[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Oregon Research Institute\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":147},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,5,0,[8,40,66,89,117],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":39},"100450199","icbt-internet-based-cognitive-behavioral-therapy-for-maternal-depression-community-implementation-in-head-start-100450199",false,"NCT05142384","ICBT (Internet Based Cognitive Behavioral Therapy) for Maternal Depression: Community Implementation in Head Start","ICBT for Maternal Depression: Community Implementation in Head Start","Inclusion Criteria: Mothers\n\n* Elevated symptoms of depression (i.e., Patient Health Questionnaire or Edinburgh Postnatal Depression Scale score at or above 10)\n* Have a child 2-5 years enrolled in a participating Head Start; be able to communicate in English or Spanish.\n\nInclusion Criteria: Child\n\n\\- 2-5 years of age and enrolled in participation Head Start\n\nExclusion Criteria: Mothers\n\n* Evidence of psychosis or other major mental illness or cognitive disability (observed during recruitment or by HS report) that would interfere with meaningful participation\n* Endorsed score of 3 on final item of the PHQ9 or EPDS indicating frequent thoughts of suicide. Could be enrolled at later date if elevated risk ameliorates\n\nExclusion Criteria: Children\n\n* No exclusion criteria","ALL","2 Years",{"count":19,"type":20},960,"ESTIMATED","INTERVENTIONAL",[23],"NA","Low income women of childbearing age are at increased risk for depression and often do not receive needed treatment. Investigators developed Mom-Net, an on-line cognitive behavioral treatment (CBT) for depression to address the needs of low income women of childbearing age. The intervention program also includes live coaching to help the mothers engage and learn the CBT material. Mom-Net has been shown to be highly effective in reducing depressive symptoms and improving parenting behavior and child adjustment, in earlier controlled trials. In this project the investigators are examining whether access to Mom-Net can be expanded by delivering it in Head Starts (HS).\n\nTo address that broad question, the investigators will focus on two sets of scientific questions:\n\n1. Implementation Questions: e.g., Can HS agencies deliver the program successfully; do HSs choose to sustain the program after the research project ends; what agency characteristics are associated with successful delivery of Mom-Net);\n2. Effectiveness Questions: e.g., Does Mom-Net reduce maternal depression when delivered by Head Start agencies, with HS staff doing the coaching?\n\nHead Start agencies will be randomized to deliver either Mom-Net with the usual high-intensity coaching or with a low-intensity coaching alternative. Within each agency, depressed mothers will be randomized to receive either: 1) Mom-Net program; or 2) Treatment as Usual (TAU;) referral to community mental health providers). Mothers initially assigned to the TAU condition, will have the option of receiving Mom-Net at a later date. Mothers will participate in assessments of depressive symptoms, parenting behavior, and child adjustment at Time 1 (T1; prior to randomization); and Time 2 (T2; after the intervention period) and Time 3 (T3; one year after T1).",[26],"Depression","RECRUITING","2026-03-19",{"date":30,"type":31},"2026-03-23","ACTUAL",{"date":33,"type":31},"2022-12-01",{"date":35,"type":20},"2027-03-31",{"name":37,"class":38},"Oregon Research Institute","OTHER",1,{"id":41,"slug":42,"hasResults":11,"nctId":43,"briefTitle":44,"officialTitle":44,"acronym":4,"eligibilityCriteria":45,"healthyVolunteers":11,"sex":16,"minAge":46,"maxAge":47,"enrollmentInfo":48,"targetDuration":4,"studyType":21,"phases":50,"briefSummary":51,"conditions":52,"keywords":56,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":60,"startDateStruct":62,"completionDateStruct":64,"leadSponsor":65,"locationsCount":39},"100472893","biobehavioral-reward-responses-associated-with-consumption-of-nutritionally-diverse-ultra-processed-foods-100472893","NCT05437809","Biobehavioral Reward Responses Associated With Consumption of Nutritionally Diverse Ultra-Processed Foods","Inclusion Criteria Men and women Age 18-65 years BMI ≥ 30 kg\u002Fm2 Endorse liking the foods included in the compulsory test snacks at a 6 on a scale from 