[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Pakistan Institute of Living and Learning\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":275},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,10,0,[8,41,63,85,117,149,172,200,231,251],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":16,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100511008","culturally-adapted-strong-families-programme-for-families-living-in-gilgit-baltistan-pakistan-100511008",false,"NCT05933850","Culturally Adapted Strong Families Programme for Families Living in Gilgit Baltistan, Pakistan","Culturally Adapted Strong Families Programme to Improve Child Behavior and Family Functioning in Families Living in Gilgit Baltistan, Pakistan","Inclusion Criteria:\n\n* Female primary caregiver to a child aged between 8-15 years\n* Able to speak and understand Urdu language\n* Capable to give informed consent\n\nExclusion Criteria:\n\n* Families that had already taken part in another family skills training programme in the past 6 months or where the caregiver lived separately from the child\n* Not the primary caregiver of the child\n* Unlikely to be available for the duration of the whole study and outcome assessments (e.g., temporary residence).",true,"FEMALE","18 Years",{"count":20,"type":21},90,"ESTIMATED","INTERVENTIONAL",[24],"NA","The aim of this exploratory study is to test the Strong Family (SF) programme in improving family functioning. Participants will be randomized to one of the two study arms 1)- Intervention group in which participants will receive 3 group sessions of SF programme (8-12 families per group) 2)- Control group (control group will be in the waiting list and receive SF training sessions once the study will be completed).",[27],"Mental Health","RECRUITING","2026-05-24",{"date":31,"type":32},"2026-05-27","ACTUAL",{"date":34,"type":32},"2026-03-01",{"date":36,"type":21},"2027-03-31",{"name":38,"class":39},"Pakistan Institute of Living and Learning","OTHER",1,{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":4,"eligibilityCriteria":47,"healthyVolunteers":16,"sex":48,"minAge":18,"maxAge":4,"enrollmentInfo":49,"targetDuration":4,"studyType":22,"phases":51,"briefSummary":52,"conditions":53,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":55,"lastUpdatePostDateStruct":56,"startDateStruct":58,"completionDateStruct":60,"leadSponsor":62,"locationsCount":40},"100622665","contextualization-and-digitalization-of-whos-mental-health-action-gap-intervention-guide-substance-use-disorders-module-100622665","NCT07386574","Contextualization and Digitalization of WHO's Mental Health Action Gap Intervention Guide Substance Use Disorders Module","Testing a Contextualized and Digitalized WHO's Mental Health Action Gap Intervention Guide Substance Use Disorders Module in Primary Care Settings of Pakistan: A Feasibility Cluster Randomized Controlled Trial","Inclusion Criteria:\n\n* Primary and non-specialized healthcare providers working in the identified health facilities for this study across three targeted cities; willing to give informed consent for participation in this trial.\n\nExclusion Criteria:\n\n* Any primary and non-specialized healthcare provider who is not permanently working in the selected health facilities, has no access to a smart mobile phone and\u002For internet connection; and is uncomfortable using a mobile phone.","ALL",{"count":50,"type":21},300,[24],"The aim of study is to:\n\n1. To contextualize, adapt, customize and digitalize WHO's Mental Health Gap Action Programme Intervention Guide (e-mhGAP-IG); Substance Use Disorders Module (SUD module) V 2.0 for primary care settings (PCPs) in Pakistan.\n2. To test the feasibility and acceotability of the e-mhGAP-IG (SUD module) training program in a feasibility cluster randomized controlled (cRCT) trial to enable mental health services in primary health care settings in Pakistan.