[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Paris Translational Research Center for Organ Transplantation\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":114},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,4,0,[8,41,64,94],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":13,"acronym":14,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":22,"conditions":23,"keywords":25,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":29,"lastUpdatePostDateStruct":30,"startDateStruct":33,"completionDateStruct":35,"leadSponsor":37,"locationsCount":40},"100638744","perceptions-of-kidney-transplant-recipients-regarding-the-role-of-artificial-intelligence-in-medicine-100638744",false,"NCT07600541","Perceptions of Kidney Transplant Recipients Regarding the Role of Artificial Intelligence in Medicine","AITX","* Inclusion criteria\n\n  * Age ≥ 18 years\n  * Fluency in French or English\n  * Electronic consent given\n* Exclusion criteria\n\n  * Severe cognitive impairment preventing comprehension\n  * Technical inability to access the questionnaire","ALL","18 Years",{"count":19,"type":20},1000,"ESTIMATED","OBSERVATIONAL","The AITX study is an international, multicenter survey exploring how kidney transplant recipients perceive artificial intelligence (AI) in medicine and, specifically, a system that predicts graft loss risk. Through an open-ended online questionnaire distributed across transplant centers and patient associations in France and the United States, the study captures patients' expectations, concerns, and the perceived impact of AI-driven prediction on their daily lives. Responses are analyzed using large language models (LLMs) with systematic human verification. The study aims to ensure that the deployment of AI in transplantation is ethical, transparent, and patient-centered.",[24],"Kidney Transplant",[26,27],"artificial intelligence","survey","RECRUITING","2026-05-13",{"date":31,"type":32},"2026-05-20","ACTUAL",{"date":34,"type":32},"2026-04-15",{"date":36,"type":20},"2026-12-30",{"name":38,"class":39},"Paris Translational Research Center for Organ Transplantation","OTHER",2,{"id":42,"slug":43,"hasResults":11,"nctId":44,"briefTitle":45,"officialTitle":46,"acronym":4,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":16,"minAge":48,"maxAge":49,"enrollmentInfo":50,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":52,"conditions":53,"keywords":54,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":56,"lastUpdatePostDateStruct":57,"startDateStruct":58,"completionDateStruct":60,"leadSponsor":62,"locationsCount":63},"100633876","personalized-stories-for-pediatric-kidney-recipients-100633876","NCT07532382","Personalized Stories for Pediatric Kidney Recipients","Generating Personalized Stories With Artificial Intelligence for Pediatric Kidney Recipients","Inclusion Criteria:\n\n* Age 5-12 years inclusive at enrolment.\n* Recipient of a kidney transplant.\n* Clinically stable at enrolment (no active rejection, acute infection, or current hospitalization for a graft-related complication).\n* Fluency in French or English.\n* Written informed consent from parent(s)\u002Flegal guardian(s); child assent when age-appropriate.\n\nExclusion Criteria:\n\n* Severe cognitive impairment precluding engagement with narrative content.\n* Mental state not allowing participation.\n* Family unwilling or unable to commit to the study timeline and interview requirements.","5 Years","12 Years",{"count":51,"type":20},100,"Pediatric kidney transplant recipients often face major psychosocial challenges that are difficult to address with existing tools. This study evaluates whether clinically supervised AI can generate personalized, age-adapted therapeutic stories for these children and their families.",[24],[55],"Artificial