[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Nigde Omer Halisdemir University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":695},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,25,0,[8,41,76,103,132,163,188,216,245,272,306,333,356,387,416,444,466,491,515,540,562,588,617,644,669],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":23,"studyType":24,"phases":4,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100642564","evaluation-of-gingival-crevicular-fluid-cytokine-profiles-in-children-and-young-adults-with-gingivitis-100642564",false,"NCT07607639","Evaluation of Gingival Crevicular Fluid Cytokine Profiles in Children and Young Adults With Gingivitis","Comparison of Gingival Crevicular Fluid Biomarkers Between Childhood Gingivitis and Adolescent Gingivitis","Inclusion Criteria:\n\n1. Individuals aged 8-12 years (child group) or 15-24 years (young adult group)\n2. Clinical diagnosis of gingivitis\n3. Presence of fully erupted tooth #31 with closed apex\n4. Systemically healthy individuals\n5. No history of periodontal treatment in the last 3 months\n6. No antibiotic or anti-inflammatory drug use in the last 3 months\n7. Good cooperation and willingness to participate\n8. Written informed consent from participants or legal guardians (for minors)\n\nExclusion Criteria:\n\n1. Age 13-14 years (transitional pubertal period)\n2. Presence of periodontitis or other periodontal diseases\n3. Systemic, genetic, or immunological diseases\n4. Acute oral infections or conditions requiring emergency treatment\n5. Orthodontic appliances in the sampling region\n6. Smokers\n7. Pregnant or lactating individuals\n8. Individuals with cognitive, psychological, or physical disabilities affecting cooperation\n9. Inadequate eruption or incomplete root development of tooth #31\n10. Refusal to participate or withdrawal of consent",true,"ALL","8 Years","24 Years",{"count":21,"type":22},80,"ESTIMATED","1 Day","OBSERVATIONAL","This prospective observational case-control study aims to compare gingival crevicular fluid (GCF) biomarker profiles between children and young adults diagnosed with gingivitis. A total of approximately 80 systemically healthy participants will be recruited and divided into two groups: children aged 8-12 years and young adults aged 15-24 years. Individuals aged 13-14 years will be excluded as they represent a transitional pubertal period characterized by significant hormonal fluctuations that may influence inflammatory responses and confound biomarker levels.\n\nClinical periodontal parameters including gingival index, plaque index, bleeding on probing, and probing depth will be recorded. In addition, GCF samples will be collected from a standardized tooth and analyzed for levels of IL-1β, TNF-α, IL-10, and MMP-8 using enzyme-linked immunosorbent assay (ELISA).\n\nThe primary objective of the study is to evaluate and compare inflammatory and anti-inflammatory cytokine profiles between the two age groups. The findings may contribute to understanding age-related differences in gingival inflammatory responses and the potential role of hormonal transition in periodontal disease expression during childhood and early adulthood.",[27],"Gingivitis","RECRUITING","2026-06-08",{"date":31,"type":32},"2026-06-10","ACTUAL",{"date":34,"type":32},"2026-05-22",{"date":36,"type":22},"2027-11",{"name":38,"class":39},"Nigde Omer Halisdemir University","OTHER",1,{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":4,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":48,"minAge":49,"maxAge":50,"enrollmentInfo":51,"targetDuration":4,"studyType":53,"phases":54,"briefSummary":56,"conditions":57,"keywords":60,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":68,"lastUpdatePostDateStruct":69,"startDateStruct":71,"completionDateStruct":73,"leadSponsor":75,"locationsCount":40},"100639182","mindfulness-psychoeducation-based-on-transtheoretical-model-for-fear-of-childbirth-100639182","NCT07624253","Mindfulness Psychoeducation Based on Transtheoretical Model for Fear of Childbirth","The Effect of Mindfulness-Based Psychoeducation Provided According to the Transtheoretical Model on Fear of Childbirth, Self-Perception, and Spiritual Well-Being in Pregnant Women With Fear of Childbirth","Inclusion Criteria:\n\n* Willing to participate in the study,\n* Aged between 18-40 years,\n* Primigravida (first pregnancy),\n* Not having received any childbirth preparation class,\n* Scoring 38 or above on the Wijma Delivery Expectancy\u002FExperience Questionnaire,\n* Between 20 and 34 weeks of gestation,\n* Having a healthy pregnancy,\n* Having a singleton pregnancy,\n* Carrying a live fetus,\n* Not in active labor,\n* Able to speak Turkish and without any language, comprehension, or communication problems to understand and answer the questions.\n\nExclusion Criteria:\n\n* Those who do not agree to participate in the study,\n* Pregnant women under 18 years of age and over 41 years of age,\n* Diagnosed with high-risk pregnancy,\n* Illiterate,\n* Having a contagious disease,\n* Having a current or past psychiatric disorder requiring treatment,\n* Having mobility, hearing, or psychological disabilities,\n* With a gestational age below 20 weeks or above 32 weeks,\n* Those who have entered active labor.\n\nWithdrawal \u002F Exclusion Criteria\n\n* Participants who withdraw consent and wish to leave the study during the study period,\n* Participants who are unable to adapt to the intervention process,\n* Participants experiencing communication or internet connectivity problems,\n* Participants who develop complications during the intervention (e.g., onset of labor, decreased fetal movements, etc.) requiring hospitalization will be excluded from the study.","FEMALE","18 Years","40 Years",{"count":52,"type":22},72,"INTERVENTIONAL",[55],"NA","Childbirth is a significant life event with important physical and psychological effects on pregnant women. Due to uncertainty during pregnancy, many women experience fear of childbirth. Fear of childbirth is a common condition that may negatively affect maternal well-being. Therefore, various psychosocial interventions have been developed to reduce this condition. Mindfulness-based approaches and psychoeducation programs are considered effective methods for reducing stress, anxiety, and fear by promoting non-judgmental awareness of the present moment.\n\nThis study is designed as a randomized controlled experimental trial. The study population will consist of pregnant women attending the Obstetrics and Gynecology Outpatient Clinic of Niğde Ömer Halisdemir Training and Research Hospital who meet the inclusion criteria. The sample size was calculated using G\\*Power 3.1.9.7 software. Based on an effect size of f = 0.38, 80% statistical power, and a 5% significance level, a minimum of 30 participants was required. Considering a 20% potential dropout rate, a total of 72 pregnant women (36 intervention and 36 control) will be included in the study.\n\nThe inclusion criteria are being between 18 and 40 years of age, having a first pregnancy, being between 20 and 34 weeks of gestation, having a singleton and healthy pregnancy, being able to communicate in Turkish, and scoring 38 or higher on the Wijma Delivery Expectancy\u002FExperience Questionnaire (Version A). Women with high-risk pregnancies, a history of psychiatric disorders, illiteracy, communication problems, or unwillingness to participate will be excluded. Withdrawal during the study, development of pregnancy complications, or inability to continue the intervention will be considered exclusion criteria.\n\nData will be collected using a Sociodemographic Information Form, the Wijma Delivery Expectancy\u002FExperience Questionnaire (W-DEQ A), the Self-Perception Scale for Pregnant Women, and the Spiritual Well-Being Scale. The W-DEQ A measures fear of childbirth, the Self-Perception Scale assesses maternal and body perception during pregnancy, and the Spiritual Well-Being Scale evaluates the level of spiritual well-being.\n\nAt the beginning of the study, eligible participants will be informed about the research and written informed consent will be obtained. Data collection forms will first be administered face-to-face. Pregnant women scoring 38 or above on the W-DEQ A will then be randomly assigned to intervention and control groups using a computer-based randomization method (randomizer.org).\n\nThe intervention group will receive a mindfulness-based psychoeducation program adapted according to the Transtheoretical Model. The intervention will be delivered in group sessions of 6-10 participants, twice a week for 4 weeks, with each session lasting approximately 45-60 minutes. The program includes psychoeducation about pregnancy and childbirth, mindfulness exercises, emotional awareness activities, and coping strategies for fear of childbirth.\n\nThe control group will receive routine obstetric care only. Post-intervention assessments will be conducted in both groups using the same measurement tools.\n\nData analysis will be performed using SPSS version 25.0. Descriptive statistics will be calculated, and depending on data distribution, independent samples t-test, paired samples t-test, ANOVA, Mann-Whitney U test, Kruskal-Wallis test, and chi-square test will be used. The level of statistical significance will be set at p \\\u003C 0.05.