\n\nThe proposed study includes contextualization, adaptation, customization, and a feasibility cRCT of e-mhGAP-IG (SUD module) V 2.0 by constituting a combination of traditional and technological approaches of eHealth (mHealth, blended learning, and telemedicine) enabling mental health services in primary care settings to be well informed and accessible. This intervention will empower 300 Primary Care Physicians (PCPs) based in Primary Care Units (PCUs) from urban settlements and Basic Health Units (BHUs) from rural settlements in three major cities, Karachi, Lahore, and Rawalpindi, Pakistan.",[54],"Substance Use Disorder (SUD)","2026-04-29",{"date":57,"type":32},"2026-05-01",{"date":59,"type":32},"2025-01-01",{"date":61,"type":21},"2026-06",{"name":38,"class":39},{"id":64,"slug":65,"hasResults":11,"nctId":66,"briefTitle":67,"officialTitle":68,"acronym":4,"eligibilityCriteria":69,"healthyVolunteers":11,"sex":48,"minAge":70,"maxAge":71,"enrollmentInfo":72,"targetDuration":4,"studyType":22,"phases":73,"briefSummary":74,"conditions":75,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":77,"lastUpdatePostDateStruct":78,"startDateStruct":80,"completionDateStruct":81,"leadSponsor":83,"locationsCount":84},"100607441","culturally-adapted-cognitive-behavior-therapy-for-individuals-at-risk-of-first-episode-psychosis-100607441","NCT07188597","Culturally Adapted Cognitive Behavior Therapy for Individuals At Risk of First Episode Psychosis","Culturally Adapted Cognitive Behavior Therapy for Individuals At Risk of First Episode Psychosis: A Mixed Method Study","Inclusion Criteria:\n\n* Male or female help-seeking individual aged 16-35 years;\n* Score 6 or above on PQ-16\n* Meet the at risk of FEP criteria using CAARMS Operationalized Intake Criteria based on three groups (vulnerability, attenuated psychosis or brief limited intermittent psychotic symptoms group);\n* Assessed as competent to provide informed consent.\n* Give written informed consent.\n\nExclusion Criteria:\n\n* Temporary resident unlikely to be available for follow up.\n* Unable to engage, participate or respond to research questionnaires.\n* a history of psychotic illness (treated or untreated).\n* previous treatment with an antipsychotic or mood-stabilising agent.\n* active substance abuse (except nicotine or caffeine) or dependence within the last three months, according to DSM-V criteria.","16 Years","35 Years",{"count":20,"type":21},[24],"Young people constitute nearly half of Pakistan's population and are highly vulnerable to risk factors for mental illness, including poverty, inequality, abuse, and violence. Estimates suggest that 19-34% of children and adolescents experience emotional or behavioural disorders, though this is likely underestimated. In recent years, research has focused on those at imminent risk of developing serious conditions such as first episode psychosis. The concept of an At-Risk Mental State (ARMS) has highlighted the urgent need for interventions that address current symptoms, improve functioning, and reduce transition to psychosis.\n\nUp to 80% of young people with ARMS have another diagnosable condition, and almost half show poor psychosocial outcomes even six years after initial help-seeking. Evidence demonstrates that early identification and treatment can delay or prevent psychosis, including severe and enduring illnesses like schizophrenia. Cognitive Behaviour Therapy (CBT) is among the most effective evidence-based approaches for this group. However, existing evidence comes largely from high-income countries, raising concerns about cultural applicability in low-resource settings.\n\nThis study will culturally adapt and field test a manualised CBT intervention for young people at risk of first episode psychosis. To our knowledge, this is the first such study in a low-income country. Findings will inform scalable, culturally relevant interventions for Pakistan and similar contexts.",[76],"Individuals at Risk of First Episode Psychosis","2026-04-06",{"date":79,"type":32},"2026-04-13",{"date":59,"type":32},{"date":82,"type":21},"2026-12-30",{"name":38,"class":39},2,{"id":86,"slug":87,"hasResults":11,"nctId":88,"briefTitle":89,"officialTitle":90,"acronym":91,"eligibilityCriteria":92,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":93,"targetDuration":4,"studyType":22,"phases":95,"briefSummary":96,"conditions":97,"keywords":100,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":109,"lastUpdatePostDateStruct":110,"startDateStruct":112,"completionDateStruct":114,"leadSponsor":116,"locationsCount":40},"100594169","moving-on-after-breast-cancer-trial-for-depressed-breast-cancer-survivors-in-pakistan-100594169","NCT07015944","Moving