intelligence","2026-04-08",{"date":34,"type":32},{"date":59,"type":32},"2026-03-01",{"date":61,"type":20},"2026-12-01",{"name":38,"class":39},1,{"id":65,"slug":66,"hasResults":11,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":4,"eligibilityCriteria":70,"healthyVolunteers":71,"sex":16,"minAge":72,"maxAge":73,"enrollmentInfo":74,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":76,"conditions":77,"keywords":79,"overallStatus":85,"whyStopped":4,"lastUpdateSubmitDate":86,"lastUpdatePostDateStruct":87,"startDateStruct":89,"completionDateStruct":91,"leadSponsor":93,"locationsCount":63},"100599955","molecular-transcriptomics-in-diagnosing-pediatric-kidney-transplant-rejection-the-panda-kids-atlas-study-100599955","NCT07091214","Molecular Transcriptomics in Diagnosing Pediatric Kidney Transplant Rejection: the PANDA-Kids-ATLAS Study","Precision Allograft Rejection Using Novel Diagnostic Approaches in Kidney Transplantation - Allograft Transcriptomics Landscape Analysis Using Sequencing (the PANDA-Kids-ATLAS Study)","Inclusion Criteria:\n\n* Age ≤ 21 years\n* Single kidney transplant recipients (deceased or living donor)\n* Written informed consent from patients\u002Fguardians\n\nExclusion Criteria:\n\n* Multi-organ transplantation history\n* Biopsies with insufficient tissue",true,"0 Years","21 Years",{"count":75,"type":20},600,"Children with kidney failure have markedly increased mortality and face repeated transplantation over their lifetime due to limited allograft half-life (12-15 years). Current biopsy-based diagnoses of rejection (using Banff 2022 criteria) suffer from variability and limited sensitivity. PANDA-Kids-ATLAS will analyze up to 600 pediatric FFPE kidney biopsies across multiple centres using the Banff Human Organ Transplant (B-HOT) NanoString panel to develop and validate molecular classifiers of AMR, TCMR and related phenotypes. A secure REDCap database will integrate molecular, pathological and clinical data, aiming to improve early detection, personalize therapy, and enhance long-term graft survival and patient quality of life.",[78],"Kidney Rejection Transplant",[80,81,82,83,84],"transcriptomics","pediatric kidney transplantation","allograft rejection","precision diagnosis","molecular classifiers","NOT_YET_RECRUITING","2025-07-28",{"date":88,"type":32},"2025-07-29",{"date":90,"type":20},"2025-09-01",{"date":92,"type":20},"2028-12-31",{"name":38,"class":39},{"id":95,"slug":96,"hasResults":11,"nctId":97,"briefTitle":98,"officialTitle":99,"acronym":4,"eligibilityCriteria":100,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":101,"enrollmentInfo":102,"targetDuration":4,"studyType":21,"phases":4,"briefSummary":103,"conditions":104,"keywords":4,"overallStatus":28,"whyStopped":4,"lastUpdateSubmitDate":105,"lastUpdatePostDateStruct":106,"startDateStruct":108,"completionDateStruct":110,"leadSponsor":112,"locationsCount":113},"100542381","molecular-landscape-of-microvascular-inflammation-in-kidney-allografts-100542381","NCT06342128","Molecular Landscape of Microvascular Inflammation in Kidney Allografts","Comprehensive Multiscale Characterization of the Molecular Landscape of Microvascular Inflammation in Kidney Allografts","Inclusion Criteria:\n\n\\- Adult kidney transplant recipients, with at least one kidney transplant biopsy performed and assessed according to the international Banff 2022 classification, with or without lesions of microvascular inflammation\n\nExclusion Criteria:\n\n* Inadequate biopsy according to the Banff classification\n* Missing data for Banff lesion scores, donor-specific antibody status, C4d staining\n* Biopsies showing histological signs of ischemia-reperfusion\n* Combined transplantation and kidney transplantation after a non-kidney solid organ transplantation","100 Years",{"count":75,"type":20},"Microvascular inflammation in kidney allografts has been widely reappraised in the recent update of Banff classification. There is a critical need to better understand the pathophysiological mechanisms associated with the various phenotypes of microvascular inflammation that are observed in kidney transplants, particularly in order to develop targeted therapeutic approaches.",[78],"2025-05-27",{"date":107,"type":32},"2025-05-31",{"date":109,"type":32},"2022-01-01",{"date":111,"type":20},"2025-12",{"name":38,"class":39},3,""]