[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Pak Emirates Military Hospital\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":231},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,9,0,[8,42,71,98,122,148,166,191,212],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":17,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100645031","phase-4-comparison-of-itraconazole-with-itraconazole-and-isotretinoin-in-the-treatment-duration-safety-a-n-d-cure-rate-in-adult-patients-of-tinea-corporis-cruris-a-randomised-controlled-trail-100645031",false,"NCT07675239","Comparison of Itraconazole With Itraconazole and Isotretinoin in the Treatment Duration, Safety a n d Cure Rate in Adult Patients of Tinea Corporis\u002F Cruris-A Randomised Controlled Trail","Comparison of Itraconazole With Itraconazole and Isotretinoin in the Treatment Duration, Safety, and Cure Rate in Adult Patients With Tinea Corporis\u002FCruris: A Randomized Controlled Trial.","Inclusion Criteria:\n\n* Al newly diagnosed cases with typical tinea lesion involving at least 5% body surface area (BSA) with no nail\u002Fscalp\u002Fpalm\u002Fsole involvement and no history of intake of any oral antifungal in the preceding 4 weeks or of a topical antifungal\u002Fsteroid in the preceding 2 weeks. Presenting to the outpatient department or the emergency department of PEMH or CMH will be included in the study.\n\nExclusion Criteria:\n\n* 1\\. Patients with chronic liver and renal diseases. 2. Patients with ischaemic heart diseases. 3. Patients with hyperlipidemia. 4. 5. Those on chronic immunosuppressive therapy. Pregnant and lactating women and females of reproductive age. 6. Elderly patients above 75 years 7. Patient who had taken oral antifungal in the preceding 4 weeks or of a topical antifungal\u002Fsteroid in the preceding 2 weeks","ALL","75 Years",{"count":19,"type":20},60,"ESTIMATED","INTERVENTIONAL",[23],"PHASE4","Tinea corporis and tinea cruris are common superficial fungal infections that have become increasingly difficult to treat because of prolonged disease duration, frequent recurrences, and suboptimal response to standard antifungal therapy. Itraconazole is widely used for the treatment of dermatophytosis; however, treatment failures and relapses remain a significant concern. Isotretinoin has been proposed as an adjuvant therapy because of its effects on epidermal differentiation, keratinization, and follicular function, which may enhance antifungal penetration and improve treatment outcomes.\n\nThis randomized controlled trial aims to compare itraconazole monotherapy with a combination of itraconazole and isotretinoin in adult patients with tinea corporis and\u002For tinea cruris. The study will evaluate treatment duration, cure rate, and safety profile of both regimens. The findings may provide evidence regarding the potential benefit of adding isotretinoin to conventional antifungal therapy and help optimize management strategies for adult patients with dermatophytosis.",[26],"Tinea Corporis",[28],"Tinea, itraconazol, isotretinoin","NOT_YET_RECRUITING","2026-06-23",{"date":32,"type":33},"2026-06-30","ACTUAL",{"date":35,"type":20},"2026-10-01",{"date":37,"type":20},"2027-03-01",{"name":39,"class":40},"Pak Emirates Military Hospital","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":47,"acronym":48,"eligibilityCriteria":49,"healthyVolunteers":11,"sex":16,"minAge":50,"maxAge":51,"enrollmentInfo":52,"targetDuration":4,"studyType":21,"phases":54,"briefSummary":55,"conditions":56,"keywords":58,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":4},"100639640","phase-4-dexamethasone-plus-metoclopramide-versus-paracetamolnsaids-for-primary-headache-100639640","NCT07605065","Dexamethasone Plus Metoclopramide Versus Paracetamol\u002FNSAIDs for Primary Headache","Comparison of Efficacy of Combination Dexamethasone With Metoclopramide Versus Paracetamol\u002FNSAIDs for Treatment of Primary Headache in ED at Tertiary Care Hospital: A Randomized Controlled Trial","DMPH","Inclusion Criteria:\n\n* Patients aged 18 to 60 years.