on After Breast Cancer Trial for Depressed Breast Cancer Survivors in Pakistan","Clinical and Cost-effectiveness of an Integrated Psychosocial Care Plan for Comorbid Depression in Breast Cancer Survivors In Pakistan: A Sequential Multiple Assignment Randomised Trial","Moving On ABC","Inclusion Criteria:\n\n* Women\n* Aged 18 years and above\n* Diagnosed with breast cancer (any stage)\n* Completed initial treatment (i.e., surgery and\u002For radiotherapy or chemotherapy) for breast cancer (even if they are currently on hormonal therapy post-initial treatment)\n* Total score of 10 or above on the Patient Health Questionnaire (PHQ-9)\n* Diagnosis of current Major Depressive Episode (MDE) confirmed using the Structured Clinical Interview for DSM-5 (SCID).\n\nExclusion Criteria:\n\n* Lacking capacity to provide informed consent, such as those identified by clinicians as having intellectual disabilities, dementia, or severe medical and\u002For psychiatric illnesses requiring hospitalisation\n* Unable to engage in assessments or interventions, including those with stage 4 breast cancer experiencing significant symptoms (e.g., metastatic lesions in the lungs, liver, or bones requiring daily treatment for symptomatic relief, such as the daily use of two or more painkillers), which restrict their capacity to participate\n* Currently receiving psychological therapy or taking antidepressant medications (e.g., SSRIs, SNRIs, or other prescribed antidepressants)",{"count":94,"type":21},26376,[24],"Breast cancer is the most common cancer among women worldwide, and many survivors experience comorbid mental health conditions such as depression and anxiety, which can significantly worsen health outcomes and increase mortality. This large-scale trial in Pakistan aims to evaluate the clinical and cost-effectiveness of a three-stage adaptive intervention to manage depression among breast cancer survivors. Using a Sequential, Multiple Assignment, Randomised Trial (SMART) design, the study will recruit 26,372 participants aged 18 and above who have completed initial breast cancer treatment (surgery and\u002For chemotherapy or radiotherapy). Participants will be identified through primary care units, outpatient departments, oncology clinics in public hospitals, and charitable organisations across Pakistan. Depression will be screened using the Patient Health Questionnaire PHQ-9, with diagnosis confirmed by the Structured Clinical Interview Schedule of DSM (SCID). Those randomised to the intervention arm will receive adaptive interventions: starting with low-intensity guided self-help, followed by a high-intensity cognitive behavioural therapy-based programme called \"Moving On After Breast Cancer Plus\" (Moving on ABC Plus), and for non-responders, an additional pharmacological component will be introduced. Participants in both adaptive intervention and enhance usual care groups will be assessed at multiple time points-baseline, 6, 18, 30, and 48 weeks post-randomisation-using validated tools to measure depression (primary outcome), and anxiety, self-esteem, intrusive thoughts, health-related quality of life, satisfaction with services, and health resource use (secondary outcomes). The study will also include qualitative interviews and focus groups discussions with patients, caregivers, healthcare providers, and policymakers to identify barriers and facilitators to implementation and ensure the intervention is both contextually appropriate and scalable.",[98,99],"Major Depressive Disorder (MDD)","Breast Cancer Survivor",[101,102,103,104,105,106,107,108],"Breast Cancer","LMICs","Depression","Multimorbidity","SMART","Adaptive interventions","Cognitive Behaviour Therapy","Low intensity