[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Postgraduate Institute of Dental Sciences Rohtak\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":600},{"pageToken":4,"total":5,"offset":6,"count":7,"results":8},null,44,0,25,[9,48,79,104,129,153,179,206,226,248,269,292,311,330,353,371,394,420,439,464,491,512,532,552,577],{"id":10,"slug":11,"hasResults":12,"nctId":13,"briefTitle":14,"officialTitle":15,"acronym":4,"eligibilityCriteria":16,"healthyVolunteers":12,"sex":17,"minAge":18,"maxAge":19,"enrollmentInfo":20,"targetDuration":4,"studyType":23,"phases":24,"briefSummary":26,"conditions":27,"keywords":31,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":36,"lastUpdatePostDateStruct":37,"startDateStruct":40,"completionDateStruct":42,"leadSponsor":44,"locationsCount":47},"100641352","effectiveness-of-subgingival-instrumentation-on-delaying-end-stage-renal-disease-among-chronic-kidney-disease-patients-100641352",false,"NCT07635797","Effectiveness of Subgingival Instrumentation on Delaying End-stage Renal Disease Among Chronic Kidney Disease Patients","Effectiveness of Subgingival Instrumentation on Delaying End-stage Renal Disease Among Chronic Kidney Disease Patients: A Non-Randomized Clinical Study","Inclusion Criteria:\n\n* Patients aged 40-70 years.\n* Type 2 diabetes mellitus with chronic kidney disease and currently on oral hypoglycaemic agents.\n* Diagnosed with Stage IV or V (eGFR between 15-20 mL\u002Fmin\u002F1.73m²).\n* Not undergoing dialysis.\n* Presence of ≥20 natural teeth.\n* Diagnosed with moderate (Stage II) (as per 2017 World Workshop classification) (Interdental CAL at site of greatest loss \\>2mm but \\\u003C5 mm in ≥ 2 non-adjacent teeth).\n* Willingness to provide written informed consent.\n\nExclusion Criteria:\n\n* Patients already undergoing haemodialysis or renal transplantation.\n* Patients on insulin therapy or taking SGLT2 inhibitors and GLP-1 receptor agonists.\n* HbA1c level \\>8 %.\n* Any Periodontal therapy within past 6 months.\n* Immunocompromised patients.\n* Any history of tobacco use.\n* Pregnant or lactating women.","ALL","40 Years","70 Years",{"count":21,"type":22},40,"ESTIMATED","INTERVENTIONAL",[25],"NA","Chronic kidney disease (CKD) and periodontitis share a bidirectional inflammatory relationship, with cytokines such as IL-6, TNF-α, and hsCRP driving progression in both conditions. Non-surgical periodontal therapy (NSPT) has shown reductions in systemic inflammatory markers with emerging evidence of improved renal function, yet robust randomized controlled trials targeting pre-dialysis stage IV-V diabetic CKD patients remain lacking. In the Indian context, where diabetes-related CKD is rapidly rising and access to dialysis is limited, there is a clear lacuna in literature regarding the effectiveness of NSPT in delaying progression to end-stage renal disease. Hence, the present non-randomized clinical study is undertaken to address this gap.",[28,29,30],"Chronic Kidney Disease","Periodontitis","End Stage Renal Disease (ESRD)",[28,32,29,33,34],"Subgingival Instrumentation","End Stage Renal Disease","Dialysis","NOT_YET_RECRUITING","2026-06-16",{"date":38,"type":39},"2026-06-18","ACTUAL",{"date":41,"type":22},"2026-07",{"date":43,"type":22},"2027-12",{"name":45,"class":46},"Postgraduate Institute of Dental Sciences Rohtak","OTHER",1,{"id":49,"slug":50,"hasResults":12,"nctId":51,"briefTitle":52,"officialTitle":53,"acronym":54,"eligibilityCriteria":55,"healthyVolunteers":12,"sex":17,"minAge":56,"maxAge":57,"enrollmentInfo":58,"targetDuration":4,"studyType":23,"phases":60,"briefSummary":61,"conditions":62,"keywords":64,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":71,"lastUpdatePostDateStruct":72,"startDateStruct":74,"completionDateStruct":76,"leadSponsor":78,"locationsCount":47},"100592085","effect-of-microneedling-with-coronally-advanced-flap-for-management-of-rt1-gingival-recession-in-thin-gingival-phenotype-100592085","NCT06988839","Effect Of Microneedling With Coronally Advanced Flap For Management of RT1 Gingival Recession In Thin Gingival Phenotype","Patient-Centered And Clinical Outcomes Of Microneedling With Coronally Advanced Flap For Management of RT1 Gingival Recession In Thin Gingival Phenotype : A Randomized Controlled Clinical Trial","RT1","Inclusion Criteria:\n\n* Presence of isolated RT1 buccal maxillary gingival recessions in esthetic zone with thin gingival phenotype (Gingival thickness≤1mm) associated with esthetic complaints and\u002For dental sensitivity and otherwise systemically healthy.