[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Nazmy Edward Seif\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":105},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,51,80],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":31,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":40,"lastUpdatePostDateStruct":41,"startDateStruct":44,"completionDateStruct":45,"leadSponsor":47,"locationsCount":50},"100643185","electric-cardiometry-guided-standard-versus-restricted-fluid-therapy-in-robotic-prostaectomy-100643185",false,"NCT07626151","Electric Cardiometry-Guided Standard Versus Restricted Fluid Therapy In Robotic Prostaectomy","Effect Of Standard Versus Restricted Fluid Therapy Guided By Electric Cardiometry On Tissue Perfuison In Robotic Prostaectomy: A Randomized Controlled Study","Inclusion Criteria:\n\n* Male patient undergoing robotic assisted prostatectomy\n* ASA I-III\n\nExclusion Criteria:\n\n* ASA score more than III\n* BMI more than 40\n* Severe renal disease (GFR between 15 and 29)\n* Previous renal surgery.\n* Decompensated cardiac disease (NYHA class 3 or 4)","MALE","40 Years","80 Years",{"count":20,"type":21},90,"ESTIMATED","INTERVENTIONAL",[24],"NA","Fluid therapy during surgery is an important factor that is related to long term mortality and morbidity and it's directly related to tissue perfusion as well. The main target in any surgery is what is the optimum fluid therapy to maintain the tissue perfusion and the precise balance between hazardous effects of hypervolemia that may cause delayed wound healing due to surgical anastomosis disruption or being hypovolemic that may cause tissue ischemia as acute kidney injury.\n\nFluid management guidance changed from static methods like central venous pressure into dynamic methods like pulse pressure variation (PPV) and stroke volume variation (SVV), which are now the most famous dynamic measures.\n\nElectrical cardiometry is a non-invasive cardiac output monitor which uses electrical cardiometry, now a commonly used device, to measure SVV which can be used to guide fluid therapy during surgeries.\n\nNow robotic assisted surgery is a common method in preforming many surgeries especially urological, since it's associated with numerous desirable outcomes including shorter post-operative stay and faster return to preoperative function.\n\nWith considerations related to severe Trendelenburg position and increased intra-abdominal pressure due to pneumo-peritoneum, robotic assisted surgeries are associated with many challenges in anesthesia especially the fluid therapy.\n\nFluid therapy in robotic surgeries is an area with growing research focus that need further exploration while there are established guidelines for fluid management in traditional surgeries, the optimal protocols for robotic surgeries are less well defined, needing more research.\n\nWe aim at this study to investigate the impact of liberal versus restricted fluid intake on the tissue perfusion reflected by serum lactate \\& creatinine clearance, while guiding therapy through electrical cardiometry, to reach optimum fluid protocol in prostatic robotic surgeries.",[27,28,29,30],"Prostate Cancer","Surgery","Fluid Overload","Lactate Blood Increase",[32,33,34,35,36,37,38],"Robotic","Prostatectomy","Sugery","Anesthesia","Fluid","Electric Cardiometry","Tissue Perfusion","RECRUITING","2026-06-05",{"date":42,"type":43},"2026-06-08","ACTUAL",{"date":40,"type":43},{"date":46,"type":21},"2026-12",{"name":48,"class":49},"Nazmy Edward Seif","OTHER",1,{"id":52,"slug":53,"hasResults":11,"nctId":54,"briefTitle":55,"officialTitle":56,"acronym":4,"eligibilityCriteria":57,"healthyVolunteers":11,"sex":58,"minAge":59,"maxAge":60,"enrollmentInfo":61,"targetDuration":4,"studyType":22,"phases":63,"briefSummary":64,"conditions":65,"keywords":69,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":79,"locationsCount":50},"100404428","low-thoracic-epidural-anesthesia-for-laparoscopic-nephrectomy-100404428","NCT04546230","Low-Thoracic Epidural Anesthesia For Laparoscopic Nephrectomy.","Low-Thoracic Epidural Anesthesia For Laparoscopic Nephrectomy In Adult Patients.","Inclusion Criteria:\n\n* ASA I - II.\n* Adult patients scheduled for laparoscopic nephrectomy.\n\nExclusion Criteria:\n\n* Patient refusal.\n* Contraindication to regional anesthesia (e.g., coagulopathy, site infection).\n* Allergy to local anesthetics.","ALL","18 Years","70 Years",{"count":62,"type":21},80,[24],"Laparoscopic nephrectomy is a surgical technique to excise a diseased kidney. It's a minimally invasive technique, so when compared to open surgery, it can mean significantly less post-operative pain, shorter hospital stay, earlier return to work and daily life activities, a more favourable cosmetic result and outcomes similar to that of open surgery.\n\nRecently, advanced laparoscopic surgery has targeted older and high risk patients for general anesthesia; in these patients, regional anesthesia offers several advantages with improved patient satisfaction. Compared with alternative anesthetic techniques, epidural anesthesia may reduce the risks of venous thromboembolism, myocardial infarction, bleeding complications, pneumonia, respiratory depression and renal failure.\n\nThe aim of this study is to compare the conventional general anesthetic technique to the regional anesthesia for laparoscopic nephrectomy, in modified lateral decubitus position using low-pressure pneumoperitoneum.",[66,67,35,68],"Laparoscopic","Nephrectomy","Epidural",[70,71,72],"Epidural Anesthesia","Low-thoracic","Laparoscopic nephrectomy","2026-01-08",{"date":75,"type":43},"2026-01-12",{"date":77,"type":43},"2020-09-19",{"date":46,"type":21},{"name":48,"class":49},{"id":81,"slug":82,"hasResults":11,"nctId":83,"briefTitle":84,"officialTitle":85,"acronym":4,"eligibilityCriteria":86,"healthyVolunteers":11,"sex":58,"minAge":59,"maxAge":87,"enrollmentInfo":88,"targetDuration":4,"studyType":22,"phases":90,"briefSummary":91,"conditions":92,"keywords":95,"overallStatus":39,"whyStopped":4,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":100,"startDateStruct":101,"completionDateStruct":103,"leadSponsor":104,"locationsCount":50},"100345533","enhancing-renal-graft-function-during-donor-anesthesia-100345533","NCT03778944","Enhancing Renal Graft Function During Donor Anesthesia","Renal Graft Functional Enhancement During Donor Anesthesia: A Comparative Study of 3 Modalities","Inclusion Criteria:\n\n* end-stage renal disease, for living-donor kidney transplantation\n\nExclusion Criteria:\n\n* severe cardiac or hepatic dysfunction\n* coagulopathy","60 Years",{"count":89,"type":21},60,[24],"Renal transplantation is now recognized as the treatment of choice for patients with end-stage renal disease. An optimum anesthetic regimen should enhance the function and perfusion of the transplanted kidney. The aim of this study is to assess \\& compare the effectiveness of 3 different modalities in this respect: Mannitol, Dopamine and adequate hydration.",[93,94,35],"Renal Failure Chronic","Transplant;Failure,Kidney",[96,97,98,99,35],"Mannitol","Dopamine","Perfusion","Renal graft donor",{"date":75,"type":43},{"date":102,"type":43},"2018-12-20",{"date":46,"type":21},{"name":48,"class":49},""]