[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Perspectum\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":146},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,6,0,[8,38,62,86,104,123],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":23,"conditions":24,"keywords":4,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":27,"lastUpdatePostDateStruct":28,"startDateStruct":31,"completionDateStruct":33,"leadSponsor":35,"locationsCount":4},"100644272","global-reference-ranges---mexico-100644272",false,"NCT07664982","Global Reference Ranges - Mexico","Global Reference Ranges (GRR) for Magnetic Resonance Imaging of Intra-abdominal Organs in Healthy Adults From Different Ethnic Groups - Mexico","GRR Mexico","Inclusion Criteria:\n\n* Male or female at least 18 years of age\n* Self-reported healthy\n* Willing and able to give informed consent for participation in the study\n* Willing and able to undergo an MRI\n\nExclusion Criteria:\n\n* History of cardiovascular disease as follows:\n\n  * Myocardial infarction\n  * Heart failure\n  * Cardiomyopathy\n  * Stroke\n  * Hospital admission\u002Fdischarge for unstable angina\n  * Heart surgery\n  * Unstable angina\n  * Transient ischemic attack\n* Presence of CVD risk factors such as hypertension, hyperlipidaemia, Type 2 diabetes, BMI \\> 30 kg\u002Fm2, smoker (current\u002Fex-smoker)\n* History of non-cardiac diseases related to the lungs, liver, kidneys, pancreas or spleen judged by the study investigator as therefore unsuitable to participate in the study\n* The participant may not enter the study if they have any contraindication to magnetic resonance imaging (standard MRI exclusion criteria including pregnancy, extensive tattoos, pacemaker, shrapnel injury, severe claustrophobia)\n* Any other cause, including a significant disease or disorder which, in the opinion of the investigator, may either put the participant at risk because of participation in the study, or may influence the participant's ability to participate in the study","ALL","18 Years",{"count":20,"type":21},50,"ESTIMATED","OBSERVATIONAL","The investigators aim to undertake the Global Reference Range Study (GRR) to establish a set of healthy adult reference values for measures of fibroinflammation, fat and size\u002Fvolumes for the liver, and other abdominal and thoracic organs to assess, compare, and if necessary, propose ethnicity specific reference ranges for these measurements.",[25],"Healthy Adult Participants","NOT_YET_RECRUITING","2026-06-17",{"date":29,"type":30},"2026-06-24","ACTUAL",{"date":32,"type":21},"2026-08",{"date":34,"type":21},"2029-08",{"name":36,"class":37},"Perspectum","INDUSTRY",{"id":39,"slug":40,"hasResults":11,"nctId":41,"briefTitle":42,"officialTitle":43,"acronym":44,"eligibilityCriteria":45,"healthyVolunteers":46,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":47,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":49,"conditions":50,"keywords":4,"overallStatus":52,"whyStopped":4,"lastUpdateSubmitDate":53,"lastUpdatePostDateStruct":54,"startDateStruct":56,"completionDateStruct":58,"leadSponsor":60,"locationsCount":61},"100447731","research-and-development-of-novel-quantitative-magnetic-resonance-imaging-mri-techniques-in-a-single-scan-for-multiple-organ-application-100447731","NCT05110248","Research and Development of Novel Quantitative Magnetic Resonance Imaging (MRI) Techniques in a Single Scan for Multiple Organ Application","Research and Development of Novel Quantitative Magnetic Resonance Imaging (MRI) Techniques in a Single Scan for Multiple Organ Application (RADIUS)","RADIUS","Inclusion Criteria:\n\n* Adults aged 18 years and older\n* Participant is willing and able to give informed consent for participation in the study\n* The participant has a level of English proficiency that allows them to communicate well with the investigator and could comply with study requirements.\n* The participant is willing and able to undergo MRI scan.