intervention","2026-03-16",{"date":111,"type":32},"2026-03-18",{"date":113,"type":32},"2025-06-13",{"date":115,"type":21},"2028-12-30",{"name":38,"class":39},{"id":118,"slug":119,"hasResults":11,"nctId":120,"briefTitle":121,"officialTitle":122,"acronym":123,"eligibilityCriteria":124,"healthyVolunteers":11,"sex":48,"minAge":18,"maxAge":4,"enrollmentInfo":125,"targetDuration":4,"studyType":22,"phases":127,"briefSummary":128,"conditions":129,"keywords":133,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":140,"lastUpdatePostDateStruct":141,"startDateStruct":143,"completionDateStruct":145,"leadSponsor":147,"locationsCount":148},"100559082","integrated-case-management-for-burns-care-in-pakistan-100559082","NCT06559501","Integrated Case Management for Burns Care in Pakistan","Integrated Case Management for Improved Psychosocial and Physical Rehabilitation of Burn Survivors and Their Families Treated in Pakistan","BURNS","Inclusion Criteria:\n\n* Adults 18 years and over\n* Accidental burn injury and meet the criteria for admission to burn centres\n* Clinician judgment for participation readiness\n* Ability to provide informed consent\n\nExclusion Criteria:\n\nNo intentional burn injuries\n\n• Lacking capacity to provide informed consent",{"count":126,"type":21},1146,[24],"To test whether a culturally adapted multicomponent intervention for improving burns care and patient\u002Ffamily rehabilitation is effective in improving survival among burn victims in Pakistan and is cost-effective. The comparator will be usual care plus brief written self-help advice (enhanced usual care). The study is designed as a multicentre, pragmatic, parallel group, individually randomised trial. Participants in the intervention arm will receive 8 sessions delivered by the case managers (6 low-intensity sessions lasting 30-60 minutes in the hospital\u002Fcommunity and 2 follow-up sessions lasting 30 minutes in the community). Assessments will be conducted at baseline, at 3 months, 6 months and at 12-months post-intervention.",[130,103,131,132],"Unintentional Burn Injury","Anxiety","Burns",[134,135,136,137,138,139],"Burns Rehabilitation","culturally adapted","Cost effectiveness","Multicenter trial","Pakistan","Burns Injury","2025-07-29",{"date":142,"type":32},"2025-07-30",{"date":144,"type":32},"2024-09-02",{"date":146,"type":21},"2026-10-31",{"name":38,"class":39},11,{"id":150,"slug":151,"hasResults":11,"nctId":152,"briefTitle":153,"officialTitle":154,"acronym":155,"eligibilityCriteria":156,"healthyVolunteers":11,"sex":48,"minAge":18,"maxAge":4,"enrollmentInfo":157,"targetDuration":4,"studyType":22,"phases":159,"briefSummary":160,"conditions":161,"keywords":163,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":59,"lastUpdatePostDateStruct":165,"startDateStruct":167,"completionDateStruct":169,"leadSponsor":171,"locationsCount":40},"100495204","psychosocial-intervention-for-suicidal-ideation-in-individuals-with-fep-a-feasibility-trial-100495204","NCT05728138","Psychosocial Intervention for Suicidal Ideation in Individuals With FEP: A Feasibility Trial","Culturally Adapted Psychosocial Intervention for Suicidal Ideation in Individuals With First Episode Psychosis: A Feasibility Randomised Controlled Trial","CMAP-FEP","Inclusion Criteria:\n\n* Individuals diagnosed with, Schizophrenia or Schizoaffective disorder according to DSM-V, confirmed by treating consultant.\n* Age 18 and above years able to understand written and spoken Urdu.\n* A score of 1 (Mild- Frequent thoughts of being better off dead, or occasional thoughts of suicide.) on the Calgary depression Scale item 8 (Suicide) \"Have you felt that life wasn't worth living? Did you ever feel like ending it all? What did you think you might do? Did you actually try?\"\n* Individuals with a score of 3 or more on any of the positive symptoms on the Positive and Negative Syndrome Scale (PANSS) (e.g., delusions, hallucination).\n\nExclusion Criteria:\n\n* Any evidence of organic brain disease, clinically significant comorbid illness or learning disability. Participants deemed actively suicidal by their designated health professional.