[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Pamukkale University\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":631},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,33,0,25,[9,40,68,92,117,141,167,195,220,239,269,297,319,344,368,394,418,444,465,490,511,536,563,587,612],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":15,"acronym":4,"eligibilityCriteria":16,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":22,"studyType":23,"phases":4,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":28,"lastUpdatePostDateStruct":29,"startDateStruct":32,"completionDateStruct":34,"leadSponsor":36,"locationsCount":39},"100053893","the-kings-brief-lnterstitial-lung-disease-questionnaire-100053893",false,"NCT07700004","The King's Brief Lnterstitial Lung Disease Questionnaire","Investigation of the Turkish Validity and Reliability of The King's Brief Interstitial Lung Disease Questionnaire (K-BILD) in Individuals With Interstitial Lung Involvement Secondary to Rheumatological Diseases","Inclusion Criteria:-Having been diagnosed with interstitial lung disease by a rheumatologist,\n\n* Being 18 years of age or older,\n* Agreeing to participate in the study.\n\nExclusion Criteria:- Presence of a neurological disease\n\n* Presence of any orthopedic problem that affects functionality\n* History of any orthopedic surgery in the last year\n* Inability to speak or understand Turkish fluently\n* Presence of a psychiatric illness that affects cooperation\n* Heart failure that affects daily living activities\n* Being a cancer patient","ALL","18 Years",{"count":20,"type":21},45,"ESTIMATED","1 Day","OBSERVATIONAL","The aim of this study is to examine the validity and reliability of the Turkish Validity and Reliability of The King's Brief Interstitial Lung Disease Questionnaire (K-BILD) in Individuals with Interstitial Lung Involvement Secondary to Rheumatological Diseases.",[26],"Interstitial Lung Disease Due to Systemic Disease","NOT_YET_RECRUITING","2026-07-07",{"date":30,"type":31},"2026-07-13","ACTUAL",{"date":33,"type":21},"2026-07-05",{"date":35,"type":21},"2027-05-15",{"name":37,"class":38},"Pamukkale University","OTHER",1,{"id":41,"slug":42,"hasResults":12,"nctId":43,"briefTitle":44,"officialTitle":45,"acronym":46,"eligibilityCriteria":47,"healthyVolunteers":48,"sex":17,"minAge":18,"maxAge":49,"enrollmentInfo":50,"targetDuration":4,"studyType":52,"phases":53,"briefSummary":55,"conditions":56,"keywords":4,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":61,"startDateStruct":63,"completionDateStruct":65,"leadSponsor":67,"locationsCount":39},"100641580","effects-of-passive-recovery-methods-after-high-intensity-cycling-exercise-100641580","NCT07652398","Effects of Passive Recovery Methods After High-Intensity Cycling Exercise","Acute Effects of Five Passive Recovery Interventions Following High-Intensity Cycling Exercise: A Randomized Five-Period Crossover Trial","RECOVER-CYCLE","Inclusion Criteria:\n\n* Healthy adult volunteers aged 18-35 years\n* Able to perform high-intensity cycling exercise\n* No musculoskeletal injury within the last six months\n* No known cardiovascular, neurological, or metabolic disease\n* Not using medication that may affect exercise performance, pain perception, or recovery\n* Willing to attend all five study sessions\n* Willing to receive all five passive recovery interventions\n* Provided written informed consent\n\nExclusion Criteria:\n\n* Presence of acute or chronic musculoskeletal injury\n* History of cardiovascular, neurological, respiratory, or metabolic disease\n* Contraindication to high-intensity exercise\n* Contraindication to compression therapy, vacuum therapy, kinesiology taping, passive rest, or classical massage\n* Skin allergy, open wound, dermatological disease, or sensitivity to kinesiology tape\n* Use of analgesic, anti-inflammatory, muscle relaxant, or performance-enhancing medication during the study period\n* Participation in another exercise or recovery intervention study during the study period\n* Failure to attend all study sessions or comply with study procedures",true,"30 Years",{"count":51,"type":21},10,"INTERVENTIONAL",[54],"NA","This randomized crossover trial will investigate the acute effects of five passive recovery interventions following a standardized high-intensity cycling exercise protocol. Participants will complete one supervised high-intensity cycling session per week for five consecutive weeks. Immediately after each exercise session, participants will receive one of five recovery interventions: compression therapy, vacuum therapy, kinesiology taping, passive rest, or classical massage. The order of the interventions will be randomized according to a balanced crossover sequence. Each participant will experience all five recovery interventions during the study period. Outcomes related to post-exercise recovery will be assessed across intervention periods.",[57,58],"Young Adult Health","Young Adult Females","RECRUITING","2026-06-26",{"date":62,"type":31},"2026-06-30",{"date":64,"type":31},"2026-06-22",{"date":66,"type":21},"2027-08-28",{"name":37,"class":38},{"id":69,"slug":70,"hasResults":12,"nctId":71,"briefTitle":72,"officialTitle":73,"acronym":4,"eligibilityCriteria":74,"healthyVolunteers":12,"sex":75,"minAge":18,"maxAge":49,"enrollmentInfo":76,"targetDuration":4,"studyType":52,"phases":78,"briefSummary":79,"conditions":80,"keywords":82,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":60,"lastUpdatePostDateStruct":87,"startDateStruct":88,"completionDateStruct":89,"leadSponsor":91,"locationsCount":39},"100642780","connective-tissue-massage-and-music-based-progressive-muscle-relaxation-in-primary-dysmenorrhea-100642780","NCT07647276","Connective Tissue Massage and Music-Based Progressive Muscle Relaxation in Primary Dysmenorrhea","The Effects of Connective Tissue Massage and Music-Based Progressive Muscle Relaxation on Pain Intensity, Pressure Pain Threshold, and Menstruation-Related Symptoms in Women With Primary Dysmenorrhea: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Having a diagnosis of primary dysmenorrhea made by a Gynecology and Obstetrics specialist\n* Being between 18-30 years of age\n* Being nulliparous\n* Having a regular menstrual cycle (28 ± 7 days)\n* Having menstrual pain intensity greater than 4 cm on the Visual Analog Scale for the last 6 months\n* Voluntarily agreeing to participate in the study\n\nExclusion Criteria:\n\n* Having been diagnosed at least 6 months prior with gastrointestinal, urogynecological, autoimmune, or psychiatric diseases and\u002For chronic pain syndromes\n* Having any neurological or systemic disease\n* Having a history of childbirth or previous pregnancy\n* Being pregnant\n* Using an intrauterine device (IUD)\n* Having any pelvic pathology or history of pelvic surgery\n* Chronic use of medications, including oral contraceptives or antidepressants\n* Currently receiving anti-inflammatory, analgesic, or psychotherapeutic drug treatment\n* Having irregular menstrual cycles (\\\u003C21 or \\>35 days and\u002For cycle variation \\>4 days)\n* Presence of pathology indicating secondary dysmenorrhea","FEMALE",{"count":77,"type":21},36,[54],"This randomized controlled clinical trial aims to investigate the effects of Connective Tissue Massage (CTM) and music-based Progressive Muscle Relaxation Training (PMRT) on pain intensity, pressure pain threshold, analgesic use, and menstruation-related symptoms in women with primary dysmenorrhea. Participants will be randomly assigned to one of three groups: CTM, music-based PMRT, or control. Baseline assessment will be conducted during menstrual days 1-2 of Cycle 0. The interventions will be applied during the premenstrual intervention window of Cycle 0, from the estimated ovulation day, calculated as cycle length minus 14 days, until Cycle 1 Day 1. Post-intervention assessment will be conducted during menstrual days 1-2 of Cycle 1. No intervention will be applied after the post-intervention assessment, and follow-up assessment will be conducted during menstrual days 1-2 of Cycle 2. Outcomes including pain intensity, pressure pain threshold, analgesic use, menstrual symptoms, attitudes toward menstruation, functional and emotional impact of dysmenorrhea, and pain catastrophizing will be evaluated across menstrual cycles. Participant satisfaction and adherence to the interventions will also be assessed.",[81],"Primary Dysmenorrhea",[83,84,85,86],"Primary dysmenorrhea","Connective tissue massage","Progressive muscle relaxation training","Pain",{"date":62,"type":31},{"date":64,"type":31},{"date":90,"type":21},"2026-11-15",{"name":37,"class":38},{"id":93,"slug":94,"hasResults":12,"nctId":95,"briefTitle":96,"officialTitle":97,"acronym":4,"eligibilityCriteria":98,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":99,"targetDuration":4,"studyType":52,"phases":101,"briefSummary":102,"conditions":103,"keywords":105,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":110,"lastUpdatePostDateStruct":111,"startDateStruct":112,"completionDateStruct":114,"leadSponsor":116,"locationsCount":39},"100642023","comparison-of-the-effects-of-two-different-exercise-programs-on-femoral-cartilage-thickness-and-clinical-parameters-in-individuals-with-knee-osteoarthritis-100642023","NCT07657481","Comparison