[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"October 6 University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":461},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,20,0,[8,42,65,89,113,134,158,186,205,227,246,267,289,308,330,355,381,400,420,442],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100623993","effect-of-scanning-technology-on-the-accuracy-of-digitally-customized-intraradicular-attachments-100623993",false,"NCT07403851","Effect of Scanning Technology on the Accuracy of Digitally Customized Intraradicular Attachments","Effect of Scanning Technology on the Accuracy of Digitally Customized Intraradicular Attachments: A Cross Overstudy","Inclusion Criteria:\n\n1. Patients aged 18-65 years.\n2. Endodontically treated teeth requiring intra-radicular attachments.\n3. Adequate oral hygiene .\n4. Periodontally Compromised Teeth: When some teeth have reduced bone support but can still be maintained as overdenture abutments with proper treatment.\n\nExclusion Criteria:\n\n1. Severely Compromised Remaining Teeth: If the remaining teeth have poor prognosis due to extensive decay or severe periodontal disease.\n2. Severe Bone Loss Around Abutment Teeth: If the remaining teeth do not provide adequate support, they may fail early, leading to additional complications.\n3. Severe Malocclusion: Where occlusal discrepancies make overdenture placement difficult.\n4. Limited inter-arch Space: cann't accommodate the overdenture components. 5 . Poor Oral Hygiene: increase the risk of decay or periodontal issues in retained abutments.",true,"ALL","18 Years","65 Years",{"count":21,"type":22},60,"ESTIMATED","INTERVENTIONAL",[25],"NA","This study aims to evaluate the accuracy of intra-radicular attachments fabricated by direct scanning using three different scanners in vivo. The primary outcome will be the accuracy of the fabricated attachments, while secondary outcomes will includepatient-reported comfort during procedure of taking intraradicular attachment conventional impression and direct scanning.",[28],"Scanning Devices","RECRUITING","2026-06-29",{"date":32,"type":33},"2026-07-01","ACTUAL",{"date":35,"type":33},"2026-05-01",{"date":37,"type":22},"2026-08-01",{"name":39,"class":40},"October 6 University","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":49,"targetDuration":4,"studyType":23,"phases":51,"briefSummary":52,"conditions":53,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":57,"lastUpdatePostDateStruct":58,"startDateStruct":60,"completionDateStruct":62,"leadSponsor":64,"locationsCount":41},"100637310","injectable-platelet-rich-fibrin-with-minimally-invasive-non-surgical-technique-in-treatment-of-periodontal-intrabony-defects-100637310","NCT07613606","Injectable Platelet-Rich Fibrin With Minimally Invasive Non-Surgical Technique in Treatment of Periodontal Intrabony Defects","Injectable Platelet-Rich Fibrin (i-PRF) With Minimally Invasive Non-Surgical Technique in Treatment of Periodontal Intrabony Defects: A Randomized Clinical Trial","Inclusion Criteria:\n\n* Patients of both genders \\>18 years old, medically free of systemic diseases affecting periodontal regeneration.\n* Diagnosis of 'periodontitis' stage III (grades B or C).\n* Single-rooted and multi-rooted vital teeth in either the maxilla or the mandible.\n* Presence of comparable bilateral two- or three-walled intrabony defects \\[probing pocket depth (PPD), \\> 5 mm with intrabony defect depth ≥ 3 mm, from the alveolar crest to the defect base, at screening radiograph\\] not in a furcation-involved tooth.\n\nExclusion Criteria:\n\n* Patients with systemic illness known to affect the outcome of periodontal therapy, including diabetes, immune deficiencies, etc.\n* Pregnant and lactating women\n* Current use of any form of tobacco.\n* Non-surgical periodontal treatment in the past 6 months, or surgical periodontal treatment in the past 12 months.\n* Degree 2 or 3 mobility of the involved sites.6.\n* Presence of periapical pathology, acute infection, or subgingival restoration which could interfere with clinical measurements.",{"count":50,"type":22},40,[25],"This study aims to clinically and radiographically evaluate the adjunctive effect of injectable platelet-rich fibrin (i-PRF) used in combination with a minimally invasive non-surgical technique for the regenerative treatment of intrabony periodontal defects.",[54,55,56],"Platelet-Rich Fibrin","Minimally Invasive Non-Surgical Technique","Periodontal Intrabony Defects","2026-05-21",{"date":59,"type":33},"2026-05-29",{"date":61,"type":33},"2026-03-01",{"date":63,"type":22},"2026-12-01",{"name":39,"class":40},{"id":66,"slug":67,"hasResults":11,"nctId":68,"briefTitle":69,"officialTitle":70,"acronym":4,"eligibilityCriteria":71,"healthyVolunteers":11,"sex":17,"minAge":72,"maxAge":73,"enrollmentInfo":74,"targetDuration":4,"studyType":23,"phases":76,"briefSummary":78,"conditions":79,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":41},"100634298","phase-2-effect-of-montelukast-on-inflammatory-markers-and-cardiac-injury-in-patients-with-acute-myocardial-infarction-100634298","NCT07537868","Effect of Montelukast on Inflammatory Markers and Cardiac Injury in Patients With Acute Myocardial Infarction","Effect of Montelukast on Inflammatory Markers and Cardiac Injury in Patients With Acute Myocardial Infarction: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Age 30-75 years Diagnosed with STEMI within 6 hours of symptom onset Undergoing PCI or thrombolysis Eligible for standard ACS therapy signed Informed consent\n\nExclusion Criteria:\n\n* Chronic use of anti-inflammatory drugs\n* Severe hepatic or renal impairment\n* Hypersensitivity to Montelukast\n* Autoimmune or inflammatory diseases\n* Cardiogenic shock, severe heart failure or