136,"sex":16,"minAge":163,"maxAge":4,"enrollmentInfo":289,"targetDuration":4,"studyType":21,"phases":291,"briefSummary":292,"conditions":293,"keywords":298,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":302,"lastUpdatePostDateStruct":303,"startDateStruct":305,"completionDateStruct":307,"leadSponsor":309,"locationsCount":41},"100577400","effectiveness-of-information-technology-assisted-horticultural-therapy-program-on-heart-rate-variability-stress-depression-and-happiness-among-older-adults-resident-in-long-term-care-facilities-100577400","NCT06797804","Effectiveness of Information Technology-Assisted Horticultural Therapy Program on Heart Rate Variability, Stress, Depression and Happiness Among Older Adults Resident in Long-Term Care Facilities","Inclusion Criteria:\n\n1. Agree to participate in this study\n2. Elderly persons aged 65 and above living in long-term care facilities\n3. Live in long-term care facilities for at least three months\n4. No gender restrictions\n5. Be aware, able to communicate in Mandarin and Taiwanese, and be able to express opinions\n6. The upper limbs can move freely and there is no disease that causes tremors in the hands (such as Parkinson's disease, hepatic encephalopathy, etc.)\n\nExclusion Criteria:\n\n1. Has participated in gardening-related activities within one month of receiving the case\n2. Those diagnosed with terminal illness or whose health condition is rapidly deteriorating\n3. Those suffering from Parkinson's disease, serious heart disease, dementia, mental illness (e.g. schizophrenia, bipolar disorder, etc.)\n4. Mini-Mental State Examination (MMSE) with cognitive impairment (MMSE scores below 16 points for individuals with no formal education, below 21 points for those with elementary education, and below 24 points for those with junior high school education or higher.)\n5. Those who are unable to participate in the event due to severe speech, vision or hearing impairment",{"count":290,"type":20},76,[23],"This study aims to address existing research gaps by investigating the effects of technology-assisted horticultural therapy on stress, depression, and happiness among older adults residing in long-term care facilities. By examining the modulation of the autonomic nervous system, the findings will provide a foundation for developing comprehensive health promotion programs that integrate traditional therapeutic practices with modern technology to enhance the well-being of the aging population.",[294,295,296,297],"Heart Rate Variability","Stress","Depression","Happiness",[299,180,300,301],"Horticultural Therapy","Information and communication technology","Mental health","2025-01-21",{"date":304,"type":34},"2025-01-28",{"date":306,"type":34},"2024-11-14",{"date":308,"type":20},"2026-10-08",{"name":39,"class":40},{"id":311,"slug":312,"hasResults":11,"nctId":313,"briefTitle":314,"officialTitle":315,"acronym":4,"eligibilityCriteria":316,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":222,"enrollmentInfo":317,"targetDuration":4,"studyType":21,"phases":319,"briefSummary":320,"conditions":321,"keywords":324,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":329,"lastUpdatePostDateStruct":330,"startDateStruct":332,"completionDateStruct":334,"leadSponsor":335,"locationsCount":41},"100508739","transcutaneous-electrical-acupoint-stimulation-on-symptoms-associated-with-chemotherapy-induced-peripheral-neuropathy-100508739","NCT05904340","Transcutaneous Electrical Acupoint Stimulation on Symptoms Associated with Chemotherapy Induced Peripheral Neuropathy","The Efficacy of Social Media Assisted Home-based Transcutaneous Electrical Acupoint Stimulation on Symptoms Associated with Chemotherapy Induced Peripheral Neuropathy in Patients with Breast Cancer","Inclusion Criteria:\n\n1. Primary diagnosed with breast cancer for the first time by a physician.\n2. Patients who have completed chemotherapy or postoperative adjuvant chemotherapy within 3 months, and the chemotherapy drugs used are paclitaxel, vinblastine or platinum drugs.\n3. Patients who have been evaluated by doctors as peripheral neuropathy caused by chemotherapy, and whose symptoms persist after completing chemotherapy.\n4. Peripheral sensory or peripheral motor neuropathy grade ≥ 2 in general toxicity criteria (NCI-CTCAE).\n5. Those who have clear consciousness and can communicate in Mandarin or Taiwanese.\n\nExclusion Criteria:\n\n1. Patients suffering from carcinoma in situ.\n2. Patients suffering from stage IV cancer.\n3. Patients suffering from metastatic cancer.\n4. Patients receiving peripheral neuropathy drugs (Duloxetine)\n5. Patients receiving acupoint stimulation therapy.