\n\nThe aim of this study is to evaluate the effect of a mindfulness-based psychoeducation intervention based on the Transtheoretical Model on fear of childbirth, self-perception, and spiritual well-being in pregnant women experiencing fear of childbirth.",[58,59],"Fear of Childbirth","Pregnancy",[61,62,63,64,65,66],"fear of childbirth","pregnancy","mindfulness","psychoeducation","self-perception","spiritual well-being","NOT_YET_RECRUITING","2026-05-31",{"date":70,"type":32},"2026-06-03",{"date":72,"type":22},"2026-07-15",{"date":74,"type":22},"2028-07-15",{"name":38,"class":39},{"id":77,"slug":78,"hasResults":11,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":4,"eligibilityCriteria":82,"healthyVolunteers":16,"sex":17,"minAge":83,"maxAge":84,"enrollmentInfo":85,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":87,"conditions":88,"keywords":91,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":99,"completionDateStruct":100,"leadSponsor":102,"locationsCount":40},"100638128","fathers-involvement-in-infant-care-and-infants-development-100638128","NCT07627126","Fathers' Involvement in Infant Care and Infants' Development","Fathers' Involvement in Infant Care and Infants' Sensory Processing","Inclusion Criteria:\n\n* Term infants (37-40 weeks),\n* Infants aged 4-6 months\n\nExclusion Criteria:\n\n* Preterm infants,\n* Infants with congenital infections or proven genetic changes,\n* Infants and mothers diagnosed with metabolic, neurological, and genetic diseases,\n* Children whose parents did not volunteer to study","4 Months","6 Months",{"count":86,"type":22},75,"In the early stages of life, newborns are dependent on caregivers to meet their basic needs for survival, feeding, and care. Generally, mothers assume primary responsibility for meeting their infants' basic needs and providing care, while fathers take on a supporting role. Both mothers and fathers actively contribute to the baby's healthy emotional development. This study, planned with fathers of 4-6 month old infants, addresses the lack of quantitative evidence regarding the relationship between fathers' involvement in infant care and infants' sensory processing.",[89,90],"Infant Behavior","Father - Child Relations",[92,93,94,95],"Infant","Sensory Processing","Father","Infant Care","2026-05-30",{"date":98,"type":32},"2026-06-04",{"date":96,"type":32},{"date":101,"type":22},"2027-03-15",{"name":38,"class":39},{"id":104,"slug":105,"hasResults":11,"nctId":106,"briefTitle":107,"officialTitle":108,"acronym":4,"eligibilityCriteria":109,"healthyVolunteers":16,"sex":48,"minAge":49,"maxAge":110,"enrollmentInfo":111,"targetDuration":4,"studyType":53,"phases":113,"briefSummary":114,"conditions":115,"keywords":119,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":125,"startDateStruct":127,"completionDateStruct":129,"leadSponsor":131,"locationsCount":40},"100624539","postpartum-acupressure-education-and-breastfeeding-outcomes-100624539","NCT07410949","Postpartum Acupressure Education and Breastfeeding Outcomes","Effect of Postpartum Acupressure Education on Breastfeeding Outcomes: A 12-Month Randomized Controlled Trial","Inclusion Criteria:\n\n* Age 18 to 45 years\n* Term singleton birth (≥37 weeks of gestation)\n* ≤48 hours postpartum at the time of enrollment\n* Intention to breastfeed\n* Ability to communicate in Turkish\n* Access to a smartphone for educational materials and follow-up reminders\n* Willingness to provide written informed consent\n\nExclusion Criteria:\n\n* Contraindications to breastfeeding (e.g., infant galactosemia)\n* Severe neonatal condition preventing breastfeeding\n* Severe maternal medical or psychiatric condition interfering with breastfeeding\n* Current opioid, alcohol, or substance dependence\n* Multiple gestation pregnancy\n* Severe breast injury or condition within the first 72 hours postpartum preventing breastfeeding","45 Years",{"count":112,"type":22},360,[55],"This randomized controlled trial evaluates whether acupressure education provided to mothers within the first 48 hours postpartum improves exclusive breastfeeding rates at 6 months compared with standard postpartum care alone. Mothers in the intervention group will receive structured education on self-administered acupressure at selected points and will be encouraged to continue home-based practice, while the control group will receive standard breastfeeding support. Participants will be followed for 12 months to assess breastfeeding continuation, breastfeeding self-efficacy, breastfeeding quality, and breastfeeding-related outcomes.",[116,117,118],"Breastfeeding","Lactation","Postpartum Period",[120,121,122,123,124],"Acupressure","Postpartum","Exclusive breastfeeding","Breastfeeding continuation","Breastfeeding self-efficacy",{"date":126,"type":32},"2026-06-02",{"date":128,"type":32},"2026-04-25",{"date":130,"type":22},"2027-02-15",{"name":38,"class":39},{"id":133,"slug":134,"hasResults":11,"nctId":135,"briefTitle":136,"officialTitle":137,"acronym":4,"eligibilityCriteria":138,"healthyVolunteers":16,"sex":48,"minAge":49,"maxAge":139,"enrollmentInfo":140,"targetDuration":4,"studyType":53,"phases":142,"briefSummary":143,"conditions":144,"keywords":149,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":157,"startDateStruct":158,"completionDateStruct":160,"leadSponsor":162,"locationsCount":40},"100624538","self-acupressure-and-social-jet-lag-in-female-health-sciences-students-100624538","NCT07410936","Self-Acupressure and Social Jet Lag in Female Health Sciences Students","Effects of Self-Acupressure on Social Jet Lag, Sleep Patterns, and Sleep Quality in Female Health Sciences Students: A Sham-Controlled Randomized Trial","Inclusion Criteria:\n\n* Female undergraduate students enrolled in midwifery or medical programs\n* Age 18 to 25 years\n* Regular academic schedule (work\u002Fschool days and free days identifiable)\n* Willingness to participate and provide written informed consent\n* Ability to comply with daily self-acupressure practice for 12 weeks\n* Ability to complete sleep questionnaires and sleep diary\n\nExclusion Criteria:\n\n* Current diagnosis of a sleep disorder requiring medical treatment (e.g., obstructive sleep apnea, narcolepsy)\n* Use of medications known to significantly affect sleep or circadian rhythms (e.g., hypnotics, stimulants)\n* Shift work or night work during the study period\n* Transmeridian travel (≥2 time zones) within the past 4 weeks or planned during the study period\n* Chronic medical or psychiatric condition that may significantly affect sleep\n* Current pregnancy","25 Years",{"count":141,"type":22},120,[55],"This randomized, sham-controlled trial aims to evaluate the effects of self-administered acupressure on social jet lag, sleep patterns, and sleep quality in female health sciences students. Participants will be randomly assigned to either a self-acupressure intervention group or a sham self-acupressure control group. The intervention will be performed daily for 12 weeks. Outcomes will be assessed at baseline and at the end of the intervention period, with the primary outcome being the change in social jet lag. Secondary outcomes include changes in sleep quality, daytime sleepiness, and participant blinding assessment.",[145,146,147,148],"Social Jet Lag","Sleep Disturbance","Sleep Quality","Circadian Rhythm Disruption",[150,151,152,153,154,155,156],"Self-acupressure","Social jet lag","Sleep quality","Sleep patterns","Circadian rhythm","University students","Sham-controlled trial",{"date":126,"type":32},{"date":159,"type":32},"2026-04-24",{"date":161,"type":22},"2026-08-15",{"name":38,"class":39},{"id":164,"slug":165,"hasResults":11,"nctId":166,"briefTitle":167,"officialTitle":167,"acronym":4,"eligibilityCriteria":168,"healthyVolunteers":16,"sex":17,"minAge":49,"maxAge":169,"enrollmentInfo":170,"targetDuration":4,"studyType":53,"phases":172,"briefSummary":173,"conditions":174,"keywords":4,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":180,"lastUpdatePostDateStruct":181,"startDateStruct":183,"completionDateStruct":185,"leadSponsor":187,"locationsCount":4},"100638265","the-effect-of-aromatherapy-massage-based-sensory-stmulaton-program-on-cogntve-and-sensory-functon-n-intensve-care-patents-100638265","NCT07593430","The Effect of Aromatherapy Massage-Based Sensory Stımulatıon Program on Cognıtıve and Sensory Functıon ın Intensıve Care Patıents","Inclusion Criteria:\n\n* Patients diagnosed with acute brain injury,\n* Glasgow Coma Score (GCS) between 6 and 12,\n* Intubated or monitored on oxygen,\n* 18 years of age or older,\n* Between 24 and 48 hours after hemodynamic vital signs stabilized and without a history of delirium,\n* Patients without a history of diseases that increase the risk of odor sensitivity, such as epilepsy or asthma,\n\nExclusion Criteria:\n\n* Glasgow Coma Score (GCS) below 6,\n* Hemodynamic instability,\n* Continuously using neuromuscular blocking agents during the study,\n* Changes in treatment schedule during the study,\n* History of diseases that increase the risk of odor sensitivity, such as epilepsy or asthma,","90 Years",{"count":171,"type":22},60,[55],"Background: Sensory stimulation is a treatment that uses auditory, visual, tactile, gustatory, and olfactory stimuli, as well as balance and position modes, with intensity and frequency adjusted to the patient's individual thresholds to increase the frequency of arousal, awareness, and pronounced behavioral responses. Studies have shown that sensory stimulation, especially when applied from the beginning of the patient's hospitalization, can shorten the average length of stay and reduce patient anxiety. Among the TIT methods applied by nurses, touch, music therapy, and aromatherapy are included as applications that can be applied to the sensory input problems of intensive care patients and can positively affect their sensory perceptions.Objective: This study is planned to be conducted as a randomized controlled single-blind study to determine