structural complications such as papillary muscle rupture\n* Having received cardiopulmonary resuscitation\n* Severe and inadequately controlled hypertension\n* History of myocardial infarction\n* Concomitant active bleeding or visceral hemorrhage\n* Concomitant malignant tumors, lymphomas, leukemias, or other diseases\n* gastrointestinal surgery within the past 4 weeks that may affect the absorption of the investigational drug\n* Family history of psychiatric disorders\n* Pregnancy or lactation\n* Participation in another clinical trial","30 Years","75 Years",{"count":75,"type":22},80,[77],"PHASE2","This is a randomized controlled clinical trial designed to evaluate the therapeutic effects of Montelukast in patients diagnosed with Acute Myocardial Infarction (AMI). The study aims to investigate whether the administration of Montelukast influences inflammatory markers and the extent of cardiac injury following a heart attack.Participants will be randomly assigned to receive either the active medication or a placebo to provide high-quality evidence regarding the drug's potential cardioprotective and anti-inflammatory properties. The trial is conducted through the Faculty of Pharmacy and Faculty of Medicine at Mansoura University",[80],"Acute Myocardial Infarction (AMI)","2026-05-04",{"date":83,"type":33},"2026-05-08",{"date":85,"type":33},"2026-04-20",{"date":87,"type":22},"2027-10",{"name":39,"class":40},{"id":90,"slug":91,"hasResults":11,"nctId":92,"briefTitle":93,"officialTitle":94,"acronym":4,"eligibilityCriteria":95,"healthyVolunteers":11,"sex":96,"minAge":97,"maxAge":19,"enrollmentInfo":98,"targetDuration":4,"studyType":23,"phases":100,"briefSummary":101,"conditions":102,"keywords":4,"overallStatus":105,"whyStopped":4,"lastUpdateSubmitDate":106,"lastUpdatePostDateStruct":107,"startDateStruct":109,"completionDateStruct":110,"leadSponsor":112,"locationsCount":41},"100635287","truness-of-full-arch-impressions-in-all-on-x-cases-100635287","NCT07550725","Truness of Full Arch Impressions in All on x Cases","Trueness of Full-Arch Impressions Using Photogrammetry, Splinted Digital Scan Bodies Versus Conventional Open-Tray Techniques in the All-on-x Prosthesis","Inclusion Criteria:\n\n* Adults aged 45-65 years.\n* Fully edentulous or partially edentulous maxilla requiring full-arch rehabilitation.\n* Sufficient maxillary bone volume to support at least four implants according to the All-on-X protocol.\n* Systemically healthy patients with no contraindications to dental implant surgery (ASA I-II classification).\n* Demonstrated ability to maintain adequate oral hygiene\n* Willingness to participate in the study and comply with follow-up visits and required maintenance protocols.\n* Patients seeking a fixed, implant-supported prosthesis for the maxilla due to missing teeth and inability to use removable prostheses effectively.\n* Acceptable radiographic findings with no signs of pathology, infection, or significant anatomical limitations.\n\nExclusion Criteria:\n\n* Uncontrolled systemic diseases (e.g., uncontrolled diabetes, osteoporosis, immunosuppressive disorders)\n* History of radiation therapy to the head and neck region\n* Active periodontal disease or untreated caries\n* Maxillary cysts, tumors, or pathologies\n* Poor oral hygiene or inability to maintain postoperative care\n* Insufficient bone volume for All-on-X without extensive grafting\n* Maxillary sinus pathology or oroantral fistula\n* Psychiatric illness or cognitive impairment affecting compliance\n* Bruxism or parafunctional habits\n* Pregnant or lactating women\n* History of implant failure or titanium allergy\n* Use of bisphosphonates or antiresorptive medications\n* Heavy smoking (\\>10 cigarettes\u002Fday)\n* Inability or unwillingness to attend follow-up visits\n* Diagnosed or symptomatic temporomandibular joint disorders (pain, clicking, locking, limited opening)","MALE","55 Years",{"count":99,"type":22},11,[25],"This study aims to compare the trueness and precision of three impression methodologies photogrammetry, digital intraoral scanning with splinted scan bodies, and conventional open tray impressions in the context of the All-on-X treatment concept. This will provide valuable evidence for clinicians considering digital workflows for implant-supported prostheses. Does the use of photogrammetry and digital impression techniques with splinted scan bodies result in improved accuracy in implant position transfer in the All-on-X concept compared to conventional open tray impressions?",[103,104],"Truness of Impression Techniques in All on x Cases","Trueness of Full Arch Implant Prosthesis Impression","NOT_YET_RECRUITING","2026-05-02",{"date":108,"type":33},"2026-05-07",{"date":35,"type":22},{"date":111,"type":22},"2026-10-01",{"name":39,"class":40},{"id":114,"slug":115,"hasResults":11,"nctId":116,"briefTitle":117,"officialTitle":117,"acronym":4,"eligibilityCriteria":118,"healthyVolunteers":11,"sex":17,"minAge":119,"maxAge":120,"enrollmentInfo":121,"targetDuration":4,"studyType":23,"phases":123,"briefSummary":124,"conditions":125,"keywords":4,"overallStatus":105,"whyStopped":4,"lastUpdateSubmitDate":127,"lastUpdatePostDateStruct":128,"startDateStruct":130,"completionDateStruct":131,"leadSponsor":133,"locationsCount":4},"100635390","effect-of-lumbar-spine-correction-training-on-postural-awareness-and-stability-in-patients-with-low-back-pain-100635390","NCT07552064","Effect of Lumbar Spine Correction Training on Postural Awareness and Stability in Patients With Low Back Pain","Inclusion Criteria:\n\n* Their ages range from 25 to 45 years.\n* Both sex\n* Low back pain for more than 6 months.\n* Normal body mass index (18.5 - 29 Kg\u002Fm2).