[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Philipp Schuetz\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":72},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,2,0,[8,43],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":4,"enrollmentInfo":18,"targetDuration":4,"studyType":21,"phases":22,"briefSummary":24,"conditions":25,"keywords":27,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":31,"lastUpdatePostDateStruct":32,"startDateStruct":35,"completionDateStruct":37,"leadSponsor":39,"locationsCount":42},"100579577","pancrelipase-with-nutritional-supplement-in-patients-at-risk-of-malnutrition-effort-enzo-100579577",false,"NCT06826105","Pancrelipase With Nutritional Supplement in Patients at Risk of Malnutrition (EFFORT-ENZO)","Effect of Low Dose Pancrelipase With an Oral Nutritional Supplement to Improve Nutrient Bioavailability in Patients at Increased Risk of Malnutrition","Inclusion Criteria:\n\n* Informed Consent as documented by signature\n* Male or female 70 years of age or older\n* Hospitalized at site\n* Nutrition Risk Screening 2002 (NRS-2002) ≥ 3\n* eGFR ≥ 30 mL\u002Fmin\u002F1.73 m2 (EPI-CKD) based on medical history (no older than 6 months)\n* Ability to eat orally\n\nExclusion Criteria:\n\n* Patients with acute cardiovascular event ≤ 2 days\n* Patients with terminal conditions\n* Patients diagnosed with pancreatic exocrine insufficiency (EPI) treated with pancreatic enzyme replacement therapy (PERT)\n* Patients having a planned transplant or new-onset dialysis in the next 6 months.\n* Patients having a colectomy, resection of the small intestine or cholecystectomy\n* Known hypersensitivity to any of the substances or excipients of the ONS or the medicinal product","ALL","70 Years",{"count":19,"type":20},20,"ESTIMATED","INTERVENTIONAL",[23],"NA","This study investigates if pancreatic enzymes in combination with oral nutritional supplement can improve nutrient bioavailability in older people with malnutrition or at risk of malnutrition.",[26],"Malnutrition",[28,29],"Pancrelipase","Oral nutritional supplements","RECRUITING","2025-09-24",{"date":33,"type":34},"2025-09-30","ACTUAL",{"date":36,"type":34},"2025-09-22",{"date":38,"type":20},"2026-01",{"name":40,"class":41},"Philipp Schuetz","OTHER",1,{"id":44,"slug":45,"hasResults":11,"nctId":46,"briefTitle":47,"officialTitle":48,"acronym":49,"eligibilityCriteria":50,"healthyVolunteers":11,"sex":16,"minAge":51,"maxAge":4,"enrollmentInfo":52,"targetDuration":4,"studyType":21,"phases":54,"briefSummary":55,"conditions":56,"keywords":57,"overallStatus":30,"whyStopped":4,"lastUpdateSubmitDate":63,"lastUpdatePostDateStruct":64,"startDateStruct":66,"completionDateStruct":68,"leadSponsor":70,"locationsCount":71},"100433628","effect-of-continued-nutritional-support-at-hospital-discharge-on-mortality-frailty-functional-outcomes-and-recovery-100433628","NCT04926597","Effect of Continued Nutritional Support at Hospital Discharge on Mortality, Frailty, Functional Outcomes and Recovery","Effect of Continued Nutritional Support at Hospital Discharge on Mortality, Frailty, Functional Outcomes and Recovery Trial: The EFFORT II Project","EFFORT II","Inclusion Criteria:\n\n* Informed Consent as documented by signature\n* Adult (age ≥18 years), medical patients\n* Nutritional risk screening using the Nutritional Risk Screening (NRS): total score ≥3 points consisting of ≥1 points for impairment of the nutritional status \\[weight loss \\>5% in 3 month or food intake of 50-75% in the last week before hospital admission\\] plus ≥1 for the severity of the disease (i.e., cancer, chronic kidney disease, chronic heart failure, COPD) and other chronic diseases according to the definition of the \"National Center for Chronic Disease Prevention and Health Promotion\": Chronic diseases are defined broadly as conditions that last 1 year or more and require ongoing medical attention or limit activities of daily living or both .\n\nExclusion Criteria:\n\n* after surgery\n* unable to ingest oral nutrition\n* need for long-term nutrition,\n* terminal condition\n* acute pancreatitis or acute liver failure\n* patients discharged to a nursing home\n* patients unlikely to comply with nutritional support treatment (e.g., dementia)\n* COVID-Hospitalisation requiring intensive care","18 Years",{"count":53,"type":20},1200,[23],"This study is to compare the sustained post-discharge nutritional support to reach individual energy and protein goals to usual care home nutrition in medical patients at nutritional risk.",[26],[58,59,60,61,62],"Nutritional Support","Oral Nutritional Supplements","Frailty","Mortality","Morbidity","2024-11-18",{"date":65,"type":34},"2024-11-20",{"date":67,"type":34},"2021-08-05",{"date":69,"type":20},"2026-12",{"name":40,"class":41},18,""]