the effect of a sensory stimulation program performed with aromatherapy massage applied twice daily for 7 days with a mixture of orange, patchouli, and rosemary oil (7 drops of sweet orange oil, 5 drops of patchouli oil, and 3 drops of rosemary oil in 50 ml of jojoba oil) on the cognitive sensory perception level of patients monitored on mechanical ventilation or oxygen in the ICU.Method: In the study, all patients hospitalized in the tertiary care ICU of the University's Training and Research Hospital will constitute the population. Randomized sampling method will be used in the study. Sample size; G\\*power 3.5.1. In the power analysis performed with the software package, it is planned that each group will consist of at least 20 people to determine an effect size of 1% with an alpha risk of 0.05 and a power of 0.80 in line with the literature. The data collection tools to be used are: Patient Identification Form, Patient Monitoring Form, Medication Monitoring Form, Glasgow Coma Scale, Rancho Los Amigos Cognitive Function Scale. In Intervention Group 1, massage will be performed by the lead researcher ICU nurse, and the sensory stimulation program will be performed by a trained family member. In Intervention Group 2, massage will be performed by the lead researcher ICU nurse, and the sensory stimulation program will be performed by a nurse. Routine care will be provided to the control group. Since the groups are compared, the independent samples t-test and the Shapiro-Wilk test, which are parametric tests, will be used for evaluation.",[175,176,177,178,179],"Cognitive Sensory Perception Level","in Unconscious Patients","Lung Disaases","Cerebro Vascular Disease","Trauma Patients","2026-05-13",{"date":182,"type":32},"2026-05-18",{"date":184,"type":22},"2026-06-01",{"date":186,"type":22},"2027-06",{"name":38,"class":39},{"id":189,"slug":190,"hasResults":11,"nctId":191,"briefTitle":192,"officialTitle":193,"acronym":4,"eligibilityCriteria":194,"healthyVolunteers":16,"sex":17,"minAge":195,"maxAge":196,"enrollmentInfo":197,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":198,"conditions":199,"keywords":201,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":208,"lastUpdatePostDateStruct":209,"startDateStruct":211,"completionDateStruct":213,"leadSponsor":215,"locationsCount":40},"100633364","the-relationship-between-finger-ratio-and-development-in-infants-100633364","NCT07525726","The Relationship Between Finger Ratio and Development in Infants","The Relationship Between Digit Ratio and Motor Development and Sensory Processing in Infants","Inclusion Criteria:\n\n* Term infants (37-40 weeks),\n* Infants aged 12-18 months\n\nExclusion Criteria:\n\n* Preterm infants,\n* Infants with congenital infections or proven genetic changes,\n* Infants and mothers diagnosed with metabolic, neurological, and genetic diseases,\n* Maternal diabetes,\n* Intrauterine growth retardation,\n* Infants with a history of hand-related surgery,\n* Children whose parents did not volunteer to study","12 Months","18 Months",{"count":21,"type":22},"One of the most prominent indicators of prenatal androgen exposure is considered to be the ratio of second and fourth finger lengths (2D:4D). The 2D:4D finger ratio refers to the ratio of the length of the second finger (2D; index finger) and the fourth finger (4D; ring finger). Evidence suggests that 2D:4D is developmentally stable and stabilizes from the second trimester of pregnancy. It has been reported that the 2D:4D ratio correlates positively with estrogen and negatively with testosterone. In both sexes, prenatal testosterone levels are inversely related by a 2D:4D ratio, which does not change with age. Androgens can have direct trophic effects on target cells or indirectly affect neuronal growth through neurotrophic mediators released locally by steroid-sensitive neuronal or glial cells. Prenatal testosterone can have long-term organizational effects on the structure and function of various body systems (e.g., cardiovascular and musculoskeletal systems) that are important for physical activity and exercise.",[200],"Infant Developmental Assessment",[202,203,204,205,206,207],"motor development","sensory processing","2D:4D ratio","digit ratio","infant","Prenatal androgen","2026-05-04",{"date":210,"type":32},"2026-05-08",{"date":212,"type":32},"2026-04-06",{"date":214,"type":22},"2027-04-01",{"name":38,"class":39},{"id":217,"slug":218,"hasResults":11,"nctId":219,"briefTitle":220,"officialTitle":221,"acronym":4,"eligibilityCriteria":222,"healthyVolunteers":16,"sex":17,"minAge":223,"maxAge":224,"enrollmentInfo":225,"targetDuration":4,"studyType":53,"phases":227,"briefSummary":228,"conditions":229,"keywords":232,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":237,"lastUpdatePostDateStruct":238,"startDateStruct":240,"completionDateStruct":242,"leadSponsor":244,"locationsCount":40},"100635116","effect-of-night-guard-use-on-masseter-muscle-thickness-in-children-with-bruxism-100635116","NCT07548502","Effect of Night Guard Use on Masseter Muscle Thickness in Children With Bruxism","Ultrasonographic Assessment of Masseter Muscles in Pediatric Bruxism: Effects of Night Guard Therapy at 3 and 6 Month Intervals","Inclusion Criteria:\n\n1. Children aged 10-12 years\n2. Diagnosis of bruxism based on parental report and clinical findings\n3. Willingness to participate\n4. Parental consent and child assent obtained\n\nExclusion Criteria:\n\n1. Missing posterior teeth causing unilateral chewing\n2. History of psychological disorders\n3. Neurological disorders or craniofacial abnormalities\n4. Use of medications affecting muscle activity\n5. Presence of skeletal malocclusions\n6. Ongoing orthodontic treatment","10 Years","12 Years",{"count":226,"type":22},20,[55],"This prospective study aims to evaluate the clinical findings of bruxism and masseter muscle thickness in children aged 10-12 years using ultrasonography, and to assess the effects of night guard use on these parameters over time.",[230,231],"Bruxism","Bruxism, Sleep-Related",[233,234,235,236],"Pediatric bruxism","Masseter muscle thickness","Ultrasonography","Night Guard","2026-04-23",{"date":239,"type":32},"2026-04-29",{"date":241,"type":32},"2026-03-15",{"date":243,"type":22},"2026-10",{"name":38,"class":39},{"id":246,"slug":247,"hasResults":11,"nctId":248,"briefTitle":249,"officialTitle":250,"acronym":4,"eligibilityCriteria":251,"healthyVolunteers":16,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":252,"targetDuration":4,"studyType":53,"phases":254,"briefSummary":255,"conditions":256,"keywords":259,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":265,"lastUpdatePostDateStruct":266,"startDateStruct":267,"completionDateStruct":269,"leadSponsor":271,"locationsCount":40},"100634667","aromatherapy-vs-music-therapy-for-anxiety-in-children-during-dental-radiography-100634667","NCT07542665","Aromatherapy vs Music Therapy for Anxiety in Children During Dental Radiography","Comparative Evaluation of the Effects of Aromatherapy and Music Therapy on Anxiety in Children Undergoing Oral Radiological Examination for the First Time","Inclusion Criteria:\n\n1. Children requiring panoramic radiography for dental examination\n2. No previous history of dental radiographic procedures\n3. Ability to understand and cooperate with the procedure\n4. Provision of written informed consent by parents or legal guardians\n\nExclusion Criteria:\n\n1. Presence of hearing or olfactory impairment\n2. Use of medications that may affect anxiety levels or heart rate\n3. Presence of systemic or neurological disorders\n4. Inability to cooperate with the study procedures\n5. Refusal of the child or parent\u002Fguardian to participate",{"count":253,"type":22},100,[55],"This study aims to evaluate and compare the effects of aromatherapy and music therapy on anxiety levels in children undergoing intraoral radiographic examination for the first time. Dental anxiety is a common problem in pediatric patients and can negatively impact cooperation and treatment outcomes.\n\nChildren included in the study will be randomly assigned to four groups: aromatherapy and music group, aromatherapy group, music therapy group, or control group. In the aromatherapy group, children will be exposed to a selected essential oil (lavender oil) before the radiographic procedure, while in the music therapy group, children will listen to calming music through a speaker. The group receiving both aromatherapy and music therapy will listen to music while being exposed to the essential oil. The control group will receive standard care without any additional intervention.\n\nAnxiety levels will be assessed before and after the radiographic procedure using the Facial Imaging Scale (FIS). Simultaneously, pulse rate will be measured before and after the procedure using a finger pulse oximeter. The primary aim is to determine whether aromatherapy, music therapy, or a combination of both is more effective in reducing anxiety compared to the control group.