\n* Gingival Recession ≥2mm , Keratinized tissue width≥2mm and clinically identifiable cementoenamel junction\n* Age 20years-50 years\n* Patient demonstrating compliance for maintaining good oral hygiene after Phase 1 therapy Plaque index (PI) \\\u003C1, Gingival Index (GI) \\\u003C1\n* Providing a written and verbal informed consent.\n\nExclusion Criteria:\n\n* Patient with systemic disease that can influence the outcome of therapy.\n* Pregnant females or on oral contraceptive pills or hormone replacement therapy.\n* Smokers and patients undergoing orthodontic therapy\n* Physically and mentally impaired patients.\n* Non vital, malpositioned tooth\n* Presence of cervical abrasions or restorations in the area\n* Previous history of periodontal surgery on the involved sites.","20 Years","50 Years",{"count":59,"type":22},36,[25],"The goal of this clinical trial is to explore the effect of microneedling to increase the gingival tissue thickness which could improve the outcome of root coverage in coronally advanced flap procedure in thin gingival phenotype. The main question it aims to answer is that :\n\nDoes the use of microneedling procedure followed by coronally advanced flap has similar outcomes of root coverage in recession type 1 (RT1) gingival recession i.e. buccal gingival recessions without interdental clinical attachment loss in thin gingival phenotype as compared to coronally advanced flaps with connective tissue graft.\n\nSystemically healthy patients having isolated upper RT1 gingival recession will be assigned into two groups. Microneedling will be performed in one group (4 sessions each at a 10 days interval) followed by coronally advanced flap operation (at an interval of 2 months) and coronally advanced flap with connective tissue graft will be performed in the other group. Follow-up will be done at 1 month, 3 months and 6 months for evaluation of primary and secondary outcomes.",[63],"Gingival Recession",[65,66,67,68,69],"gingival recession","percutaneous collagen induction","root coverage","connective tissue graft","microneedle","RECRUITING","2026-06-11",{"date":73,"type":39},"2026-06-12",{"date":75,"type":39},"2025-06-26",{"date":77,"type":22},"2026-12",{"name":45,"class":46},{"id":80,"slug":81,"hasResults":12,"nctId":82,"briefTitle":83,"officialTitle":84,"acronym":4,"eligibilityCriteria":85,"healthyVolunteers":12,"sex":17,"minAge":86,"maxAge":87,"enrollmentInfo":88,"targetDuration":4,"studyType":23,"phases":90,"briefSummary":91,"conditions":92,"keywords":94,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":98,"lastUpdatePostDateStruct":99,"startDateStruct":100,"completionDateStruct":102,"leadSponsor":103,"locationsCount":47},"100642867","effect-of-mobile-health-on-plaque-control-efficacy-in-molars-with-furcation-involvement-100642867","NCT07642895","Effect of Mobile Health on Plaque Control Efficacy in Molars With Furcation Involvement","Effect of Mobile Health on Plaque Control Efficacy in Molars With Furcation Involvement: A Randomized Controlled Clinical Trial","Inclusion Criteria:\n\n* Systemically healthy individuals with clinically visible furcation entrance in mandibular molars in Stage III periodontitis\n* Horizontal bone loss extent ≥ 3mm29 and vertical bone loss ( Subclass A\u002FB)30\n* Access to mobile phone\n\nExclusion Criteria:\n\n* Presence of systemic diseases that could influence the outcome of periodontal therapy (Diabetes mellitus, Hypertension)\n* Smoking\u002Falcohol consumption\n* Teeth with Grade II\u002FIII mobility\n* History of periodontal treatment or antibiotic therapy in the last 6 months\n* Non-vital and carious teeth to be restored\n* Physically and mentally impaired patients\n* Furcation involvement with cervical enamel projections, enamel pearls and bifurcation ridges","18 Years","55 Years",{"count":89,"type":22},76,[25],"Furcation involvement (FI) refers to a condition in which the progression of the periodontal disease process invades the bifurcation and trifurcation of multirooted teeth. Furcation involvement, present a clinical challenge due to its anatomic complexity and reduced access for adequate plaque control which may leads to further periodontal breakdown. Consequently, maintenance of adequate oral hygiene is critical in these sites.