1-10 No history of severe psychiatric illness; current mild to moderate severity of depression, anxiety, or binge eating disorder, determined by the behavioral evaluation and the screening measures will be included Live in the greater Springfield, Oregon area and are willing\u002Fable to participate in six in-person assessments Can access and are willing\u002Fable to use a smartphone\n\nExclusion Criteria Medical condition that may limit consumption of compulsory test snack foods or impact metabolic responses to food consumption Type I or II diabetes (HbA1c \\> 6.5 based on blood test) Uncontrolled hypertension (blood pressure ≥ 140\u002F90 mm Hg) Cardiovascular event (e.g., stroke, myocardial infarction) in the last 12 months Individuals with dietary allergies of aversions to the test snack foods Individuals taking medications that may influence the metabolic responses of interest (e.g., metformin) Individuals who are actively pursuing weight loss or have lost ≥ 5% of their initial weight in the last 6 months Severe symptoms of mood, anxiety, and any severity of thought disorders Severe binge eating disorder or full criteria bulimia Persons with active substance-use disorders Current, active suicidal ideation, and\u002For a suicide attempt within the past year History of bariatric surgery Women who are nursing, pregnant, or planning to become pregnant in the next three months Self-report current diagnosis of a transferrable blood condition (including HIV, hepatitis B, hepatitis C, or syphilis) Self-report prior history of being dizzy or anxious during blood draws and\u002For technician not being able to find a vein.","18 Years","65 Years",{"count":49,"type":20},50,[23],"The changing food environment, with increasingly abundant ultra-processed food (UPF) options, may directly contribute to rising rates of obesity, though it is unknown which ingredients in UPF elevate their reinforcing nature in a way that may lead to overconsumption. The proposed study is the first to systematically examine differences in the rewarding characteristics of and physiological and metabolic responses to UPFs that are high in fat, refined carbohydrates (like sugar), or both. Understanding the biobehavioral underpinnings that enhance the reinforcing potential of ingredients in UPF (e.g., fat vs. refined carbohydrates) can inform novel intervention targets for the treatment of overeating and obesity.",[53,54,55],"Obesity","Overeating","Food Addiction",[57,58],"Ultra-processed foods","Food reward","2026-02-09",{"date":61,"type":31},"2026-02-12",{"date":63,"type":31},"2023-02-20",{"date":35,"type":20},{"name":37,"class":38},{"id":67,"slug":68,"hasResults":11,"nctId":69,"briefTitle":70,"officialTitle":71,"acronym":4,"eligibilityCriteria":72,"healthyVolunteers":73,"sex":16,"minAge":47,"maxAge":74,"enrollmentInfo":75,"targetDuration":4,"studyType":21,"phases":77,"briefSummary":78,"conditions":79,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":81,"lastUpdatePostDateStruct":82,"startDateStruct":84,"completionDateStruct":86,"leadSponsor":88,"locationsCount":39},"100502454","virtual-tai-ji-quan-exercise-to-prevent-falls-in-older-adults-100502454","NCT05822466","Virtual Tai ji Quan Exercise to Prevent Falls in Older Adults","A Remotely Delivered Tai Ji Quan Intervention to Reduce Incidence of Falls in High Risk Community-Dwelling Older Adults","Inclusion Criteria:\n\n* age between 65 and 90 years and\n* having had 1 or more falls in the preceding 12 months or having a score ≥12 seconds on the Timed Up\\&Go (TUG) test.\n\nExclusion Criteria:\n\n* showing a diagnosis of dementia or significant cognitive impairment, as indicated by a score of \\\u003C24 on the Mini Mental State Evaluation (MMSE, range: 0-30);\n* being unable to ambulate independently for household distances; (c) having no medical clearance;\n* having participated in any regular and structured tai ji quan-based or multicomponent exercise programs (≥2 times weekly) in the preceding 6 months;\n* having any physical condition that would preclude participation in moderate-intensity exercise; and\n* being unwilling to commit to the duration of the intervention or accept group assignment.",true,"90 Years",{"count":76,"type":20},620,[23],"To examine two different exercise programs in reducing incidence of falls among community-dwelling older adults",[80],"Accidental