\n* Patients presenting with primary headache diagnosed clinically.\n* Patients presenting within 72 hours of onset of headache.\n* Patients with Visual Analogue Scale (VAS) pain score ≥5.\n\nExclusion Criteria:\n\n* Patients with secondary headache disorders.\n* Patients with known allergy to dexamethasone, metoclopramide, paracetamol, or NSAIDs.\n* Pregnant females.\n* Patients with hepatic impairment.\n* Patients with renal impairment.\n* Patients with peptic ulcer disease or gastrointestinal bleeding.\n* Patients with extrapyramidal disorders.\n* Patients already receiving corticosteroids within previous 48 hours.","18 Years","60 Years",{"count":53,"type":20},94,[23],"Primary headache disorders are among the most common neurological conditions presenting to emergency departments and can significantly impair quality of life and daily functioning. Various medications are used for acute headache treatment, including paracetamol, non-steroidal anti-inflammatory drugs (NSAIDs), metoclopramide, and corticosteroids.\n\nThis randomized controlled trial aims to compare the efficacy of intravenous dexamethasone combined with metoclopramide versus intravenous paracetamol\u002FNSAIDs in patients presenting with primary headache to the emergency department of Pak Emirates Military Hospital, Rawalpindi.\n\nA total of 94 patients aged 18 to 60 years with clinically diagnosed primary headache will be enrolled and randomized into two groups. Group A will receive intravenous dexamethasone 8 mg plus intravenous metoclopramide 10 mg, while Group B will receive intravenous paracetamol or NSAIDs according to departmental protocol. Pain severity will be assessed using the Visual Analogue Scale (VAS) before treatment and again after 60 minutes. Treatment efficacy will be defined as at least 50% reduction in pain score from baseline.\n\nThe results of this study may help identify a more effective treatment strategy for acute primary headache management in emergency departments.",[57],"Primary Headache",[59,60,61,62],"Dexamethasone","Metoclopramide","Paracetamol","NSAIDs","2026-05-17",{"date":65,"type":33},"2026-05-22",{"date":67,"type":20},"2026-11-01",{"date":69,"type":20},"2027-11-01",{"name":39,"class":40},{"id":72,"slug":73,"hasResults":11,"nctId":74,"briefTitle":75,"officialTitle":76,"acronym":4,"eligibilityCriteria":77,"healthyVolunteers":11,"sex":16,"minAge":4,"maxAge":4,"enrollmentInfo":78,"targetDuration":4,"studyType":21,"phases":80,"briefSummary":82,"conditions":83,"keywords":85,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":91,"startDateStruct":93,"completionDateStruct":95,"leadSponsor":97,"locationsCount":4},"100639958","effect-of-early-vs-late-water-exposure-after-cutaneous-surgery-100639958","NCT07580274","Effect of Early vs Late Water Exposure After Cutaneous Surgery","Effect of Early vs Late Exposure of Water Post-cutaneous Surgeries : A Randomized Controlled Trial","Inclusion Criteria:\n\n* Patients undergoing elective surgical procedures, such as excision of benign or malignant skin lesions, skin grafts, and skin biopsies.\n\nExclusion Criteria:\n\n* 1.Patients on anti-coagulants.\n\n  2.Compromised immune systems e.g. pregnancy, diabetes, immunosuppressive therapies.\n\n  3.Wounds that are located in areas with significant movements (e.g. joints) or that are highly prone to external contaminants (e.g. mucosal surfaces) which might bias result.",{"count":79,"type":20},82,[81],"NA","This randomized controlled trial aims to compare the effect of early versus delayed water exposure after cutaneous surgeries on the incidence of surgical site infections. Patients undergoing elective cutaneous surgical procedures will be randomly assigned to either early postoperative water exposure within 48 hours or delayed exposure after 7 days. Wound outcomes will be assessed using the Southampton Wound Grading System during follow-up visits. The study seeks to determine whether early water exposure is safe and whether it influences postoperative wound healing and infection rates.",[84],"Surgical Site Infection (SSI)",[86,87,88,89],"Cutaneous