[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Parc Sanitari Pere Virgili\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":134},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,46,76,105],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":34,"lastUpdatePostDateStruct":35,"startDateStruct":38,"completionDateStruct":40,"leadSponsor":42,"locationsCount":45},"100624380","evaluation-of-an-integrated-home-care-model-100624380",false,"NCT07408882","Evaluation of an Integrated Home Care Model","Integrated Home Care (ADMIT). Transforming the Model of Home Care Though Technology and Integrated Health and Social Care","ADMIT","Inclusion Criteria:\n\n* Living at home AND\n* Adjusted Morbidity Group = 3 or 4 or high risk OR Complex or Advanced frailty or chronicity OR Home health care program; AND\n* Dependent for the basic daily activities OR Social complexity (SSM-CAT positive) OR Dependency grade= 1, 2 or 3 OR Lack of social support OR Home social care program OR Living alone\n\nExclusion Criteria:\n\n* Living in a nursing home\n* Unable to make decisions about care (either by the patient or the caregiver)\n* Person with needs that exceed the coverage of the program\n* Not providing informed consent","ALL","70 Years",{"count":20,"type":21},1000,"ESTIMATED","INTERVENTIONAL",[24],"NA","The demographic shift towards a progressive aging of the population represents an unprecedented challenge for Western societies and for the sustainability of health and social systems.\n\nHypotheses: A complex, multi-component intervention based on integrated home care, facilitated by technological tools and focused on the frail person with complex needs (ADMIT Program):\n\n* Will increase at least 5% of the days spent at home compared to usual care\n* Will reduce exacerbations or health or social crisis at home\n* Will improve the quality of life and well-being of users and their informal caregiver\n* Will improve the experience of the people cared for, their caregivers and professionals in the health and social systems\n\nMain objective: To evaluate the effectiveness of the ADMIT program in increasing the % of days at home of frail elderly people compared to usual practice.\n\nSecondary objectives:\n\nTo evaluate the effectiveness of the ADMIT program compared to usual care to reduce exacerbations or situations of crisis that motivate emergency care or hospitalizations.\n\nTo evaluate the incremental cost-utility ratio of the ADMIT program in relation to usual practice, exploring different time horizons and different scenarios of population scalability.\n\nTo evaluate the experience of the people treated, their informal caregivers and professionals.\n\nTo identify the determinants of change and contextual factors of the program implementation process\n\nMethodology:\n\nHybrid evaluation model that allows evaluating the process, effectiveness, safety and cost-utility while implementing the intervention in real life. Mixed methods, typical of implementation science, will be used, with different stages: First stage: co-creation of the care model and the technological platform with the participation of users and professionals Second stage: evaluation of the process, results and experience through a pragmatic randomized controlled trial with a batched stepped wedge design and comparison with a parallel \"external\" control group, matched using propensity score techniques.\n\nApplicability and Relevance: The ADMIT program is aligned with the current trend and the shared interest of evolving towards integrated social and health care, keeping people with complex needs in their homes for as long as possible and with the best possible quality of life. The ADMIT project is an implementation project supported by the Catalan Health Department and the Integrated Care Agency. The technological platform that will be co-created and piloted is expected to be adopted by Catalan Health Department for its scaling up in the territory.",[27],"Older Adults (70 or More) Living at Home With Health and Social Complexity",[29,30,31,32],"integrated care","implementation science","mixed models","hybrid design","RECRUITING","2026-02-13",{"date":36,"type":37},"2026-02-18","ACTUAL",{"date":39,"type":37},"2025-05-15",{"date":41,"type":21},"2026-10-31",{"name":43,"class":44},"Parc Sanitari Pere