\n\nThe findings of this study are expected to contribute to the development of simple, non-invasive, and cost-effective methods to improve the comfort and cooperation of pediatric patients during dental radiographic procedures.",[257,258],"Dental Anxiety in Children","Pediatric Anxiety",[260,261,262,263,264],"Aromatherapy","Music therapy","Panoramic radiography","Dental anxiety","Pediatric dentistry","2026-04-21",{"date":159,"type":32},{"date":268,"type":32},"2026-03-05",{"date":270,"type":22},"2026-06",{"name":38,"class":39},{"id":273,"slug":274,"hasResults":11,"nctId":275,"briefTitle":276,"officialTitle":277,"acronym":4,"eligibilityCriteria":278,"healthyVolunteers":11,"sex":48,"minAge":49,"maxAge":110,"enrollmentInfo":279,"targetDuration":4,"studyType":53,"phases":281,"briefSummary":282,"conditions":283,"keywords":289,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":298,"lastUpdatePostDateStruct":299,"startDateStruct":301,"completionDateStruct":303,"leadSponsor":305,"locationsCount":40},"100626825","restrictive-vs-liberal-intraoperative-fluid-strategy-and-postoperative-outcomes-after-elective-cesarean-section-100626825","NCT07440667","Restrictive vs Liberal Intraoperative Fluid Strategy and Postoperative Outcomes After Elective Cesarean Section","A Prospective Randomized Controlled Trial Comparing Restrictive and Liberal Intraoperative Fluid Strategies on Postoperative Nausea and Vomiting and Gastrointestinal Recovery After Elective Cesarean Section Under Spinal Anesthesia","Inclusion Criteria:\n\n* Female patients aged 18-45 years\n* ASA physical status II\n* Scheduled for elective cesarean section under spinal anesthesia\n* Provision of written informed consent\n\nExclusion Criteria:\n\n* Emergency cesarean section\n* Preeclampsia or eclampsia\n* Known cardiac failure\n* Known renal failure\n* Known hepatic failure\n* Coagulopathy\n* Contraindication to spinal anesthesia\n* Conversion to general anesthesia\n* Major technical complications during spinal anesthesia\n* Refusal to participate",{"count":280,"type":22},160,[55],"Spinal anesthesia for elective cesarean section is frequently associated with hemodynamic instability and postoperative complications such as postoperative nausea and vomiting (PONV) and delayed gastrointestinal recovery. Although intraoperative fluid administration is routinely used to prevent spinal-induced hypotension, the optimal fluid strategy remains unclear. Both restrictive and liberal fluid approaches may influence maternal hemodynamics and postoperative outcomes through different physiological mechanisms.\n\nThis prospective, single-center, randomized controlled trial aims to compare restrictive (≤3 mL\u002Fkg\u002Fh) and liberal (\\>3 mL\u002Fkg\u002Fh) intraoperative crystalloid fluid strategies in patients undergoing elective cesarean section under spinal anesthesia. The primary outcome is the incidence of PONV within the first 24 hours postoperatively. Secondary outcomes include postdural puncture headache (PDPH), time to first flatus, hypotension frequency, and vasopressor requirements.",[284,285,286,287,288],"Cesarean Section","Postoperative Nausea and Vomiting (PONV)","Postdural Puncture Headache (PDPH)","Postoperative Ileus","Gastrointestinal Recovery",[284,290,291,292,293,294,295,288,296,297],"Spinal Anesthesia","Intraoperative Fluid Therapy","Restrictive Fluid Strategy","Liberal Fluid Strategy","Postoperative Nausea and Vomiting","Postdural Puncture Headache","Hypotension","Vasopressor Use","2026-03-07",{"date":300,"type":32},"2026-03-10",{"date":302,"type":32},"2026-03-04",{"date":304,"type":22},"2027-01-30",{"name":38,"class":39},{"id":307,"slug":308,"hasResults":11,"nctId":309,"briefTitle":310,"officialTitle":311,"acronym":4,"eligibilityCriteria":312,"healthyVolunteers":16,"sex":48,"minAge":49,"maxAge":313,"enrollmentInfo":314,"targetDuration":4,"studyType":53,"phases":315,"briefSummary":316,"conditions":317,"keywords":321,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":326,"lastUpdatePostDateStruct":327,"startDateStruct":329,"completionDateStruct":331,"leadSponsor":332,"locationsCount":40},"100624415","self-acupressure-for-primary-dysmenorrhea-and-premenstrual-symptoms-100624415","NCT07409337","Self-Acupressure for Primary Dysmenorrhea and Premenstrual Symptoms","Effects of Self-Acupressure on Primary Dysmenorrhea and Premenstrual Symptoms in Women Aged 18-30: A Randomized, Sham-Controlled, 6-Month Trial","Inclusion Criteria:\n\n* Female participants aged 18 to 30 years\n* Regular menstrual cycles (21-35 days)\n* Diagnosis of primary dysmenorrhea with moderate to severe menstrual pain\n* Presence of premenstrual symptoms consistent with premenstrual syndrome\n* Currently enrolled as a university student\n* Willingness to perform self-acupressure as instructed for approximately six menstrual cycles\n* Ability to understand the study procedures and provide written informed consent\n\nExclusion Criteria:\n\n* Secondary dysmenorrhea (e.g., endometriosis, uterine fibroids, pelvic inflammatory disease)\n* Current use of hormonal contraceptives or hormonal therapy within the past 3 months\n* Pregnancy or breastfeeding\n* Chronic gynecological, endocrine, or systemic disease that may affect menstrual pain or symptoms\n* Regular use of analgesic or anti-inflammatory medications outside menstruation\n* Prior formal training or regular practice of acupuncture or acupressure\n* Inability to comply with study procedures or follow-up schedule","30 Years",{"count":141,"type":22},[55],"This randomized, sham-controlled trial aims to evaluate the effects of self-administered acupressure on menstrual pain severity and premenstrual symptoms in women aged 18-30 years with primary dysmenorrhea. Participants will be randomly assigned to either a self-acupressure intervention group or a sham self-acupressure control group. The intervention will be applied during the premenstrual and menstrual periods over approximately six months. The primary outcome is the change in menstrual pain severity, and secondary outcomes include changes in premenstrual symptom severity, analgesic use, and menstruation-related activity limitation.",[318,319,320],"Primary Dysmenorrhea","Premenstrual Syndrome","Menstrual Pain",[150,322,323,324,325,156],"Dysmenorrhea","Premenstrual symptoms","Menstrual pain","Non-pharmacological treatment","2026-02-14",{"date":328,"type":32},"2026-02-18",{"date":330,"type":32},"2026-02-15",{"date":161,"type":22},{"name":38,"class":39},{"id":334,"slug":335,"hasResults":11,"nctId":336,"briefTitle":337,"officialTitle":338,"acronym":4,"eligibilityCriteria":339,"healthyVolunteers":16,"sex":17,"minAge":84,"maxAge":196,"enrollmentInfo":340,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":342,"conditions":343,"keywords":345,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":348,"lastUpdatePostDateStruct":349,"startDateStruct":351,"completionDateStruct":353,"leadSponsor":355,"locationsCount":40},"100614477","infants-with-primary-congenital-hypothyroidism-and-development-100614477","NCT07280104","Infants With Primary Congenital Hypothyroidism and Development","Investigation of Development Infants With Primary Congenital Hypothyroidism","Inclusion Criteria:\n\n* Those with primary congenital hypothyroidism who have been treated since the newborn period and are currently on treatment.\n* Infants born at term.\n* Between 6 and 18 months old.\n\nExclusion Criteria:\n\n* Infants with secondary congenital hypothyroidism,\n* Preterm infants,\n* Those with congenital infections or proven genetic alterations,\n* Infants diagnosed with metabolic, neurological, or genetic diseases,\n* Infants whose parents did not volunteer for the study",{"count":341,"type":22},40,"A review of the literature has focused primarily on the cognitive and motor development of children with congenital hypothyroidism, but no studies on sensory processing skills have been found. Considering the age range of the groups studied, studies conducted in the early stages of life are rare. This planned study aims to examine the neurological status, motor development, and sensory processing skills of infants aged 6-18 months, considering early synaptogenesis.",[344],"Congenital Hypothyroidism",[346,347,202,203],"Hypothyroidism","neurological status","2026-02-11",{"date":350,"type":32},"2026-02-12",{"date":352,"type":32},"2025-12-20",{"date":354,"type":22},"2026-12-20",{"name":38,"class":39},{"id":357,"slug":358,"hasResults":11,"nctId":359,"briefTitle":360,"officialTitle":361,"acronym":362,"eligibilityCriteria":363,"healthyVolunteers":11,"sex":17,"minAge":49,"maxAge":364,"enrollmentInfo":365,"targetDuration":4,"studyType":53,"phases":366,"briefSummary":367,"conditions":368,"keywords":371,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":382,"lastUpdatePostDateStruct":383,"startDateStruct":384,"completionDateStruct":385,"leadSponsor":386,"locationsCount":40},"100618213","postoperative-ozonated-oil-dressing-after-open-inguinal-hernia-repair-a-randomized-pilot-trial-100618213","NCT07328698","Postoperative Ozonated Oil Dressing After Open Inguinal Hernia Repair: A Randomized Pilot Trial","Effect of Postoperative Ozonated Oil Dressing on Early Wound Inflammation After Open Mesh Inguinal Hernia Repair: A Prospective Randomized Pilot Controlled Trial","OZONE-HERNIA","Inclusion Criteria:\n\n* Adults aged 18 to 75 years\n* ASA physical status I-III\n* Scheduled for elective, unilateral open inguinal hernia repair\n* Able to provide written informed consent\n\nExclusion Criteria:\n\n* Emergency inguinal hernia (incarcerated or strangulated)\n* Recurrent inguinal hernia\n* Concomitant surgical procedures during the same operation\n* Immunosuppression or long-term systemic steroid use\n* Use of anticoagulant or antiplatelet therapy\n* Known bleeding disorders\n* Active dermatologic disease at the surgical incision site\n* Pregnancy","75 Years",{"count":171,"type":22},[55],"This study looks at whether a special wound dressing containing ozonated oil can reduce early wound inflammation after open inguinal hernia surgery. Open inguinal hernia repair is a common operation, and although infection rates are low, many patients experience redness, swelling, tenderness, or discomfort at the surgical site during the first days after surgery.