of the Effects of Two Different Exercise Programs on Femoral Cartilage Thickness and Clinical Parameters in Individuals With Knee Osteoarthritis","Comparison of the Effects of Two Different Home Exercise Programs on Femoral Cartilage Thickness and Clinical Parameters in Individuals With Knee Osteoarthritis: A Randomized Controlled Trial","Inclusion Criteria:\n\n1. Age ≥18 years\n2. Diagnosis of knee osteoarthritis according to ACR criteria, Kellgren-Lawrence grade 2-3\n3. Knee pain for at least 3 months\n4. Having the physical capacity to perform a home exercise program\n5. Willingness to provide written informed consent\n\nExclusion Criteria:\n\n1. History of knee, hip, or spine surgery\n2. Active inflammatory arthritis (e.g., rheumatoid arthritis, gout, psoriatic arthritis)\n3. Intra-articular injection within the last 3 months\n4. Neurological or neuromuscular disorders\n5. Body mass index (BMI) \\> 40 kg\u002Fm²\n6. Pregnancy\n7. Cardiovascular or orthopedic contraindications preventing participation in a regular exercise program\n8. Cognitive impairment",{"count":100,"type":21},56,[54],"Knee osteoarthritis (OA) is one of the most common joint disorders worldwide and is a leading cause of pain, limited mobility, and functional disability, particularly in the elderly population. According to 2020 data, approximately 654 million individuals aged 40 years and older are affected by knee OA worldwide, with a global prevalence of 22.9% in this age group. In our country as well, OA is reported as the second most common rheumatologic disease. The disease not only negatively affects individuals' quality of life but also creates a significant socioeconomic burden through work loss, hospital admissions, and the need for surgical interventions.\n\nThe pathogenesis of knee OA is a complex process involving articular cartilage degeneration, subchondral bone sclerosis, synovial tissue proliferation, and osteophyte formation. Once cartilage damage begins, its capacity for spontaneous healing is extremely limited; therefore, early interventions aimed at slowing or halting disease progression are of critical importance. In this context, non-pharmacological interventions, particularly exercise programs that may contribute to maintaining cartilage integrity, are strongly recommended as first-line treatment options in current clinical guidelines.\n\nThe beneficial effects of exercise therapy on pain and function in patients with knee OA are well documented. However, the structural effects of exercise on femoral cartilage thickness have been relatively less investigated. Tuna et al. evaluated femoral cartilage thickness using ultrasonography in 40 patients with knee OA following a 12-week quadriceps strengthening program and reported statistically significant increases in cartilage thickness in the medial condyle, lateral condyle, and intercondylar region at 3 months. This pioneering study suggests that muscle strengthening programs may have not only symptomatic but also structural benefits. Similarly, Bozan et al. reported a strong positive correlation between quadriceps muscle thickness (rectus femoris + vastus intermedius) and femoral cartilage thickness, supporting the idea that muscle loss parallels cartilage degeneration. However, these studies focused exclusively on the quadriceps muscle, and the effects of hip musculature on femoral cartilage thickness have not been investigated. Recent biomechanical studies indicate that hip abductor and adductor muscles play a critical role in knee joint loading patterns.\n\nHip abductor muscles provide pelvic stability during gait and directly influence knee adduction moments. Weakness of the gluteus medius leads to contralateral pelvic drop, increasing medial compartment loading on the ipsilateral knee and accelerating medial tibiofemoral cartilage wear. Indeed, Segal et al., using data from the Multicenter Osteoarthritis Study (MOST), demonstrated via MRI that greater hip abductor strength significantly reduces the risk of progression of medial patellofemoral and lateral tibiofemoral cartilage damage. On the other hand, hip adductor muscles are also thought to contribute to knee adduction moments by eccentrically controlling femoral varus motion; however, this relationship has been studied far less compared to quadriceps and abductors.\n\nSystematic reviews and meta-analyses have shown that individuals with knee OA have up to 24% lower isometric hip abductor strength compared to healthy controls. Randomized controlled trials investigating combined hip and quadriceps strengthening programs have reported significant improvements in pain and function. However, none of these studies have used femoral cartilage thickness measured by ultrasonography as a primary outcome.\n\nA review of the current literature reveals that although studies exist examining the effects of quadriceps strengthening on femoral cartilage thickness, no randomized controlled trial has compared hip abductor and adductor strengthening exercises with a quadriceps strengthening program, using ultrasonographic femoral cartilage thickness as the primary outcome measure. This study aims to address this gap. All interventions will be applied as non-invasive home exercise programs, and all measurements will be performed using ultrasonography. Baseline, 1-month, and 3-month assessments will also allow evaluation of the temporal effects of exercise on cartilage structure. The findings are expected to provide scientific evidence regarding the structural protective effects of hip exercises in knee OA rehabilitation and serve as pilot data for future large-scale multicenter studies.\n\nThe aim of this study is to compare patients with knee OA receiving quadriceps strengthening exercises alone with those receiving additional hip abductor\u002Fadductor strengthening exercises in terms of changes in femoral cartilage thickness, and to evaluate whether there is a correlation between femoral cartilage thickness and the thickness of the rectus femoris, gluteus medius,",[104],"Osteo Arthritis of the Knee",[106,107,108,109],"knee osteoartritis","femoral cartilage thikness","quadriceps strengthening exercises","hip abductor and adductor strengthening exercises","2026-06-17",{"date":64,"type":31},{"date":113,"type":21},"2026-08-20",{"date":115,"type":21},"2027-07-01",{"name":37,"class":38},{"id":118,"slug":119,"hasResults":12,"nctId":120,"briefTitle":121,"officialTitle":122,"acronym":123,"eligibilityCriteria":124,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":125,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":127,"conditions":128,"keywords":130,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":134,"lastUpdatePostDateStruct":135,"startDateStruct":136,"completionDateStruct":138,"leadSponsor":140,"locationsCount":39},"100641704","central-sensitization-and-functional-outcomes-in-chronic-shoulder-pain-100641704","NCT07654023","Central Sensitization and Functional Outcomes in Chronic Shoulder Pain","The Effects of Central Sensitization and Psychological Factors on Functional Outcomes Following Rehabilitation in Individuals With Chronic Shoulder Pain","SHOULDER-CS","Inclusion Criteria:\n\n* Adults aged 18 years and older\n* Presence of chronic shoulder pain lasting at least 3 months\n* Clinical findings consistent with shoulder-related pain\n* Willingness to participate in a 6-week physiotherapy rehabilitation program\n* Ability to complete study assessments and questionnaires\n* Provision of written informed consent\n\nExclusion Criteria:\n\n* History of shoulder surgery within the previous 6 months\n* Major shoulder trauma within the previous 6 months\n* Serious pathology affecting the shoulder (e.g., infection, tumor, systemic inflammatory disease)\n* Neurological disorders affecting the upper extremity (e.g., cervical radiculopathy, myelopathy, peripheral nerve injury)\n* Severe cognitive impairment\n* Communication problems preventing participation\n* Shoulder injection within the previous 4 weeks\n* Pregnancy",{"count":126,"type":21},59,"This prospective observational cohort study aims to investigate whether baseline central sensitization and psychological factors predict functional outcomes following rehabilitation in individuals with chronic shoulder pain. Participants with chronic shoulder pain will receive a standardized 6-week physiotherapy and rehabilitation program routinely applied in the clinic. Assessments will be performed before and after treatment, including pain severity, shoulder function, central sensitization