Virgili","OTHER",8,{"id":47,"slug":48,"hasResults":11,"nctId":49,"briefTitle":50,"officialTitle":51,"acronym":52,"eligibilityCriteria":53,"healthyVolunteers":11,"sex":17,"minAge":54,"maxAge":55,"enrollmentInfo":56,"targetDuration":4,"studyType":22,"phases":58,"briefSummary":59,"conditions":60,"keywords":62,"overallStatus":66,"whyStopped":4,"lastUpdateSubmitDate":67,"lastUpdatePostDateStruct":68,"startDateStruct":70,"completionDateStruct":72,"leadSponsor":74,"locationsCount":75},"100608932","lifestyle-intervention-for-type-2-diabetes-in-primary-care-credoenap-100608932","NCT07207980","Lifestyle Intervention for Type 2 Diabetes in Primary Care (CREDOenAP)","Lifestyle Intervention Clinical Trial for the Remission of Type 2 Diabetes Mellitus in Primary Care (CREDOenAP)","CREDOenAP","Inclusion Criteria:\n\n1. Signed informed consent.\n2. Men and women aged 18-80 years, inclusive.\n3. Confirmed diagnosis of T2DM according to recognized diagnostic criteria\n4. Most recent recorded hemoglobin A1c (HbA1c) \\> 6.5%.\n5. Body Mass Index (BMI) greater than 27 kg\u002Fm².\n\nExclusion Criteria:\n\n1. Failure to meet the diagnostic criteria for T2DM in the screening laboratory tests.\n2. Being dependent for basic activities of daily living (Barthel score ≤ 90 points).\n3. Lack of willingness to cooperate with the follow-up of the lifestyle intervention plan.\n4. Presence of serious or terminal comorbidities significantly worsening short- to medium-term prognosis (active cancer, terminal chronic diseases, myocardial infarction within the last 6 months, acute heart failure or NYHA stage ≥ III, etc.).\n5. History of ketoacidosis.\n6. Presence of criteria or potential autoimmune insulinopenia (abnormal C-peptide, anti-GAD+ antibodies, pattern of basal and\u002For glucose-stimulated hypoinsulinemia).\n7. Cognitive impairment.\n8. Weight loss exceeding 5 kg in the past 6 months.\n9. Significant changes in physical activity and\u002For dietary patterns in the past 6 months.\n10. History of eating disorders.\n11. History of substance abuse.\n12. History of severe psychiatric disorders.\n13. Pregnancy or intention to become pregnant within the study period.","18 Years","80 Years",{"count":57,"type":21},120,[24],"The purpose of this clinical trial is to determine whether an intensive lifestyle intervention can achieve remission of type 2 diabetes mellitus (T2DM) in adult patients treated in primary care. The main questions the study seeks to answer are:\n\n* What proportion of participants achieve diabetes remission after 6 months of intervention?\n* How many participants maintain remission 12 months after completing the program (18 months total)?\n\nParticipants will:\n\n* Follow a personalized dietary plan with carbohydrate restriction.\n* Engage in moderate, accessible physical activity.\n* Implement strategies to improve circadian rhythm regularity.\n* Receive psychological counseling and support.",[61],"Type 2 Diabetes Mellitus (T2DM)",[61,63,64,65],"Diabetes Remission","Lifestyle Intervention","Primary Care","NOT_YET_RECRUITING","2025-09-26",{"date":69,"type":37},"2025-10-06",{"date":71,"type":21},"2026-01-11",{"date":73,"type":21},"2028-01-11",{"name":43,"class":44},1,{"id":77,"slug":78,"hasResults":11,"nctId":79,"briefTitle":80,"officialTitle":81,"acronym":82,"eligibilityCriteria":83,"healthyVolunteers":11,"sex":17,"minAge":84,"maxAge":4,"enrollmentInfo":85,"targetDuration":4,"studyType":22,"phases":87,"briefSummary":88,"conditions":89,"keywords":92,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":97,"lastUpdatePostDateStruct":98,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":104,"locationsCount":75},"100594105","applying-a-multidisciplinary-intervention-for-drug-adequacy-in-an-intermediate-care-hospital-amida-ich-100594105","NCT07015112","Applying a Multidisciplinary Intervention for Drug Adequacy in an Intermediate Care Hospital (AMIDA-ICH)","Applying a Multidisciplinary Intervention for Drug Adequacy in a Intermediate Care Hospital (AMIDA-ICH)","AMIDA-ICH","Inclusion Criteria:\n\n* older adults (65+ years)\n* ≥ 3 or more chronic conditions requiring medical therapy\n* able to speak Spanish\n* capacity to provide informed consent or have a surrogate able to consent on their behalf\n\nExclusion Criteria:\n\n* unable to provide informed consent\n* anticipated length of hospital stay \\\u003C 72h\n* estimated life expectancy \\\u003C 3 months\n* homeless\n* already enrolled in a drug trial","65 Years",{"count":86,"type":21},300,[24],"The goal of this clinical trial is to learn if a multi-professional (conducted by geriatricians, clinical pharmacists, nurses) medication revision, centered on patients' goals and characteristics, can improve treatment adequacy in older adults admitted to an intermediate care hospital.