\n\nExclusion Criteria:\n\n* Patients with any other Neurological deficits, psychiatric disease lumbar myelopathy, Cognitive problems, vertebral fractures and previous history of spine or lumbar surgery.\n* Clinical instability, recent trauma\n* Structural abnormalities of the spine, osteoporosis, and spasmodic torticollis.\n* Inflammatory or other specific disorders of spina such as ankylosing spondylitis and rheumatoid arthritis","25 Years","45 Years",{"count":122,"type":22},30,[25],"PURPOSE: to investigate The Efficacy of lumbar spine correction training on postural awareness and stability in patients with low back pain. Patients with low back pain demonstrate impairments in function and range of motion to deficits in patient's quality of life.\n\nHYPOTHESES: It will be hypothesized that there will be no statically Effect of lumbar spine correction training on postural awareness and stability in patients with low back pain",[126],"Low Back Pain","2026-04-26",{"date":129,"type":33},"2026-04-30",{"date":129,"type":22},{"date":132,"type":22},"2026-07-30",{"name":39,"class":40},{"id":135,"slug":136,"hasResults":11,"nctId":137,"briefTitle":138,"officialTitle":139,"acronym":4,"eligibilityCriteria":140,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":141,"targetDuration":4,"studyType":23,"phases":142,"briefSummary":143,"conditions":144,"keywords":146,"overallStatus":105,"whyStopped":4,"lastUpdateSubmitDate":85,"lastUpdatePostDateStruct":153,"startDateStruct":155,"completionDateStruct":156,"leadSponsor":157,"locationsCount":4},"100634587","effect-of-scanning-technology-on-internal-fit-of-digitally-customized-intra-radicular-attachments-100634587","NCT07541625","Effect of Scanning Technology on Internal Fit of Digitally Customized Intra-radicular Attachments","Evaluation of Marginal and Internal Fit of Intraradicular Attachments Fabricated byDirect &Indirect Scanning Techniques","Inclusion Criteria:\n\n* Endodontically treated teeth requiring intraradicular attachments.\n* Adequate oral hygiene.\n* Partially edentulous cases where compromised remaining teethcannot serve as abutments for traditional removable partial dentures (RPDs). -\n* Periodontally compromised teeth that can still be maintainedasoverdenture abutments with proper treatment.\n\nExclusion Criteria:\n\n1. Severely compromised remaining teeth with poor prognosis duetoextensive decay or severe periodontal disease.\n2. Severe bone loss around abutment teeth.\n3. Severe malocclusion making overdenture placement difficult.\n4. Limited inter-arch space that cannot accommodate overdenturecomponents. 5. Poor oral hygiene increasing the risk of decay or periodontal issues.\n\n6\\. Patients medically unfit for any surgical procedure.",{"count":21,"type":22},[25],"This study aims to evaluate the marginal and internal fit of intra-radicular attachments fabricated by direct scanning using two different intraoral scanners compared to indirect scanning of conventional impressions.",[145],"Partially Edentulous Jaw",[147,148,149,150,151,152],"Intraradicular attachments","Marginal fit","Internal fit","Intraoral scanner","Scan accuracy","Prosthetic fit",{"date":154,"type":33},"2026-04-23",{"date":129,"type":22},{"date":132,"type":22},{"name":39,"class":40},{"id":159,"slug":160,"hasResults":11,"nctId":161,"briefTitle":162,"officialTitle":162,"acronym":4,"eligibilityCriteria":163,"healthyVolunteers":16,"sex":164,"minAge":18,"maxAge":165,"enrollmentInfo":166,"targetDuration":4,"studyType":23,"phases":168,"briefSummary":169,"conditions":170,"keywords":173,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":178,"lastUpdatePostDateStruct":179,"startDateStruct":181,"completionDateStruct":183,"leadSponsor":185,"locationsCount":41},"100603147","impact-of-underwater-exercise-versus-regular-aerobic-exercise-on-quality-of-life-and-power-of-muscle-100603147","NCT07132736","Impact of Underwater Exercise Versus Regular Aerobic Exercise on Quality of Life and Power of Muscle","Inclusion Criteria:\n\n1. BMI\\> 25\n2. low muscle power\n3. low quality of life\n4. general fatigue\n\nExclusion Criteria:\n\n1. BMI\\\u003C 25\n2. Polycystic ovarian syndrome\n3. Chronic pelvic pain\n4. Lumbar disc","FEMALE","50 Years",{"count":167,"type":22},100,[25],"To investigate the Impact of underwater exercise versus regular aerobic exercise on quality of life and power of muscle",[171,172],"Muscle Weakness | Patient","Quality of Life",[174,175,176,177],"Under water exercise","Aerobic exercise","Muscle power","Quality of life","2025-11-22",{"date":180,"type":33},"2025-11-25",{"date":182,"type":22},"2025-12-01",{"date":184,"type":22},"2026-01-20",{"name":39,"class":40},{"id":187,"slug":188,"hasResults":11,"nctId":189,"briefTitle":190,"officialTitle":191,"acronym":4,"eligibilityCriteria":192,"healthyVolunteers":11,"sex":17,"minAge":120,"maxAge":19,"enrollmentInfo":193,"targetDuration":4,"studyType":23,"phases":195,"briefSummary":196,"conditions":197,"keywords":4,"overallStatus":105,"whyStopped":4,"lastUpdateSubmitDate":199,"lastUpdatePostDateStruct":200,"startDateStruct":202,"completionDateStruct":203,"leadSponsor":204,"locationsCount":4},"100611014","passive-fit-and-time-efficiency-in-all-on-x-implants-protocols-using-photogrammetry-splinted-scan-bodies-and-conventional-impression-technique-100611014","NCT07235072","Passive Fit and Time Efficiency in All On-X Implants Protocols Using Photogrammetry, Splinted Scan Bodies, and Conventional Impression Technique","Comparative Analysis of Passive Fit and Time Efficiency in Allon-X Implants Protocols Using Photogrammetry, Splinted Scan Bodies, and Conventional Impression Technique","Inclusion Criteria:\n\nAdults aged 45-65 years.\n\nFully edentulous or partially edentulous maxilla requiring full-arch rehabilitation.\n\nSufficient maxillary bone volume to support at least four implants according to the All-on-X protocol.