\n6. Patients who are allergic to silicone patches.\n7. Patients with cardiac pacemakers.\n8. Patients suffering from diabetic peripheral neuropathy.\n9. Patients suffering from peripheral neuropathy of acquired immunodeficiency syndrome.\n10. Patients receiving treatment for mental illness.",{"count":318,"type":20},86,[23],"Breast cancer ranks first in Taiwan's top ten gynecological cancers. Chemotherapy is a standard treatment method for colorectal cancer and breast cancer, but while destroying cancer cells, it also destroys healthy cells, resulting in side effects. Peripheral neuropathy can lead to peripheral nerve damage and decreased activity, which affects the patient's quality of life. Currently, there is no standard and effective method for treating peripheral neuropathy caused by chemotherapy. Therefore, the purpose of this study is to investigate the effect of percutaneous electrical acupoint stimulation on improving peripheral nerve symptoms in breast cancer patients undergoing chemotherapy.",[322,323],"Breast Neoplasms","Chemotherapy-induced Peripheral Neuropathy",[325,326,327,328],"Breast Cancer","Chemotherapy-Induced Peripheral Neuropathy","Transcutaneous Electrical Nerve Stimulation","Transcutaneous Electrical Acupoint Stimulation","2024-11-04",{"date":331,"type":34},"2024-11-06",{"date":333,"type":34},"2023-07-01",{"date":259,"type":20},{"name":39,"class":40},{"id":337,"slug":338,"hasResults":11,"nctId":339,"briefTitle":340,"officialTitle":341,"acronym":4,"eligibilityCriteria":342,"healthyVolunteers":11,"sex":49,"minAge":17,"maxAge":343,"enrollmentInfo":344,"targetDuration":4,"studyType":21,"phases":346,"briefSummary":347,"conditions":348,"keywords":351,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":356,"lastUpdatePostDateStruct":357,"startDateStruct":359,"completionDateStruct":361,"leadSponsor":363,"locationsCount":41},"100564093","exploring-the-effect-of-footbaths-on-increasing-the-success-rates-in-vitro-fertilization-100564093","NCT06624683","Exploring the Effect of Footbaths on Increasing the Success Rates in Vitro Fertilization","Exploring the Effect of Footbaths on Increasing the Success Rates of in Vitro Fertilization and Its Associated Mechanism","Inclusion Criteria:\n\n* women aged 18\\~45 years\n* diagnosed with male factor infertility\n* tubal factor infertility, or unexplained infertility, and undergoing an IVF treatment.\n\nExclusion Criteria:\n\n* participants having adenomyosis, severe endometriosis\n* a history of more than two IVF treatments\n* any comorbidity or uncontrolled systemic diseases such as hypertension, diabetes, chronic heart disease or chronic renal disease that can affect the treatment process.","45 Years",{"count":345,"type":20},80,[23],"To evaluate the effectiveness of warm-water footbaths in enhancing pregnancy rates during IVF and to explore the underlying mechanisms involved.",[349,350],"Infertility","In Vitro Fertilization",[349,352,295,353,354,355],"In vitro fertilization","Sleep quality","Inflammation","Footbath","2024-10-02",{"date":358,"type":34},"2024-10-03",{"date":360,"type":20},"2024-10",{"date":362,"type":20},"2025-10",{"name":39,"class":40},{"id":365,"slug":366,"hasResults":11,"nctId":367,"briefTitle":368,"officialTitle":369,"acronym":4,"eligibilityCriteria":370,"healthyVolunteers":136,"sex":16,"minAge":81,"maxAge":371,"enrollmentInfo":372,"targetDuration":4,"studyType":21,"phases":374,"briefSummary":375,"conditions":376,"keywords":380,"overallStatus":65,"whyStopped":4,"lastUpdateSubmitDate":385,"lastUpdatePostDateStruct":386,"startDateStruct":387,"completionDateStruct":389,"leadSponsor":390,"locationsCount":41},"100563204","effectiveness-of-symptom-management-application-on-parental-care-ability-of-children-with-tourette-syndrome-100563204","NCT06613126","Effectiveness of Symptom Management Application on Parental Care Ability of Children With Tourette Syndrome","Constructing and Evaluating the Effectiveness of an Intelligent Interaction System for Symptom Management on the Care Needs and Related Factors of Children With Tourette Syndrome and Their Parents","Inclusion Criteria:\n\n1. Parents of children between 6-12 years old who are diagnosed with Tourette Syndrome by pediatricians.\n2. Parents who are the primary caregivers\n3. Parents with normal cognitive functioning who can communicate in Mandarin.