[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Necmi Kadıoğlu Hospital\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":126},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,47,78,101],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":30,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100559485","stem-cell-applications-in-biliary-atresia-patients-100559485",false,"NCT06564740","Stem Cell Applications in Biliary Atresia Patients","Umbilical Cord Derived Mesenchymal Stem Cell (UC-MSC) Transplantation in Infants with Biliary Atresia: a Prospective Randomized Controlled Trial","Inclusion Criteria:\n\n* Infants were diagnosed with liver cirrhosis due to biliary atresia following Kasai's operation.\n* The patients two months old or older and exhibited signs of cirrhosis after the procedure, including hepatomegaly, congestive splenomegaly, elevated liver enzymes, esophageal varices (confirmed by endoscopy), and cirrhosis (confirmed by liver biopsy).\n\nExclusion Criteria:\n\n* Epilepsy\n* Neurological disorders\n* Coagulation disorders\n* Diabetes\n* Syndromic type biliary atresia\n* Allergies to anesthetic agents\n* Severe health conditions such as cancer or failure of the heart, lungs, liver, or kidneys, active infections, and severe psychiatric disorders.","ALL","2 Months","18 Years",{"count":20,"type":21},64,"ESTIMATED","INTERVENTIONAL",[24],"NA","Recently, mesenchymal stem cell (MSC) transplantation has emerged as a promising treatment for liver cirrhosis in adults. Additionally, bone marrow-derived stem cell transplantation has shown success in treating children with biliary atresia (BA). This study aims to evaluate the efficacy of Umbilical Cord-Derived Mesenchymal Stem Cell (UC-MSC) therapy in BA through a multicentric randomized controlled trial.",[27,28,29],"Biliary Atresia","Fibrosis, Liver","Stem Cell",[31,32,33],"biliary atresia","liver fibrosis","stem cell","RECRUITING","2024-09-03",{"date":37,"type":38},"2024-09-19","ACTUAL",{"date":40,"type":38},"2024-06-01",{"date":42,"type":21},"2026-06-01",{"name":44,"class":45},"Necmi Kadıoğlu Hospital","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":52,"acronym":4,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":54,"minAge":55,"maxAge":56,"enrollmentInfo":57,"targetDuration":4,"studyType":22,"phases":59,"briefSummary":60,"conditions":61,"keywords":66,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":77},"100548135","caudal-anesthesia-versus-local-anesthesia-in-hypospadias-100548135","NCT06417060","Caudal Anesthesia Versus Local Anesthesia in Hypospadias","THE IMPACT OF CAUDAL BLOCK ANESTHESIA ON POSTOPERATIVE COMPLICATIONS IN DISTAL HYPOSPADIAS SURGERY: A MULTI-CENTER RANDOMIZED CONTROLLED TRIAL","Inclusion Criteria:\n\n* Aged between 6 and 48 months\n* Distal hypospadias\n* Acceptance of participation\n\nExclusion Criteria:\n\n* Midpenil hypospadias\n* Proximal hypospadias\n* Prior surgery\n* Comorbidity (diabetes, hypertention, cardiac pathology)","MALE","6 Months","48 Months",{"count":58,"type":21},200,[24],"Hypospadias is among the most common congenital genital malformations in boys and is typically treated through surgical intervention. During pediatric urological surgery, caudal anesthesia, also known as a caudal block, is frequently employed as a regional anesthetic technique. It has proven to be a safe and effective anesthetic approach in children, with a low rate of anesthesia-related complications. However, despite the low incidence of complications directly associated with the caudal block, there is limited and inconclusive evidence regarding its impact on surgical complications. Therefore, this randomized controlled superiority trial aims to evaluate whether the use of caudal anesthesia, compared to the dorsal penile block, is associated with an increased incidence of urethrocutaneous fistulas and glans dehiscence following hypospadias repair.",[62,63,64,65],"Hypospadias","Hypospadias, Coronal","Caudal Anesthesia","Children",[62,67,68],"Caudal anesthesia","Urethrocutanous fistula","2024-08-19",{"date":71,"type":38},"2024-08-20",{"date":73,"type":38},"2023-05-25",{"date":75,"type":21},"2024-08-30",{"name":44,"class":45},3,{"id":79,"slug":80,"hasResults":11,"nctId":81,"briefTitle":82,"officialTitle":83,"acronym":4,"eligibilityCriteria":84,"healthyVolunteers":11,"sex":16,"minAge":85,"maxAge":18,"enrollmentInfo":86,"targetDuration":4,"studyType":22,"phases":88,"briefSummary":89,"conditions":90,"keywords":92,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":95,"startDateStruct":96,"completionDateStruct":98,"leadSponsor":100,"locationsCount":46},"100541038","the-efficacy-of-combining-platelet-rich-plasma-with-crystallized-phenol-in-pilonidal-sinus-disease-100541038","NCT06324656","The Efficacy of Combining Platelet-rich Plasma With Crystallized Phenol in Pilonidal Sinus Disease","The Efficacy of Combining Platelet-rich Plasma With Crystallized Phenol in Pilonidal Sinus Disease Treatment in Children: A Double-blind Single-center Randomized Controlled Trial","Inclusion Criteria:\n\nThe study will be included patients with pilonidal sinus disease aged between 0 to 18 years.