\n\nParticipants undergoing elective open inguinal hernia repair will be randomly assigned to receive either an ozonated oil-impregnated dressing or a standard sterile dressing after the operation. The main outcome is the level of wound inflammation measured on the third day after surgery. Other outcomes include wound temperature, pain levels, cosmetic healing, and wound-related problems during the first 30 days.\n\nThe ozonated oil used in this study is a CE-certified medical product that is already used in routine wound care. This pilot study aims to provide preliminary data to help determine whether ozonated oil dressing may improve early wound healing compared with standard care.",[369,370],"Inguinal Hernia Unilateral","Postoperative Wound Inflammation",[372,373,374,375,376,377,378,379,380,381],"Inguinal hernia repair","Open inguinal hernia surgery","Ozonated oil","Ozonated oil dressing","Postoperative wound inflammation","Surgical wound care","Topical ozone","Pilot randomized controlled trial","Clean surgical wound","Wound surface temperature","2026-02-10",{"date":348,"type":32},{"date":382,"type":32},{"date":68,"type":22},{"name":38,"class":39},{"id":388,"slug":389,"hasResults":11,"nctId":390,"briefTitle":391,"officialTitle":392,"acronym":4,"eligibilityCriteria":393,"healthyVolunteers":11,"sex":17,"minAge":394,"maxAge":4,"enrollmentInfo":395,"targetDuration":4,"studyType":53,"phases":397,"briefSummary":398,"conditions":399,"keywords":401,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":408,"lastUpdatePostDateStruct":409,"startDateStruct":411,"completionDateStruct":413,"leadSponsor":415,"locationsCount":4},"100623129","the-effect-of-acupressure-on-symptoms-in-elderly-adults-with-painful-diabetic-neuropathy-100623129","NCT07392619","The Effect of Acupressure on Symptoms in Elderly Adults With Painful Diabetic Neuropathy","Evaluation of the Effect of Acupressure Applied to Older Adults With Painful Diabetic Peripheral Neuropathy on Neuropathic Symptoms, Balance Confidence, Fear of Falling, and Quality of Life:","Inclusion Criteria:\n\nElderly individuals aged 65 years and older\n\nNo sensory impairment that would hinder communication\n\nCognitively capable of answering questions\n\nAble to walk independently or with an assistive device\n\nHave not previously received acupressure therapy for DPN\n\nDiagnosed with diabetic peripheral neuropathy (DPN) by a physician\n\nNo orthopedic problems\n\nProvide informed consent\n\nExclusion Criteria:\n\nNot providing informed consent\n\nHistory of non-diabetic neuropathy\n\nPhysician-diagnosed advanced cardiovascular, kidney, or liver disease\n\nBleeding tendency\n\nCerebrovascular disease\n\nHistory of medical conditions such as retinopathy or nephropathy\n\nPresence of open wounds, ulcers, or orthopedic problems on the feet\n\nInability to walk independently\n\nNot voluntarily agreeing to participate in the study","65 Years",{"count":396,"type":22},76,[55],"This project aims to evaluate the effects of acupressure applied to elderly individuals with painful diabetic peripheral neuropathy (DPN) on neuropathic symptoms, balance confidence, fear of falling, and quality of life. This project will be conducted using a mixed methodology integrating quantitative and qualitative methods. Elderly individuals will be randomly assigned to an acupressure or placebo control group. The acupressure group will receive a total of 10 sessions of acupressure over one month. Outcome measures include assessments of neuropathic pain and symptoms, balance confidence, fear of falling, and quality of life. Appropriate statistical tests will be used to analyze the quantitative data obtained from the study, while content analysis will be used for the qualitative data.",[400,120],"Painful Diabetic Peripheral Neuropathy (PDPN)",[402,403,404,405,406,407],"diabetic neuropathic symptoms","balance confidence","fear of falling","quality of life","olderly individuals","acupressure","2026-02-04",{"date":410,"type":32},"2026-02-06",{"date":412,"type":22},"2026-12-30",{"date":414,"type":22},"2028-09-05",{"name":38,"class":39},{"id":417,"slug":418,"hasResults":11,"nctId":419,"briefTitle":420,"officialTitle":421,"acronym":4,"eligibilityCriteria":422,"healthyVolunteers":16,"sex":17,"minAge":423,"maxAge":424,"enrollmentInfo":425,"targetDuration":4,"studyType":53,"phases":427,"briefSummary":428,"conditions":429,"keywords":431,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":436,"lastUpdatePostDateStruct":437,"startDateStruct":439,"completionDateStruct":441,"leadSponsor":443,"locationsCount":40},"100613220","effect-of-haptonomy-on-prenatal-attachment-and-fear-of-childbirth-in-primiparous-couples-100613220","NCT07263750","Effect of Haptonomy on Prenatal Attachment and Fear of Childbirth in Primiparous Couples","The Effect of Haptonomy Application for Primiparous Pregnant Women and Their Partners on Prenatal Attachment and Fear of Childbirth: A Randomized Controlled Study","Inclusion Criteria:\n\n* • At least a primary school graduate\n\n  * Between the 24th and 26th weeks of pregnancy\n  * According to calculations made by ultrasound based on the last menstrual period or, for pregnant women who do not know their last menstrual period, between the 24th and 26th weeks of pregnancy\n  * Primiparous\n  * No history of abortion\u002Fcurettage\n  * Planned\u002Fdesired pregnancy\n  * Desired baby gender\n  * Living with spouse\n  * Attended pregnancy classes\n  * Able to use technology such as computers and mobile phones to watch videos\n  * No barriers to understanding questions and responding\n  * No previous training on fear of childbirth or prenatal bonding\n  * Not having previously received education on haptonomy or practised haptonomy\n  * Not undergoing infertility treatment\n  * Being between the ages of 19 and 35\n\nExclusion Criteria:\n\n* • Be at least 26 weeks pregnant\n\n  * Live separately from spouse\n  * Have an unplanned\u002Funwanted pregnancy\n  * Not want the baby to be of a specific gender\n  * Not use technology\n  * Be a high-risk pregnancy\n  * Have previously received training on fear of childbirth and prenatal bonding\n  * Having previously received training in haptonomy and practised haptonomy\n  * Deciding to discontinue haptonomy practice after the study began and\u002For giving birth prematurely before completing the practice sessions","19 Years","35 Years",{"count":426,"type":22},144,[55],"This study was planned to evaluate the effect of haptonomy practice for primiparous pregnant women and their partners on prenatal attachment and fear of childbirth.",[58,430],"Prenatal Attachment",[61,432,433,434,435],"pregnant","father","prenatal attachment","haptonomia","2026-01-30",{"date":438,"type":32},"2026-02-03",{"date":440,"type":32},"2025-03-26",{"date":442,"type":22},"2026-04-01",{"name":38,"class":39},{"id":445,"slug":446,"hasResults":11,"nctId":447,"briefTitle":448,"officialTitle":449,"acronym":4,"eligibilityCriteria":450,"healthyVolunteers":11,"sex":17,"minAge":223,"maxAge":423,"enrollmentInfo":451,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":453,"conditions":454,"keywords":456,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":458,"lastUpdatePostDateStruct":459,"startDateStruct":461,"completionDateStruct":463,"leadSponsor":465,"locationsCount":40},"100620604","validity-and-reliability-of-the-behavioral-regulation-in-exercise-questionnaire-2-breq-2-in-adolescents-with-idiopathic-scoliosis-100620604","NCT07359781","Validity and Reliability of the Behavioral Regulation in Exercise Questionnaire-2 (BREQ-2) in Adolescents With Idiopathic Scoliosis","Assessment of Exercise Motivation in Adolescent Idiopathic Scoliosis: Validity and Reliability Study of the Behavioral Regulation in Exercise Questionnaire-2 (BREQ-2)","Inclusion Criteria:\n\n* Aged between 10 and 19 years\n* Diagnosed with adolescent idiopathic scoliosis\n* Receiving scoliosis-specific therapeutic exercise treatment for at least 2 months\n* Able to read and write in Turkish\n* Volunteered to participate in the study and provided informed consent\n\nExclusion Criteria:\n\n* Presence of congenital or neuromuscular scoliosis\n* Presence of systemic disease\n* Presence of syndromic conditions such as Marfan syndrome or Ehlers-Danlos syndrome",{"count":452,"type":22},95,"Adolescent idiopathic scoliosis (AIS) is a spinal condition that develops during adolescence and often requires long-term conservative treatment, including scoliosis-specific therapeutic exercises. The success of exercise-based treatment largely depends on adolescents' motivation to start and continue exercising. However, exercise motivation has not been adequately evaluated in adolescents with idiopathic scoliosis using validated tools specific to this population.\n\nThe Behavioral Regulation in Exercise Questionnaire-2 (BREQ-2) is a widely used questionnaire based on Self-Determination Theory that assesses different types of motivation toward exercise. Although the Turkish version of the BREQ-2 exists, its validity and reliability have not yet been examined in adolescents with idiopathic scoliosis.