symptoms, and psychological factors such as pain catastrophizing. The findings of this study may contribute to a better understanding of biopsychosocial factors affecting rehabilitation outcomes in chronic shoulder pain and help improve individualized rehabilitation approaches.",[129],"Chronic Shoulder Pain",[131,132,133],"Chronic shoulder pain","Central sensitization","Physical therapy","2026-06-13",{"date":110,"type":31},{"date":137,"type":21},"2026-06-15",{"date":139,"type":21},"2026-08-01",{"name":37,"class":38},{"id":142,"slug":143,"hasResults":12,"nctId":144,"briefTitle":145,"officialTitle":146,"acronym":4,"eligibilityCriteria":147,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":148,"enrollmentInfo":149,"targetDuration":4,"studyType":52,"phases":150,"briefSummary":151,"conditions":152,"keywords":155,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":159,"lastUpdatePostDateStruct":160,"startDateStruct":162,"completionDateStruct":164,"leadSponsor":166,"locationsCount":39},"100636558","the-effect-of-kinesio-taping-on-hand-functions-in-zone-v-vi-extensor-tendon-injuries-100636558","NCT07567248","The Effect of Kinesio Taping on Hand Functions in Zone V-VI Extensor Tendon Injuries","Investigation of the Effect of Kinesio Taping on Hand Functions in Zone V-VI Extensor Tendon Injuries: A Double-Blind Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n* Aged between 18 and 65 years\n* Having an isolated Zone V-VI extensor tendon injury\n* Having undergone primary treatment for the injury\n\nExclusion Criteria:\n\n* History of prior surgery on the affected extremity\n* Presence of accompanying neurological, orthopedic, rheumatologic, or metabolic disease in the affected extremity\n* Presence of flexor tendon injury\n* Presence of fractures of the metacarpals, carpal bones, or radius\u002Fulna\n* Presence of an open incision line\n* Delayed wound healing\n* Presence of peripheral nerve injury\n* Presence of replantation or amputation","65 Years",{"count":77,"type":21},[54],"This study aims to investigate the effects of Kinesio Taping (KT) on hand function in patients with Zone V-VI Extensor Digitorum Communis (EDC) tendon injuries following primary repair. Extensor tendon injuries in this region often lead to complications such as adhesion formation, reduced range of motion, extensor lag, and impaired hand function, despite standard rehabilitation approaches. Therefore, additional interventions that may enhance tendon gliding and neuromuscular control are of clinical interest.\n\nIn this double-blind randomized controlled trial, patients will be assigned to either a KT group or a sham taping control group. Both groups will receive a standardized postoperative rehabilitation program, while the intervention group will additionally receive KT applications between postoperative weeks 6 and 12. Outcome measures, including range of motion, grip and pinch strength, and functional hand performance, will be assessed at 12 and 24 weeks.\n\nThe study seeks to determine whether KT provides additional benefits beyond conventional rehabilitation in improving functional recovery after extensor tendon injuries, addressing an important gap in the current literature.",[153,154],"Extensor Tendons of Finger Anomalies","Tendon Injuries",[156,157,158],"Extensor tendon","Functional recovery","Extensor lag","2026-04-28",{"date":161,"type":31},"2026-05-05",{"date":163,"type":21},"2026-05-07",{"date":165,"type":21},"2027-06-07",{"name":37,"class":38},{"id":168,"slug":169,"hasResults":12,"nctId":170,"briefTitle":171,"officialTitle":172,"acronym":4,"eligibilityCriteria":173,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":148,"enrollmentInfo":174,"targetDuration":4,"studyType":52,"phases":176,"briefSummary":177,"conditions":178,"keywords":182,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":187,"lastUpdatePostDateStruct":188,"startDateStruct":190,"completionDateStruct":192,"leadSponsor":194,"locationsCount":4},"100633885","emg-triggered-electrical-stimulation-after-medianulnar-nerve-repairs-100633885","NCT07532499","EMG-Triggered Electrical Stimulation After Median\u002FUlnar Nerve Repairs","The Impact of EMG-Triggered Electrical Stimulation of Extensor Muscles on Functional Status Following Median and\u002For Ulnar Nerve Repairs: A Single-Blind, Randomized Controlled Study","Inclusion Criteria:\n\n* Intact communication skills\n* No prior history of neurological, orthopedic, rheumatologic, or metabolic diseases affecting the involved extremity\n\nExclusion Criteria:\n\n* Presence of concomitant central nervous system involvement\n* Pregnancy\n* Patients with cardiac pacemakers\n* Patients with cardiac arrhythmias\n* Patients with epilepsy",{"count":175,"type":21},26,[54],"Immobilization following median and\u002For ulnar nerve repairs results in strength loss in the wrist and finger extensor muscles. Given the critical importance of wrist extension for functional grip, this condition significantly restricts hand functions. Therefore, this study aims to investigate the effects of EMG-triggered electrical stimulation applied to the wrist and finger extensors, in addition to conventional physiotherapy, on functional outcomes in patients undergoing median and\u002For ulnar nerve repair, with the objective of restoring extensor muscle weakness induced by immobilization.",[179,180,181],"Peripheral Nerve Injuries","Median Nerve Injury","Ulnar Nerve Injury",[183,184,185,186],"peripheral nerve injuries","EMG-triggered electrical stimulation","physiotherapy","functional recovery","2026-04-13",{"date":189,"type":31},"2026-04-16",{"date":191,"type":21},"2026-04-30",{"date":193,"type":21},"2027-11-30",{"name":37,"class":38},{"id":196,"slug":197,"hasResults":12,"nctId":198,"briefTitle":199,"officialTitle":200,"acronym":4,"eligibilityCriteria":201,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":148,"enrollmentInfo":202,"targetDuration":204,"studyType":23,"phases":4,"briefSummary":205,"conditions":206,"keywords":209,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":187,"lastUpdatePostDateStruct":213,"startDateStruct":215,"completionDateStruct":217,"leadSponsor":219,"locationsCount":39},"100622798","perceived-ability-and-hand-function-100622798","NCT07388303","Perceived Ability and Hand Function","The Relationship Between Perceived Manual Ability and Functional Measurements in Patients With Hand-Forearm Injuries","Inclusion Criteria:\n\n* Having sustained a hand and\u002For forearm injury and\u002For having undergone surgery related to this injury.\n* Being voluntary to participate in the study.\n\nExclusion Criteria:\n\n* Patients with concomitant central nervous system involvement.\n* Patients with a history of previous injury to the same extremity.\n* Patients with rheumatological disorders.",{"count":203,"type":21},34,"12 Weeks","Patient-reported outcome measures, which are subjective by nature, need to be correlated with clinician-administered professional measurements as a further step toward expanding their clinical utility. Therefore, this study aimed to investigate the relationship between perceived manual dexterity and functional measurements in patients with hand-forearm injuries.",[207,208],"Hand Injuries","Forearm Injuries",[210,211,212],"hand forearm injuries","perceived manual ability","functional measurements",{"date":214,"type":31},"2026-04-14",{"date":216,"type":31},"2025-01-06",{"date":218,"type":21},"2026-05-31",{"name":37,"class":38},{"id":221,"slug":222,"hasResults":12,"nctId":223,"briefTitle":224,"officialTitle":224,"acronym":4,"eligibilityCriteria":225,"healthyVolunteers":48,"sex":17,"minAge":148,"maxAge":4,"enrollmentInfo":226,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":228,"conditions":229,"keywords":4,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":231,"lastUpdatePostDateStruct":232,"startDateStruct":234,"completionDateStruct":236,"leadSponsor":238,"locationsCount":39},"100632930","predictors-of-climate-change-health-literacy-in-older-individuals-100632930","NCT07520084","Predictors of Climate Change Health Literacy in Older Individuals","Inclusion Criteria:- Being 65 years of age or older\n\n* Volunteering to participate in the study\n* Inclusion of elderly individuals who score 6 or higher on the Hodkinson Mental Test.\n\nExclusion Criteria:- older adults who cannot be contacted due to reasons such as Alzheimer's disease, dementia, or psychosis\n\n* Having another chronic illness that may cause pain (rheumatic diseases, hemiplegia, multiple sclerosis, diabetes, etc.)\n* Having a neurological disease (hemiplegia, Parkinson's, multiple sclerosis, vertigo, epilepsy, etc.)