[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Nicklaus Children's Hospital f\u002Fk\u002Fa Miami Children's Hospital\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":72},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,43],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100631628","prospective-evaluation-of-cardiac-point-of-care-ultrasound-pocus-performed-by-pem-fellows-and-artificial-intelligence-on-children-with-pre-existing-cardiac-conditions-100631628",false,"NCT07503158","Prospective Evaluation of Cardiac Point-of-Care Ultrasound (POCUS) Performed by PEM Fellows and Artificial Intelligence on Children With Pre-existing Cardiac Conditions.","Prospective Evaluation of Cardiac Point-of-Care Ultrasound (POCUS) Performed by PEM Fellows and Artificial Intelligence Interpretation Compared With a Complete Echocardiography in Children With Preexisting Cardiac Disease","POCUS-AI PEM","Inclusion Criteria:\n\n* Children aged 0-21 years\n* Preexisting cardiac disease\n* Participants are either evaluated in the ED or in the cardiology setting.\n\nExclusion Criteria:\n\n* Participant's clinical condition requires immediate life-saving interventions\n* New diagnosis of cardiac condition\n* Preexisting cardiac abnormality documented prior to the index encounter.","ALL","1 Month","21 Years",{"count":21,"type":22},200,"ESTIMATED","OBSERVATIONAL","The goal of this study is to prospectively assess the diagnostic agreement of PEM fellow-performed cardiac POCUS and of AI-assisted interpretation using the Exo Iris probe, as compared to a complete echocardiography for detecting left ventricular (LV) systolic dysfunction and pericardial effusion in children with preexisting cardiac disease.",[26],"Cardiac Anomalies",[28,29],"POCUS AI","Children","NOT_YET_RECRUITING","2026-04-02",{"date":33,"type":34},"2026-04-08","ACTUAL",{"date":36,"type":22},"2026-03-30",{"date":38,"type":22},"2028-03-30",{"name":40,"class":41},"Nicklaus Children's Hospital f\u002Fk\u002Fa Miami Children's Hospital","OTHER",1,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":4,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":17,"minAge":4,"maxAge":19,"enrollmentInfo":50,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":52,"conditions":53,"keywords":56,"overallStatus":63,"whyStopped":4,"lastUpdateSubmitDate":64,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":69,"leadSponsor":71,"locationsCount":42},"100320986","diagnostic-odyssey-whole-genome-sequencing-wgs-100320986","NCT03458962","Diagnostic Odyssey: Whole Genome Sequencing (WGS)","Ending the Diagnostic Odyssey: Whole Genome Sequencing (WGS) to Identify Genetic Determinants of Previously Undiagnosed Disease in Children","Inclusion Criteria:\n\n* Symptomatic male or female children ages 0-21 who have un unknown medical condition thought to have an underlying genetic cause after parental consent has been obtained.\n* Willingness of referring provider or other qualified medical staff member to participate in this study by facilitating collection of biologic specimens and clinical information.\n* Patient whose medical condition can be reasonably attributed to a possible genetic etiology.\n* Patient have had at least one diagnostic test without a definite diagnosis.\n\nExclusion Criteria:\n\n* Unwillingness to consent to research.\n* Affected adults (\\>21 years of age), unless they are a biological relative of the affected child.\n* Any patient whose medical condition cannot be reasonably attributed to a possible genetic etiology or there is a prior diagnosis that explains the child's clinical presentation.",{"count":51,"type":22},1000,"The goal of this collaborative research is to study human genomes in children with suspected congenital disease, multiple-congenital anomalies and\u002For multi-organ disease of unknown etiology by understanding the potential value of Whole Genome Sequencing (WGS) in establishing genetic diagnosis. The study will examine diagnosis rates, changes in clinical care as a result of a genetic diagnosis, health economics including potential cost-effectiveness of WGS and patient and provider experience with genomic medicine.",[54,55],"Genetic Disease","Genetic Syndrome",[57,58,59,60,61,62],"Nicklaus Children's","Pediatric","Genomic","Precision Medicine","Biorepository","Rady Children's","RECRUITING","2024-11-06",{"date":66,"type":34},"2024-11-07",{"date":68,"type":34},"2018-02-20",{"date":70,"type":22},"2070-03",{"name":40,"class":41},""]