\n\nIt has been shown that poor oral hygiene, together with the persistence of periodontal risk factors, leads to further disease progression, treatment failure, and disease recurrence.\n\nMobile health can serve as a valuable adjunctive approach by aiding in behavioral reinforcement through real-time reminders. With widespread mobile phone usage in India, mHealth interventions are feasible. The role of mHealth in management of furcation involved sites has still not been explored. Therefore, this randomized controlled clinical trial aims to evaluate the effectiveness of mobile health reinforcements in improving plaque control efficacy at in furcation involved sites following non-surgical periodontal therapy, with the potential to enhance patient compliance and prevent further disease progression and disease recurrence.",[93],"Furcation Defects",[95,96,97],"FURCATION","FURCATION INVOLVEMENT","MHEALTH","2026-06-09",{"date":71,"type":39},{"date":101,"type":22},"2026-06",{"date":43,"type":22},{"name":45,"class":46},{"id":105,"slug":106,"hasResults":12,"nctId":107,"briefTitle":108,"officialTitle":109,"acronym":4,"eligibilityCriteria":110,"healthyVolunteers":12,"sex":17,"minAge":111,"maxAge":18,"enrollmentInfo":112,"targetDuration":4,"studyType":23,"phases":114,"briefSummary":115,"conditions":116,"keywords":119,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":121,"lastUpdatePostDateStruct":122,"startDateStruct":124,"completionDateStruct":126,"leadSponsor":128,"locationsCount":47},"100642792","influence-of-proximal-caries-on-outcome-of-direct-pulp-capping-in-permanent-mandibular-molars-with-reversible-pulpitis-100642792","NCT07578662","Influence of Proximal Caries on Outcome of Direct Pulp Capping in Permanent Mandibular Molars With Reversible Pulpitis","Influence of Proximal Caries on Outcome of Direct Pulp Capping in Permanent Mandibular Molars With Reversible Pulpitis: A Prospective Study","Inclusion Criteria:\n\n1. Mature permanent mandibular molars with extremely deep caries that penetrate the entire thickness of dentine as detected on radiograph with reversible pulpitis will be included.\n2. Participant with Reversible pulpitis will be diagnosed clinically based on discomfort experienced by the participant when a stimulus such as cold or sweet is applied and goes away within a couple of seconds following the removal of the stimulus, with no significant radiographic changes in the periapical region of the suspect tooth and the pain experienced is not spontaneous.\n3. The pulpal sensibility will be confirmed through positive response to electric and cold tests (Endo frost) and the presence of bleeding after caries excavation. 4.Pulpal and the periapical diagnosis will be established based on the diagnostic terminology approved by American Association of Endodontists (AAE, 2019).\n\n5.Teeth with a negative response to palpation and percussion testing and radiographic finding of periapical index (PAI) score ≤2 and healthy periodontium (probing pocket depth ≤3 mm and mobility within normal limit) will be included. 6.Teeth in which hemostasis achieved within 5 mins will be included.\n\n7.Only pulp exposures with size 0.5-1 mm will be included\n\n\\-\n\nExclusion Criteria:\n\n1. Mechanical or pulp exposure due to trauma\n2. absence of exposure after excavation of caries\n3. failure to achieve hemostasis within 5 mins\n4. irreversible pulpitis and teeth having periapical lesions\n5. periodontal disease, resorptive defects, calcified canals, as assessed by radiographic examination will serve as criteria for exclusion.\n6. Also immunocompromised, Pregnant and subjects having systemic diseases will be excluded -","15 Years",{"count":113,"type":22},154,[25],"The aim of the study is to assess the Influence of proximal caries on outcome of direct pulp capping in permanent mandibular molars with sign of reversible pulpitis. objective- Primary objective- To evaluate and compare the clinical and radiographic outcome of Direct pulp capping in mandibular molars with occlusal and proximal carious lesions. Secondary objective- To evaluate and compare 1.OHRQoL after Direct pulp capping in occlusal and proximal lesion. 