[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Olipop, PBC\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":65},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,42],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100615863","a-study-to-evaluate-the-effects-of-a-prebiotic-soda-on-glycemic-control-in-adults-100615863",false,"NCT07298135","A Study to Evaluate the Effects of a Prebiotic Soda on Glycemic Control in Adults","A Randomized, Open-Label, Controlled Study to Evaluate the Effects of a Prebiotic Soda on Glycemic Control in Adults With Glucose Dysregulation","Inclusion Criteria:\n\n* Able to provide informed consent\n* Willing to comply with all study procedures\n* Male or female, ages 30 - 70 years old\n* Habitual consumers of traditional non-diet soda (average intake 2 - 3 servings (24-36 fl. oz)\u002Fdaily in a typical month, representing usual dietary pattern)\n* BMI between 25 - 35 kg\u002Fm²\n* Fasting plasma glucose between 100 - 125 mg\u002FdL or hemoglobin A1c between 5.7% - 6.4%\n* Low habitual dietary fiber intake, assessed using a qualitative fiber intake screening questionnaire administered at pre-screening\n* Willing to maintain stable tobacco\u002Fnicotine use habits established for ≥ 90 days, with no initiation, cessation, or change in frequency during the study period\n* Willing to maintain stable marijuana, hemp, and CBD product use habits established for ≥ 60 days, with no initiation, cessation, or change in frequency during the study period\n* Willing to maintain habitual diet (with the exception of study products) and physical activity patterns throughout the trial\n\nExclusion Criteria:\n\n* Inability to consume a standard 12 fl. oz. carbonated beverage twice daily\n* Currently engaged or planning to be on an intensive weight loss regimen program\n* Extreme dietary habits in the judgement of the Investigator or has been diagnosed with an eating disorder\n* Habitual use of fiber supplements, inulin-based supplements, acacia fiber, glucomannan, prebiotic supplements, or probiotic supplements within 30 days of study enrollment\n* Known allergy or sensitivity to any of the ingredients in the study products\n* History or presence of uncontrolled and\u002For clinically important medical conditions that could interfere with study results interpretation (i.e., diabetes mellitus, CKD stage 4-5, severe liver disease\u002Fcirrhosis, uncontrolled hypertension, recent myocardial infarction or stroke (within 6 months), severe mental illness or cognitive impairment, immunodeficiency disorders, active infections).\n* Gastrointestinal conditions that could potentially interfere with absorption of the study product (i.e., IBD, celiac disease, short bowel syndrome, chronic pancreatitis, gastroparesis, active peptic ulcer disease, gastric bypass or other bariatric surgeries, severe IBS, chronic diarrhea or malabsorption syndromes, active diverticulitis)\n* Use of oral or injectable steroids within 90 days of enrollment\n* Use of antibiotic therapy within 90 days of enrollment\n* Unstable use of prescription medications within 90 days of enrollment that affect plasma glucose levels (e.g., corticosteroids, thiazide diuretics, beta-blockers (some types), antipsychotics, tacrolimus, protease inhibitors, ACE inhibitors)\n* Use of any of the following prescription medications within 90 days of enrollment: Metformin, sulfonylureas, GLP-1 agonists, SGLT-2 inhibitors, insulin.\n* History or presence of cancer, except non-melanoma skin cancer, within 2 years of enrollment\n* Exposure to any non-registered drug product or participation in another intervention study within 30 days prior to enrollment\n* Recent history (within 12 months) of alcohol or substance abuse\n* History of major trauma or surgical event within 60 days of enrollment\n* Person who is pregnant, planning pregnancy, or lactating\n* Any condition the Investigator believes would interfere with study participation or compliance\n* Consumption of more than 5 prebiotic sodas within the last 30 days prior to enrollment\n* Heavy smoker as defined as smoking 20 or more cigarettes