\n* Those scoring \\>1 on Calgary depression Scale will be excluded and be referred to a psychiatric service.",{"count":158,"type":21},80,[24],"To check the feasibility and acceptability of Culturally adapted Cognitive Behavioral Therapy for Psychosis (CaCBTp) and Culturally Adapted Manual Assisted Brief Psychological Intervention for Self-harm (CMAP), which we have provisionally called (CMAP Plus) for individuals experiencing Suicidal Ideation (SI) in First Episode Psychosis (FEP).",[162],"Self Harm, First Episode Psychosis",[164],"Self-harm, First Episode Psychosis, adaptation, problem-solving.",{"date":166,"type":32},"2025-01-03",{"date":168,"type":32},"2023-11-01",{"date":170,"type":21},"2025-10-30",{"name":38,"class":39},{"id":173,"slug":174,"hasResults":11,"nctId":175,"briefTitle":176,"officialTitle":177,"acronym":178,"eligibilityCriteria":179,"healthyVolunteers":16,"sex":48,"minAge":18,"maxAge":4,"enrollmentInfo":180,"targetDuration":4,"studyType":22,"phases":182,"briefSummary":183,"conditions":184,"keywords":186,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":192,"lastUpdatePostDateStruct":193,"startDateStruct":195,"completionDateStruct":197,"leadSponsor":199,"locationsCount":40},"100501873","culturally-adapted-psychosocial-interventions-for-early-psychosis-in-a-low-resource-setting-100501873","NCT05814913","Culturally Adapted Psychosocial Interventions for Early Psychosis in a Low-resource Setting","Culturally Adapted Psychosocial Interventions for Early Psychosis in a Low-resource Setting: a Large Multi-center Randomised Controlled Trial","CaPSI","Inclusion Criteria for patient participants:\n\n* Individuals of all genders aged over 18 years; diagnosis of schizophrenia confirmed by Structured Clinical Interview for DSM (SCID) meeting DSM-5 criteria for schizophrenia, schizophreniform or schizoaffective psychosis\n* Scored at least 4 on the PANSS delusions or hallucinations items, or at least 5 on suspiciousness, persecution, or grandiosity items\n* stable on medication for the past four weeks\n* in contact with mental health services\n* within 3 years of diagnosis\n* able to demonstrate the capacity to provide informed consent to take part in the study\n* potential participants must have a carer or relative who is also willing to participate in the study to be eligible\n\nExclusion Criteria for patient participants:\n\n* Active DSM-5 substance use disorder (except nicotine or caffeine) or dependence within the last three months\n* A score of 5 or more on the PANSS conceptual disorganisation item\n* Individuals who have received structured psychological intervention within the past 3 months\n* Relevant CNS or other medical disorders that would impact participation\n* Diagnosis of intellectual disability\n* Unstable residential arrangements\n\nFamily member\u002FCarer participant inclusion criteria:\n\n* Living with or spending at least 10 hours per week in face-to-face contact with an individual with early psychosis and assuming a caring role\n* Age\\>18 years\n* Able to give informed written consent.\n\nFamily member\u002FCarer participant exclusion criteria:\n\n* Active DSM-5 substance use disorder\n* Received psychological intervention within the past 3 months\n* Unstable residential arrangements.",{"count":181,"type":21},390,[24],"Primary Aims:\n\nTo determine the clinical efficacy of Culturally adapted Cognitive Behavioral Therapy (CaCBT) and Culturally adapted Family Intervention (CulFI) compared to Treatment As Usual (TAU) on reducing overall symptoms of psychosis in patients with First Episode Psychosis (FEP) in Pakistan.\n\nSecondary Aims:\n\n1. To determine the efficacy of CaCBT and CulFI compared to TAU on positive and negative symptoms of psychosis, general psychopathology, depressive symptoms, quality of life, general functioning, and insight in patients with FEP in Pakistan.\n2. To determine the efficacy of CaCBT and CulFI compared to TAU on improving carer experience, carer wellbeing, carer illness attitudes and symptoms of depression and anxiety in family and carers of patients with FEP in Pakistan.\n3. To determine the comparative effect of CaCBT and CulFI in improving patient and carer related outcomes in individuals with FEP in Pakistan.\n4. To estimate the economic impact of delivering culturally appropriate psychosocial interventions in low-resource settings\n5. To explore delivery and reach of each intervention, tolerability of intervention components, acceptability of interventions, understanding mechanism of change and developing an understanding of barriers and facilitators to future adoption using process evaluation.