[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Oculis\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":82},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,53],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":29,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":42,"lastUpdatePostDateStruct":43,"startDateStruct":46,"completionDateStruct":48,"leadSponsor":50,"locationsCount":5},"100639759","phase-3-privosegtor-investigation-in-optic-neuropathies-efficacy-evaluation-research-100639759",false,"NCT07623668","Privosegtor Investigation in Optic Neuropathies Efficacy Evaluation Research","A Randomized, Double-masked, Placebo-controlled Study Assessing the Efficacy and Safety of Privosegtor (OCS-05) in Patients With Optic Neuritis (ON)","PIONEER-1","Key Inclusion Criteria:\n\n* Adult men and women (aged 18 to 50 years) with the first episode of ON in the study eye, associated with unilateral visual loss.\n* Onset of visual loss symptoms in the previous 12 days before first administration of study treatment.\n\nKey Exclusion Criteria:\n\n\\- Have a history or presence of any disorder or condition that may, in the opinion of the Investigator, likely interfere with the interpretation of the study results or participant safety","ALL","18 Years","50 Years",{"count":21,"type":22},210,"ESTIMATED","INTERVENTIONAL",[25],"PHASE3","The goal of this clinical trial is to evaluate the safety and efficacy of privosegtor, a neuroprotective candidate, in patients diagnosed with optic neuritis (ON).\n\nResearchers will compare privosegtor and the standard of care (methylprednisolone) to a placebo and standard of care (methylprednisolone).",[28],"Optic Neuritis",[28,30,31,32,33,34,35,36,37,38,39,40],"ON","AON","Optic Neuropathy","Multiple Sclerosis","MS","Vision Loss","LCVA","Low Contrast Visual Acuity","Low Contrast Sensitivity","Privosegtor","OCS-05","RECRUITING","2026-06-29",{"date":44,"type":45},"2026-07-01","ACTUAL",{"date":47,"type":45},"2026-05-28",{"date":49,"type":22},"2028-12",{"name":51,"class":52},"Oculis","INDUSTRY",{"id":54,"slug":55,"hasResults":11,"nctId":56,"briefTitle":57,"officialTitle":58,"acronym":59,"eligibilityCriteria":60,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":61,"targetDuration":4,"studyType":23,"phases":63,"briefSummary":65,"conditions":66,"keywords":68,"overallStatus":41,"whyStopped":4,"lastUpdateSubmitDate":73,"lastUpdatePostDateStruct":74,"startDateStruct":76,"completionDateStruct":78,"leadSponsor":80,"locationsCount":81},"100635126","phase-2-a-clinical-study-evaluating-licaminlimab-for-dry-eye-disease-100635126","NCT07548632","A Clinical Study Evaluating Licaminlimab for Dry Eye Disease","A Phase 2b\u002F3, Double-masked, Randomized, Vehicle-controlled, Multicenter Study Evaluating Licaminlimab in Dry Eye Disease Patients With a Specific TNFR1 Genotype","PREDICT-1","Key Inclusion Criteria:\n\n* Physician diagnosis of Dry Eye Disease in the past 6 months\n* Use of over-the-counter tears\n* Must agree to genotype testing\n\nKey Exclusion Criteria:\n\n\\- Have a history or presence of any disorder or condition that may, in the opinion of the Investigator, likely interfere with the interpretation of the study results or participant safety.",{"count":62,"type":22},160,[64,25],"PHASE2","The primary objective of this study is to evaluate the efficacy and safety of the topical ophthalmic administration of licaminlimab as compared to vehicle in participants with Dry Eye Disease and a specific genotype.",[67],"Dry Eye Disease (DED)",[69,70,59,71,72],"licaminlimab","OCS-02","genotype based development","Eye drops","2026-05-27",{"date":75,"type":45},"2026-05-29",{"date":77,"type":45},"2026-04-16",{"date":79,"type":22},"2026-12",{"name":51,"class":52},14,""]