\n\nExclusion Criteria:\n\n1\\. Children with Tourette Syndrome who are suffering from intellectual disability or critical diseases.","60 Years",{"count":373,"type":20},180,[23],"This study developed a Tourette Syndrome (TS) symptom management application (APP) to improve the care needs, sleep quality, anxiety, quality of life, and parenting relationship of parents of children with Tourette Syndrome.",[377,378,379],"Tourette Syndrome","Tic Disorder","Neurodevelopmental Disorder",[381,382,383,384],"symptom management","Application","parent","children with Tourette Syndrome","2024-09-30",{"date":358,"type":34},{"date":388,"type":34},"2024-09-25",{"date":72,"type":20},{"name":39,"class":40},{"id":392,"slug":393,"hasResults":11,"nctId":394,"briefTitle":395,"officialTitle":396,"acronym":4,"eligibilityCriteria":397,"healthyVolunteers":11,"sex":16,"minAge":81,"maxAge":82,"enrollmentInfo":398,"targetDuration":4,"studyType":21,"phases":399,"briefSummary":400,"conditions":401,"keywords":407,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":416,"lastUpdatePostDateStruct":417,"startDateStruct":419,"completionDateStruct":421,"leadSponsor":423,"locationsCount":4},"100533853","study-on-the-effect-of-incentive-spirometer-based-respiratory-training-on-the-long-covid-19-100533853","NCT06231225","Study on the Effect of Incentive Spirometer-based Respiratory Training on the Long COVID-19","Study on the Effect of Incentive Spirometer-based Respiratory Training on the Long COVID-19 Symptoms in Chronic Disease Patients After Recovery From COVID-19","Inclusion Criteria:\n\n1. Individuals who have contracted and recovered from COVID-19 within the past year must present proof of diagnosis, such as medical certificates or screening results. The ICD-10 diagnosis codes are: U07.1 for confirmed COVID-19 viral infection, and U09.0 for post-COVID-19 condition, unspecified. Recovery is defined as testing negative in a COVID-19 rapid test.\n2. Never diagnosed with hypertensive diseases (ICD-10 codes: I10.x or I11.x), diabetes (ICD-10 codes: E10.x or E11.x), or heart diseases (ICD-10 codes: I25.x, I50.x, I65.x, or I67.x and classified as Class I or II by the New York Heart Association functional classification).\n3. Exhibiting long-term respiratory symptoms related to COVID-19, such as post-exertional breathlessness, chest discomfort, cough, difficulty breathing, rapid breathing, etc., and meeting at least one of these criteria for inclusion.\n4. Aged between 20 - 90 years.\n5. Able to communicate in and understand Mandarin or Taiwanese, either verbally or non-verbally.\n6. Willing to participate in the study and agree to be assigned.\n\nExclusion Criteria:\n\n1. Patients with a functional status classified as level 5 or higher on the Modified Rankin Scale (MRS), indicating severe disability and bedridden status.\n2. Patients suffering from dementia, such as Alzheimer's, Parkinson's disease, etc.\n3. Patients with acute psychiatric symptoms who are unable to communicate.\n4. Individuals with a high risk of litigation.\n5. Patients suffering from Chronic Obstructive Pulmonary Disease (COPD) or any other respiratory system diseases.\n6. Patients with moderate or severe heart disease, classified as Class III or IV by the New York Heart Association functional classification.\n\n   \\-",{"count":200,"type":20},[23],"The COVID-19 pandemic has emerged as the most significant public health crisis of the 21st century. As of the end of January 2023, global confirmed cases have exceeded 670 million, with a domestic cumulative total of 10.24 million cases, including occurrences of reinfection. Beyond acute symptoms following infection, patients and society face the challenge of long-term complications associated with COVID-19. Termed 'Post COVID-19 condition' or 'Long COVID' by the World Health Organization (WHO), this encompasses symptoms appearing within three months of the initial infection. Symptoms of Long COVID reveal chronic damage inflicted by the virus on multiple organ systems, including fatigue, cognitive impairment, chest tightness, palpitations, difficulty breathing, and depression.\n\nDespite continuous efforts by healthcare professionals to find suitable treatments, no medication has been confirmed to effectively prevent or reduce post-COVID-19 sequelae. These health issues impose significant burdens and disturbances on patients' quality of life, economies, and societies.",[402,403,404,405,406],"COVID-19 Pandemic","Diabetes","Hypertension","Cardiac Disease","Long COVID",[408,409,410,411,412,413,403,414,415],"COVID-19","Post-Acute COVID-19 Syndrome","Long COVID-19","respiratory training","Hypertensive diseases","Cardiac diseases","Dyspnea","Incentive Spirometer","2024-01-26",{"date":418,"type":34},"2024-01-30",{"date":420,"type":20},"2024-07-01",{"date":422,"type":20},"2026-08-01",{"name":39,"class":40},""]