\n\nSystemically healthy patients with no contraindications to dental implant surgery (ASA I-II classification).\n\nDemonstrated ability to maintain adequate oral hygiene.\n\nWillingness to participate in the study and comply with follow-up visits and required maintenance protocols.\n\nPatients seeking a fixed, implant-supported prosthesis for the maxilla due to missing teeth and inability to use removable prostheses effectively.\n\nAcceptable radiographic findings with no signs of pathology, infection, or significant anatomical limitations.\n\nExclusion Criteria:\n\nUncontrolled systemic diseases (e.g., uncontrolled diabetes, osteoporosis, immunosuppressive disorders)\n\nHistory of radiation therapy to the head and neck region\n\nActive periodontal disease or untreated caries\n\nMaxillary cysts, tumors, or pathologies\n\nPoor oral hygiene or inability to maintain postoperative care\n\nInsufficient bone volume for All-on-X without extensive grafting\n\nMaxillary sinus pathology or oroantral fistula\n\nPsychiatric illness or cognitive impairment affecting compliance\n\nBruxism or parafunctional habits\n\nPregnant or lactating women\n\nHistory of implant failure or titanium allergy\n\nUse of bisphosphonates or antiresorptive medications\n\nHeavy smoking (\\>10 cigarettes\u002Fday)\n\nInability or unwillingness to attend follow-up visits\n\nDiagnosed or symptomatic temporomandibular joint disorders (pain, clicking, locking, limited opening)",{"count":194,"type":22},14,[25],"compare the passive fit of three impression techniques: photogrammetry, intraoral digital scanning with splinted scan bodies, and the conventional open-tray impression technique, within the context of the All-on-X treatment concept. This comparison is expected to provide valuable clinical evidence to support clinicians in making informed decisions when considering the adoption of digital alternatives to conventional methods.",[198],"Passive Fit of Full-arch Implant Prostheses","2025-11-19",{"date":201,"type":33},"2025-11-24",{"date":61,"type":22},{"date":111,"type":22},{"name":39,"class":40},{"id":206,"slug":207,"hasResults":11,"nctId":208,"briefTitle":209,"officialTitle":209,"acronym":4,"eligibilityCriteria":210,"healthyVolunteers":16,"sex":96,"minAge":18,"maxAge":211,"enrollmentInfo":212,"targetDuration":4,"studyType":23,"phases":214,"briefSummary":215,"conditions":216,"keywords":218,"overallStatus":105,"whyStopped":4,"lastUpdateSubmitDate":220,"lastUpdatePostDateStruct":221,"startDateStruct":223,"completionDateStruct":225,"leadSponsor":226,"locationsCount":41},"100604755","effect-of-wim-hof-breathing-exercise-on-ventilatory-functions-in-smokers-100604755","NCT07153640","EFFECT OF WIM HOF BREATHING EXERCISE ON VENTILATORY FUNCTIONS IN SMOKERS","Inclusion Criteria:\n\n* • The age of the subjects ranged from 18-29 years old.\n\n  * The males are participated.\n  * Any subjects smoking electronic cigarettes (vaping).\n  * Subjects with body mass index between 18.5 - 29.9 Kg\u002Fm2.\n  * Penn State Electronic Cigarette Dependence Index (moderate and high dependent) (Appendix 1) (Maraqa et al., 2024).\n\nExclusion Criteria:\n\n* • History of syncope (fainting).\n\n  * High blood pressure (\\>140\u002F100 mm Hg) (Shandu et al., 2023a).\n  * Any type of heart disease.\n  * Seizures or Epilepsy.\n  * Recent surgery.\n  * Metabolic disorders.\n  * Subjects with body mass index more than 35 Kg\u002Fm2.","29 Years",{"count":213,"type":22},42,[25],"Cigarette smoking is the most common form of tobacco use worldwide, but other tobacco products, such as e-cigarettes, cigars, cigarillos, roll-your-own, pipes, and various smokeless tobacco products are also damaging. Most harmful chemicals in cigarette smoke target metals or carbonyls generated by the thermal decomposition of carrier liquids such as propylene glycol, which is one of the main ingredients in the liquid used in electronic cigarettes, where it serves as both the carrier for nicotine and cannabinoids and the means of producing vapor which resemble smoke. This new tobacco product was made of milder sorts of tobacco, the smoke could be inhaled, and it was more damaging.",[217],"Smoking Electronic Cigarettes (Vaping), With Moderate and High Dependence for Nicotine",[219],"WIM HOF BREATHING EXERCISE","2025-08-30",{"date":222,"type":33},"2025-09-04",{"date":224,"type":22},"2025-09-01",{"date":35,"type":22},{"name":39,"class":40},{"id":228,"slug":229,"hasResults":11,"nctId":230,"briefTitle":231,"officialTitle":231,"acronym":4,"eligibilityCriteria":232,"healthyVolunteers":11,"sex":17,"minAge":72,"maxAge":233,"enrollmentInfo":234,"targetDuration":4,"studyType":23,"phases":235,"briefSummary":236,"conditions":237,"keywords":4,"overallStatus":105,"whyStopped":4,"lastUpdateSubmitDate":239,"lastUpdatePostDateStruct":240,"startDateStruct":242,"completionDateStruct":243,"leadSponsor":245,"locationsCount":41},"100603799","effect-of-virtual-reality-on-pulmonary-function-and-anxiety-levels-in-asthmatic-patients-100603799","NCT07141212","Effect Of Virtual Reality On Pulmonary Function And Anxiety Levels In Asthmatic Patients","Inclusion Criteria:\n\n* Both sexes would be previously diagnosed as bronchial asthma with a cut-off score FEV1: Between 60% and 80% of predicted value or less than 60% of predicted value and FEV1\u002FFVC ratio: May be significantly reduced from normal value 0.75-0.80.\n* The age of the patients will be ranged between 30 and 40 years old.\n* Asthma Control Test(ACT) will be less than 16 can be successfully used to identify those who will be uncontrolled asthma.\n* All patients will be assessed by Hospital Anxiety and Depression Scale (HADS) ;A cut-off score of 11-15 a moderate depression\u002Fanxiety level.\n* Patients who are conscious and cooperative.