[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Pakistan Air Force (PAF) Hospital Islamabad\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":77},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,49],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":29,"overallStatus":36,"whyStopped":4,"lastUpdateSubmitDate":37,"lastUpdatePostDateStruct":38,"startDateStruct":41,"completionDateStruct":43,"leadSponsor":45,"locationsCount":48},"100641079","daily-versus-alternate-day-oral-iron-therapy-for-anemia-in-second-trimester-pregnancy-100641079",false,"NCT07657455","Daily Versus Alternate-Day Oral Iron Therapy for Anemia in Second-Trimester Pregnancy","Daily Versus Alternate-Day Oral Iron Therapy for Anemia Correction in Second-Trimester Pregnant Patients: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Aged 18 to 40 years\n* Pregnant women in the second trimester (13 to 27 weeks gestation)\n* Hemoglobin below 11 g\u002FdL with serum ferritin below 30 ng\u002FmL\n* Singleton pregnancy\n\nExclusion Criteria:\n\n* Known congenital or acquired hemoglobin disorders (e.g., thalassemia, hemoglobinopathies)\n* Chronic diseases affecting hemoglobin levels (e.g., chronic kidney disease, inflammatory disorders)\n* Bleeding disorders or a history of frequent blood loss\n* Gastrointestinal conditions impairing nutrient absorption (e.g., celiac disease or other malabsorption syndromes)\n* Currently receiving parenteral iron\n* Requiring blood transfusion","FEMALE","18 Years","40 Years",{"count":20,"type":21},184,"ESTIMATED","INTERVENTIONAL",[24],"NA","This randomized controlled trial compares daily versus alternate-day oral iron supplementation in pregnant women with iron deficiency anemia during the second trimester. The study evaluates changes in hemoglobin and serum ferritin, treatment adherence, and gastrointestinal side effects to inform more patient-centered, physiologically aligned dosing strategies.",[27,28],"Iron Deficiency Anemia","Anemia in Pregnancy",[30,31,32,33,34,35],"oral iron","ferrous sulfate","alternate-day dosing","hepcidin","second trimester","adherence","NOT_YET_RECRUITING","2026-06-14",{"date":39,"type":40},"2026-06-18","ACTUAL",{"date":42,"type":21},"2026-09",{"date":44,"type":21},"2027-02",{"name":46,"class":47},"Pakistan Air Force (PAF) Hospital Islamabad","OTHER",1,{"id":50,"slug":51,"hasResults":11,"nctId":52,"briefTitle":53,"officialTitle":53,"acronym":4,"eligibilityCriteria":54,"healthyVolunteers":55,"sex":16,"minAge":17,"maxAge":56,"enrollmentInfo":57,"targetDuration":4,"studyType":59,"phases":4,"briefSummary":60,"conditions":61,"keywords":64,"overallStatus":68,"whyStopped":4,"lastUpdateSubmitDate":69,"lastUpdatePostDateStruct":70,"startDateStruct":72,"completionDateStruct":74,"leadSponsor":76,"locationsCount":48},"100590071","association-of-urinary-tract-infection-with-preeclampsia-during-pregnancy-100590071","NCT06962644","Association of Urinary Tract Infection With Preeclampsia During Pregnancy","Inclusion Criteria:\n\n* Patients attending OPD for routine antenatal checkup\n* Patients diagnosed with UTI as per operational definitions\n* Gestational age greater than 20 weeks as per LMP\n* Age between 18 to 35 years\n\nExclusion Criteria:\n\n* History of medical conditions such as:\n* Diabetes mellitus\n* Chronic hypertension\n* Chronic liver or kidney diseases\n* Chronic pulmonary conditions\n* History of urological surgical interventions in the past 3 months\n* History of renal transplants\n* Patients on immunosuppressive therapy\n* History of comorbid conditions including:\n* Diabetes mellitus\n* Gestational diabetes mellitus\n* Hypertension\n* Chronic hepatic diseases\n* Chronic liver diseases\n* Chronic pulmonary diseases\n* Ischemic heart diseases",true,"35 Years",{"count":58,"type":21},160,"OBSERVATIONAL","Urinary tract infections (UTIs) are a major clinical issue, especially in pregnant women, due to physiological changes that increase susceptibility. If untreated, UTIs can lead to severe complications like preterm labor and low birth weight. Preeclampsia, a hypertensive disorder affecting 0.2-9.2% of pregnancies, is another leading cause of maternal and fetal complications. The relationship between UTIs and preeclampsia remains controversial, with some studies suggesting an association while others show conflicting results. Research gaps highlight the need for region-specific studies, particularly in Pakistan, where both conditions contribute significantly to maternal and neonatal morbidity.\n\nThis study aims to investigate the association between UTIs and preeclampsia in pregnant women in Pakistan. It will use a cohort design, enrolling 160 patients (80 with UTIs, 80 without) from the Obstetrics Department of PAF Hospital, Islamabad. Participants will be followed until delivery, with preeclampsia diagnosed based on blood pressure and proteinuria criteria. Data will be analyzed using SPSS to calculate relative risk (RR), with statistical significance set at RR \\>1 and p ≤ 0.05. The findings could help improve prenatal care and reduce adverse outcomes in high-risk populations.",[62,63],"Urinary Tract Infection (Diagnosis)","Preeclampsia",[63,65,66,67],"Pregnancy","Urinary tract infection","Term Birth","RECRUITING","2025-04-29",{"date":71,"type":40},"2025-05-08",{"date":73,"type":40},"2025-01-01",{"date":75,"type":21},"2025-04-30",{"name":46,"class":47},""]