[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Polish Academy of Sciences\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":50},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,1,0,[8],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":15,"eligibilityCriteria":16,"healthyVolunteers":11,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100562496","the-personalized-psychological-treatment-for-psychosis-100562496",false,"NCT06603922","The Personalized Psychological Treatment for Psychosis","Towards a Personalized Medicine Approach to Psychological Treatment for Psychosis","PERMEPSY","Inclusion Criteria:\n\n1. Inpatients and outpatients with a DSM-IV-R and DSM-5 diagnosis of non-affective psychosis or Clinical High Risk for psychosis.\n2. Presence of positive symptoms during the last year (PANSS delusions, suspiciousness or grandiosity \\>=3).\n3. Adults, 18 - 65 years of age\n4. Stable condition with no expected changes in medication (information from clinical services).\n5. Lack of severe cognitive deficits (global assessment or\u002Fand information from clinical services);\n\nExclusion Criteria:\n\n1. Having received MCT in the previous year.\n2. Neurological disorder, a history of head trauma or premorbid IQ below 70 (based on medical reports and\u002For other sources);\n3. A score above 5 in the \"Hostility\" and the \"Suspiciousness\" items of the PANSS Positive subscale (to preserve group dynamics).\n4. aggressive behavior (reports from clinical services if available)\n5. High risk of suicide (verified with DIAMOND)","ALL","18 Years","65 Years",{"count":21,"type":22},252,"ESTIMATED","INTERVENTIONAL",[25],"NA","The main aim of the clinical trial is to validate the Machin Learning (ML) predictive model for personalized Metacognitive Training (MCT) by comparing classic MCT to personalized MCT (P-MCT) among patients diagnosed with psychosis who had a history of delusions. More precisely, we will compare classic MCT to P-MCT in a randomized clinical trial.We expect personalised MCT treatment will see more improvement than classical MCT in outcome variables measuring treatment efficacy.",[28,29,30],"Schizophrenia","Psychosis","Schizophrenia Spectrum and Other Psychotic Disorders",[32,33,34,35,36],"personalized medicine","psychological treatment","metacognitive training","machine learning","software platform","NOT_YET_RECRUITING","2024-09-16",{"date":40,"type":41},"2024-09-19","ACTUAL",{"date":43,"type":22},"2024-10-01",{"date":45,"type":22},"2026-05-31",{"name":47,"class":48},"Polish Academy of Sciences","OTHER",6,""]