\n* Patients who are able to understand and follow instruction.\n\nExclusion Criteria:\n\n* Previous participation in any pulmonary rehabilitation program.\n* Cardiovascular instabilities such as: Uncontrolled hypertension, Uncontrolled arrhythmia and Recent ischemic event.\n* Mental disorders preventing protocol implementation.\n* Other chronic respiratory diseases.\n* Pregnant women.\n* New or current smoker.\n* Respiratory tract infection.","40 Years",{"count":50,"type":22},[25],"The Purpose of the Study This study will be conducted to determine the effect of virtual reality on pulmonary function and anxiety levels in moderate to severe asthmatic patients.",[238],"Asthma","2025-08-18",{"date":241,"type":33},"2025-08-26",{"date":220,"type":22},{"date":244,"type":22},"2026-03",{"name":39,"class":40},{"id":247,"slug":248,"hasResults":11,"nctId":249,"briefTitle":250,"officialTitle":251,"acronym":4,"eligibilityCriteria":252,"healthyVolunteers":11,"sex":164,"minAge":18,"maxAge":165,"enrollmentInfo":253,"targetDuration":4,"studyType":23,"phases":254,"briefSummary":256,"conditions":257,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":259,"lastUpdatePostDateStruct":260,"startDateStruct":262,"completionDateStruct":264,"leadSponsor":266,"locationsCount":41},"100527045","phase-2-efficacy-of-vildagliptin-versus-metformin-in-poly-cystic-ovary-syndrome-100527045","NCT06142656","Efficacy of Vildagliptin Versus Metformin in Poly Cystic Ovary Syndrome","Efficacy of Vildagliptin Versus Metformin in Poly Cystic Ovary Syndrome: A Randomized Clinical Trial","Inclusion Criteria:\n\n-Women diagnosed with PCOS according to Rotterdam 2003 criteria National Institute of Health criteria.\n\nExclusion Criteria:\n\n* Patients with history of diabetes mellitus (Type 1 or 2).\n* Patients with liver or renal dysfunction; inflammatory diseases; autoimmune disease; cancer, acute cardiovascular event within last three months\n* Known hypersensitivity or contraindications to use dipeptidyl peptidase-4 (DPP-4) inhibitors\n* Eating disorders (anorexia, bulimia) or gastrointestinal disorders",{"count":21,"type":22},[77,255],"PHASE3","Polycystic ovary syndrome (PCOS) is an endocrine disorder that affects approximately 10-20% of women of reproductive age, Management strategies for PCOS include lifestyle modifications such as diet and physical activity that are the first-line approach to treatment; however, they are reported to be minimally effective in reducing weight or treating PCOS-related symptoms.Pharmacological options are also available; however, they are not explicitly approved for PCOS treatment as they have been primarily used to treat other conditions such as T2DM",[258],"Poly Cystic Ovary Syndrome","2025-07-28",{"date":261,"type":33},"2025-07-30",{"date":263,"type":33},"2023-11-25",{"date":265,"type":22},"2026-02-01",{"name":39,"class":40},{"id":268,"slug":269,"hasResults":11,"nctId":270,"briefTitle":271,"officialTitle":272,"acronym":4,"eligibilityCriteria":273,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":274,"enrollmentInfo":275,"targetDuration":4,"studyType":23,"phases":277,"briefSummary":279,"conditions":280,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":259,"lastUpdatePostDateStruct":282,"startDateStruct":284,"completionDateStruct":286,"leadSponsor":288,"locationsCount":41},"100502347","phase-1-efficacy-of-prednisolone-versus-cerebrolysin-in-the-treatment-of-bells-palsy-100502347","NCT05821075","Efficacy of Prednisolone Versus Cerebrolysin in the Treatment of Bell's Palsy","Comparative Study Between Prednisolone, Cerebrolysin in the Treatment of Bell's Palsy","Inclusion Criteria:\n\n* unilateral acute facial palsy of no identifiable cause\n\nExclusion Criteria:\n\n* Recurrent facial Bell's palsy\n* Pregnancy\n* Diabetes\n* Epilepsy\n* Severe hypertension,\n* Renal or hepatic disease,\n* Gastric or duodenal ulcer\n* presence of acute otitis media or ipsilateral chronic otitis\n* Recent head injury,\n* psychiatric disease\n* If there is any contraindications for corticosteroids","60 Years",{"count":276,"type":22},90,[278,77],"PHASE1","Bell's palsy, a peripheral facial nerve paresis, is the most common disorder of the facial nerve and one of the most common mononeuropathies.\n\nMany patients with Bell's palsy will develop some complications such as synkinesis, crocodile tears and 'sweating' of the ear while eating Commonly used medications to treat Bell's palsy is Corticosteroids Cerebrolysin stimulates the regeneration of the nervous tissue with protective action we aim to study the efficacy of cerebrolycin in Bell's palsy",[281],"Bell Palsy",{"date":283,"type":33},"2025-07-31",{"date":285,"type":33},"2023-08-24",{"date":287,"type":22},"2026-02",{"name":39,"class":40},{"id":290,"slug":291,"hasResults":11,"nctId":292,"briefTitle":293,"officialTitle":294,"acronym":4,"eligibilityCriteria":295,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":274,"enrollmentInfo":296,"targetDuration":4,"studyType":23,"phases":297,"briefSummary":298,"conditions":299,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":259,"lastUpdatePostDateStruct":301,"startDateStruct":302,"completionDateStruct":304,"leadSponsor":306,"locationsCount":307},"100459546","phase-1-fexofenadine-in-patients-with-active-rheumatoid-arthritis-100459546","NCT05264025","Fexofenadine in Patients With Active Rheumatoid Arthritis","Fexofenadine as Adjunct to Standard Rheumatoid Therapy in Patients With Active Rheumatoid","Inclusion Criteria\n\n* Moderate to severe RA (disease activity score-28 joints: DAS-28 \\> 3.2) were recruited.\n* Age between 18 - 60 years having active disease according to the diagnosis of an experienced rheumatologist, being under treatment with disease-modifying anti-rheumatic drugs (DMARDs), not receiving cytokine inhibitors\n* Signing informed consent and willingness of the participant to accept randomization to any assigned treatment arm.