\n\nExclusion Criteria:\n\n* Any contraindication to magnetic resonance imaging (incl. pregnancy, nonremovable electronic implants including cochlear implants, infusion pumps, and pacemakers, shrapnel injury, severe claustrophobia, allergic reaction to contrast agents)\n* Any other cause, including a significant disease or disorder which, in the opinion of the investigator, may either put the participant at risk because of participation in the study, or may influence the participant's ability to participate in the study\n* The participant may be excluded where body habitus is likely to make MRI or echocardiography\u002Fultrasound uncomfortable or unlikely to yield analysable images, and BMI more than 40-45",true,{"count":48,"type":21},600,"Cross-sectional observational study to improve MRI data acquisition techniques by optimising MRI sequences for multiple organs and assessing the repeatability and reproducibility of multiparametric MRI, in healthy volunteers.",[51],"Multiple","RECRUITING","2026-05-18",{"date":55,"type":30},"2026-05-20",{"date":57,"type":30},"2021-11-15",{"date":59,"type":21},"2031-04-30",{"name":36,"class":37},1,{"id":63,"slug":64,"hasResults":11,"nctId":65,"briefTitle":66,"officialTitle":67,"acronym":4,"eligibilityCriteria":68,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":69,"enrollmentInfo":70,"targetDuration":4,"studyType":72,"phases":73,"briefSummary":75,"conditions":76,"keywords":4,"overallStatus":52,"whyStopped":4,"lastUpdateSubmitDate":53,"lastUpdatePostDateStruct":78,"startDateStruct":80,"completionDateStruct":82,"leadSponsor":84,"locationsCount":85},"100366672","non-invasive-quantification-of-liver-health-in-nash-n-quan-100366672","NCT04054310","Non-Invasive Quantification of Liver Health in NASH (N-QUAN)","Non-Invasive Quantification of Liver Health in NASH (N-QUAN): A Prospective Diagnostic Accuracy Study","Inclusion Criteria:\n\n* Male and Female subjects aged between 18 and 75 years old\n* Ability to understand and sign a written informed consent forms\n* Patients scheduled to undergo a standard of care diagnostic liver biopsy as follows\n* Percutaneous biopsy with a 16 gauged needle passed into the right lobe\n* Trans-jugular biopsy with an 18 gauged needle passed into the right lobe\n* Patients who are suspected of having NAFLD, who are being considered for treatment, and presenting with two or more of the following risk factors for NASH\n* Elevated liver enzymes (ALT≥40)\n* BMI≥25kG\u002Fm\\^2\n* Hypertension\n* Type II diabetes\n* Dyslipidameia\n* Low High-density lipoprotein (HDL) (\\\u003C40mg\u002Fdl in men or \\\u003C50mg\u002Fdl in women)\n* Hypertriglyceridemia (≥150mg\u002Fdl)\n* Hypercholestrolemia (≥200mg\u002Fdl)\n* Triglycerides (TG)\u002FHDL\\>5.0\n\nExclusion Criteria:\n\n* Prior histopathological diagnosis of NASH\n* Inability to undergo a liver biopsy\n* Prior or planned liver transplantation\n* Patient scheduled to undergo a laparoscopic or wedge liver biopsy or biopsy taken from the left lobe\n* Participation in an investigational new drug (IND) trial in the 30 days before enrolment\n* Other known causes of chronic liver disease based on clinical criteria at the study site such as the following:\n* Alcoholic liver disease\n* Primary biliary cirrhosis\n* Primary sclerosing cholangitis\n* Autoimmune Hepatitis\n* Wilson's disease, hemochromatosis, iron overload\n* Alpha\u002F1\u002FAntitrypsin (A1AT) deficiency\n* HCV, HBV\n* History or diagnosis of cirrhosis and or hepatic decompensation including ascites, hepatic encephalopathy or variceal bleeding\n* Clinically relevant drug or alcohol abuse within 12 months of screening\n* Any contradiction or significant limitation to MRI scanning\n* Claustrophobia preventing MR imaging (requires 15-30 minutes in scanning)\n* Pacemaker or another implanted device\n* Metal in body (such as an aneurysm clip) that might produce artefacts on abdominal MRI or might be adversely impacted by a high magnetic field\n* Inability to lie flat, remain still