2. Postoperative pain, after Direct pulp capping in occlusal and proximal lesion Subjects of age group 15 - 40 yrs will be included and divided into two groups 1) Permanent mature molars with proximal carious lesion 2)Permanent mature molars with occlusal carious lesion.",[117,118],"Reversible Pulpitis","Extremely Deep Caries",[120],"direct pulp capping","2026-06-08",{"date":123,"type":39},"2026-06-10",{"date":125,"type":39},"2026-04-29",{"date":127,"type":22},"2028-04-28",{"name":45,"class":46},{"id":130,"slug":131,"hasResults":12,"nctId":132,"briefTitle":133,"officialTitle":134,"acronym":4,"eligibilityCriteria":135,"healthyVolunteers":12,"sex":17,"minAge":136,"maxAge":137,"enrollmentInfo":138,"targetDuration":4,"studyType":140,"phases":4,"briefSummary":141,"conditions":142,"keywords":144,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":147,"lastUpdatePostDateStruct":148,"startDateStruct":149,"completionDateStruct":150,"leadSponsor":152,"locationsCount":47},"100643006","mental-health-and-periodontitis-in-probable-bruxers-100643006","NCT07634250","Mental Health and Periodontitis in Probable Bruxers","Association Between Mental Health Status and Periodontitis Among Probable Bruxers","Inclusion Criteria:\n\n1. Adult periodontitis patients with age group 30-50 years diagnosed with probable bruxism.\n2. Presence of minimum 20 teeth excluding third molars.\n\nExclusion Criteria:\n\n* History of systemic disease such as diabetes or autoimmune disease\n* History of drugs having the potential impact on periodontal status like phenytoin, cyclosporin, calcium-channel blockers or antidepressant drugs.\n* Pregnant or lactating females.\n* Post-menopausal women.\n* Patients diagnosed with temporomandibular disorders- pain and tenderness in the masticatory muscles","30 Months","50 Months",{"count":139,"type":22},110,"OBSERVATIONAL","The goal of this observational study is to learn how mental health affects periodontal health in people having teeth grinding (bruxism).\n\nThe main questions it aims to answer are:\n\nDoes poor mental health increase the risk of periodontitis in people with teeth grinding? Does stress link teeth grinding and periodontitis?\n\nParticipants are people who likely have teeth grinding(bruxism) and periodontitis\n\nParticipants will:\n\nAnswer questions about their mental health, including stress Get a periodontal health status check\n\nTeeth grinding(Bruxism) can occur due to stress, smoking, alcohol use, and bite problems. Stress may affect muscle activity and lead to teeth grinding. It can also weaken the body's defense and lead to poor oral care. This may worsen periodontal health.",[143],"Periodontal Disease",[145,146],"mental health status","probable bruxism","2026-06-03",{"date":121,"type":39},{"date":101,"type":22},{"date":151,"type":22},"2026-09",{"name":45,"class":46},{"id":154,"slug":155,"hasResults":12,"nctId":156,"briefTitle":157,"officialTitle":158,"acronym":4,"eligibilityCriteria":159,"healthyVolunteers":12,"sex":17,"minAge":160,"maxAge":57,"enrollmentInfo":161,"targetDuration":4,"studyType":23,"phases":163,"briefSummary":164,"conditions":165,"keywords":168,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":172,"lastUpdatePostDateStruct":173,"startDateStruct":174,"completionDateStruct":176,"leadSponsor":178,"locationsCount":47},"100638375","motivational-interviewing-and-subgingival-instrumentation-outcomes-in-periodontitis-100638375","NCT07618533","Motivational Interviewing and Subgingival Instrumentation Outcomes in Periodontitis","Effect of Motivational Interviewing on the Outcomes of Subgingival Instrumentation in Patients With Periodontitis","Inclusion Criteria:\n\n• Systemically healthy Patients with age group 30-50 years diagnosed with (Stage I-III) periodontitis.\n\nExclusion Criteria:\n\n* Systemic diseases that may affect periodontal disease progression or outcome of treatment\n* Patients on long term antibiotics\n* Pregnant and lactating women\n* Female patients with history of menopause\n* Current orthodontic treatment or planning to undergo orthodontic treatment during study","30 Years",{"count":162,"type":22},66,[25],"Motivational Interviewing (MI) represents a patient centered counselling approach designed to facilitate behaviour change by guiding patients through the exploration and resolution of ambivalence toward positive health actions. Adapting OARS microskills (open ended questions fostering dialogue, affirmations building self-efficacy, reflective listening mirroring emotions, summarization making commitments) intertwined