\n\nExclusion Criteria:\n\n* History of biological DMARDS.\n* History\u002Fpresence of acute heart disease, liver and kidney diseases, COPD\n* Intolerance or allergy to fexofenadine or methotrexate\n* Alcohol abuse\n* Any changes in using medication (changing the dosage or type of medicines\n* Receive hormone replacement therapy, warfarin, and other anticoagulants",{"count":75,"type":22},[278,77],"Rheumatoid arthritis (RA) is an inflammatory autoimmune polyarthritis affecting ∼1% of the world population, resulting in the loss of joint function and progressive structural damage in affected joints. Fexofenadine has been widely used to treat various allergic diseases, like allergic rhinitis, conjunctivitis and chronic idiopathic urticaria. the molecular mechanisms underlying fexofenadine mediated inhibition of TNF-α signalling",[300],"Rheumatoid Arthritis",{"date":283,"type":33},{"date":303,"type":33},"2022-06-01",{"date":305,"type":22},"2026-01",{"name":39,"class":40},2,{"id":309,"slug":310,"hasResults":11,"nctId":311,"briefTitle":312,"officialTitle":313,"acronym":4,"eligibilityCriteria":314,"healthyVolunteers":11,"sex":17,"minAge":315,"maxAge":165,"enrollmentInfo":316,"targetDuration":4,"studyType":23,"phases":318,"briefSummary":319,"conditions":320,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":322,"lastUpdatePostDateStruct":323,"startDateStruct":325,"completionDateStruct":327,"leadSponsor":329,"locationsCount":41},"100592183","three-dimensional-lumbar-myofascial-release-and-motor-control-in-lumbar-radiculopathy-100592183","NCT06990113","Three-dimensional Lumbar Myofascial Release and Motor Control in Lumbar Radiculopathy","Effect of Three-dimensional Lumbar Myofascial Release With Motor Control Training on Back Perception and Pain in Patients With Lumbar Radiculopathy","Inclusion Criteria:\n\n* Their ages range from 35 to 50 years.\n* Both sex\n* Unilateral lumbar radiculopathy for more than 6 months.\n* Normal body mass index (18.5 - 24.99Kg\u002Fm2).\n\nExclusion Criteria:\n\n* • Any other musculoskeletal disorders of the spine or upper extremity\n\n  * Patients with any other Neurological deficits, psychiatric disease lumbar myelopathy, Cognitive problems, vertebral fractures and previous history of spine or lumbar surgery.\n  * Clinical instability, recent trauma\n  * Structural abnormalities of the spine, osteoporosis, and spasmodic torticollis.\n  * Inflammatory or other specific disorders of spina such as ankylosing spondylitis and rheumatoid arthritis","35 Years",{"count":317,"type":22},32,[25],"to investigate The Efficacy of three-dimensional lumbar myofascial release with motor control training on back perception and pain in lumbar radiculopathy Patients with lumbar radiculopathy demonstrate impairments in function and range of motion to deficits in patient's quality of life.",[321],"Lumbar Radiculopathy","2025-05-18",{"date":324,"type":33},"2025-05-25",{"date":326,"type":33},"2025-04-15",{"date":328,"type":22},"2025-07-15",{"name":39,"class":40},{"id":331,"slug":332,"hasResults":11,"nctId":333,"briefTitle":334,"officialTitle":334,"acronym":335,"eligibilityCriteria":336,"healthyVolunteers":11,"sex":164,"minAge":337,"maxAge":315,"enrollmentInfo":338,"targetDuration":4,"studyType":339,"phases":4,"briefSummary":340,"conditions":341,"keywords":343,"overallStatus":105,"whyStopped":4,"lastUpdateSubmitDate":347,"lastUpdatePostDateStruct":348,"startDateStruct":350,"completionDateStruct":352,"leadSponsor":354,"locationsCount":4},"100570939","impact-of-postural-balance-changes-on-low-back-pain-during-pregnancy-100570939","NCT06713759","Impact of Postural Balance Changes on Low Back Pain During Pregnancy","LBP","Inclusion Criteria:\n\n* Pregnant women in 2nd and 3rd trimesters.\n* Pregnant women suffering from low back pain\n* Their Age will range from 20-35 years.\n* Their Body mass index (BMI) will be less than 35 kg\u002Fm2\n\nExclusion Criteria:\n\n* Non pregnant women.\n* Women who have any history of diseases associated with balance disorder\n* Women who have any Neurological disorders.\n* Women who have Lower limbs deformities\n* Women who have Optical problems and disorders\n* Women who have Cerebrovascular disease","20 Years",{"count":50,"type":22},"OBSERVATIONAL","this study will be conducted to determine the impact of postural balance changes on low back pain during pregnancy",[342,126],"Pregnancy",[344,345,346],"postural balance","low back pain","pregnacy","2024-11-28",{"date":349,"type":33},"2024-12-03",{"date":351,"type":22},"2024-12-05",{"date":353,"type":22},"2025-02-05",{"name":39,"class":40},{"id":356,"slug":357,"hasResults":11,"nctId":358,"briefTitle":359,"officialTitle":360,"acronym":4,"eligibilityCriteria":361,"healthyVolunteers":16,"sex":17,"minAge":362,"maxAge":363,"enrollmentInfo":364,"targetDuration":4,"studyType":23,"phases":366,"briefSummary":368,"conditions":369,"keywords":371,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":373,"lastUpdatePostDateStruct":374,"startDateStruct":376,"completionDateStruct":378,"leadSponsor":380,"locationsCount":41},"100570533","early-phase-1-resin-infiltration-vs-self-assembling-peptide-p11-4-in-treating-white-spot-lesions-100570533","NCT06708481","Resin Infiltration Vs Self-Assembling Peptide (P11-4) in Treating White Spot Lesions","Clinical Outcome of Resin Infiltration Vs Self-Assembling Peptide (P11-4) in Treating White Spot Lesion - a Randomized Clinical Trial","Inclusion Criteria:\n\n* Age (a range from 7-14 years of age was determined)\n* Good general health (absence of disease\u002Fno handicaps, to ensure oral care at home)\n* Preserved pulp vitality of the teeth.