\n\nThe main question it aims to answer is: does this approach reduce the average number of medications taken per patient?\n\nResearchers will compare this multi-professional patient-centered revision to the usual standard of care (treatment revision conducted by a clinical pharmacist) to see if the patient-centered revision works in improving treatment adequacy.\n\nParticipants admitted to an intermediate care hospital will undergo a comprehensive assessment by a geriatrician, and a medication revision (conducted by a multidisciplinary team or a clinical-pharmacist alone). They will also be asked to fulfill some questionnaires on their health status and attitudes. Any possible adverse events to the medications will be recorded at discharge. Participants will be contacted again three months after discharge to check for any readmission or death.",[90,91],"Poly Pharmacy","Frail Elderly",[93,94,95,96],"polypharmacy","frailty","adverse drug event","deprescribing","2025-06-10",{"date":99,"type":37},"2025-06-11",{"date":101,"type":37},"2024-01-04",{"date":103,"type":21},"2026-06",{"name":43,"class":44},{"id":106,"slug":107,"hasResults":11,"nctId":108,"briefTitle":109,"officialTitle":110,"acronym":111,"eligibilityCriteria":112,"healthyVolunteers":11,"sex":17,"minAge":84,"maxAge":4,"enrollmentInfo":113,"targetDuration":4,"studyType":22,"phases":115,"briefSummary":116,"conditions":117,"keywords":121,"overallStatus":33,"whyStopped":4,"lastUpdateSubmitDate":125,"lastUpdatePostDateStruct":126,"startDateStruct":128,"completionDateStruct":130,"leadSponsor":132,"locationsCount":133},"100580351","agil-barcelona-integrated-care-for-community-dwelling-frail-older-adults-100580351","NCT06836167","+AGIL Barcelona: Integrated Care for Community-Dwelling Frail Older Adults","+ AGIL Barcelona: Integrated Care for Community-Dwelling Frail Older Adults","+AGIL","Inclusion Criteria:\n\n* People aged 65 or older\n* Presenting with suggestive signs of frailty according to the Gérontopôle Frailty Screening Test (GFST).\n* Agree to participate and sign informed consent\n\nExclusion Criteria:\n\n* Requirement for hospital admission or an estimated life expectancy of less than one year.",{"count":114,"type":21},396,[24],"The goal of this clinical trial is to evaluate the effectiveness of the +AGIL Barcelona program in helping older adults improve their physical abilities and delay disability. It will also explore how to adapt and expand the program to different neighborhoods in Barcelona. The main questions it aims to answer are:\n\nDoes the +AGIL program improve physical abilities, as measured by a simple physical performance test (SPPB)? How well can the program be adapted and implemented in different community health centers? Researchers will conduct the study in three community health centers in Barcelona, following a stepped approach to gradually introduce the program at each site.\n\nParticipants will:\n\nParticipate in up to 10 weekly group exercise sessions led by a physiotherapist. Focus on strength, balance, flexibility, and endurance. Exercises will be tailored to individual needs and supported with easy-to-understand materials.\n\nReceive advice on healthy habits like eating a Mediterranean diet, improving sleep, and managing swallowing or memory issues.\n\nGet support to connect with local activities and resources to reduce loneliness and stay active, such as community centers or fitness programs.\n\nHave their medications reviewed by healthcare professionals to ensure they are appropriate and safe.\n\nThe program will be personalized based on each participant's needs. This study will provide valuable information on implementing practical programs that help older adults stay healthy and independent.",[118,119,120],"Frailty","Older Adults","Healthy Aging",[94,122,120,29,123,124],"older adults","physical performance","intrinsic capacity","2025-02-17",{"date":127,"type":37},"2025-02-20",{"date":129,"type":37},"2022-11-02",{"date":131,"type":21},"2025-07-31",{"name":43,"class":44},3,""]