with the RULE framework (resisting the righting reflex, understanding personal motivations, empathic listening, empowering autonomy) helps cultivate patient's intrinsic motivation for sustained oral hygiene adherence. It effectively resolves ambivalence toward plaque control behaviours essential for periodontitis management. Grounded in MI's core spirit of equal partnership, evocation of inner values, acceptance and compassionate support, this approach fosters long term adherence to treatment. This is in contrast to oral hygiene instructions that typically employ a directive advice giving method, where clinicians provide patients with prescriptive guidance on maintaining optimal oral hygiene practices. Periodontitis staging, as defined by the 2017 World Workshop classification, delineates disease severity (Stages I-III), complexity of management, and extent of involvement, while grading (A-C) offers a prognostic indicator of the risk for future progression based on factors such as rate of advancement and responsiveness to therapy. Integrating motivational interviewing (MI) with periodontitis staging and grading creates a structured framework from diagnosis to patient centered action, enhancing adherence to stage specific treatment plans. This study seeks to investigate the influence of MI on Clinical outcomes, Patient motivation, Patient related outcomes and Patient's Self-efficacy in oral hygiene following subgingival instrumentation among patients stratified by periodontitis stage. By doing so, it aims to explore the potential of behavior change interventions to yield not only clinical improvements but also broader health benefits in the management of periodontitis.",[166,29,167],"Motivational Interviewing","Oral Hygiene",[169,170,171],"Motivational interviewing","Periodontitis staging and grading","Treatment adherence","2026-06-01",{"date":147,"type":39},{"date":175,"type":22},"2026-06-26",{"date":177,"type":22},"2027-12-27",{"name":45,"class":46},{"id":180,"slug":181,"hasResults":12,"nctId":182,"briefTitle":183,"officialTitle":184,"acronym":4,"eligibilityCriteria":185,"healthyVolunteers":12,"sex":17,"minAge":160,"maxAge":186,"enrollmentInfo":187,"targetDuration":4,"studyType":140,"phases":4,"briefSummary":189,"conditions":190,"keywords":195,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":172,"lastUpdatePostDateStruct":201,"startDateStruct":202,"completionDateStruct":204,"leadSponsor":205,"locationsCount":4},"100639187","impact-of-distress-level-sleep-quality-and-occlusal-trauma-on-periodontal-status-among-bruxers-100639187","NCT07615153","Impact of Distress Level, Sleep Quality and Occlusal Trauma on Periodontal Status Among Bruxers","Impact of Distress Level, Sleep Quality and Occlusal Trauma on Periodontal Status Among Bruxers - a Cross Sectional Study","Inclusion Criteria:\n\nTest Group:\n\n* Adults aged 30-45 years\n* Patients diagnosed with periodontitis according to the 2017 World Workshop classification of periodontal and peri-implant diseases and conditions.\n* Patients who are probable bruxers according to BRUXSCREEN-Q\n* Minimum of 20 natural teeth\n\nControl Group:\n\n* Adults aged 30-45 years\n* Patients diagnosed with periodontitis according to the 2017 World Workshop classification of periodontal and peri-implant diseases and conditions.\n* Patients who are not probable bruxers according to BRUXSCREEN-Q\n* Minimum of 20 natural teeth\n\nExclusion Criteria:\n\n* Systemic conditions affecting periodontium (e.g., diabetes, auto immune disorders)\n* History of drugs having the potential impact on periodontal status like phenytoin, cyclosporin, calcium-channel blockers or antidepressant drugs\n* Patients with pulpal pathology\n* Pregnant or lactating females","45 Years",{"count":188,"type":22},128,"Increased distress levels and impaired sleep quality are known to exacerbate bruxism by enhancing masticatory muscle activity, leading to excessive and prolonged occlusal forces. These abnormal forces may result in occlusal trauma, which can compromise the adaptive capacity of the periodontal tissues by increasing tooth mobility, widening the periodontal ligament space, and accelerating alveolar bone loss, particularly in the presence of existing periodontal inflammation. Although occlusal trauma alone may not initiate periodontal disease, it can act as an important modifying factor in disease