\n* Being blind\n* Having an orthopedic, neurological, or intellectual disability",{"count":227,"type":21},159,"The aim of this study is to identify predictors of climate change health literacy in older adults.",[230],"Older Adults (65 Years and Older)","2026-04-02",{"date":233,"type":31},"2026-04-09",{"date":235,"type":31},"2026-03-25",{"date":237,"type":21},"2026-09-15",{"name":37,"class":38},{"id":240,"slug":241,"hasResults":12,"nctId":242,"briefTitle":243,"officialTitle":243,"acronym":244,"eligibilityCriteria":245,"healthyVolunteers":12,"sex":17,"minAge":246,"maxAge":247,"enrollmentInfo":248,"targetDuration":4,"studyType":52,"phases":250,"briefSummary":251,"conditions":252,"keywords":256,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":262,"lastUpdatePostDateStruct":263,"startDateStruct":265,"completionDateStruct":267,"leadSponsor":268,"locationsCount":4},"100629327","comparison-of-platelet-rich-plasma-and-activated-cytokine-rich-serum-injection-treatments-in-patients-with-knee-osteoarthritis-koa-prp-acs-100629327","NCT07473232","Comparison of Platelet-rich Plasma and Activated Cytokine-rich Serum Injection Treatments in Patients With Knee Osteoarthritis. (KOA PRP ACS)","KOA PRP ACS","Inclusion Criteria:\n\n1. Diagnosis of knee osteoarthritis according to ACR criteria at least 6 months ago.\n2. Being between grade 1-2 according to the Kellgren-Lawrence radiological classification.\n3. Not having had PRP injection in the last year.\n4. Knee pain ≥ 5 according to the visual pain scale.\n\nExclusion Criteria:\n\n1. Those with significant neurological or cardiovascular disorders.\n2. Those with active thrombovascular disease.\n3. Those with joint or skin infections.\n4. Those who have recently had an infectious disease.\n5. Those infected with Hepatitis B, C, and HIV.\n6. Those who have received intra-articular knee injections (hyaluronic acid, PRP, corticosteroids, and others) within the last year.\n7. Those who use oral corticosteroids.\n8. Those who have used NSAIDs within the last week.\n9. Those who have used anti-platelet or anti-aggregant drugs within the last week.\n10. Those with coagulation disorders.\n11. Those with hemoglobin \\\u003C10 g\u002Fdl and platelet count \\\u003C100,000\n12. Those with cancer.\n13. Pregnant or breastfeeding women, drug addicts.\n14. Those scheduled for knee surgery or arthroscopy, or those who have undergone knee surgery or arthroscopy.\n15. Those with diseases causing secondary osteoarthritis:\n\n    1. post-traumatic,\n    2. congenital or developmental diseases\n\n       1. Local diseases (leg length discrepancy, varus, valgus deformities, hypermobility syndromes, scoliosis)\n       2. Generalized diseases (Bone dysplasias, Metabolic disorders (hemochromatosis, ochronosis, Gaucher disease, hemoglobinopathy, Ehlers-Danlos disease))\n    3. Calcium storage diseases (calcium pyrophosphate storage disease, etc.)\n    4. Other bone and joint diseases (avascular necrosis, rheumatoid arthritis, gouty arthritis, septic arthritis, Paget's disease, osteoporosis, osteochondritis)\n    5. Other diseases\n\n       1. Endocrine diseases (Diabetes mellitus, acromegaly, hypothyroidism, hyperthyroidism)\n       2. Neuropathic arthropathy (Charcot joint)\n       3. Other (Frost, Kashin-Beck disease, Caisson disease) -","40 Years","80 Years",{"count":249,"type":21},60,[54],"The effects of single dose injection of platelet rich plasma or conditioned serum in the knee joint in patients with knee osteoarthritis will be compared",[253,254,255],"Knee Arthritis Osteoarthritis","Platelet Rich Plasma Injection","Conditioned Serum",[257,258,259,260,261],"knee osteoarthritis","platelet rich plasma injection","conditioned serum injection","inflammation","cartilage","2026-03-16",{"date":264,"type":31},"2026-03-19",{"date":266,"type":21},"2026-04-01",{"date":62,"type":21},{"name":37,"class":38},{"id":270,"slug":271,"hasResults":12,"nctId":272,"briefTitle":273,"officialTitle":274,"acronym":4,"eligibilityCriteria":275,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":148,"enrollmentInfo":276,"targetDuration":277,"studyType":23,"phases":4,"briefSummary":278,"conditions":279,"keywords":283,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":288,"lastUpdatePostDateStruct":289,"startDateStruct":291,"completionDateStruct":293,"leadSponsor":295,"locationsCount":296},"100615353","the-investigation-of-kinesiophobia-in-conservative-distal-radius-fractures-100615353","NCT07291505","The Investigation of Kinesiophobia in Conservative Distal Radius Fractures","Investigation of the Predictability of Kinesiophobia on Functional Outcomes in Conservatively Treated Distal Radius Fractures","Inclusion Criteria:\n\n* Having been treated conservatively with an isolated distal radius fracture diagnosis,\n* Having a cognitive level that allows one to understand assessment methods and apply instructions.\n\nExclusion Criteria:\n\n* Comorbid musculoskeletal-neurovascular injuries\n* Bilateral injuries",{"count":203,"type":21},"18 Weeks","This study aimed to investigate the predictability of kinesiophobia on functional outcomes in conservatively treated patients with distal radius fractures. For this purpose, patients' level of kinesiophobia will be assessed using the Tampa Kinesiophobia Scale. To assess the functional status of patients, joint range of motion and upper extremity weight bearing measurements will be performed. Patients' functionality will be additionally assessed with the Patient Rated Wrist Evaluation Questionnaire.",[280,281,282],"Distal Radius Fracture","Kinesiophobia","Functional Status",[284,285,286,287],"Tampa Scale of Kinesiophobia","distal radius fracture","wrist function","upper extremity weight bearing","2026-03-09",{"date":290,"type":31},"2026-03-10",{"date":292,"type":31},"2026-02-02",{"date":294,"type":21},"2026-12-30",{"name":37,"class":38},2,{"id":298,"slug":299,"hasResults":12,"nctId":300,"briefTitle":301,"officialTitle":302,"acronym":4,"eligibilityCriteria":303,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":148,"enrollmentInfo":304,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":306,"conditions":307,"keywords":309,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":288,"lastUpdatePostDateStruct":312,"startDateStruct":314,"completionDateStruct":316,"leadSponsor":318,"locationsCount":296},"100615352","health-literacy-level-and-functional-outcomes-in-patients-with-hand-and-forearm-injuries-100615352","NCT07291492","Health Literacy Level and Functional Outcomes in Patients With Hand and Forearm Injuries","Examining the Relationship Between Health Literacy Level and Functional Outcomes in Patients With Hand and Forearm Injuries","Inclusion Criteria:\n\n* Aged 18-65 years\n* Voluntarily agreed to participate\n* Presented with hand and\u002For forearm injuries\n\nExclusion Criteria:\n\n* Concomitant shoulder or elbow injuries\n* History of surgery due to neurological, rheumatological, or metabolic conditions affecting the entire upper extremity\n* Employment in a health-related profession",{"count":305,"type":21},117,"The aim of this study is to examine the association between health literacy, patient-reported outcome measures, and grip strength in a cohort of patients with hand injuries.",[207,308],"Forearm Fractures",[310,311],"Health Literacy","Functional Outcomes",{"date":313,"type":31},"2026-03-11",{"date":315,"type":31},"2026-01-15",{"date":317,"type":21},"2026-03-23",{"name":37,"class":38},{"id":320,"slug":321,"hasResults":12,"nctId":322,"briefTitle":323,"officialTitle":324,"acronym":4,"eligibilityCriteria":325,"healthyVolunteers":12,"sex":75,"minAge":18,"maxAge":148,"enrollmentInfo":326,"targetDuration":4,"studyType":52,"phases":327,"briefSummary":328,"conditions":329,"keywords":332,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":336,"lastUpdatePostDateStruct":337,"startDateStruct":339,"completionDateStruct":341,"leadSponsor":343,"locationsCount":39},"100604786","comparison-of-ipc-therapy-as-an-alternative-or-an-adjunct-to-mld-within-cdt-for-bcrl-100604786","NCT07154043","Comparison of IPC Therapy as an Alternative or an Adjunct to MLD Within CDT for BCRL","Comparison of Intermittent Pneumatic Compression Therapy as an Alternative or an Adjunct to Manual Lymphatic Drainage Within Complete Decongestive Therapy for Breast Cancer-Related Lymphedema","Inclusion Criteria:\n\n* Female gender\n* Patients aged 18-65 years\n* Having a history of unilateral mastectomy and lymph node dissection at least one year ago due to breast cancer diagnosis.\n* Having unilateral breast cancer-related upper extremity lymphedema (\\>20% volume difference between the two upper extremities or \\>2 cm difference in circumference at any measured point) according to the diagnostic criteria of the International Society of Lymphology (Committee 2023) for at least six months.\n* Not having received lymphedema treatment or exercise therapy for the last six months\n* Completing breast cancer primary treatment at least 6 months ago (except hormone therapy\u002Faromatase inhibitors)\n\nExclusion Criteria:\n\n* Bilateral breast cancer\n* Bilateral axillary lymph node dissection\n* Metastatic breast cancer\n* Receiving ongoing radiotherapy or chemotherapy\n* Primary or bilateral lymphedema\n* Having active cancer\n* Presence of stage 3 lymphedema\n* Uncontrolled serious systemic disease (cardiopulmonary diseases, arterial or venous diseases, renal dysfunction, uncontrolled hypertension or hypotension, cardiac arrhythmia, scleroderma, Sudek's atrophy).