\n\nThe purpose of this study is to evaluate the validity and reliability of the Turkish version of the BREQ-2 in adolescents diagnosed with idiopathic scoliosis. Adolescents aged 10-19 years who have been participating in scoliosis-specific therapeutic exercise programs for at least two months will be invited to complete online questionnaires. The results of this study will help determine whether the BREQ-2 is an appropriate tool for assessing exercise motivation in this population and may support the development of individualized motivational strategies in scoliosis rehabilitation.",[455],"Adolescence Idiopathic Scoliosis",[457],"Adolescent idiopathic scoliosis, Exercise motivation, Behavioral regulation, Validity and reliability, Self-determination theory","2026-01-26",{"date":460,"type":32},"2026-01-28",{"date":462,"type":22},"2026-01",{"date":464,"type":22},"2026-12",{"name":38,"class":39},{"id":467,"slug":468,"hasResults":11,"nctId":469,"briefTitle":470,"officialTitle":471,"acronym":472,"eligibilityCriteria":473,"healthyVolunteers":11,"sex":17,"minAge":49,"maxAge":4,"enrollmentInfo":474,"targetDuration":4,"studyType":53,"phases":475,"briefSummary":476,"conditions":477,"keywords":480,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":483,"lastUpdatePostDateStruct":484,"startDateStruct":486,"completionDateStruct":488,"leadSponsor":490,"locationsCount":40},"100617525","tens-for-pain-and-sleep-after-hernia-surgery-100617525","NCT07319754","TENS for Pain and Sleep After Hernia Surgery","The Effect of Transcutaneous Electrical Nerve Stimulation (TENS) on Postoperative Pain and Sleep After Inguinal Hernia Surgery: A Randomized Controlled Trial","TENS-HERNIA","Inclusion Criteria:\n\n* Adults (≥18 years) undergoing elective inguinal hernia surgery\n\nAbility to provide informed consent\n\nWillingness to comply with study procedures\n\nExclusion Criteria:\n\n* History of epilepsy, cardiac pacemaker, or other contraindications to TENS\n\nSevere psychiatric or neurological disorders affecting pain or sleep assessment\n\nAllergy or intolerance to electrode materials\n\nPatients requiring emergency surgery\n\nInability to complete questionnaires (VAS, PSQI)",{"count":21,"type":22},[55],"This study evaluates whether Transcutaneous Electrical Nerve Stimulation (TENS) improves postoperative pain and sleep quality in adults undergoing inguinal hernia surgery. After surgery, participants will receive physician-supervised TENS or usual care. Pain intensity and sleep quality will be measured and compared between groups to assess the effectiveness and safety of TENS as a supportive recovery method.",[478,479,146],"Inguinal Hernia","Postoperative Pain",[481,479,146,482],"Inguinal hernia","Transcutaneous Electrical Nerve Stimulation (TENS)","2025-12-21",{"date":485,"type":32},"2026-01-06",{"date":487,"type":22},"2026-01-10",{"date":489,"type":22},"2026-10-10",{"name":38,"class":39},{"id":492,"slug":493,"hasResults":11,"nctId":494,"briefTitle":495,"officialTitle":496,"acronym":4,"eligibilityCriteria":497,"healthyVolunteers":16,"sex":17,"minAge":49,"maxAge":313,"enrollmentInfo":498,"targetDuration":4,"studyType":24,"phases":4,"briefSummary":500,"conditions":501,"keywords":503,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":509,"lastUpdatePostDateStruct":510,"startDateStruct":512,"completionDateStruct":513,"leadSponsor":514,"locationsCount":40},"100616916","investigating-the-relationships-between-body-composition-peripheral-muscle-strength-and-cough-force-in-healthy-young-adults-100616916","NCT07311837","Investigating the Relationships Between Body Composition, Peripheral Muscle Strength, and Cough Force in Healthy Young Adults","Investigating the Relationships Between Body Composition, Waist\u002FHip Ratio, Peripheral Muscle Strength, and Cough Force in Healthy Young Adults","Inclusion Criteria:\n\n* Individuals between the ages of 18-30 who volunteered to participate in the study\n\nExclusion Criteria:\n\n* Individuals who have a serious orthopedic, neurological or systemic disease that would prevent participation in the study and who do not volunteer to participate in the study",{"count":499,"type":22},46,"Introduction: Body mass index (BMI) is a key parameter used for obesity classification and the evaluation and monitoring of individuals' health status. Obesity, described by the World Health Organization as a major global epidemic, remains one of the most significant preventable and manageable conditions contributing to increased risks of cardiovascular and metabolic diseases. In addition to BMI, anthropometric measurements such as the waist-to-hip ratio are crucial indicators for risk assessment. While numerous studies in the literature have addressed the detrimental effects of obesity on respiratory functions, no study has specifically examined the relationship between cough strength-a vital respiratory parameter that reflects expiratory muscle strength- and body composition, waist-to-hip ratio, and peripheral muscle strength. Furthermore, although several studies have investigated the association between grip strength-a recognized indicator of peripheral muscle function in healthy individuals-and cough strength, no research to date has explored the relationship between pinch grip strength and cough strength.\n\nObjective: This study aims to investigate the relationships among body composition, waist-to-hip ratio, peripheral muscle strength, and cough strength in healthy young adults.\n\nMethods: This study was designed as a cross-sectional analysis. After providing detailed information about the study to potential participants, written informed consent will be obtained in duplicate from those who agree to participate. Following the completion of a general assessment form that captures demographic characteristics, each participant's height will be measured using a measuring tape. Body composition parameters-including body weight, BMI, body fat percentage, total body water percentage, muscle mass, basal metabolic rate, and metabolic age-will be assessed using a bioelectrical impedance analysis device (Tanita) available at our faculty.\n\nWaist and hip circumferences will be measured and used to calculate the waist-to-hip ratio for each participant. Peripheral muscle strength will be assessed using a hydraulic hand dynamometer and a pinch meter, while cough strength will be evaluated using a peak cough expiratory flow meter (PEF meter). All measurements will be repeated three times, with the best result recorded for analysis. Results: Statistical analysis will be performed using IBM SPSS Statistics version 30 (SPSS Inc., Chicago, IL, USA). Normality of continuous variables will be assessed through normality tests, coefficient of variation, and graphical representations (e.g., histograms, detrended plots). Descriptive statistics will be presented as mean ± standard deviation for normally distributed variables, and as median and interquartile range for non-normally distributed variables. Categorical variables will be expressed as percentages (%). Pearson correlation analysis will be used for normally distributed variables, and Spearman correlation analysis for non-normally distributed ones. The appropriate correlation coefficients and p-values will be reported. A p-value of \\\u003C0.05 will be considered statistically significant.\n\nDiscussion: Interpretation will be based on the results of the statistical analyses.",[502],"Healthy Young Adults",[504,505,506,507,508],"Body composition","Waist-to-hip ratio","Peripheral muscle strength","Peak expiratory flow","Cough strength","2025-12-16",{"date":511,"type":32},"2025-12-31",{"date":330,"type":22},{"date":241,"type":22},{"name":38,"class":39},{"id":516,"slug":517,"hasResults":11,"nctId":518,"briefTitle":519,"officialTitle":520,"acronym":521,"eligibilityCriteria":522,"healthyVolunteers":11,"sex":17,"minAge":49,"maxAge":4,"enrollmentInfo":523,"targetDuration":4,"studyType":53,"phases":524,"briefSummary":525,"conditions":526,"keywords":530,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":532,"lastUpdatePostDateStruct":533,"startDateStruct":535,"completionDateStruct":537,"leadSponsor":539,"locationsCount":40},"100616599","tens-for-anxiety-pain-and-satisfaction-after-laparoscopic-cholecystectomy-100616599","NCT07307703","TENS for Anxiety, Pain, and Satisfaction After Laparoscopic Cholecystectomy","Effects of Transcutaneous Electrical Nerve Stimulation (TENS) on Surgical Anxiety, Postoperative Pain, and Patient Satisfaction in Patients Undergoing Laparoscopic Cholecystectomy","TENS-LC","Inclusion Criteria:\n\n* Adults aged 18-65 years scheduled for elective laparoscopic cholecystectomy\n\nASA (American Society of Anesthesiologists) physical status classification I-II\n\nAbility to understand the study procedures and provide written informed consent\n\nNo contraindications to TENS application (e.g., intact skin at electrode placement sites)\n\nWillingness to comply with perioperative assessments (pain, anxiety, satisfaction scales)\n\nExclusion Criteria:\n\n* Patients with ASA III or higher physical status\n\nPresence of cardiac pacemaker or other implanted electrical devices\n\nHistory of epilepsy, severe neuropathy, or psychiatric disorders affecting pain\u002Fanxiety perception\n\nSkin lesions, infections, or dermatological conditions at electrode placement sites\n\nUse of analgesics, anxiolytics, or sedatives beyond standard perioperative protocols\n\nEmergency cholecystectomy or conversion to open surgery\n\nPregnant or breastfeeding women\n\nPatients unwilling or unable to provide informed consent",{"count":21,"type":22},[55],"This study is designed to evaluate whether Transcutaneous Electrical Nerve Stimulation (TENS) can improve recovery for patients undergoing laparoscopic gallbladder removal surgery (laparoscopic cholecystectomy). TENS is a non-invasive method that uses mild electrical currents applied through the skin to stimulate nerves.\n\nThe main goals of the study are to determine if TENS can:\n\nReduce surgical anxiety before and during the procedure\n\nDecrease postoperative pain after surgery\n\nImprove overall patient satisfaction with their surgical experience\n\nPatients who participate will receive standard surgical care, and some will also receive TENS therapy. Outcomes will be measured using patient questionnaires and clinical assessments during the hospital stay and follow-up period.