\n* Consolidated oral care daily.\n* Agreement by patient and parents (or guardians) to participate in the study\n\nExclusion Criteria:\n\n* Patients with periodontal diseases (periodontal pockets or dental mobility) or radiologically identified pathologies (periapical radiolucency).\n* Teeth revealing any restorations were excluded from the current study.\n* Any previous or planned WSL treatment.","7 Years","14 Years",{"count":365,"type":22},150,[367],"EARLY_PHASE1","Clinical assessment of the effectiveness of two treatment modalities (self-assembling peptide (P11-4) (alone or combined with fluoride) and resin infiltration) for treating white spot lesions",[370],"White Spot Lesion",[372],"Resin Infilteration , white spot lesions , Self assembling peptide, remineralization","2024-11-25",{"date":375,"type":33},"2024-11-27",{"date":377,"type":33},"2024-08-30",{"date":379,"type":22},"2025-02",{"name":39,"class":40},{"id":382,"slug":383,"hasResults":11,"nctId":384,"briefTitle":385,"officialTitle":386,"acronym":4,"eligibilityCriteria":387,"healthyVolunteers":11,"sex":17,"minAge":315,"maxAge":165,"enrollmentInfo":388,"targetDuration":4,"studyType":23,"phases":389,"briefSummary":390,"conditions":391,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":393,"lastUpdatePostDateStruct":394,"startDateStruct":395,"completionDateStruct":397,"leadSponsor":399,"locationsCount":41},"100569520","high-tone-power-therapy-on-neck-pain-and-proprioception-in-cervical-radiculopathy-100569520","NCT06695312","High Tone Power Therapy on Neck Pain and Proprioception in Cervical Radiculopathy","Effect of High Tone Power Therapy on Neck Pain and Proprioception in Cervical Radiculopathy Patients","Inclusion Criteria:\n\n* Their ages range from 35 to 50 years.\n* Both sex\n* With mild to moderate cervical disability according to the neck disability index\n* Unilateral cervical radiculopathy for more than 6 months.\n* Cervical radiculopathy due to disc prolapse (C5-C6) (C6-C7) mild to moderate or disc prolapse according to magnetic resonance image (MRI).\n* Normal body mass index (18.5 - 24.99Kg\u002Fm2).\n\nExclusion Criteria:\n\n* Any other musculoskeletal disorders of the spine or upper extremity\n* Patients with any other Neurological deficits, psychiatric disease Cervical myelopathy, Cognitive problems, vertebral fractures and previous history of spine or cervical surgery.\n* Neck pain with vertigo or with bilateral upper limbs referred pain.\n* Clinical instability, recent trauma and vertebrobasilar insufficiency.\n* Structural abnormalities of the spine, osteoporosis, and spasmodic torticollis.\n* Inflammatory or other specific disorders of spina such as ankylosing spondylitis and rheumatoid arthritis",{"count":213,"type":22},[25],"To investigate the Effect of High Tone Power Therapy on Neck Pain and Proprioception in Cervical Radiculopathy Patients.",[392],"Cervical Radiculopathy","2024-11-24",{"date":375,"type":33},{"date":396,"type":33},"2024-09-15",{"date":398,"type":22},"2024-12-15",{"name":39,"class":40},{"id":401,"slug":402,"hasResults":11,"nctId":403,"briefTitle":404,"officialTitle":405,"acronym":4,"eligibilityCriteria":406,"healthyVolunteers":11,"sex":164,"minAge":18,"maxAge":315,"enrollmentInfo":407,"targetDuration":4,"studyType":23,"phases":408,"briefSummary":409,"conditions":410,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":412,"lastUpdatePostDateStruct":413,"startDateStruct":415,"completionDateStruct":417,"leadSponsor":419,"locationsCount":307},"100566689","effect-of-onion-extract-nanoparticle-gel-phonophoresis-on-postsurgical-scar-of-cesarean-section-100566689","NCT06658444","Effect of Onion Extract Nanoparticle Gel Phonophoresis on Postsurgical Scar of Cesarean Section.","Effect of Onion Extract Nanoparticle Gel Phonophoresis on Postsurgical Scar of Cesarean Section","Inclusion Criteria:\n\nTheir ages will be ≥18 years old. All women had given birth via elective abdominal transversal C-section for the first time.\n\nAll women suffering from Postsurgical Scar Of Cesarean-Section about 2-3 months post-surgery.\n\nAll women will provide an informed consent form agreeing to participate and publication of the study results\n\nExclusion Criteria:\n\nAny pathological conditions or associated injuries affect the result of the study.\n\nSkin disease. Cognitive and psychological impairment. Patients have implanted electronic devices, such as cardiac pacemakers, to prevent ultrasound interference.\n\nWomen with diabetes, cardiovascular problems, or a previous history of any disorder may alter sensation and delay the healing process which counteracts the study's goal.",{"count":50,"type":22},[25],"Cesarean section is one of the most common abdominal operations performed on women. The cesarean section rate is rising rapidly and continuously in many parts of the world. The cesarean-section surgery leaves a scar that requires special care. A horizontal skin incision approximately 10-15 cm long is usually performed during the procedure. Apart from the skin, the following: subcutaneous tissue, fascia, peritoneum, and uterine muscle are cut leaving traces in the form of scars and accompanying ailments, on the one hand, such as pain, tenderness, and hypersensitivity to stimuli, and on the other, limitations, such as contractures or impairment of tissue mobility",[411],"Scar; Previous Cesarean Section","2024-10-24",{"date":414,"type":33},"2024-10-26",{"date":416,"type":33},"2024-09-12",{"date":418,"type":22},"2025-01-01",{"name":39,"class":40},{"id":421,"slug":422,"hasResults":11,"nctId":423,"briefTitle":424,"officialTitle":425,"acronym":426,"eligibilityCriteria":427,"healthyVolunteers":11,"sex":164,"minAge":18,"maxAge":315,"enrollmentInfo":428,"targetDuration":4,"studyType":23,"phases":430,"briefSummary":431,"conditions":432,"keywords":434,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":435,"lastUpdatePostDateStruct":436,"startDateStruct":438,"completionDateStruct":440,"leadSponsor":441,"locationsCount":41},"100560159","high-tone-power-therapy-versus-interferential-current-therapy-in-mothers-with-breastfeeding-related-neck-pain-100560159","NCT06573515","High Tone Power Therapy Versus Interferential Current Therapy in Mothers With Breastfeeding-Related Neck Pain","Effectiveness of High Tone Power Therapy Versus Interferential Current Therapy in Mothers With Breastfeeding-Related Neck Pain","BFRNP","Inclusion Criteria:\n\n* All mothers are medically stable.