or briefly hold breath as necessary during MR imaging\n* Medical condition likely to produce significant hypervolemia like congestive heart failure\n* Severe obesity complicating positioning in MR scanner\n* Weight reduction surgery within 3 years\n* Concomitant medical illnesses per investigators discretion (such as HIV infection, recent major surgery, uncontrolled heart disease, concurrent infection or fever of unknown origin, illicit drug use, cancer\n* Clinically significant medical or psychiatric condition considered a high risk participation in an investigational study\n* Failure to give informed consent","75 Years",{"count":71,"type":21},225,"INTERVENTIONAL",[74],"NA","To evaluate, in patients with suspected NASH referred for liver biopsy, the diagnostic performance of CT1 at discriminating those with NAS≥4 \\& F≥2 from those without.",[77],"NASH - Nonalcoholic Steatohepatitis",{"date":79,"type":30},"2026-05-19",{"date":81,"type":30},"2020-08-05",{"date":83,"type":21},"2026-06-01",{"name":36,"class":37},7,{"id":87,"slug":88,"hasResults":11,"nctId":89,"briefTitle":90,"officialTitle":90,"acronym":91,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":92,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":93,"conditions":94,"keywords":4,"overallStatus":26,"whyStopped":4,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":97,"startDateStruct":99,"completionDateStruct":101,"leadSponsor":103,"locationsCount":4},"100605742","global-reference-ranges---singapore-100605742","NCT07166471","Global Reference Ranges - Singapore","GRR Singapore",{"count":20,"type":21},"We aim to undertake the Global Reference Range Study (GRR) to establish a set of healthy adult reference values for measures of fibroinflammation, fat and size\u002Fvolumes for the liver, and other abdominal and thoracic organs to assess, compare, and if necessary, propose ethnicity specific reference ranges for these measurements.",[95],"Healthy Participants","2025-11-27",{"date":98,"type":30},"2025-12-05",{"date":100,"type":21},"2025-12-31",{"date":102,"type":21},"2027-09",{"name":36,"class":37},{"id":105,"slug":106,"hasResults":11,"nctId":107,"briefTitle":108,"officialTitle":108,"acronym":109,"eligibilityCriteria":110,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":111,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":113,"conditions":114,"keywords":4,"overallStatus":52,"whyStopped":4,"lastUpdateSubmitDate":96,"lastUpdatePostDateStruct":116,"startDateStruct":117,"completionDateStruct":119,"leadSponsor":121,"locationsCount":122},"100443668","uk-imaging-diabetes-study-seeing-diabetes-clearly-100443668","NCT05057403","UK Imaging Diabetes Study Seeing Diabetes Clearly","UKIDS","Inclusion Criteria:\n\n* Male or female at least 18 years of age and diagnosed with type 2 diabetes, with or without diabetic retinopathy.\n* Participant willing and able to give informed consent for participation in the study.\n\nExclusion Criteria:\n\nIn 12 months prior to consent, evidence of existing cardiovascular event defined as at least one of:\n\n* myocardial infarction\n* ischaemic stroke\n* hospital admission\u002Fdischarge for unstable angina\n* heart surgery\n* unstable angina\n* transient ischemic attack\n* The participant may not enter the study if they have any contraindication to magnetic resonance imaging (standard MR exclusion criteria including pregnancy, extensive tattoos, pacemaker, shrapnel injury, severe claustrophobia).\n* Patients with known autoimmune hepatitis, viral hepatitis, Wilson's disease or known significant structural renal tract abnormality.\n* Patients with known alcohol dependency.