\n\nBy comparing patients who receive TENS with those who do not, the study aims to provide evidence on whether this simple technique can enhance comfort and recovery after gallbladder surgery.",[527,479,528,529],"Gallstone Disease","Surgical Anxiety","Patient Satisfaction After Laparoscopic Cholecystectomy",[531,527,528,479,482],"Laparoscopic Cholecystectomy","2025-12-15",{"date":534,"type":32},"2025-12-29",{"date":536,"type":32},"2025-12-01",{"date":538,"type":22},"2026-09-30",{"name":38,"class":39},{"id":541,"slug":542,"hasResults":11,"nctId":543,"briefTitle":544,"officialTitle":545,"acronym":4,"eligibilityCriteria":546,"healthyVolunteers":11,"sex":48,"minAge":49,"maxAge":394,"enrollmentInfo":547,"targetDuration":4,"studyType":53,"phases":549,"briefSummary":550,"conditions":551,"keywords":4,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":554,"lastUpdatePostDateStruct":555,"startDateStruct":557,"completionDateStruct":559,"leadSponsor":561,"locationsCount":40},"100613062","the-effects-of-inspiratory-muscle-training-female-patients-with-fibromyalgia-100613062","NCT07261696","The Effects of Inspiratory Muscle Training Female Patients With Fibromyalgia","The Effects of Inspiratory Muscle Training on the Autonomic Nervous System and Clinical Symptoms in Female Patients With Fibromyalgia","Inclusion Criteria:\n\n* Be aged between 18 and 65 years old,\n* Have been diagnosed with fibromyalgia according to the 2010\u002F2016 ACR criteria,\n* Be female,\n* Have moderate pain lasting at least 3 months and defined as at least 30 mm on the 0-100 mm visual analogue scale (VAS).\n\nExclusion Criteria:\n\n* Presence of chronic heart disease,\n* Current use of narcotic drugs,\n* History of asthma or other chronic respiratory diseases,\n* Pregnancy,\n* Diabetes, kidney, adrenal, pituitary or thyroid disorders,\n* History of serious neurological or psychiatric disorders (e.g. mania, psychosis, suicidal tendencies, bipolar disorder, schizophrenia, autism spectrum disorders),\n* Neurodegenerative diseases (e.g. Parkinson's, Alzheimer's, Huntington's disease),\n* Head trauma, migraine,\n* Presence of active cardiac implants.",{"count":548,"type":22},51,[55],"Fibromyalgia is a chronic condition characterized by widespread musculoskeletal pain, fatigue, sleep disturbances, and psychological symptoms. Autonomic nervous system (ANS) dysfunction, marked by increased sympathetic and reduced parasympathetic activity, is considered one of its possible mechanisms. Although exercise is recommended in treatment, low motivation and fatigue often limit participation. Therefore, inspiratory muscle training (IMT), which targets the respiratory muscles, is seen as an easy-to-apply alternative.This randomized, controlled, double-blind study will be conducted at Niğde Ömer Halisdemir University Hospital. Fifty-one women aged 18-65 years who meet the 2010\u002F2016 ACR criteria for fibromyalgia will be randomly assigned to three groups: training (30% of maximal inspiratory pressure), sham (0-10%), and control (no training). ANS functions will be assessed using heart rate variability and the COMPASS-31 questionnaire. Pain, sleep quality, fatigue, anxiety, depression, and respiratory muscle strength will also be evaluated. Training will be performed with the Powerbreathe® device twice daily for six weeks.The study aims to investigate the effects of IMT on ANS functions in fibromyalgia and to explore its relationship with symptoms such as pain, fatigue, sleep disturbances, anxiety, and depression.",[552,553],"Fibromyalgia","Autonomic Dysfunction","2025-11-21",{"date":556,"type":32},"2025-12-03",{"date":558,"type":22},"2025-12-05",{"date":560,"type":22},"2026-12-05",{"name":38,"class":39},{"id":563,"slug":564,"hasResults":11,"nctId":565,"briefTitle":566,"officialTitle":567,"acronym":4,"eligibilityCriteria":568,"healthyVolunteers":16,"sex":17,"minAge":49,"maxAge":569,"enrollmentInfo":570,"targetDuration":4,"studyType":53,"phases":572,"briefSummary":573,"conditions":574,"keywords":576,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":580,"lastUpdatePostDateStruct":581,"startDateStruct":583,"completionDateStruct":585,"leadSponsor":587,"locationsCount":40},"100574965","effectiveness-of-asthma-education-program-based-on-the-roy-adaptation-model-100574965","NCT06766136","Effectiveness of Asthma Education Program Based on the Roy Adaptation Model","The Effect of Education Given to Asthmatic Individuals According to Roy Adaptation Model on Psychosocial Adjustment and Quality of Life","Inclusion Criteria:\n\n* Being in the age range of 18-64\n* Diagnosed with asthma for at least 6 months\n* To live in the city center\n* Asthma control test (ACT) score 24-20 (partial control) or ≤19 (uncontrolled)\n* Patients who voluntarily agreed to participate in the study\n\nExclusion Criteria:\n\n* Has a secondary chronic disease other than asthma\n* Diagnosed with neuropsychiatric illness\n* Individuals with inability to understand or speak Turkish and sensory problems that prevent communication","64 Years",{"count":571,"type":22},36,[55],"The aim of the study; to determine the effect of the education program given to individuals diagnosed with asthma based on Roy's adjustment model on their psychosocial adjustment to the disease and their quality of life.",[575],"Asthma Patients",[577,578,579],"Asthma patient","Psychosocial Adjustment","Life Quality","2025-06-13",{"date":582,"type":32},"2025-06-15",{"date":584,"type":32},"2024-12-20",{"date":586,"type":22},"2025-10-01",{"name":38,"class":39},{"id":589,"slug":590,"hasResults":11,"nctId":591,"briefTitle":592,"officialTitle":593,"acronym":594,"eligibilityCriteria":595,"healthyVolunteers":11,"sex":48,"minAge":196,"maxAge":424,"enrollmentInfo":596,"targetDuration":4,"studyType":53,"phases":598,"briefSummary":599,"conditions":600,"keywords":604,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":609,"lastUpdatePostDateStruct":610,"startDateStruct":612,"completionDateStruct":614,"leadSponsor":616,"locationsCount":40},"100579441","effect-of-targeted-mobilization-program-100579441","NCT06824337","Effect of Targeted Mobilization Program","Effect of Targeted Mobilization Program Applied After Caesarean Section Surgery on Care Outcomes: Randomized Controlled Study","Mobilization","Inclusion Criteria:\n\n* Between the ages of 18-35,\n* At least primary school graduate,\n* Giving birth at term\n* Having a live singleton pregnancy,\n* No risky pregnancy history (DVT, thromboembolism)\n* Women who can use a mobile phone\n\nExclusion Criteria:\n\n* Exclusion Criteria for the Study\n* Those who want to leave the study,\n* Undergoing emergency caesarean section,\n* Not recording walking distance\n* Women who cannot be interviewed within 24 hours of discharge\n* Women who develop maternal or neonatal complications after birth",{"count":597,"type":22},64,[55],"This study was planned to evaluate the effect of early mobilization training given to patients undergoing cesarean section in the preoperative period and targeted mobilization program applied after the surgery, on preventing gastrointestinal complications that may develop after the surgical intervention and participating in breastfeeding and baby care. The research will be conducted in experimental design. The research will begin after receiving written permission from Niğde Ömer Halisdemir University Ethics Committee, Niğde Provincial Health Directorate and Ömer Halisdemir Training and Research Hospital. Pregnant women who are between the ages of 18-35, who are at least a primary school graduate, who gave birth at term, who have a live singleton pregnancy, and who do not have a risky pregnancy history (DVT, thromboembolism) will be included in the study. Before starting the research, the study will begin by obtaining institutional permissions and written permission from the pregnant women. Personal Information Form prepared in line with the literature, postoperative gastrointestinal functions information form, postoperative abdominal distension diagnosis form, walking chart, VAS, LATCH Breastfeeding Diagnosis and Evaluation Scale and Breastfeeding Information Form data collection forms will be used to collect data. The data will be evaluated on a computer using the IBM SPSS Statistics 24 (Statistical Package for the Social Sciences for Windows) package program. Appropriate statistical analyzes will be used to evaluate the data",[601,602,603,116],"Caesarean Section","Mobility","Pain",[605,606,607,608],"Caesarean section","mobilization","pain","breastfeeding","2025-02-12",{"date":611,"type":32},"2025-02-13",{"date":613,"type":32},"2024-12-01",{"date":615,"type":22},"2025-04-01",{"name":38,"class":39},{"id":618,"slug":619,"hasResults":11,"nctId":620,"briefTitle":621,"officialTitle":622,"acronym":4,"eligibilityCriteria":623,"healthyVolunteers":16,"sex":17,"minAge":49,"maxAge":394,"enrollmentInfo":624,"targetDuration":4,"studyType":53,"phases":625,"briefSummary":626,"conditions":627,"keywords":630,"overallStatus":67,"whyStopped":4,"lastUpdateSubmitDate":636,"lastUpdatePostDateStruct":637,"startDateStruct":639,"completionDateStruct":641,"leadSponsor":643,"locationsCount":4},"100574392","the-effect-of-kinesio-taping-applied-to-operating-room-nurses-on-low-back-pain-fatigue-and-sleep-quality-100574392","NCT06758687","The Effect of Kinesio Taping Applied to Operating Room Nurses on Low Back Pain, Fatigue, and Sleep Quality","The Effect of Kinesio Taping Applied to Operating Room Nurses on Low Back Pain, Fatigue, and Sleep Quality: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Volunteering to participate in the study\n* Working in the operating room for at least one year\n\nExclusion Criteria:\n\n* Presence of conditions that will prevent the application of kinesio tape (excessive hair in the area where it is applied, skin rash, urticaria, etc.)