[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Pham Ngoc Thach University of Medicine\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":88},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,3,0,[8,42,64],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":30,"lastUpdatePostDateStruct":31,"startDateStruct":34,"completionDateStruct":36,"leadSponsor":38,"locationsCount":41},"100629454","early-phase-1-efficacy-of-05-topical-timolol-eye-drops-in-the-treatment-of-post-inflammatory-erythema-following-acne-vulgaris-100629454",false,"NCT07474883","Efficacy of 0.5% Topical Timolol Eye Drops in the Treatment of Post-Inflammatory Erythema Following Acne Vulgaris","Efficacy of 0.5% Topical Timolol Eye Drops in the Treatment of Post-Inflammatory Erythema Following Acne Vulgaris: A Comparative Study With Intense Pulsed Light (IPL)","Inclusion Criteria: Participants must meet all of the following criteria:\n\n* Age ≥ 12 years with a history of acne vulgaris.\n* Clinically diagnosed with post-inflammatory erythema (PIE) secondary to acne vulgaris.\n* Willing and able to provide informed consent (or assent with parental\u002Fguardian consent if under 18 years of age).\n\nExclusion Criteria:\n\n* Refusal to participate or inability to comply with study procedures (examinations, treatment, follow-up visits), or loss to follow-up.\n* Presence of post-inflammatory hyperpigmentation (PIH) at the study site that may interfere with accurate assessment of erythema.\n* Presence of other dermatologic conditions affecting the treatment area (e.g., atopic dermatitis, rosacea, lupus erythematosus).\n* Known hypersensitivity or adverse reaction to timolol or other beta-adrenergic receptor blockers.\n* Pregnant or breastfeeding women.\n* History of cardiovascular or respiratory conditions contraindicating beta-blocker use (e.g., asthma, atrioventricular block, bradycardia \\\u003C50 beats per minute, hypotension).\n* Use of other topical medications or cosmetic products (except sunscreen) on the study area during the study period.","ALL","12 Years",{"count":19,"type":20},60,"ESTIMATED","INTERVENTIONAL",[23],"EARLY_PHASE1","Post-inflammatory erythema (PIE) is a common sequela of acne vulgaris, characterized by persistent erythematous macules resulting from superficial vascular dilation. Current treatment options include energy-based devices such as intense pulsed light (IPL); however, these modalities may be costly and require specialized equipment.\n\nTimolol, a non-selective beta-adrenergic receptor blocker, has demonstrated vasoconstrictive properties and has been used off-label in dermatology for vascular-related conditions. This study aims to evaluate the efficacy and safety of topical 0.5% timolol ophthalmic solution in improving post-inflammatory erythema secondary to acne vulgaris and to compare its clinical outcomes with those achieved by intense pulsed light (IPL) therapy.\n\nThis prospective comparative study will assess changes in erythema severity using standardized clinical evaluation and objective measurement tools over a defined treatment period. The findings may provide evidence for a cost-effective and accessible therapeutic alternative for managing post-acne erythema.",[26,27,28],"Post Inflammtory Erythema","Acne Vulgaris","Erythema","RECRUITING","2026-03-26",{"date":32,"type":33},"2026-04-01","ACTUAL",{"date":35,"type":20},"2026-03-09",{"date":37,"type":20},"2026-10-09",{"name":39,"class":40},"Pham Ngoc Thach University of Medicine","OTHER",1,{"id":43,"slug":44,"hasResults":11,"nctId":45,"briefTitle":46,"officialTitle":46,"acronym":4,"eligibilityCriteria":47,"healthyVolunteers":11,"sex":16,"minAge":48,"maxAge":4,"enrollmentInfo":49,"targetDuration":4,"studyType":21,"phases":51,"briefSummary":53,"conditions":54,"keywords":4,"overallStatus":56,"whyStopped":4,"lastUpdateSubmitDate":57,"lastUpdatePostDateStruct":58,"startDateStruct":60,"completionDateStruct":61,"leadSponsor":63,"locationsCount":4},"100628753","evaluation-of-the-support-program-to-enhance-self-management-capacity-among-stroke-survivors-100628753","NCT07465744","Evaluation of the Support Program to Enhance Self-management Capacity Among Stroke Survivors","Inclusion Criteria:\n\n* Aged 18 years or older;\n* Clinically diagnosed with ischemic stroke or intracerebral hemorrhage (first-ever or recurrent episode);\n* Assessed by the treating physician as being clinically stable following the acute phase;\n* Mini-Mental State Examination (MMSE) score \\> 18;\n* Scheduled for follow-up after discharge at the Neurology Outpatient Clinic or the Neurology Clinic, Department of Outpatient Services, University Medical Center Ho Chi Minh City;\n* Able to speak and read Vietnamese;\n* Willing to participate in educational sessions within the health self-management program;\n* Able to use a telephone;\n* Having a family member or caregiver accompanying the patient who is able to recognize changes in the patient's physical and mental condition;\n* Providing informed consent to participate in the study.