\n* Current or recent (within the last 3 months) infection (cellulitis, lymphangitis) or deep venous thrombosis\n* Presence of open wounds\n* Using medications that may affect body fluid and electrolyte balance (diuretics, etc.).\n* Individuals with serious mental and sensory problems\n* Being pregnant\n* Body mass index \\>40 kg\u002Fm2",{"count":20,"type":21},[54],"Breast cancer is the most common cancer among women worldwide and lymphedema is one of its most significant complications. Breast cancer-related lymphedema (BCRL) may develop shortly after treatment or even years later, causing physical and psychological burden, functional impairment, and reduced quality of life. Complete decongestive therapy (CDT), which includes manual lymph drainage (MLD), compression, skin care, and exercise, is the standard approach. Intermittent pneumatic compression (IPC) has been proposed as an additional option, and current consensus reports emphasize the need for studies evaluating IPC in combination with MLD.\n\nPrevious studies comparing IPC and MLD, either alone or in combination, have shown inconsistent results. Some reported no significant difference between treatment groups, while others suggested additional benefits of IPC, particularly in reducing limb heaviness and tension. However, there is still insufficient evidence to clarify the exact role of IPC within CDT.\n\nThe aim of this study is to investigate the acute effects of using IPC instead of MLD, or in combination with MLD, on arm circumference, arm volume, shoulder range of motion, and quality of life in patients with BCRL.",[330,331],"Breast Cancer-Related Lymphedema","BCRL",[330,333,334,335],"Manual Lymph Drainage","Intermittent Pneumatic Compression","Complete Decongestive Therapy","2026-03-03",{"date":338,"type":31},"2026-03-04",{"date":340,"type":31},"2025-09-15",{"date":342,"type":21},"2026-12-01",{"name":37,"class":38},{"id":345,"slug":346,"hasResults":12,"nctId":347,"briefTitle":348,"officialTitle":349,"acronym":4,"eligibilityCriteria":350,"healthyVolunteers":48,"sex":17,"minAge":4,"maxAge":4,"enrollmentInfo":351,"targetDuration":4,"studyType":52,"phases":353,"briefSummary":354,"conditions":355,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":360,"lastUpdatePostDateStruct":361,"startDateStruct":363,"completionDateStruct":365,"leadSponsor":367,"locationsCount":4},"100624126","the-effect-of-the-excellence-model-based-clinical-practice-preparation-program-on-students-100624126","NCT07405580","The Effect of the Excellence Model-Based Clinical Practice Preparation Program on Students","The Effect of a Preparation Program for Clinical Practice Based on the Excellence Model on Students' Readiness, Excellence, Clinical Comfort, and Anxiety Levels: A Randomized Controlled Trial","Inclusion criteria:\n\n* Being a nursing student,\n* Taking the Child Health and Nursing course for the first time,\n* Attending the course,\n* Not having previously taken pediatric nursing readiness training,\n* Agreeing to participate in the study voluntarily.\n\nExclusion criteria:\n\n* The student's refusal to participate in the study,\n* Withdrawal from the study before completing all stages of the research.",{"count":352,"type":21},50,[54],"Objective: This study was designed to develop a clinical practice preparation program based on the Pediatric Nursing Excellence Model for undergraduate nursing students and to evaluate the program's effect on students' readiness, clinical comfort and anxiety, and levels of excellence.\n\nMethod: This study is a pretest-posttest randomized controlled experimental study. The research is planned to be conducted with nursing students taking the Pediatric Health and Disease Nursing course. The study groups will consist of students who go out for clinical practice within the scope of this course. In the power analysis performed with the G\\*Power 3.1.9.7 program, the sample size was found to be 25 for the experimental group and 25 for the control group, for a total of 50. Research data will be collected using a questionnaire. The questionnaire consists of four sections containing the following questions: \"Student Descriptive Characteristics Information Form,\" \"Nursing Students' Readiness for Clinical Practice Scale,\" \"Pediatric Nursing Students' Clinical Comfort and Anxiety Instrument,\" and \"Pediatric Nursing Excellence (PHM) Model Questionnaire.\" In the study, students in the experimental group will receive routine orientation training and a clinical practice readiness program based on the excellence model. Students in the control group will only receive routine orientation training. Data analysis will be performed using the SPSS 20.0 software package.",[356,357,358,359],"Clinical Comfort and Worry","Readiness Levels for Clinical Practice","Pediatric Nursing Excellence Level","Nursing Student","2026-02-17",{"date":362,"type":31},"2026-02-19",{"date":364,"type":21},"2026-02-16",{"date":366,"type":21},"2027-06-30",{"name":37,"class":38},{"id":369,"slug":370,"hasResults":12,"nctId":371,"briefTitle":372,"officialTitle":373,"acronym":4,"eligibilityCriteria":374,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":148,"enrollmentInfo":375,"targetDuration":377,"studyType":23,"phases":4,"briefSummary":378,"conditions":379,"keywords":381,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":386,"lastUpdatePostDateStruct":387,"startDateStruct":389,"completionDateStruct":391,"leadSponsor":393,"locationsCount":39},"100622799","functional-improvement-and-fine-dexterity-in-thumb-tendon-injuries-100622799","NCT07388316","Functional Improvement and Fine Dexterity in Thumb Tendon Injuries","Investigation of the Relationship Between Functional Improvement and Changes in Fine Manual Dexterity in Isolated Thumb Tendon Injuries","Inclusion Criteria:\n\n* No history of neurological, orthopaedic, rheumatological, metabolic disease or surgery in the relevant extremity\n\nExclusion Criteria:\n\n* Comorbid musculoskeletal-neurovascular injuries",{"count":376,"type":21},52,"24 Weeks","Considering the thumb's contribution to fine dexterity and precision grip, this study aims to evaluate fine manual dexterity alongside functional outcomes following isolated thumb tendon injuries, and to examine the relationship between postoperative functional improvement and changes in fine manual dexterity.",[380,154],"Thumb Injury",[382,383,384,385],"functional status","fine dexterity","thumb","tendon injury","2026-02-04",{"date":388,"type":31},"2026-02-06",{"date":390,"type":21},"2026-02-26",{"date":392,"type":21},"2027-03-01",{"name":37,"class":38},{"id":395,"slug":396,"hasResults":12,"nctId":397,"briefTitle":398,"officialTitle":399,"acronym":400,"eligibilityCriteria":401,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":148,"enrollmentInfo":402,"targetDuration":4,"studyType":52,"phases":404,"briefSummary":405,"conditions":406,"keywords":408,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":386,"lastUpdatePostDateStruct":413,"startDateStruct":414,"completionDateStruct":416,"leadSponsor":417,"locationsCount":39},"100603149","the-effect-of-eswt-added-to-conservative-treatment-on-pain-disability-and-ultrasonographic-outcomes-in-chronic-low-back-pain-100603149","NCT07132762","The Effect of ESWT Added to Conservative Treatment on Pain, Disability, and Ultrasonographic Outcomes in Chronic Low Back Pain","The Effect of Extracorporeal Shock Wave Therapy (ESWT) Added to Conservative Treatment on Pain, Disability, and Ultrasonographic Outcomes in Chronic Low Back Pain: A Randomized Controlled Trial","ESWT","Inclusion Criteria:\n\n* Age ≥ 18 years\n* Non-specific low back pain lasting more than three months\n\nExclusion Criteria:\n\n* Specific lumbar spine diseases (radicular pain, spinal stenosis, infection)\n* History of trauma, fracture, surgery, or presence of scar tissue in the lumbar region\n* Presence of a disease that may affect muscle stiffness, such as collagen tissue disorders, hemiplegia, multiple sclerosis, or myopathies\n* Malignancy, pregnancy, severe hypertension\n* Coagulopathy, chronic heart disease\n* Ankylosing spondylitis\n* Diseases that may initially affect lumbar mobility and pain, such as leg length discrepancy, hip prosthesis, or scoliosis",{"count":403,"type":21},44,[54],"Chronic low back pain (CLBP) is a major public health concern worldwide, leading to reduced quality of life and significant work loss. It is defined as pain lasting more than 12 weeks between the lumbar and sacral spinal segments. The global prevalence of CLBP ranges from 13.1% to 20.3%, and the number of affected individuals has increased from 370 million in 1990 to 570 million in 2017.