\n* Necessity for continuous use of analgesics\n\nExclusion Criteria for the Study\n\n* Desire to leave the study while the study is ongoing\n* Allergic reaction or skin irritation to kinesio tape during the study\n* Use of analgesics during the period when kinesio tape is applied",{"count":253,"type":22},[55],"This study aims to determine the effects of kinesiology taping applied to operating room nurses on lower back pain, fatigue, and sleep quality. The research will be conducted using a randomized controlled experimental design with pre-test and post-test control groups. The universe of the study will consist of 100 operating room nurses working in a university hospital. The sample size has been calculated as a total of 84 nurses (Intervention group: 42; Control group: 42) based on power analysis calculations. The study will commence after obtaining the necessary permissions. Data collection will involve the use of the Descriptive Information Form, Visual Analog Scale, Quebec Back Pain Disability Scale, Visual Analogue Scale for Fatigue, and the Richards-Campbell Sleep Questionnaire. Participants who consent to the study will be administered the Descriptive Information Form, Visual Analog Scale, Quebec Back Pain Disability Scale, Visual Analogue Scale for Fatigue, and Richards-Campbell Sleep Questionnaire before the application of kinesiology tape. Subsequently, a physiotherapist from the research team will apply kinesiology tape to the paravertebral muscles using the muscle technique. As the literature suggests that the most suitable number of days for kinesiology tape application is four, participants will be instructed not to remove the tapes for four days. Additionally, participants will be informed that they can continue their daily activities and shower with the kinesiology tape on. The Visual Analog Scale will be applied to the participants at the end of the workday on the day of the kinesiology tape application and at the end of the workday for four days. At the end of the fourth day, all data collection tools will be applied. Seven days after the application, the scales will be filled out again by the nurses to determine if the effects of the kinesiology tape persist. Participants in the control group who agree to participate in the study will have data collected at the same time intervals as the intervention group participants using the same data collection tools. The Visual Analogue Scale will be administered to participants at the end of the day the data collection tools are filled out and at the end of the workday for four consecutive days. At the end of the fourth day, all data collection tools will be applied again. Seven days after the application, all scales will be refilled by the nurses..",[628,629],"Lower Back Pain","Kinesio Taping",[631,632,633,634,635],"Operating room nurse","lower back pain","sleep quality","fatigue","kinesio taping","2025-01-03",{"date":638,"type":32},"2025-01-06",{"date":640,"type":22},"2025-01",{"date":642,"type":22},"2025-12",{"name":38,"class":39},{"id":645,"slug":646,"hasResults":11,"nctId":647,"briefTitle":648,"officialTitle":649,"acronym":650,"eligibilityCriteria":651,"healthyVolunteers":16,"sex":48,"minAge":49,"maxAge":424,"enrollmentInfo":652,"targetDuration":4,"studyType":53,"phases":654,"briefSummary":655,"conditions":656,"keywords":659,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":661,"lastUpdatePostDateStruct":662,"startDateStruct":664,"completionDateStruct":666,"leadSponsor":668,"locationsCount":40},"100570541","information-and-progressive-relaxation-exercises-100570541","NCT06708585","Information and Progressive Relaxation Exercises","Effects of Planned Pre-Cesarean Information and Progressive Relaxation Exercises on Surgical Fear, Anxiety, Postpartum Comfort and Pain Levels of Primigravida Women: A Randomized Controlled Trial","RKÇ","Inclusion Criteria:\n\n* Between the ages of 18-35,\n* Primigravida,\n* Applied for planned cesarean section,\n* Live singleton pregnancy,\n* Spinal anesthesia planned,\n\nExclusion Criteria:\n\n* Women who develop postpartum maternal or neonatal complications\n* Receiving general anesthesia.",{"count":653,"type":22},68,[55],"This study was planned to determine the effect of information and progressive relaxation exercises before planned cesarean section on surgical fear, anxiety, postpartum comfort and pain levels.The research will be conducted in experimental design. The research will begin after receiving written permission from Niğde Ömer Halisdemir University Ethics Committee, Niğde Provincial Health Directorate and Ömer Halisdemir Training and Research Hospital. Pregnant women who are between the ages of 18-35, who are on Primigravida, who apply for a planned cesarean section, who have a live single pregnancy, and who are planned for spinal anesthesia will be included in the study. Before starting the research, the study will begin by obtaining institutional permissions and written permission from the pregnant women. Pre-Assessment Form, Personal Information Form, State Anxiety Scale, Surgical Fear Scale, Postpartum Comfort Scale will be used to collect data. The data will be evaluated on a computer using the IBM SPSS Statistics 24 (Statistical Package for the Social Sciences for Windows) package program. Appropriate statistical analyzes will be used to evaluate the data.",[601,657,658,603],"Fear","Anxiety",[660],"Cesarean section, fear, anxiety, comfort, pain","2024-11-25",{"date":663,"type":32},"2024-11-27",{"date":665,"type":32},"2024-09-19",{"date":667,"type":22},"2025-03-30",{"name":38,"class":39},{"id":670,"slug":671,"hasResults":11,"nctId":672,"briefTitle":673,"officialTitle":674,"acronym":4,"eligibilityCriteria":675,"healthyVolunteers":11,"sex":48,"minAge":49,"maxAge":394,"enrollmentInfo":676,"targetDuration":4,"studyType":53,"phases":678,"briefSummary":679,"conditions":680,"keywords":683,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":687,"lastUpdatePostDateStruct":688,"startDateStruct":690,"completionDateStruct":692,"leadSponsor":694,"locationsCount":40},"100558047","intermittent-fasting-and-mediterranean-diet-in-patient-with-multiple-sclerosis-100558047","NCT06546033","Intermittent Fasting and Mediterranean Diet in Patient With Multiple Sclerosis","Determination of the Effects of Intermittent Fasting and Mediterranean Diet on Quality of Life, Circadian Rhythm and Appetite Markers in Patient With Multiple Sclerosis","Inclusion Criteria:\n\n* To apply to the neurology outpatient clinic, to be a female between the ages of 18-65 who has been diagnosed with MS by a physician\n* Not being in the attack period\n* Not being in menopause Not being diagnosed with any autoimmune system disease other than -MS that may adversely affect the study,\n* Not following the Mediterranean diet and intermittent fasting programmes in the last three months,\n* Not being diagnosed with an eating behaviour disorder,\n* Not having any communication problems,\n* Signing the informed consent form,\n* Brain MRI within the last three months,\n* Not to be pregnant and lactating\n* No physical disability No history of cancer\n* Body Mass Index between 18,5 kg\u002Fm2- 29,9 kg\u002Fm2,\n* Not losing 5% and\u002For more body weight in the last month\n\nExclusion Criteria:\n\n* Having a diagnosis of autoimmune system disease that may adversely affect working outside of -MS,\n* To be in the attack period-Being under 18 years of age and over 65 years of age\n* Being in menopause-Mediterranean diet and intermittent fasting feeding programmes within the last three months,\n* Diet therapy that has an effect on the autoimmune system within the last three months,\n* Being diagnosed with eating behaviour disorder,\n* Having any communication problems,- Not signing the informed consent form,\n* Failure to adapt to the work during the working period, to be in a situation\u002Fbehaviour that may adversely affect the work,\n* To have applied any nutritional intervention during the last three months prior to the study,\n* Taking supplements such as selenium, zinc, iron, vitamin D and\u002For B12, which may affect the course of the study,\n* To have received cancer treatment and \u002F or to be receiving cancer treatment,\n* Other neurological diseases (e.g. Parkinson's, epilepsy, Alzheimer's),\n* Diagnosed with a disease lasting more than 4 months in the last 12 months and other specialised dietary \u002F compositionally different dietary patterns (e.g. high protein, ketogenic, low energy content \\\u003C 1000 kcal\u002Fday),\n* Body Mass Index \\\u003C18.5 kg\u002Fm2 or \\>30 kg\u002Fm2\n* Losing 5% and\u002For more body weight in the last month,\n* Having a physical disability",{"count":677,"type":22},34,[55],"When the literature was reviewed, there is no study in which the effects of intermittent fasting and Mediterranean diet on quality of life, sleep, circadian rhythm and appetite hormones leptin and ghrelin levels in MS patients were evaluated and the two diet types were comparatively examined in terms of all these parameters.",[681,682],"Multiple Sclerosis","Intermittent Fasting",[684,685,686,682],"Multiple sclerosis","circadian rhythm","mediterranean diet","2024-08-05",{"date":689,"type":32},"2024-08-09",{"date":691,"type":32},"2024-05-02",{"date":693,"type":22},"2026-12-02",{"name":38,"class":39},""]