\n\nStudy design and setting:\n\nThis will be a multi-centre, assessor masked, individual, three-arm randomised controlled trial (RCT).\n\nSample Size:\n\nThe study aims to recruit a total of N=390 participants with FEP",[185],"Psychosis",[187,188,189,190,191],"First Episode Psychosis","LAMIC","Family Intervention","CBT","Paksitan","2024-12-07",{"date":194,"type":32},"2024-12-12",{"date":196,"type":32},"2024-04-15",{"date":198,"type":21},"2026-12-31",{"name":38,"class":39},{"id":201,"slug":202,"hasResults":11,"nctId":203,"briefTitle":204,"officialTitle":205,"acronym":206,"eligibilityCriteria":207,"healthyVolunteers":16,"sex":48,"minAge":208,"maxAge":209,"enrollmentInfo":210,"targetDuration":4,"studyType":22,"phases":212,"briefSummary":213,"conditions":214,"keywords":216,"overallStatus":222,"whyStopped":4,"lastUpdateSubmitDate":223,"lastUpdatePostDateStruct":224,"startDateStruct":226,"completionDateStruct":228,"leadSponsor":230,"locationsCount":40},"100550049","universally-delivered-interventions-for-young-people-100550049","NCT06442007","Universally Delivered Interventions for Young People","A 3-arm Multi-Center Exploratory Trial of Universally Delivered Interventions for Prevention of Anxiety and Depression in Young People in Pakistan","Mindset-PK","Young persons (YP)\n\nInclusion Criteria:\n\n* Youth is between the age 12-15 years (inclusive) at the time of study enrollment.\n* Youth has one parent or legal guardian to give consent.\n* Youth speaks Urdu well enough to complete the paper based intervention.\n\nExclusion Criteria:\n\n* Intellectual disability, as this may undermine comprehension of intervention material.\n* Adolescent with history of hospitalization or those who received inpatient treatment for a mental health problem within the past two months as the intervention being tested and this study is not designed for adolescent with acute medical and\u002For psychiatric treatment needs (if identified with any acute medical and\u002For psychiatric problem, they would be referred to appropriate health services through parents).\n\nSchools Inclusion Criteria\n\nSchools in the study areas are eligible to participate if they meet all the following criteria:\n\n1. the school authority agrees to participate;\n2. the schools shall be non-specialist public schools;\n3. school contains at least 80 students; Exclusion criteria\n\nIf the school meet the following exclusion criteria, they are ineligible to participate:\n\n1. the school authority refuses to participate;\n2. a specialist and\u002For independent or private school;","12 Years","15 Years",{"count":211,"type":21},564,[24],"Mental health problems are amongst the major contributors to disease burden globally.\n\nAccording to a recent study, 34% of young people worldwide (aged 10-19) suffer from depression and more than half of this population belongs to Southeast Asia such as Pakistan, India, and China.\n\nExisting evidence shows that the access to mental health services in LMICs is limited and even fewer child psychiatric services are available.\n\nOne approach to overcome barriers such as limited availability of trained mental health professionals and risk of stigma may involve the use of simple, brief, scalable interventions based on basic psychological principles rather than treatment of psychopathology.\n\nThis study adapts and evaluates two brief interventions called behavioral activation single session intervention (BA-SSI) and 4-session Mindset intervention (MI) for teenage depression and anxiety in Pakistan, where access to mental health care is constrained by societal stigma and a shortage of clinicians.",[215],"Distress, Emotional",[217,218,219,220,221,138],"adolescents","anxiety","depression","single session interventions","growth