[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Northern Orthopaedic Division, Denmark\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":68},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,41],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":4},"100608502","intraarticular-gold-microparticles-for-knee-osteoarthritis-100608502",false,"NCT07202390","Intraarticular Gold Microparticles for Knee Osteoarthritis","Intraarticular Gold Microparticles for Knee Osteoarthritis. A Randomized Trial","Inclusion Criteria:\n\n* more than 6 months of knee pain without efficacy on pain of conservative treatment, radiographic knee osteoarthritis according to Kellgren-Lawrence grade 1-4, and age ≥18years\n\nExclusion Criteria:\n\n* malalignment, indication for knee replacement surgery, malignancy, active infection and antibiotic treatment, active treatment with steroids, biological or other anti-Rheumatic medication, inability to comply with the protocol, inadequacy in the written and spoken national language","ALL","18 Years",{"count":19,"type":20},240,"ESTIMATED","INTERVENTIONAL",[23],"NA","The investigators have shown in three pilot studies that intra-articular metallic gold microparticles can reduce knee osteoarthritis pain for up to two years. These results are noteworthy considering the growing number of older adults who suffer from osteoarthritis pain, which contributes to increased demand on healthcare resources. Demonstrating effective treatment could alleviate this burden for a significant portion of the aging population.\n\nThe specific aim is to evaluate whether intra-articular metallic gold microparticles are superior to placebo in reducing the need for additional treatment in patients with knee osteoarthritis within one year. The investigators will test the hypothesis that intra-articular metallic gold microparticles reduce subsequent treatment events by more than 50% compared to placebo during this period.",[26],"Knee Osteoarthritis",[28],"Intraarticular gold; knee osteoarthritis","NOT_YET_RECRUITING","2025-09-29",{"date":32,"type":33},"2025-10-01","ACTUAL",{"date":35,"type":20},"2026-02-01",{"date":37,"type":20},"2029-02-01",{"name":39,"class":40},"Northern Orthopaedic Division, Denmark","OTHER",{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":4,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":16,"minAge":48,"maxAge":4,"enrollmentInfo":49,"targetDuration":4,"studyType":21,"phases":51,"briefSummary":52,"conditions":53,"keywords":55,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":66,"locationsCount":67},"100415100","dual-mobility-cup-versus-unipolar-cup-100415100","NCT04685239","Dual Mobility Cup Versus Unipolar Cup","Risk of Dislocation After Total Hip Replacement: Dual Mobility Cup vs. Unipolar Cup. A Randomized Controlled Trial With Patients ≥65 Years Operated for Hip Osteoarthritis With Primary Total Hip Replacement (THR).","Inclusion Criteria:\n\n* Patients with hip arthritis who are amenable to surgery with THR and age ≥ 65 years referred to the Department of Orthopedic Surgery at either Section Farsø, Frederikshavn Hospital or Aalborg University Hospital. Patients who are willing to participate in the trial and who give their written, informed consent after receiving oral and written information.\n\nExclusion Criteria:\n\n* Patients who do not wish to participate.\n* Sequelae of Calvé-Legg-Perthes' disease, caput necrosis, epiphysiolysis.\n* Proximal femoral or acetabular fracture.\n* Hip dysplasia with subluxation Crowe types III and IV.\n* Earlier hip bone surgery (excluding arthroscopic surgery).\n* Elective bilateral surgery.\n* If the patient's bone morphology is unsuitable for a cemented Exeter® femoral stem.\n* Patients with no e-mail.","65 Years",{"count":50,"type":20},1000,[23],"The general purpose of this study is to examine whether the dual mobility cup (Novae® Serf) reduces the number of hip dislocations after total hip replacement, both early dislocation (≤1 year) and late dislocation (\\>1 year) after primary THR compared with a conventional cup design (Trabecular MetalTM Modular Acetabular System).",[54],"Dislocation, Hip",[56,57,58],"dislocation, hip","thr","dual mobility cup","2023-03-24",{"date":61,"type":33},"2023-03-27",{"date":63,"type":20},"2023-04-01",{"date":65,"type":20},"2035-12",{"name":39,"class":40},1,""]