[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Notos Medical Limited\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":43},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":31,"whyStopped":4,"lastUpdateSubmitDate":32,"lastUpdatePostDateStruct":33,"startDateStruct":36,"completionDateStruct":38,"leadSponsor":40,"locationsCount":5},"100623439","feasibility-of-upper-airway-stimulation-in-osa-100623439",false,"NCT07396649","Feasibility of Upper Airway Stimulation in OSA","Feasibility of Non-invasive Electrical Nerve Stimulation of the Upper Airway in Patients With Obstructive Sleep Apnoea","Inclusion Criteria:\n\n* Obstructive sleep apnoea diagnosis with an AHI of 15-50 events\u002Fhour recorded in the baseline polysomnography (PSG)\n* BMI \\\u003C 32 kg\u002Fm²\n* Age \\> 18 years old\n* Able to read, write, and speak Dutch with acceptable visual and auditory acuity\n* Able and willing to provide informed consent\n\nExclusion Criteria:\n\n* Presence of a cardiac pacemaker or implantable cardiac defibrillator or ventriculoperitoneal shunt\n* Central (non-obstructive) AHI episodes \\>5 events\u002Fhour recorded in the baseline PSG\n* Inability to sleep supine\n* Pregnancy\n* Inability to undergo DISE\n* Inability or unwillingness to shave under and around their chin and neck if appropriate\n* Known inability to complete PSG with a total sleep time of \\> 4 hours\n* The use of other neurostimulatory devices\n* A diagnosis of periodic leg movement disorder\n* Awake resting arterial oxygen saturation \\\u003C93% (suggesting possible hypoventilation)\n* Unstable, untreated coronary or peripheral artery disease\n* Severe arterial hypertension defined as a resting blood pressure (BP) of \\>180\u002F110mmHg\n* Currently employed as a professional driver\n* Any previous sleep-related driving accident\n* A past or current condition that in the opinion of the investigator contraindicates enrolment (e.g. chronic substance abuse, severe psychiatric disorders)","ALL","19 Years",{"count":19,"type":20},15,"ESTIMATED","INTERVENTIONAL",[23],"NA","Project Breathe 1 is a short-duration (5 month) pilot investigation to assess the safety and tolerability of non-invasive electrical stimulation in adults with obstructive sleep apnoea. The investigation is an unblinded, uncontrolled, single arm design.",[26],"Obstructive Sleep Apnoea (OSA)",[28,29,30],"obstructive sleep apnoea","OSA","sleep apnoea","RECRUITING","2026-02-05",{"date":34,"type":35},"2026-02-09","ACTUAL",{"date":37,"type":35},"2026-01-29",{"date":39,"type":20},"2026-07",{"name":41,"class":42},"Notos Medical Limited","INDUSTRY",""]