Fall","2026-01-30",{"date":83,"type":31},"2026-02-03",{"date":85,"type":31},"2023-09-29",{"date":87,"type":20},"2029-03-31",{"name":37,"class":38},{"id":90,"slug":91,"hasResults":11,"nctId":92,"briefTitle":93,"officialTitle":94,"acronym":4,"eligibilityCriteria":95,"healthyVolunteers":73,"sex":16,"minAge":47,"maxAge":96,"enrollmentInfo":97,"targetDuration":4,"studyType":21,"phases":99,"briefSummary":100,"conditions":101,"keywords":105,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":109,"lastUpdatePostDateStruct":110,"startDateStruct":112,"completionDateStruct":114,"leadSponsor":116,"locationsCount":39},"100495014","a-study-of-dual-task-exercise-training-to-prevent-falls-among-older-adults-with-mild-cognitive-impairment-100495014","NCT05725668","A Study of Dual-task Exercise Training to Prevent Falls Among Older Adults With Mild Cognitive Impairment","Dual-Task Training Exercise to Reduce Falls in Older Adults With Mild Cognitive Impairment","Inclusion Criteria:\n\n* being 65 years and older\n* having complaint of memory loss\n* scoring ≤0.5 on Clinical Dementia Scale\n* having had 1 or more falls in the preceding 12 months or scoring ≥12 seconds on the Timed Up and Go test\n\nExclusion Criteria:\n\n* scoring \\\u003C24 on the Mini-Mental State Examination\n* being able to ambulate independently for household distances\n* having medical clearance\n* having participated in any regular and structured tai ji quan-based exercise programs (≥2 times weekly) in the preceding 6 months\n* having a progressive neuromuscular disorder such as Parkinson's disease or multiple sclerosis\n* being unwilling to be randomized","95 Years",{"count":98,"type":20},336,[23],"To determine the efficacy of a dual-task tai ji quan training therapy in reducing the incidence of falls in older adults with mild cognitive impairment.",[102,103,104],"Mild Cognitive Impairment","Accidental Falls","Aging",[106,107,108],"Falls","Exercise","Dual tasking","2025-12-09",{"date":111,"type":31},"2025-12-17",{"date":113,"type":31},"2023-07-15",{"date":115,"type":20},"2028-01-31",{"name":37,"class":38},{"id":118,"slug":119,"hasResults":11,"nctId":120,"briefTitle":121,"officialTitle":122,"acronym":123,"eligibilityCriteria":124,"healthyVolunteers":11,"sex":16,"minAge":46,"maxAge":125,"enrollmentInfo":126,"targetDuration":4,"studyType":21,"phases":128,"briefSummary":130,"conditions":131,"keywords":134,"overallStatus":138,"whyStopped":4,"lastUpdateSubmitDate":139,"lastUpdatePostDateStruct":140,"startDateStruct":142,"completionDateStruct":144,"leadSponsor":146,"locationsCount":4},"100610342","phase-2-dietary-interventions-to-reduce-ultra-processed-food-intake-100610342","NCT07226336","Dietary Interventions to Reduce Ultra-Processed Food Intake","Testing a Dissonance-Based Intervention to Reduce Ultra-Processed Food Consumption Via Activism Against the Food Industry","DISRUPT","Inclusion Criteria:\n\n* Ages 18-70 years old\n* BMI \\>25 and \\\u003C50 kg\u002Fm2\n* Wish to reduce their UPF intake\n* Consume at least 2 UPF items per day and at least 4 distinct UPF items per week\n\nExclusion Criteria:\n\n* Have ever been diagnosed with anorexia nervosa or bulimia nervosa\n* Are using medications known to influence eating behavior and\u002For weight (e.g., semaglutide)\n* Currently using insulin\n* History of bariatric surgery\n* Current pregnancy or planning to become pregnant during the study period","70 Years",{"count":127,"type":20},60,[129],"PHASE2","The DISRUPT clinical trial will test two different 2-month programs to help adults with overweight\u002Fobesity (N=60) reduce their intake of ultra-processed foods (UPFs). Participants will be randomly assigned to receive standard dietary change strategies, cognitive dissonance strategies that engage them in activism against the UPF industry, or both. All participants will attend an introductory educational workshop about UPFs. If they are assigned to receive one or more of these strategies, they will attend weekly group sessions with the relevant intervention content for 7 more weeks. Groups will be held virtually.",[132,133],"Ultra-Processed Food Intake","Obesity & Overweight",[135,136,137],"Ultra-Processed Food","Dietary Change","Cognitive Dissonance","NOT_YET_RECRUITING","2025-11-05",{"date":141,"type":31},"2025-11-10",{"date":143,"type":20},"2026-02",{"date":145,"type":20},"2026-08",{"name":37,"class":38},""]