mindset","NOT_YET_RECRUITING","2024-12-05",{"date":225,"type":32},"2024-12-10",{"date":227,"type":21},"2025-05-01",{"date":229,"type":21},"2025-12-30",{"name":38,"class":39},{"id":232,"slug":233,"hasResults":11,"nctId":234,"briefTitle":235,"officialTitle":236,"acronym":4,"eligibilityCriteria":237,"healthyVolunteers":11,"sex":48,"minAge":18,"maxAge":4,"enrollmentInfo":238,"targetDuration":4,"studyType":22,"phases":240,"briefSummary":241,"conditions":242,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":243,"lastUpdatePostDateStruct":244,"startDateStruct":246,"completionDateStruct":248,"leadSponsor":250,"locationsCount":40},"100430476","culturally-adapted-motivational-interviewing-with-cbt-and-mindfulness-based-relapse-prevention-for-substance-use-disorder-in-pakistan-camiab-100430476","NCT04885569","Culturally Adapted Motivational Interviewing With CBT and Mindfulness Based Relapse Prevention for Substance Use Disorder in Pakistan (CAMIAB)","Feasibility Study of Culturally Adapted Cognitive Behavioral Therapy Based Integrated Motivational Interviewing and Mindfulness Intervention for Substance Use Disorder in Pakistan (CAMIAB)","Inclusion Criteria\n\n* Participants with substance use disorder\n* Meeting DSM-V criteria for substance use disorder\n* Age 18 years and above\n* Being able to understand spoken or written Urdu\n* Have undergone through the process of detoxification before study intervention\n\nExclusion Criteria\n\n• Any evidence of organic brain disease, clinically significant cooccurring medical illness or mental illness to the extent that can impede their ability to provide informed consent or engagement in the intervention.",{"count":239,"type":21},260,[24],"The study has both quantitative and qualitative components. The aim of study is to:\n\n1. Culturally adapt and integrate the existing Motivational Interviewing with Cognitive Behavioral Therapy(MICBT) and Mindfulness based Relapse Prevention (MBRP) for people with Substance Use Disorder (SUD) in Pakistan\n2. Test the feasibility and acceptability of the integrated intervention called CAMIAB ('CAMIAB' means success in Urdu) in a randomized control trial (RCT).",[54],"2024-09-03",{"date":245,"type":32},"2024-09-19",{"date":247,"type":32},"2023-12-01",{"date":249,"type":21},"2025-06",{"name":38,"class":39},{"id":252,"slug":253,"hasResults":11,"nctId":254,"briefTitle":255,"officialTitle":256,"acronym":4,"eligibilityCriteria":257,"healthyVolunteers":11,"sex":17,"minAge":70,"maxAge":258,"enrollmentInfo":259,"targetDuration":4,"studyType":22,"phases":260,"briefSummary":261,"conditions":262,"keywords":264,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":267,"lastUpdatePostDateStruct":268,"startDateStruct":270,"completionDateStruct":272,"leadSponsor":274,"locationsCount":40},"100504744","a-problem-solving-intervention-for-women-with-suicidal-ideation-during-postnatal-period-in-pakistan-100504744","NCT05852314","A Problem-Solving Intervention for Women With Suicidal Ideation During Postnatal Period in Pakistan","Culturally Adapted Manual-Assisted Problem-Solving Intervention for Women With Suicidal Ideation in Postnatal Period in Pakistan: A Feasibility Trial","Inclusion Criteria:\n\n1. 16 to 44-year-old mothers with children 0 - 30 months old\n2. Residents of the trial site catchments area\n3. Able to provide informed consent\n4. Presenting with suicidal ideation as measured by the Beck Suicidal Ideation Scale (BSSI) (must score 1 or 2 on item 4 and 5)\n5. Not requiring in-patient psychiatric treatment.\n\nExclusion Criteria:\n\nWe will exclude mothers with any physical or psychiatric condition severe enough to prevent study participation.","44 Years",{"count":20,"type":21},[24],"The aim of this study is to determine the feasibility and acceptability of culturally adapted CMAP for suicidal Ideation for women in postnatal period.\n\nObjectives\n\n1. To adapt existing CMAP Intervention for suicidal ideation (CMAP-SI) in postnatal period.\n2. To investigate whether CMAP-SI is feasible and acceptable among women presenting suicidal Ideations in postnatal period; and\n3. To test whether there is an indication for the effects of the CMAP in reducing suicidal thoughts among women in postnatal period.\n4. To explore participants experiences with CMAP-SI Intervention.",[263],"Postnatal Depression",[263,265,102,266],"Suicidal Ideation","CMAP","2024-08-09",{"date":269,"type":32},"2024-08-12",{"date":271,"type":32},"2023-07-10",{"date":273,"type":21},"2024-12",{"name":38,"class":39},""]