progression. Despite the recognized individual associations of distress, sleep quality, bruxism, and periodontal health, limited evidence exists regarding their combined impact on periodontal status among bruxers. Therefore, evaluating the influence of distress level, sleep quality, and occlusal trauma on periodontal status is essential to better understand disease progression and to facilitate comprehensive, multidisciplinary management strategies for individuals with bruxism.",[29,191,192,193,194],"Bruxism","Sleep Quality","Distress Level","Occlusal Trauma",[196,197,198,199,200],"periodontits","bruxism","sleep quality","distress level","occlusal trauma",{"date":147,"type":39},{"date":203,"type":22},"2026-06-22",{"date":177,"type":22},{"name":45,"class":46},{"id":207,"slug":208,"hasResults":12,"nctId":209,"briefTitle":210,"officialTitle":210,"acronym":4,"eligibilityCriteria":211,"healthyVolunteers":212,"sex":17,"minAge":86,"maxAge":186,"enrollmentInfo":213,"targetDuration":4,"studyType":23,"phases":214,"briefSummary":215,"conditions":216,"keywords":4,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":219,"lastUpdatePostDateStruct":220,"startDateStruct":221,"completionDateStruct":223,"leadSponsor":225,"locationsCount":47},"100640092","comparative-3-dimensional-superimposition-analysis-of-dentition-in-horizontal-and-vertical-grower-during-the-retention-phase--a-prospective-clinical-trial-100640092","NCT07622277","Comparative 3-dimensional Superimposition Analysis of Dentition in Horizontal and Vertical Grower During the Retention Phase -A Prospective Clinical Trial''","Inclusion Criteria:\n\n* Fixed orthodontic cases with FMA of 26 0 or more for hyperdivergent cases and FMA Of 24 o or less for hypodivergent cases.\n* Optimal functional occlusion at end of treatment (PAR score \\>70%).\n* Littles irregularity index (Pre-treatment \\\u003C6mm in both upper and lower arch).\n* Nonsurgical and non-orthopedic patients and non syndromic patients.\n* Optimal periodontal condition and Good oral hygiene (probing depth \\\u003C3mm, gingival index score \\\u003C1\n* Good compliance regarding retainer wear\n\nExclusion Criteria:\n\n* Subjects with incomplete orthodontic treatment.\n* TMJ disorder patients.\n* Any systemic disease affecting bone and general growth.\n* Patients with incomplete records\n* Patient who fail to follow up or undergo complete treatment.\n* Patient with learning difficulties\n* Patients having antibiotic therapy within previous 3 months and used anti inflammatory drugs in the month before the study",true,{"count":5,"type":22},[25],"This study aims to investigate the relationship between facial type and relapse of dentition post-orthodontically during the retention phase. According to the retention theorem \"teeth which have been moved through orthodontic treatment tend to naturally return to their original position. It is hypothesized that significant differences will exist in tooth movement patterns between horizontal and vertical growers, with horizontal growers exhibiting more pronounced tooth movement in the vertical plane particularly in the overbite as compared to the vertical growers . Furthermore, it is expected that facial type will influence the stability of orthodontic treatment outcomes, with long-faced individuals showing more relapse of mandibular incisor alignment and crowding. By exploring this relationship, this study aims to provide valuable insights into the factors influencing orthodontic treatment outcomes and stability. With long-faced individuals exhibiting more mandibular backward rotation and short-faced individuals showing forward rotation, which increases the risk of deep bite . Additionally, understanding these factors is crucial for orthodontists to predict and prevent potential relapse, ensuring optimal treatment results and long-term stability. Hence, the present trial will be undertaken to assess the changes and compare If there is any difference in tooth movement in 3-Dimensional superimposition in the dentition in horizontal and vertical growers post orthodontically over a period of retention