[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Nicholas Skertich\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":39},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":4,"eligibilityCriteria":14,"healthyVolunteers":11,"sex":15,"minAge":16,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":5},"100572515","early-phase-1-randomized-control-trial-of-sleeve-gastrectomy-with-tirzepatide-in-maximizing-weight-loss-100572515",false,"NCT06734273","Randomized Control Trial of Sleeve Gastrectomy With Tirzepatide in Maximizing Weight Loss","Inclusion Criteria:\n\n* Adult 18 to 65 years of age\n* Body Mass Index \\>35 with comorbidity of Type 2 Diabetes and\u002For Hypertension and\u002For Hyperlipidemia and\u002For Obstructive Sleep Apnea OR Body Mass Index \\>40 with or without comorbidity\n* Undergoing primary sleeve gastrectomy\n\nExclusion Criteria:\n\n* Prior metabolic and bariatric surgery\n* Prior use of GLP-1 agonist\n* Prior history of pancreatitis\n* Personal\u002Ffamily history of medullary thyroid cancer or MEN type 2\n* Secondary cause of obesity\n* Any eating disorder\n* Pregnancy\u002Flactation\n* History of acute coronary syndrome or myocardial infarction\n* History of stroke\n* Hepatic dysfunction: AST\u002FALT \\>3 ULN\n* Renal dysfunction eGFR\\\u003C45ml\u002Fmin\u002F1.73m2\n* Active malignancy\n* History of diabetic retinopathy\n* History of gastroparesis","ALL","18 Years","65 Years",{"count":19,"type":20},42,"ESTIMATED","INTERVENTIONAL",[23],"EARLY_PHASE1","This study examines whether adding tirzepatide-a medication that helps with weight loss-after sleeve gastrectomy surgery can help people lose more weight after the surgery; better improve conditions like Type 2 diabetes, high blood pressure, high cholesterol, and sleep apnea after surgery and; whether this causes more complications or side effects compared to surgery alone.",[26],"Obesity and Obesity-related Medical Conditions","RECRUITING","2026-05-05",{"date":30,"type":31},"2026-05-08","ACTUAL",{"date":33,"type":31},"2025-03-10",{"date":35,"type":20},"2028-09",{"name":37,"class":38},"Nicholas Skertich","OTHER",""]