\n\nExclusion Criteria:\n\nPatients who had undergone prior pilonidal sinus disease surgery or had anomalies in the sacrococcygeal region will be excluded from the study. Additionally, patients who will decline to participate in the study or will be failed to attend post-procedural outpatient follow-ups will also be excluded.","1 Day",{"count":87,"type":21},100,[24],"The use of local liquid phenol for pilonidal sinus disease was first introduced by Maurica and Greenwood in 1964. Phenol, also known as carbolic acid, has been proven to be an effective sclerosing agent for treating pilonidal sinus diseas. Its antiseptic and anesthetic qualities make it suitable for application in awake patients under local anesthesia. The treatment of pilonidal sinus diseas in children with crystallized phenol was first published by Ateş et al in 2018. However, the treatment involving only crystallized phenol can require numerous sessions, potentially extending the duration of the treatment. IIn this study, the investigators, investigated whether the application of platelet-rich plasma following crystallized phenol treatment could accelerate the healing process and reach better outcomes. This study evaluates the efficacy of PRP as a treatment modality for pilonidal sinus disease in pediatric patients.",[91],"Pilonidal Sinus",[93,65,94],"pilonidal sinus","platelet rich plasma",{"date":71,"type":38},{"date":97,"type":38},"2023-11-21",{"date":99,"type":21},"2024-09-30",{"name":44,"class":45},{"id":102,"slug":103,"hasResults":11,"nctId":104,"briefTitle":105,"officialTitle":106,"acronym":4,"eligibilityCriteria":107,"healthyVolunteers":11,"sex":16,"minAge":108,"maxAge":18,"enrollmentInfo":109,"targetDuration":4,"studyType":22,"phases":110,"briefSummary":111,"conditions":112,"keywords":115,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":121,"startDateStruct":122,"completionDateStruct":124,"leadSponsor":125,"locationsCount":46},"100529718","transumbilical-laparoscopic-appendectomy-100529718","NCT06177418","Transumbilical Laparoscopic Appendectomy","Glove Finger Method to Prevent Wound Infection in Children Undergoing Transumbilical Laparoscopic Appendectomy","Inclusion Criteria:\n\npatients undergo appendectomy between 5 and 18 years.\n\nExclusion Criteria:\n\nComorbidity previous surgery","5 Years",{"count":87,"type":21},[24],"Transumbilical laparoscopic appendectomy (TULA) is increasingly favored in the treatment of appendicitis within the realm of minimally invasive surgical approaches. This procedure offers advantages such as superior cosmetic outcomes and reduced postoperative pain. However, like all surgical interventions, it carries the inherent risk of surgical site infections (SSI), which pose significant challenges to patient health and healthcare systems by escalating treatment costs, prolonging recovery, and increasing morbidity rates. This study aims to evaluate the efficacy of the \"glove finger method\" in mitigating SSI risk in TULA.\n\nThe rationale for this study is predicated on the hypothesis that the glove finger method could serve as a simple and cost-effective measure offering potential protection against SSIs. When compared to traditional methods, this technique may not only reduce surgical duration but also diminish the risk of SSIs, thereby potentially decreasing hospital stay durations. Furthermore, enhancing the understanding of factors contributing to the development of SSIs and developing effective strategies for their prevention can elevate patient care quality and alleviate the burden on healthcare systems.",[113,114],"Appendicitis","Surgical Site Infection",[116,117,118,119,120],"laparoscopic appendectomy","transumbilical laparoscopic appendectomy","appendicitis","children","surgical site infection",{"date":71,"type":38},{"date":123,"type":38},"2023-12-25",{"date":99,"type":21},{"name":44,"class":45},""]