phase.",[217,218],"Retention","Relapse","2026-05-30",{"date":147,"type":39},{"date":222,"type":39},"2025-02-04",{"date":224,"type":22},"2027-07",{"name":45,"class":46},{"id":227,"slug":228,"hasResults":12,"nctId":229,"briefTitle":230,"officialTitle":231,"acronym":4,"eligibilityCriteria":232,"healthyVolunteers":12,"sex":17,"minAge":160,"maxAge":57,"enrollmentInfo":233,"targetDuration":4,"studyType":140,"phases":4,"briefSummary":235,"conditions":236,"keywords":238,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":219,"lastUpdatePostDateStruct":242,"startDateStruct":244,"completionDateStruct":246,"leadSponsor":247,"locationsCount":47},"100638717","psychological-resilience-perceived-stress-and-periodontal-status-among-bruxers-100638717","NCT07615140","Psychological Resilience, Perceived Stress and Periodontal Status Among Bruxers","Psychological Resilience as a Modifier of the Relationship Between Perceived Stress and Periodontal Status Among Bruxers: a Cross-sectional Study","Inclusion Criteria:\n\n* Patients with age group 30-50 years diagnosed with generalized periodontitis.\n* Probable bruxers (as per BruxScreen questionnaire)\n* Presence of minimum 20 teeth excluding third molars\n* Able to read\u002Funderstand Hindi or English (for questionnaires)\n\nExclusion Criteria:\n\n* Systemic diseases that may affect periodontal disease progression or outcome of treatment (diabetes, autoimmune diseases)\n* History of Periodontal treatment within last 6 months\n* History of Antibiotic use within the previous 3 months\n* History of Steroid, immunosuppressive and psychiatric drug use\n* Pregnant and lactating women\n* Smoking or substance abuse",{"count":234,"type":22},75,"The present study aims to evaluate psychological resilience as a modifier of the relationship between perceived stress and periodontal status among bruxers. Given that both stress and inflammation share common neuroendocrine and immunological pathways, resilience may play a crucial role in buffering stress-induced periodontal breakdown. Understanding this relationship could shift periodontal management toward a biopsychosocial model, integrating psychological assessment and resilience enhancement with conventional non-surgical therapy. Such insights could help design personalized periodontal care strategies addressing both biological and psychological determinants of disease progression.",[29,191,237],"Perceived Stress",[239,197,240,241],"periodontitis","stress","resilience",{"date":243,"type":39},"2026-06-02",{"date":245,"type":22},"2026-06-21",{"date":77,"type":22},{"name":45,"class":46},{"id":249,"slug":250,"hasResults":12,"nctId":251,"briefTitle":252,"officialTitle":253,"acronym":4,"eligibilityCriteria":254,"healthyVolunteers":12,"sex":17,"minAge":160,"maxAge":57,"enrollmentInfo":255,"targetDuration":4,"studyType":140,"phases":4,"briefSummary":257,"conditions":258,"keywords":261,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":219,"lastUpdatePostDateStruct":265,"startDateStruct":266,"completionDateStruct":267,"leadSponsor":268,"locationsCount":47},"100638180","dental-health-state-utilities-and-oral-health-beliefs-in-periodontitis-100638180","NCT07615127","Dental Health State Utilities and Oral Health Beliefs in Periodontitis","Association of Dental Health State Utility Values and Oral Health Beliefs With Staging and Grading of Periodontitis: A Cross-sectional Evaluation","Inclusion Criteria:\n\n* Adult patients with age group 30-50 years diagnosed with generalized periodontitis.\n* Presence of minimum 20 teeth excluding third molars\n* Able to read\u002Funderstand Hindi or English (for questionnaires)\n\nExclusion Criteria:\n\n* Systemic diseases that may affect periodontal disease progression or outcome of treatment (diabetes, autoimmune diseases)\n* History of Periodontal treatment within last 6 months\n* History of Antibiotic use within the previous 3 months\n* History of Steroid, immunosuppressive and psychiatric drug use\n* Pregnant and lactating women\n* History of Smoking or substance abuse",{"count":256,"type":22},112,"This observational, cross-sectional study addresses gaps in periodontal health economics by measuring dental health state utility values (HSUVs) for periodontitis treatment. While Oral Health Related Quality of Life outcomes dominate current research, Health State Utility values are rarely measured and seldom applied . The few existing utility studies are methodologically limited. The primary aim is to measure Health state utility values for periodontal health states using direct elicitation methods ( Standard Gamble) in patients with clinically diagnosed periodontitis. The secondary aim