surgery","Surgical wound infection","Early water exposure","Post operative wound care","2026-05-06",{"date":92,"type":33},"2026-05-12",{"date":94,"type":20},"2026-06-01",{"date":96,"type":20},"2026-12-01",{"name":39,"class":40},{"id":99,"slug":100,"hasResults":11,"nctId":101,"briefTitle":102,"officialTitle":103,"acronym":4,"eligibilityCriteria":104,"healthyVolunteers":11,"sex":16,"minAge":50,"maxAge":105,"enrollmentInfo":106,"targetDuration":4,"studyType":21,"phases":108,"briefSummary":109,"conditions":110,"keywords":112,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":90,"lastUpdatePostDateStruct":118,"startDateStruct":119,"completionDateStruct":120,"leadSponsor":121,"locationsCount":4},"100637755","comparison-of-methotrexate-and-tofacitinib-in-chronic-plaque-psoriasis-100637755","NCT07581418","Comparison of Methotrexate and Tofacitinib in Chronic Plaque Psoriasis","Comparison of Outcome Between Oral Methotrexate and Tofacitinib in Treatment of Chronic Plaque Psoriasis","Inclusion Criteria:\n\n* Eligible participants will comprise adults aged 18 to 70 years, of either gender, with moderate to severe plaque psoriasis defined by a Psoriasis Area and Severity Index (PASI) score greater than 10. A minimum disease duration of 6 months will be required. In addition, enrolment will be limited to patients whose psoriasis has shown inadequate response to at least one topical therapy despite a treatment duration of at least 4 weeks\n\nExclusion Criteria:\n\n* Participants with non-plaque variants of psoriasis or any other clinically significant dermatological condition that could confound the assessment of psoriasis severity. Recent exposure to anti psoriatic therapy including systemic or biologic treatment within the preceding 4 weeks or topical treatment within the preceding 2 weeks. Individuals with known hypersensitivity to, or contraindications for, either methotrexate or tofacitinib. Patients with a history of significant hepatic, renal, hematologic, gastrointestinal, or immune system disorders. Pregnant or breastfeeding women. Patients unavoidable prolonged sun or ultraviolet exposure. Patients with a history of alcohol abuse, or other conditions that contraindicate methotrexate use..","70 Years",{"count":107,"type":20},88,[81],"This randomized controlled trial aims to compare the efficacy and safety of oral methotrexate and tofacitinib in patients with chronic plaque psoriasis. Participants diagnosed with chronic plaque psoriasis will be randomly assigned to receive either methotrexate or tofacitinib and will be followed for six months. Clinical improvement, disease severity, treatment response, and adverse effects will be assessed and compared between the two treatment groups.",[111],"Chronic Plaque Psoriasis",[113,111,114,115,116,117],"Psoriasis","Methotrexate","Tofacitinib","Randomized Controlled Trial","Systemic Therapy",{"date":92,"type":33},{"date":94,"type":20},{"date":96,"type":20},{"name":39,"class":40},{"id":123,"slug":124,"hasResults":11,"nctId":125,"briefTitle":126,"officialTitle":126,"acronym":4,"eligibilityCriteria":127,"healthyVolunteers":128,"sex":129,"minAge":50,"maxAge":130,"enrollmentInfo":131,"targetDuration":4,"studyType":21,"phases":133,"briefSummary":135,"conditions":136,"keywords":139,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":140,"lastUpdatePostDateStruct":141,"startDateStruct":143,"completionDateStruct":145,"leadSponsor":147,"locationsCount":41},"100635263","phase-2-role-of-intravenous-calcium-to-decrease-blood-loss-during-intrapartum-cesarean-section-100635263","NCT07550413","Role of Intravenous Calcium to Decrease Blood Loss During Intrapartum Cesarean Section","Inclusion Criteria:\n\n* Women aged 18-45 years undergoing intrapartum cesarean section at ≥34 weeks of gestation.\n* Exposure to oxytocin during labor before CS.\n* Singleton pregnancy with no known fetal anomalies.\n\nExclusion Criteria:\n\n* Known bleeding disorders or preoperative coagulation abnormalities\n* Preeclampsia or hypertensive disorders contraindicate calcium use.