\n\nExclusion Criteria:\n\n* Diagnosed with stroke secondary to cerebrovascular pathology related to malignancy;\n* Diagnosed with psychiatric disorders such as depression, schizophrenia, bipolar disorder, or personality disorders.","18 Years",{"count":50,"type":20},140,[52],"NA","The goal of this interventional study is to develop and evaluate a post-stroke patient support program aimed at enhancing patients' ability to self-management after discharge to home. The main question it aim to answer are:\n\nAfter participating in the support program, do patients show improvements in stroke-related knowledge, independence in activities of daily living, and self-efficacy in managing their health?\n\nResearchers will compare intervention to control group. The control group receive usual care. The intervention group receive usual care and support self management program to see enhance self-efficacy and recovery.\n\nParticipants will:\n\n* Answer a self-report questionnaire\n* Attend to support self management program during 5 sessions in 5 weeks",[55],"Stroke","NOT_YET_RECRUITING","2026-03-10",{"date":59,"type":33},"2026-03-12",{"date":32,"type":20},{"date":62,"type":20},"2026-10-01",{"name":39,"class":40},{"id":65,"slug":66,"hasResults":11,"nctId":67,"briefTitle":68,"officialTitle":69,"acronym":4,"eligibilityCriteria":70,"healthyVolunteers":11,"sex":16,"minAge":71,"maxAge":72,"enrollmentInfo":73,"targetDuration":4,"studyType":75,"phases":4,"briefSummary":76,"conditions":77,"keywords":4,"overallStatus":29,"whyStopped":4,"lastUpdateSubmitDate":80,"lastUpdatePostDateStruct":81,"startDateStruct":83,"completionDateStruct":85,"leadSponsor":87,"locationsCount":41},"100550211","the-incidence-and-risk-factors-of-recurrent-febrile-seizures-and-epilepsy-following-febrile-seizures-100550211","NCT06444126","The Incidence And Risk Factors Of Recurrent Febrile Seizures And Epilepsy Following Febrile Seizures","A Prospective Cohort Study Of The Incidence And Risk Factors Of Recurrent Febrile Seizures And Epilepsy Following Febrile Seizures","Inclusion Criteria:\n\n* Children had a diagnosis of first febrile seizure based on the definition of the International League Against Epilepsy (ILAE) in 1993. That was a seizure occurring in childhood after one month of age associated with a febrile illness not caused by an infection of the central nervous system, without previous neonatal seizures or a previous unprovoked seizure, and not meeting the criteria for other acute symptomatic seizures. Fever is clinically a temperature of at least 38°C by any method as recorded either in the emergency department, outpatient clinics, or as noted in the medical history, as well as measured upon admission to the inpatient departments.\n* Patients were between 1 month and 8 years of age\n* Agreement from parents with written informed consent\n\nExclusion Criteria:\n\n* Febrile paroxysmal events were atypical for seizures\n* Underlying neurological conditions that increase the likelihood of epilepsy\n* Unwillingness to return for follow-up","1 Month","8 Years",{"count":74,"type":20},650,"OBSERVATIONAL","The goal of this observational study is to learn about the recurrence and development of epilepsy in children hospitalized with their first febrile seizures. The main questions it aims to answer are:\n\n* What is the risk of recurrence after the first febrile seizure and what are the risk factors for recurrent febrile seizures in Vietnamese children?\n* What is the risk of developing epilepsy later in life and what are the risk factors for developing epilepsy in Vietnamese children who have had febrile seizures?",[78,79],"Febrile Seizures","Epilepsy in Children","2024-06-06",{"date":82,"type":33},"2024-06-10",{"date":84,"type":33},"2023-03-15",{"date":86,"type":20},"2025-09-15",{"name":39,"class":40},""]