per day, or smoked roughly 1 pack a day for 20+ years (more than 20 pack years)",true,"ALL","30 Years","70 Years",{"count":21,"type":22},224,"ESTIMATED","INTERVENTIONAL",[25],"NA","The main objective of this study is to evaluate the chronic effects of replacing traditional non-diet soda with a prebiotic soda on biomarkers associated with glycemic control in adults with glucose dysregulation who are habitual consumers of traditional soda.",[28],"Blood Glucose Control","RECRUITING","2026-06-29",{"date":32,"type":33},"2026-07-01","ACTUAL",{"date":35,"type":33},"2025-12-17",{"date":37,"type":22},"2026-12",{"name":39,"class":40},"Olipop, PBC","INDUSTRY",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":4,"eligibilityCriteria":48,"healthyVolunteers":16,"sex":17,"minAge":49,"maxAge":50,"enrollmentInfo":51,"targetDuration":4,"studyType":23,"phases":53,"briefSummary":54,"conditions":55,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":57,"lastUpdatePostDateStruct":58,"startDateStruct":60,"completionDateStruct":62,"leadSponsor":64,"locationsCount":41},"100620818","effect-of-prebiotic-sodas-on-postprandial-levels-of-glp-1-pyy-transit-time-and-satiety-levels-a-pilot-study-100620818","NCT07362563","Effect of Prebiotic Sodas on Postprandial Levels of GLP-1, PYY, Transit Time and Satiety Levels: A Pilot Study","Effect of 3 Different Prebiotic Sodas on Postprandial Levels of GLP-1, PYY, Transit Time and Satiety Levels: An Acute, Randomized Controlled Pilot Study in Healthy Participants","Inclusion Criteria:\n\n* Adults aged 18-60 years, inclusive.\n* BMI between 18.0 and 30.0 kg\u002Fm2.\n* Stable weight in the last 3 months (+\u002F-5kg).\n* Willing to abstain from unusual strenuous exercise, consuming alcoholic drinks and from taking fiber supplements for 24 hours before study days.\n* Willing to refrain from smoking tobacco or e-cigarettes, and using marijuana in any form for 12h before and during study visits.\n* Understanding the study procedures and willing to provide informed consent to participate in the study and authorization to release relevant protected health information to the study investigator.\n* Subjects must be eligible to receive income in Canada and be covered by a health insurance plan such as Ontario Health Insurance Plan (OHIP).\n\nExclusion Criteria:\n\n* Self-reported pregnant or breastfeeding women.\n* Subjects with a history of severe food allergies or an allergy to acetaminophen.\n* Known history of diabetes, any gastrointestinal disorder that alters the absorption of nutrients, liver disease, or the presence of any health condition, illness or drug use that increases risk to the subject or to others or may affect the results, as judged by the Qualified Investigator (QI).\n* Subjects who are currently or in the last 2 months have been on oral or injectable GLP-1 receptor agonist (RA) medications.\n* Subjects who consume more than 14 alcoholic drinks per week, or more than 5 alcoholic drinks on any one occasion.\n* Subjects who have been on antibiotic therapy in the last 2 months.\n* Subjects taking the blood thinning drug warfarin.\n* Subjects who are habitual users of the following supplements in the past 30 days: berberine, curcumin, cinnamon, resveratrol, and gardenia.\n* Subjects which have undergone major surgery in the last 3 months.\n* Unwillingness or inability to comply with experimental procedures and to follow Inquis safety guidelines.\n* Subject is currently participating or recently (within 30 days of screening) participated in a clinical trial involving long-term exposure (greater than 24 hours) to an investigational drug, nutritional supplement, or lifestyle modification.","18 Years","60 Years",{"count":52,"type":22},15,[25],"The main objective of this study is to evaluate the acute effects of prebiotic sodas on postprandial levels of glucagon-like peptide-1 (GLP-1), peptide YY (PYY), gastric emptying, and satiety levels in healthy adults.",[56],"Satiety in Healthy Volunteers","2026-01-26",{"date":59,"type":33},"2026-01-28",{"date":61,"type":22},"2026-01",{"date":63,"type":22},"2026-05",{"name":39,"class":40},""]