\n* History of cardiac disease or arrhythmias\n* Placental abnormalities, i.e., placenta previa, accreta\n* Emergency CS with fetal distress or cord prolapse.\n* Known hypersensitivity to calcium chloride.",true,"FEMALE","45 Years",{"count":132,"type":20},182,[134],"PHASE2","To determine the effectiveness of prophylactic intravenous calcium chloride administered after cord clamping in reducing postpartum blood loss during intrapartum cesarean section.",[137,138],"Post Partum Haemorrhage","Cesarean Section Surgery",[116],"2026-04-19",{"date":142,"type":33},"2026-04-24",{"date":144,"type":20},"2026-05",{"date":146,"type":20},"2026-12",{"name":39,"class":40},{"id":149,"slug":150,"hasResults":11,"nctId":151,"briefTitle":152,"officialTitle":152,"acronym":4,"eligibilityCriteria":153,"healthyVolunteers":128,"sex":129,"minAge":50,"maxAge":130,"enrollmentInfo":154,"targetDuration":4,"studyType":21,"phases":156,"briefSummary":157,"conditions":158,"keywords":160,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":140,"lastUpdatePostDateStruct":162,"startDateStruct":163,"completionDateStruct":164,"leadSponsor":165,"locationsCount":4},"100635265","effect-of-world-health-organization-labour-care-guide-on-reducing-cesarean-section-rates-100635265","NCT07550439","Effect of World Health Organization Labour Care Guide On Reducing Cesarean Section Rates","Inclusion Criteria:\n\nAll pregnant women in active phase of labour (\\>5cm cervical dilatation) and gestational age of 37 weeks to 41 completed weeks (as assessed on LMP).\n\nPrevious no caesarean section. Age 18-40 years. Both primiparous and multiparous. Both booked and unbooked.\n\nExclusion Criteria:\n\nWomen with chronic hypertension (BP \\>140\u002F90 mmHg on 2 consecutive occasions). Pregnancy induced Hypertension: women with no history of hypertension (blood pressure \\>140\u002F90 mmHg on 2 consecutive occasions) and diagnosed in pregnancy.\n\nGestational Diabetes mellitus: women with no history of diabetes mellitus (FBS \\>110 mg\u002Fdl on 2 consecutive occasions) and diagnosed in pregnancy.\n\nWomen who had a caesarean section in the latent phase of labour.",{"count":155,"type":20},174,[81],"After taking informed consent for participation in the study, all selected cases will be divided into two groups by lottery method. In group A, patients will receive care using WHO Labour Care Guide while in group B, patients will be monitored using WHO partograph.",[159],"Labour",[161],"Labour Care Guide",{"date":142,"type":33},{"date":144,"type":20},{"date":146,"type":20},{"name":39,"class":40},{"id":167,"slug":168,"hasResults":11,"nctId":169,"briefTitle":170,"officialTitle":170,"acronym":4,"eligibilityCriteria":171,"healthyVolunteers":128,"sex":16,"minAge":172,"maxAge":4,"enrollmentInfo":173,"targetDuration":4,"studyType":21,"phases":175,"briefSummary":177,"conditions":178,"keywords":180,"overallStatus":183,"whyStopped":4,"lastUpdateSubmitDate":184,"lastUpdatePostDateStruct":185,"startDateStruct":187,"completionDateStruct":189,"leadSponsor":190,"locationsCount":41},"100615585","early-phase-1-efficacy-of-platelet-rich-fibrin-gel-in-patients-with-chronic-leg-ulcers-100615585","NCT07294521","Efficacy of Platelet-rich-Fibrin Gel in Patients With Chronic Leg Ulcers","Inclusion Criteria:\n\n* All male and female patients more than 35 years old with Chronic Leg Ulcers, presenting to the OPD will be included.\n\nExclusion Criteria:\n\n* Patients with clinical signs of infected ulcers, patients in sepsis and immunosuppressed individuals will be excluded.","35 Years",{"count":174,"type":20},40,[176],"EARLY_PHASE1","Platelet rich Fibrin (PRF) gel is an emerging as a novel treatment option for chronic leg ulcers and has the potential to become the 1st line option in these conditions. The objective of our study will be to assess the efficacy of PRF gel dressing in patients with non-infective chronic leg ulcers.",[179],"Chronic Leg Ulcer",[181,182],"Chronic leg ulcer","Platelet rich