\n\nCore muscles, including the multifidus, erector spinae, transversus abdominis, psoas major, and quadratus lumborum, play a key role in spinal stabilization. In patients with CLBP, dysfunction and loss of synergy among these muscles can compromise spinal balance. Prolonged poor posture can reduce the strength and endurance of the lumbar erector spinae, multifidus, and transversus abdominis, leading patients to compensate by overusing the erector spinae, rectus abdominis, and oblique abdominal muscles. This compensation is considered one of the primary contributors to chronic low back pain.\n\nThese deep core muscles can be objectively evaluated using ultrasonography (USG), a non-invasive, inexpensive, and accessible imaging method. Strain elastography, a quantitative ultrasonographic technique, is increasingly used to assess tissue stiffness and monitor structural changes in muscle over time.\n\nConventional treatments for CLBP include pharmacotherapy, exercise, and physical therapy. In recent years, extracorporeal shock wave therapy (ESWT) has emerged as a non-invasive, easily applicable, and low-risk treatment method. ESWT is widely used in various musculoskeletal conditions such as lateral epicondylitis, patellar tendinopathy, and calcific tendinitis of the shoulder. Studies have shown that ESWT provides pain relief and functional improvement in patients with CLBP through its angiogenic, anti-inflammatory, analgesic, and tissue-regenerative effects.\n\nSeveral studies have demonstrated the positive impact of ESWT on pain reduction and functional recovery in CLBP. A recent meta-analysis reported that ESWT significantly reduces pain in CLBP patients and may be superior to other conservative treatments. Yue et al. (2021) highlighted the short-term benefits of ESWT in reducing pain and disability, while also emphasizing the need for well-designed randomized controlled trials (RCTs) to establish high-quality evidence. Similarly, Wu et al. (2023) underscored the necessity of including objective outcomes in future RCTs to better evaluate the efficacy of ESWT.\n\nAlthough numerous studies have assessed the effects of ESWT on pain, disability, and functional outcomes in CLBP, to date, no study has objectively evaluated its effectiveness using ultrasonographic strain elastography focusing on the elasticity and stiffness of core muscles.\n\nThis study aims to be one of the first to assess the long-term effects of ESWT using objective measures. Its contribution to the literature lies in evaluating the efficacy of ESWT, when added to conventional physical therapy, through long-term monitoring with ultrasonographic strain elastography in patients with CLBP.",[407],"Chronic Low Back Pain",[409,410,411,412],"Extracorporeal Shockwave Therapy treatment (ESWT)","Elastography","physical therapy","chronic low back pain",{"date":388,"type":31},{"date":415,"type":31},"2025-10-10",{"date":237,"type":21},{"name":37,"class":38},{"id":419,"slug":420,"hasResults":12,"nctId":421,"briefTitle":422,"officialTitle":423,"acronym":4,"eligibilityCriteria":424,"healthyVolunteers":12,"sex":17,"minAge":425,"maxAge":4,"enrollmentInfo":426,"targetDuration":204,"studyType":23,"phases":4,"briefSummary":427,"conditions":428,"keywords":432,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":437,"lastUpdatePostDateStruct":438,"startDateStruct":440,"completionDateStruct":442,"leadSponsor":443,"locationsCount":39},"100622100","the-cognitive-functional-relationship-in-geriatric-hand-forearm-injuries-100622100","NCT07379229","The Cognitive-Functional Relationship in Geriatric Hand-Forearm Injuries","Investigation of the Relationship Between Cognitive and Functional Status in Geriatric Patients With Hand-Forearm Injuries","Inclusion Criteria:\n\n* Being over 65 years of age\n* Having sufficient communication skills and auditory-visual abilities to complete cognitive tests\n\nExclusion Criteria:\n\n* Inability to perform functional tests due to active wounds, open fractures, or severe pain\n* Inability to administer cognitive tests due to aphasia or severe hearing or visual impairment","66 Years",{"count":203,"type":21},"Considering the complex structure of hand-forearm injuries and the long rehabilitation process, it is important to investigate factors associated with recovery in geriatric individuals. Therefore, this study aimed to examine the relationship between cognitive status and functional outcomes in geriatric individuals with hand-forearm injuries.",[429,430,431,207],"Geriatric Population","Cognitive Ability","Functional Abilities",[433,434,435,436],"geriatric population","hand Injuries","functional outcome","cognitive function","2026-01-30",{"date":439,"type":31},"2026-02-03",{"date":441,"type":21},"2026-02-23",{"date":294,"type":21},{"name":37,"class":38},{"id":445,"slug":446,"hasResults":12,"nctId":447,"briefTitle":448,"officialTitle":449,"acronym":4,"eligibilityCriteria":450,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":246,"enrollmentInfo":451,"targetDuration":4,"studyType":52,"phases":453,"briefSummary":454,"conditions":455,"keywords":457,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":460,"lastUpdatePostDateStruct":461,"startDateStruct":462,"completionDateStruct":463,"leadSponsor":464,"locationsCount":39},"100622316","whole-body-vibration-in-patients-with-patellofemoral-pain-syndrome-100622316","NCT07382037","Whole-Body Vibration in Patients With Patellofemoral Pain Syndrome","Efficacy of Whole-Body Vibration in Patients With Patellofemoral Pain Syndrome: A Prospective, Randomized, Double-Blind, Placebo-Controlled Clinical Trial","Inclusion Criteria:\n\n* Aged between 18 and 40 years,\n* Diagnosed with unilateral Patellofemoral Pain Syndrome (PFPS),\n* Reporting anterior knee pain or pain behind the patella in at least two of the following activities:\n\nascending stairs, jumping, running, squatting, kneeling, prolonged sitting,\n\n\\- Positive results in at least two of the following clinical tests: Eccentric step-down test, Patellar border tenderness test, Patellar grind (Clarke's) or apprehension test,\n\n* Ability to understand the procedures, potential benefits, and possible adverse effects,\n* Willingness to participate in the treatment program.\n\nExclusion Criteria:\n\n* Severe injury or pathological changes in knee structures (e.g., ligaments, menisci, patellar tendons, iliotibial bands, joint capsules, or plicae),\n* History of significant trauma or surgery involving the knee or lower extremity,\n* History of patellar dislocation or subluxation,\n* Diagnosis of Osgood-Schlatter disease or Sinding-Larsen-Johansson syndrome,\n* Joint effusion in the knee, or presence of redness, swelling, or increased warmth on physical examination,\n* Serious systemic conditions, including cardiovascular diseases, tumors, gallstones or kidney stones, severe disc or spinal lesions, pacemaker implantation, epilepsy, recent fractures or surgeries, or acute arthritis,\n* Pregnancy.",{"count":452,"type":21},40,[54],"Patellofemoral Pain Syndrome (PFPS), or anterior knee pain, is one of the most common disorders affecting the lower extremities.\n\nCurrently, there is no established \"gold standard\" treatment for PFPS. However, various interventions-including strengthening of the hip and knee muscles (e.g., hip abductors, external rotators, and knee extensors), taping, bracing, foot orthoses, manual therapy, acupuncture, blood flow restriction training, and conventional physical agents (e.g., ultrasound, cryotherapy, neuromuscular electrical stimulation, laser therapy, electromyographic biofeedback, etc.)-have been reported to provide meaningful clinical benefits. Strengthening of the hip and knee muscles alone has been shown to improve both pain and function in the short, medium, and long term. In recent high-quality studies, hip and knee muscle strengthening has been recognized as an effective \"classical\" treatment approach for PFPS. Regarding the mechanism of pain relief, previous research suggests that strengthening these muscles may alleviate pain by stabilizing patellar motion and\u002For reducing pressure on the patellofemoral joint.