[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Otto Helve\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":71},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,47],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":17,"sex":18,"minAge":19,"maxAge":20,"enrollmentInfo":21,"targetDuration":4,"studyType":24,"phases":25,"briefSummary":27,"conditions":28,"keywords":31,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":36,"startDateStruct":39,"completionDateStruct":41,"leadSponsor":43,"locationsCount":46},"100535329","autoflor--lyophilized-capsulated-autological-fmt-to-restore-gut-microbiome-after-treatment-with-antibiotics-100535329",false,"NCT06250413","Autoflor -Lyophilized Capsulated Autological FMT to Restore Gut Microbiome After Treatment With Antibiotics","Lyophilized Capsulated Autological Fecal Microbial Transplant to Restore Gut Microbiome After Treatment With Antibiotics","FMT","Inclusion Criteria:\n\n-previously healthy\n\nExclusion Criteria:\n\n* IBD (inflammatory bowel disease)\n* celiac disease\n* abdominal symptoms such as diarrhea or constipation necessitating medical therapy\n* pregnancy and breastfeeding\n* allergy towards antibiotics penicillins\n* allergy towards soya.\n* trehalose intolerance.\n* travelling outside of European Union during the last 3 months\n* use of antibiotics during the last 3 months\n* use of probiotics during the previous 2 weeks or during the study.",true,"ALL","18 Years","40 Years",{"count":22,"type":23},40,"ESTIMATED","INTERVENTIONAL",[26],"NA","In this clinical trial, our aim is to assess the effect of auto-FMT (Fecal microbiome transplantation) on the intestinal microbiota, after a course of antibiotics.\n\n30 healthy adults are recruited. All are given a five day course of amoxicillin-clavulanate. The subjects are double blinded and randomized to two groups. Group A is given autologous FMT (auto-FMT) on day 7 (two days after the end of the course of antibiotics) and Group B is given auto-FMT on day 28 (23 days after the end of the course of antibiotics).",[29,30],"Microbial Colonization","Antibiotic Side Effect",[15,32,33],"lyophilized","antibiotics","NOT_YET_RECRUITING","2024-02-13",{"date":37,"type":38},"2024-02-14","ACTUAL",{"date":40,"type":23},"2024-02",{"date":42,"type":23},"2027-12",{"name":44,"class":45},"Otto Helve","OTHER",1,{"id":48,"slug":49,"hasResults":11,"nctId":50,"briefTitle":51,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":54,"minAge":19,"maxAge":4,"enrollmentInfo":55,"targetDuration":4,"studyType":24,"phases":57,"briefSummary":58,"conditions":59,"keywords":60,"overallStatus":34,"whyStopped":4,"lastUpdateSubmitDate":35,"lastUpdatePostDateStruct":65,"startDateStruct":67,"completionDateStruct":68,"leadSponsor":70,"locationsCount":46},"100533594","preterm-infant-intestinal-microbiota-development-and-maternal-fecal-transplant-100533594","NCT06227845","Preterm Infant Intestinal Microbiota Development and Maternal Fecal Transplant","PREFLOR","Inclusion Criteria:\n\n* Pregnant women with preeclampsia or other risk factors of preterm labor (eg cervix insufficiency or placenta previa) between 29+0 - 34+0 weeks of pregnancy.\n* Either parent fluent in Finnish.\n\nExclusion Criteria:\n\n* Women with other significant medical conditions including acute infection, IBD, celiac disease.\n* Travelling outside the EU and use of antibiotics during the last 3 months.\n* Gestational diabetes with insulin medication.\n* Pregnant with multiples.","FEMALE",{"count":56,"type":23},36,[26],"The goal of this clinical trial is to study if a oral maternal fecal transplant given to a premature infant born by cesarean section (CS) is safe. The investigators will also compare the gut microbiome of the infants to those born by CS and not received the transplant and to premature infants born vaginally.",[29],[61,62,63,64],"Premature infant","Fecal microbiota transplant","Cesarean section","Immune system development",{"date":66,"type":38},"2024-02-15",{"date":40,"type":23},{"date":69,"type":23},"2026-12",{"name":44,"class":45},""]