[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Nest Genomics\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":46},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":5},"100566383","closing-the-gaps-guideline-adherence-prevention-and-surveillance-in-hereditary-cancer-100566383",false,"NCT06654466","Closing the GAPS: Guideline Adherence, Prevention and Surveillance in Hereditary Cancer","Enhancing Information Management for Young Adults After Genetic Cancer Risk Testing","Inclusion Criteria:\n\n* Ages 18-49 years, inclusive\n* previous cancer genetic testing with a finding of a pathogenic or likely pathogenic variant resulting in an increased risk of cancer warranting clinical management.\n* English-speaking and -reading\n* Receiving care at Dana Farber Cancer Institute\n* Not in active cancer therapy at the time of approach\n\nExclusion Criteria:\n\n* Age \\\u003C18 or \\>49 years\n* Has not had genetic testing for hereditary cancer syndromes or has been tested but no pathogenic or likely pathogenic variant was identified.\n* Non-English speaking and reading\n* Not receiving care at Dana Farber Cancer Institute\n* Active cancer with therapy in progress","ALL","18 Years","49 Years",{"count":20,"type":21},100,"ESTIMATED","INTERVENTIONAL",[24],"NA","The goal of this clinical trial is to see if a software platform can improve cancer screening in young adults with genetic risk for cancer.\n\nThe trial will also help improve the software platform (Nest). The main questions it aims to answer are:\n\n* Do Nest users know more about their cancer risks and recommended care than non-users?\n* Do Nest users have less psychological distress than non-users?\n* Do Nest users share cancer risks with family and other doctors more than non-users?\n* Are Nest users more likely than non-users to have up-to-date care plans?\n\nResearchers will compare Nest users to non-users to see if the Nest users are more likely to do recommended cancer screening.\n\nParticipants will:\n\n* Have a genetic counseling or follow up visit\n* Take a post-visit survey\n* Intervention arm only: use the Nest Patient Navigator\n* Complete screening and follow-up care recommended by doctors",[27,28],"Hereditary Cancer Syndromes","Clinical Decision Support",[27,30,31,32,28,33],"Cancer Surveillance","Cancer Prevention","Guideline Adherence","Adolescent and Young Adult Cancer","RECRUITING","2026-02-23",{"date":37,"type":38},"2026-02-25","ACTUAL",{"date":40,"type":38},"2026-02-10",{"date":42,"type":21},"2027-09",{"name":44,"class":45},"Nest Genomics","INDUSTRY",""]