\n\nSimilar to traditional resistance training, whole-body vibration (WBV) training is an alternative method for muscle strengthening. WBV platforms can generate vertical vibrations that stimulate tonic vibration reflexes through muscle spindles, thereby activating homonymous alpha motor neurons and inducing reflex muscle contractions. As a result, increased motor unit recruitment enhances the excitability of muscle spindles, leading to improved muscle strength. Additionally, WBV training can improve muscle balance, strength, and function. Therefore, combining WBV with hip and knee strengthening exercises may represent a more effective treatment strategy for PFPS. The aim of this study is to evaluate whether the combination of WBV and hip-knee muscle strengthening is more effective in reducing pain and improving function than hip-knee strengthening alone.",[456],"Patellofemoral Pain, PFP",[458,459],"whole body vibration","knee","2026-01-25",{"date":292,"type":31},{"date":315,"type":21},{"date":139,"type":21},{"name":37,"class":38},{"id":466,"slug":467,"hasResults":12,"nctId":468,"briefTitle":469,"officialTitle":469,"acronym":4,"eligibilityCriteria":470,"healthyVolunteers":12,"sex":75,"minAge":18,"maxAge":4,"enrollmentInfo":471,"targetDuration":4,"studyType":52,"phases":473,"briefSummary":474,"conditions":475,"keywords":477,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":482,"lastUpdatePostDateStruct":483,"startDateStruct":485,"completionDateStruct":487,"leadSponsor":489,"locationsCount":39},"100621153","comparison-of-the-efficacy-of-perineal-and-intravaginal-electrical-stimulation-in-women-with-idiopathic-overactive-bladder-100621153","NCT07366918","Comparison of the Efficacy of Perineal and Intravaginal Electrical Stimulation in Women With Idiopathic Overactive Bladder","Inclusion Criteria:\n\n* Women over the age of 18 with a clinical diagnosis of idiopathic OAB\n* Intolerant or unresponsive to antimuscarinic or oral β3 adrenoceptor agonist (mirabegron) medications and not using them for at least 4 weeks\n* Ability to understand the procedures, advantages, and potential side effects\n* Ability to provide written, informed consent\n* Pelvic floor muscle (PFM) strength of 3\u002F5 or higher (modified Oxford scale, minimum: 0 - maximum: 5)\n\nExclusion Criteria:\n\n* Women with pure stress urinary incontinence\n* History of conservative treatment for OAB within the last 6 months (MI, IVES, perineal ES, etc.)\n* Pregnant or planning to become pregnant at the time of the study\n* Diagnosis of vaginal infection, urinary tract infection, or cancer\n* Women with urinary incontinence within the last 3 months Those who have undergone urogynecological surgery\n* Those with genital area disorders that may preclude the use of a vaginal probe or perineal electrode\n* Those diagnosed with stage 2 or higher according to the Pelvic Organ Prolapse Assessment (POP-Q)\n* Those with a pacemaker or implanted defibrillator\n* Those with neurogenic bladder or a history of neurological disease\n* Those with a urine residual of more than 100 ml detected by ultrasound (using an ultrasound device)\n* Those with allergies to condoms or lubricating gels used with a vaginal probe or perineometer",{"count":472,"type":21},63,[54],"The investigators conducted a prospective, randomized double-blind, placebo-controlled study based on a placebo technique to evaluate the efficacy of IVES vs perineal ES in women with idiopathic OAB.\n\nThe main questions aimed to be answered are:\n\nIs Intravaginal Electrical Stimulation (IVES) or perineal ES more effective on clinical parameters related to incontinence and quality of life in women with idiopathic overactive bladder (OAB)? Participants (n:63) with idiopathic OAB who meet the exclusion and inclusion criteria will be divided into 3 groups using a randomization table. The first group will receive IVES and bladder training (n:21), second group will receive perineal ES and bladder training (n:21) and third group will receive bladder training (n=21) . Measurements will be performed twice in total, before and at the end of treatment (8th week).",[476],"Urinary Bladder, Overactive",[478,479,480,481],"Idiopathic overactive bladder","Urinary incontinence","perineal electrical stimulation","Intravaginal electrical stimulation","2026-01-16",{"date":484,"type":31},"2026-01-26",{"date":486,"type":31},"2025-12-01",{"date":488,"type":21},"2027-01-01",{"name":37,"class":38},{"id":491,"slug":492,"hasResults":12,"nctId":493,"briefTitle":494,"officialTitle":495,"acronym":4,"eligibilityCriteria":496,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":148,"enrollmentInfo":497,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":499,"conditions":500,"keywords":501,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":504,"lastUpdatePostDateStruct":505,"startDateStruct":507,"completionDateStruct":508,"leadSponsor":510,"locationsCount":39},"100619205","minimal-clinically-important-difference-of-the-push-off-test-100619205","NCT07341594","Minimal Clinically Important Difference of the Push-Off Test","Determination of the Minimal Clinically Important Difference of the Push-Off Test in Distal Radius Fractures","Inclusion Criteria:\n\n* Diagnosis of distal radius fracture (DRF) and treatment with either conservative or surgical methods\n* Voluntary participation\n* Age between 18 and 65 years\n* Having a cognitive level sufficient to understand the assessment methods and follow instructions\n\nExclusion Criteria:\n\n* Presence of concomitant musculoskeletal or neurovascular injuries in the affected extremity\n* Presence of a neurological, orthopedic, rheumatologic, or metabolic condition that could affect the affected extremity",{"count":498,"type":21},109,"The aim was to determine the minimal clinically important difference of the push-off test in distal radius fractures.",[280],[285,502,503],"minimal clinically important difference","the push-off test","2026-01-06",{"date":506,"type":31},"2026-01-14",{"date":482,"type":21},{"date":509,"type":21},"2026-06-12",{"name":37,"class":38},{"id":512,"slug":513,"hasResults":12,"nctId":514,"briefTitle":515,"officialTitle":516,"acronym":4,"eligibilityCriteria":517,"healthyVolunteers":48,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":518,"targetDuration":4,"studyType":23,"phases":4,"briefSummary":520,"conditions":521,"keywords":524,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":529,"lastUpdatePostDateStruct":530,"startDateStruct":532,"completionDateStruct":533,"leadSponsor":535,"locationsCount":4},"100610540","respiratory-and-anxiety-status-of-music-students-100610540","NCT07228910","Respiratory and Anxiety Status of Music Students","Relationship Between Dysfunctional Breathing, Respiratory Patterns, and Performance Anxiety in Music Students","Inclusion Criteria:\n\n* Being a student of music department\n* Playing an instrument for at least 1 year\n* Volunteer\n\nExclusion Criteria:\n\n* Having any respiratory disease (Asthma , COPD etc.)",{"count":519,"type":21},233,"This study aims to determine the prevalence and patterns of dysfunctional breathing (DB) among music students and to investigate its relationship with music performance anxiety (MPA). Dysfunctional breathing, also known as a breathing pattern disorder, refers to maladaptive respiratory patterns not explained by medical conditions such as asthma and is associated with symptoms like hyperventilation, poor breathing control, and abnormal respiratory mechanics. Given that MPA is common among musicians and often accompanied by symptoms such as palpitations, tremor, and shortness of breath, this study explores whether DB contributes to or is influenced by performance-related anxiety in this population.",[522,523],"Dysfunctional Breathing","Breathing Patterns",[525,526,527,528],"Dysfunctional breathing","Breathing patterns","Music students","Music performance anxiety","2025-11-13",{"date":531,"type":31},"2025-11-14",{"date":486,"type":21},{"date":534,"type":21},"2026-01-31",{"name":37,"class":38},{"id":537,"slug":538,"hasResults":12,"nctId":539,"briefTitle":540,"officialTitle":541,"acronym":4,"eligibilityCriteria":542,"healthyVolunteers":12,"sex":17,"minAge":543,"maxAge":148,"enrollmentInfo":544,"targetDuration":4,"studyType":52,"phases":546,"briefSummary":547,"conditions":548,"keywords":552,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":556,"lastUpdatePostDateStruct":557,"startDateStruct":559,"completionDateStruct":561,"leadSponsor":562,"locationsCount":39},"100602153","clinical-and-ultrasonographic-evaluation-of-the-efficacy-of-extracorporeal-shock-wave-therapy-eswt-in-post-stroke-spasticity-100602153","NCT07119801","Clinical and Ultrasonographic Evaluation of the Efficacy of Extracorporeal Shock Wave Therapy (ESWT) in Post-Stroke Spasticity","Clinical and Ultrasonographic Evaluation of the Efficacy of Extracorporeal Shock Wave Therapy (ESWT) in Post-Stroke Spasticity: A Randomized Controlled Trial","Inclusion Criteria:\n\n* Age between 35 and 65 years.\n* First-ever stroke episode confirmed by MRI and\u002For CT scan.\n* Clinical diagnosis of hemiplegia.\n* More than 6 months post-stroke.\n* A Modified Ashworth Scale (MAS) score between 1 and 3 for wrist flexor spasticity.