\n* Any other cause, including a significant disease or disorder which, in the opinion of the investigator, may either put the participant at risk because of participation in the study, or may influence the participant's ability to participate in the study",{"count":112,"type":21},1000,"Prospective, observational cohort study to cross-sectionally assess the health of multiple organs, using multiparametric abdominal magnetic resonance imaging (MRI) scan, and understand if resulting MRI metrics can predict future clinical events over a period of 5 years, in adult patients with type 2 diabetes lacking history of cardiovascular disease.",[115],"Type2 Diabetes",{"date":98,"type":30},{"date":118,"type":30},"2022-05-30",{"date":120,"type":21},"2034-06",{"name":36,"class":37},12,{"id":124,"slug":125,"hasResults":11,"nctId":126,"briefTitle":127,"officialTitle":128,"acronym":129,"eligibilityCriteria":130,"healthyVolunteers":46,"sex":17,"minAge":18,"maxAge":4,"enrollmentInfo":131,"targetDuration":4,"studyType":22,"phases":4,"briefSummary":132,"conditions":133,"keywords":135,"overallStatus":52,"whyStopped":4,"lastUpdateSubmitDate":139,"lastUpdatePostDateStruct":140,"startDateStruct":142,"completionDateStruct":143,"leadSponsor":145,"locationsCount":61},"100600527","haemdall-developing-a-quantitative-mri-biomarker-of-infratentorial-superficial-siderosis-of-the-central-nervous-system-100600527","NCT07098650","Haemdall: Developing a Quantitative MRI Biomarker of Infratentorial Superficial Siderosis of the Central Nervous System","Haemdall: Developing a Quantitative MRI Biomarker of Classical (Infratentorial) Superficial Siderosis of the Central Nervous System","Haemdall","Inclusion Criteria:\n\nSuperficial siderosis cohort:\n\n* Male or female adults of 18 years of age or older with a confirmed diagnosis of superficial siderosis\n* Participants who have the capacity and a level of English proficiency that allows him\u002Fher to communicate well with the Investigator, understand and comply with the requirements of the investigation, read all participant facing documentation, as well as read and sign the informed consent form.\n* Participants willing and able to give informed consent for participation in the investigation\n\nHealthy cohort:\n\n* Male or female over 18 years of age without a diagnosis of a neurological disorder\n* Participants who have the capacity and a level of English proficiency that allows him\u002Fher to communicate well with the Investigator, understand and comply with the requirements of the investigation, read all participant facing documentation, as well as read and sign the informed consent form.\n* Participants willing and able to give informed consent for participation in the investigation\n\nExclusion Criteria:\n\n* The participant may not enter the investigation if they have any contraindication to magnetic resonance imaging (including pregnancy, extensive tattoos, pacemaker, shrapnel injury or metallic unfixed implanted devices, metallic fragments, severe claustrophobia and cochlear implants)\n* Any other cause, including a significant disease or disorder which, in the opinion of the investigator, may either put the participant at risk because of participation in the investigation, or may influence the result of the investigation, or the participant's ability to participate in the investigation\n* Participants who do not demonstrate the capacity to understand the investigation information or provide informed consent",{"count":20,"type":21},"Haemdall: Using Medical Imaging to measure Brain Iron in Superficial Siderosis.\n\nThis study is looking at a new way of using MRI scans to potentially measure the amount of iron on the surface of the brain. Iron build up in the brain is linked to how superficial siderosis develops. The study will also aim to see if there is a connection between the amount of iron in the brain and common superficial siderosis symptoms. Clinical tests will be used to measure symptoms including tests to measure your hearing, walking \\& balance and participants' ability to remember, think and understand.",[134],"Superficial Siderosis",[136,137,138],"brain iron","MRI","Quantitative Susceptibility Mapping","2025-08-14",{"date":141,"type":30},"2025-08-20",{"date":139,"type":30},{"date":144,"type":21},"2026-12-31",{"name":36,"class":37},""]