fibrin","RECRUITING","2026-03-09",{"date":186,"type":33},"2026-03-11",{"date":188,"type":33},"2025-12-16",{"date":92,"type":20},{"name":39,"class":40},{"id":192,"slug":193,"hasResults":11,"nctId":194,"briefTitle":195,"officialTitle":195,"acronym":4,"eligibilityCriteria":196,"healthyVolunteers":128,"sex":16,"minAge":197,"maxAge":51,"enrollmentInfo":198,"targetDuration":4,"studyType":21,"phases":200,"briefSummary":201,"conditions":202,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":204,"lastUpdatePostDateStruct":205,"startDateStruct":207,"completionDateStruct":209,"leadSponsor":211,"locationsCount":41},"100562424","measuring-the-density-of-iodine-in-lipiodol-depositions-detecting-an-invisible-residual-tumor-after-conventional-transarterial-chemoembolization-for-hepatocellular-carcinoma-100562424","NCT06602986","Measuring the Density of Iodine in Lipiodol Depositions: Detecting an Invisible Residual Tumor After Conventional Transarterial Chemoembolization for Hepatocellular Carcinoma","Inclusion Criteria:\n\n* Clinical diagnosis of HCC disease\n* Must be able to swallow tablets\n\nExclusion Criteria:\n\n* Insulin dependent diabetes\n* Thyroid disease","16 Years",{"count":199,"type":20},96,[81],"ABSTRACT Objective: To detect presence of a residual tumor in patients of hepatocellular carcinoma (HCC) treated with Lipiodol based conventional trans arterial chemoembolization (cTACE) using density measurements on follow-up computed tomography (CT) scans Study Design: Prospective observational interventional study Place and Duration of Study: Interventional Radiology department of Armed Forces Institute of Radiology and Imaging (AFIRI) from April 2023-March 2024 Methodology: 96 patients undergoing conventional TACE were included in the study and followed up for residual tumor or tumor free status assessment using density measurement for iodine depositions using CT scan analysis and compared with gold standard digital subtraction angiography (DSA). Primary variables measured were comparison of enhancement scores between those with a residual tumor versus tumor free as well as the volume of iodine depositions in the arterial and venous phase between both groups. Sensitivity and specificity of the CT scan in assessing tumor diagnosis was compared with the gold standard digital subtraction angiography.",[203],"HCC - Hepatocellular Carcinoma","2024-09-17",{"date":206,"type":33},"2024-09-19",{"date":208,"type":20},"2024-10-12",{"date":210,"type":20},"2025-07-13",{"name":39,"class":40},{"id":213,"slug":214,"hasResults":11,"nctId":215,"briefTitle":216,"officialTitle":217,"acronym":4,"eligibilityCriteria":218,"healthyVolunteers":128,"sex":16,"minAge":50,"maxAge":51,"enrollmentInfo":219,"targetDuration":4,"studyType":21,"phases":221,"briefSummary":222,"conditions":223,"keywords":4,"overallStatus":183,"whyStopped":4,"lastUpdateSubmitDate":204,"lastUpdatePostDateStruct":225,"startDateStruct":226,"completionDateStruct":228,"leadSponsor":230,"locationsCount":41},"100541434","incidence-of-regurgitation-in-patients-undergoing-intubation-in-semi-fowler-vs-supine-position-100541434","NCT06329817","Incidence of Regurgitation in Patients Undergoing Intubation in Semi-fowler v\u002Fs Supine Position","Incidence of Regurgitation in Patients Undergoing Intubation in Semi-fowler v\u002Fs Supine Position in a Tertiary Care Hospital","Inclusion Criteria:\n\n* Adults 18-60 years of age\n* Must be able to talk\n\nExclusion Criteria:\n\n* patients less than 18 years of age or above 60,\n* Pregnant women\n* Handicapped individuals\n* patients with intestinal obstruction",{"count":220,"type":20},100,[81],"One of the most dreaded complication of general anaesthesia is aspiration of gastric contents after induction of general anaesthesia.Many endeavours and measures have been practiced to reduce the incidence of aspiration pneumonia.One such method is to intubate the patient in semi-fowler or supine posture.My study is aimed to find out safe and best position between these two after induction of general anaesthesia to prevent aspiration pneumonia.",[224],"Inguinal Hernia Bilateral",{"date":206,"type":33},{"date":227,"type":33},"2024-03-16",{"date":229,"type":20},"2025-09",{"name":39,"class":40},""]