\n\nExclusion Criteria:\n\n* History of more than one stroke episode\n* Stroke onset more than ten years ago\n* Stroke onset less than 6 months ago\n* Age over 65 (to limit the effects of aging on muscle structure)\n* Contraindications for ESWT (e.g., cancer, local tumor or active infection in the treatment area, pregnancy, coagulation disorders, pacemaker or other electronic\u002Fmetallic implants)\n* Severe aphasia or serious communication problems\n* Presence of fixed contracture in the wrist\n* Patients who have received botulinum toxin or phenol nerve block injections within the last 6 months\n* Medically unstable patients (e.g., uncontrolled hypertension, diabetes mellitus, or severe cardiac, hepatic, or renal disease)","35 Years",{"count":545,"type":21},32,[54],"This research evaluate the effectiveness of Extracorporeal Shock Wave Therapy (ESWT) for treating spasticity in the wrist flexor muscles (flexor carpi ulnaris - FCU and flexor carpi radialis - FCR) of chronic stroke patients.\n\nSpasticity, a common complication after a stroke, causes muscle stiffness, pain, and functional limitation, leading to increased healthcare costs and a lower quality of life. Current treatments like medication and injections have significant drawbacks, such as side effects and high costs, creating a need for new, non-invasive, and effective methods.\n\nThe study highlights that traditional methods for assessing spasticity, like the Modified Ashworth Scale (MAS), are subjective. It proposes using objective, non-invasive ultrasound techniques-specifically strain elastography (to measure muscle stiffness) and echogenicity (to assess muscle tissue quality)-for a more reliable evaluation.\n\nThe primary goal of this research is to be the first to investigate the short- and long-term effects of ESWT on the FCR and FCU muscles using these objective ultrasound measures alongside traditional clinical scales. The findings are expected to help standardize ESWT treatment protocols and promote the use of objective ultrasound data for the management and follow-up of post-stroke spasticity.",[549,550,551],"Stroke","Spastic Hemiplegia","Extracorporal Shockwave Therapy (ESWT)",[553,554,555],"spastic hemiplegia","extracorporeal shockwave therapy","spasticity of the wrist flexors","2025-09-23",{"date":558,"type":31},"2025-09-29",{"date":560,"type":31},"2025-09-05",{"date":113,"type":21},{"name":37,"class":38},{"id":564,"slug":565,"hasResults":12,"nctId":566,"briefTitle":567,"officialTitle":568,"acronym":4,"eligibilityCriteria":569,"healthyVolunteers":48,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":570,"targetDuration":4,"studyType":52,"phases":571,"briefSummary":572,"conditions":573,"keywords":575,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":579,"lastUpdatePostDateStruct":580,"startDateStruct":582,"completionDateStruct":584,"leadSponsor":586,"locationsCount":39},"100591907","clinical-evaluation-of-two-different-surgical-techniques-with-prf-in-the-treatment-of-multiple-gingival-recessions-100591907","NCT06986525","Clinical Evaluation of Two Different Surgical Techniques With PRF in the Treatment of Multiple Gingival Recessions","A Prospective Split-Mouth Clinical Study Comparing Coronally Advanced Flap and Tunnel Techniques Combined With Platelet-Rich Fibrin in the Treatment of Multiple Gingival Recessions","Inclusion Criteria:\n\n* Age 18 years or older\n* Systemically healthy individuals\n* Presence of bilateral Miller Class I-II multiple gingival recessions\n* Good oral hygiene and willingness to follow instructions\n* Signed informed consent\n\nExclusion Criteria:\n\n* Use of tobacco or smoking\n* Pregnancy or lactation\n* Presence of systemic diseases affecting periodontal health\n* Use of medications that may affect healing (e.g., corticosteroids)\n* Periodontal surgery in the same area within the last 6 months",{"count":51,"type":21},[54],"This prospective clinical study aims to evaluate and compare the effectiveness of coronally advanced flap (CAF) and tunnel techniques, both combined with platelet-rich fibrin (PRF), in the treatment of multiple Miller Class I-II gingival recessions. Eleven participants with bilateral defects will be treated using a split-mouth design. Periodontal parameters will be assessed at baseline, 3 months, and 6 months.",[574],"Gingival Recession",[576,577,578],"gingival recessions","platelet rich fibrin","root coverage","2025-08-13",{"date":581,"type":31},"2025-08-17",{"date":583,"type":21},"2025-08-15",{"date":585,"type":21},"2026-03-15",{"name":37,"class":38},{"id":588,"slug":589,"hasResults":12,"nctId":590,"briefTitle":591,"officialTitle":591,"acronym":4,"eligibilityCriteria":592,"healthyVolunteers":12,"sex":17,"minAge":246,"maxAge":593,"enrollmentInfo":594,"targetDuration":595,"studyType":23,"phases":4,"briefSummary":596,"conditions":597,"keywords":600,"overallStatus":59,"whyStopped":4,"lastUpdateSubmitDate":604,"lastUpdatePostDateStruct":605,"startDateStruct":607,"completionDateStruct":609,"leadSponsor":611,"locationsCount":39},"100534501","the-effect-of-rf-genicular-nerve-block-applied-in-the-preoperative-period-on-fast-track-total-knee-arthroplasty-100534501","NCT06239649","The Effect of RF Genicular Nerve Block Applied in the Preoperative Period on Fast-track Total Knee Arthroplasty","Inclusion Criteria:\n\n* Being between the ages of 40 and 85,\n* Being able to understand verbal and written information given in Turkish,\n* Being able to speak and understand Turkish,\n* Being subjected to unilateral TKA surgery due to the diagnosis of Primary Knee osteoarthritis\n\nExclusion Criteria:\n\n* Patients planned for revision knee prosthesis surgery,\n* Patients previously diagnosed with psychiatric disorders,\n* Patients who have undergone major surgery on the extremity where TKA will be applied,\n* Patients with comorbid diseases such as rheumatoid arthritis or cancer,\n* Patients with a score above 3 according to the American Society of Anesthesiologists (ASA) scoring,\n* Patients with neurological diseases that cause functional disability,\n* Patients with flexion limitation of more than 45 degrees and extension limitation of more than 20 degrees,\n* Patients who have to use hypnotic or anxiolytic drugs regularly,\n* Patients with alcohol or drug addiction,\n* Patients with bleeding disorders\n* Patients with uncontrolled diabetes","85 Years",{"count":249,"type":21},"3 Months","In our study, investigators plan to compare the preoperative RF and genicular nerve ablation approach in patients who underwent TKA(Total Knee Arthroplasty) using the Fast-Track protocol in terms of meeting postoperative pain, function and early discharge criteria.",[598,599],"Knee Osteoarthritis","Knee Pain Chronic",[601,602,603],"Fast-Track Total Knee Arthroplasty","Genicular Nerve Block","Radiofrequency Ablation","2025-06-02",{"date":606,"type":31},"2025-06-04",{"date":608,"type":31},"2023-10-19",{"date":610,"type":21},"2025-06-01",{"name":37,"class":38},{"id":613,"slug":614,"hasResults":12,"nctId":615,"briefTitle":616,"officialTitle":617,"acronym":4,"eligibilityCriteria":618,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":247,"enrollmentInfo":619,"targetDuration":4,"studyType":52,"phases":620,"briefSummary":621,"conditions":622,"keywords":4,"overallStatus":27,"whyStopped":4,"lastUpdateSubmitDate":624,"lastUpdatePostDateStruct":625,"startDateStruct":627,"completionDateStruct":628,"leadSponsor":630,"locationsCount":4},"100591120","the-effects-of-cognitive-behavioral-approach-based-psychoeducation-on-caregivers-of-alzheimers-patients-100591120","NCT06976294","The Effects of Cognitive Behavioral Approach-Based Psychoeducation on Caregivers of Alzheimer's Patients","The Effect of Cognitive Behavioral Approach-Based Psychoeducation on Post-Traumatic Growth, Psychological Resilience, and Ruminative Thoughts in Primary Caregivers of Individuals Diagnosed With Alzheimer's Disease","Inclusion Criteria:\n\n* Aged 18 years or older\n* Willing to participate in the study\n* A member of the Denizli Alzheimer Association\n* At least a primary school graduate\n* Able to communicate effectively\n* Providing primary care to an individual diagnosed with Alzheimer's for at least one year\n* Providing primary care to a patient diagnosed with moderate to advanced stage Alzheimer's\n* Serving as a primary caregiver for at least six months\n\nExclusion Criteria:\n\n* Primary caregivers who have participated in any psychoeducation group\n* Caregivers who have been diagnosed with any mental health disorder",{"count":352,"type":21},[54],"Alzheimer's disease is a progressive and chronic neurocognitive disorder. Individuals who assume the role of primary caregivers and are responsible for meeting the care needs of the patient often develop serious health problems over time. It is particularly important to assess the psychological resilience of those who struggle to manage the caregiving process, to identify ruminative thoughts developed in response to negative experiences, and ultimately to determine the presence of post-traumatic growth. Cognitive Behavioral Therapy (CBT)-based psychoeducational interventions are highly effective in the holistic assessment and support of primary caregivers.",[623],"Alzheimer Disease, Posttraumatic Growth","2025-05-15",{"date":626,"type":31},"2025-05-16",{"date":340,"type":21},{"date":629,"type":21},"2025-12-31",{"name":37,"class":38},""]