\n* All mothers are primiparous and currently breastfeed their infants.\n* All mothers will be exclusive breastfeeding mothers.\n* Their ages will be 18-35 years old.\n* Their body mass index will be 18.5 to 24.9 kg\u002Fm2.\n* All mothers will provide an informed consent form agreeing to participate and publication of the study results.\n\nExclusion Criteria:\n\n* Mothers who were pregnant and nursing with known orthopedic and neurological conditions of the spine, upper limbs and shoulder regions prior to breastfeeding.\n* Mothers had cesarean delivery.\n* Mothers with cerebrovascular problems, or any disorder affect the goal of the study.\n* Mothers with preterm babies, low-birth weight babies, intrauterine growth restriction, with chronic diseases like cancer, human immuno-deficiency virus (HIV), tuberculosis and with postpartum complications like postpartum hemorrhage and eclampsia.",{"count":429,"type":22},45,[25],"Breastfeeding is very essential for the growth and development of an infant. World Health Organization recommends exclusive breastfeeding of the baby for the first six months. Duration of breastfeeding ranges from 15-20 minutes and is done after every 2-3 hours. The frequency of breastfeeding is approximately 8-12 times a day. So collectively 5-6 hours in an entire day are spent while feeding the baby. Breastfeeding mothers encounter various musculoskeletal problems. These problems arise due to the inappropriate positions acquired during breastfeeding the baby. Since these positions are maintained for longer durations, they can lead to long-term postural deformities by altering the normal curvature of spine. Moreover hormonal changes of pregnancy may last from 12 weeks postpartum to 6 months postpartum. All these changes will have a long-lasting effect while performing activities of daily living, hampering baby care and self-care (Dandekar et al., 2022). In addition to breast soreness, engorgement, maternal illness, blocked ducts, and mastitis, breastfeeding-related neck pain has a high prevalence among nursing women. It is commonly associated with the adoption of awkward postures during feeding sessions. One of the most common awkward positions adopted by nursing mothers is unsupported head\u002Fneck posture, resulting in sustained neck flexion to monitor the infant during feeding. Such a sustained awkward position with excessive repetition usually puts stress on the neck and back muscles",[433],"Breastfeeding",[433],"2024-08-26",{"date":437,"type":33},"2024-08-27",{"date":439,"type":33},"2024-07-01",{"date":418,"type":22},{"name":39,"class":40},{"id":443,"slug":444,"hasResults":11,"nctId":445,"briefTitle":446,"officialTitle":447,"acronym":4,"eligibilityCriteria":448,"healthyVolunteers":11,"sex":17,"minAge":449,"maxAge":18,"enrollmentInfo":450,"targetDuration":4,"studyType":23,"phases":451,"briefSummary":452,"conditions":453,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":439,"lastUpdatePostDateStruct":455,"startDateStruct":457,"completionDateStruct":458,"leadSponsor":460,"locationsCount":41},"100553892","chitosan-phonophresis-on-cervical-in-smartphone-addicted-users-100553892","NCT06491992","Chitosan Phonophresis on Cervical IN Smartphone Addicted Users","Effect of Chitosan Phonophresis on Cervical Pain and Disability in Smartphone Addicted Users","Inclusion Criteria:\n\n* Their age will be ranged from 16-18 years\n* body mass index will be 26.58 kg\u002Fm2.\n* used a smart phone for more than 1 year for at least 2 hours per day\n* complaining of neck pain after using a smart phone, addiction to smart phone in accordance with the smart phone addiction scale (SAS)\n\nExclusion Criteria:\n\n* any previous head and neck injuries or surgeries\n* any congenital abnormalities or symptomatic deformity in either the cervical or the lumbar spine\n* any uncorrected visual or auditory problems, dizziness, vertigo and headache\n* any systematic diseases, any addiction to alcohol, any additive drugs and sedatives within 48 hours previous to tests\n* body mass index of subjects over25 kg\u002Fm2.","16 Years",{"count":122,"type":22},[25],"A phonophoresis-based drug delivery system is a synchronous approach to improve local drug penetration in neuromuscular diseases associated with neuronal damage, excruciating pain, and local inflammation. Chitosan, a semi-synthetic material, is obtained by partial deacetylation of chitin amines, resulting in copolymers of N-acetylglucosamine and N-glucosamine. Its use has been explored in various biomaterial and medical applications. Chitosan has emerged as a cost-effective, biocompatible, and biodegradable material with many desirable biological properties, improvement of homeostasis and antiviral potential. Chitosan was found to suppress pro-inflammatory cytokines and decreased peripheral nerve edema, the polycationic nature of chitosan allows it to absorb protons, which reduces inflammation and provides an analgesic effect.",[454],"Cervical Pain",{"date":456,"type":33},"2024-07-09",{"date":439,"type":22},{"date":459,"type":22},"2024-10-15",{"name":39,"class":40},""]