is to examine associations between patient-elicited utility values, clinical periodontal status (CAL, PD, BoP), and psychosocial beliefs from the Health Belief Model including perceived susceptibility, severity, benefits, and barriers. Participants will complete utility tasks and Health belief model questionnaires in a single visit. By integrating preference-based utility measurement with clinical and psychosocial constructs, this study will provide essential data for cost-utility modelling of periodontal interventions and support patient-centered care.",[29,259,260],"Dental Health Utility Value","Health Belief Model",[29,262,263,264],"Denatl health state utility value","oral health beliefs","health beliefs model",{"date":243,"type":39},{"date":245,"type":22},{"date":77,"type":22},{"name":45,"class":46},{"id":270,"slug":271,"hasResults":12,"nctId":272,"briefTitle":273,"officialTitle":273,"acronym":4,"eligibilityCriteria":274,"healthyVolunteers":12,"sex":17,"minAge":86,"maxAge":4,"enrollmentInfo":275,"targetDuration":4,"studyType":23,"phases":277,"briefSummary":278,"conditions":279,"keywords":281,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":285,"lastUpdatePostDateStruct":286,"startDateStruct":288,"completionDateStruct":290,"leadSponsor":291,"locationsCount":47},"100638591","influence-of-keratinized-tissue-width-and-attached-gingiva-width-on-root-coverage-in-patients-with-recession-defects-a-prospective-clinical-study-100638591","NCT07576439","Influence of Keratinized Tissue Width and Attached Gingiva Width on Root Coverage in Patients With Recession Defects: A Prospective Clinical Study","Inclusion Criteria:\n\n1. Patients with Millers class Ⅰ and II \u002F RT1 isolated recession defects in labial maxillary and mandibular anterior teeth region.\n2. Recession depth ≥2mm\n3. Systemically healthy individuals.\n4. Age \\>18 years old.\n5. Full mouth bleeding and plaque score ≤20%\n6. Patients who agreed to participate in the study and signed an informed consent form.\n\nExclusion Criteria:\n\n1. Patients having systemic disease such as hypertension, diabetes, hyperthyroidism or on medication that influence the outcome of periodontal therapy.\n2. Patient with active periodontal disease\n3. Smokers and tobacco users\n4. Mal-aligned anterior teeth.\n5. Patients who had already undergone root coverage procedure on the selected site.\n6. Pregnant and lactating females\n7. Involved tooth with trauma from occlusion.\n8. Involved tooth with prosthesis.\n9. Endodontically involved\u002F RCT treated tooth\n10. Tooth with cervical abrasion \u002F undetectable CEJ\u002F carious",{"count":276,"type":22},30,[25],"To evaluate the association between the width of keratinized tissue and attached gingiva with root coverage outcomes in RT1 gingival recession defects of maxillary and mandibular anterior teeth treated with subepithelial connective tissue graft using a minimally invasive technique (VISTA + CTG).\n\nOBJECTIVES\n\n1. PRIMARY OBJECTIVES\n\n   1. To analyze relation and association at 3 and 6 months outcomes in terms of CRC, mRC and gingival margin position with baseline parameters including width of keratinized tissue and width of attached gingiva, after providing mucogingival plastic surgery in the form of VISTA+CTG for the treatment of RT1recession defects.\n   2. To evaluate 3 and 6 months outcomes (percentage of root coverage, width of keratinized tissue and width of attached gingiva), after providing mucogingival plastic surgery in the form of VISTA+CTG for the treatment of RT1recession defects.\n   3. To access the long-term stability of gingival margin achieved from 3 months to 6 months.\n2. SECONDARY OBJECTIVES\n\n   1. To access recession depth (RD), recession width (RW), probing pocket depth (PPD), mid buccal clinical attachment loss (bCAL), change in gingival thickness (GT) at baseline, at 3 months and 6 months.\n   2. To access patient related outcomes measures (PROM) in pain and hypersensitivity in teeth with gingival recession undergoing recession coverage.",[280],"Gingival Recessions",[282,283,284],"keratinized tissue width","attached gingiva width","RT 1 gingival recession defect","2026-05-22",{"date":287,"type":39},"2026-05-27",{"date":289,"type":22},"2026-05-01",{"date":43,"type":22},{"name":45,"class":46},{"id":293,"slug":294,"hasResults":12,"nctId":295,"briefTitle":296,"officialTitle":297,"acronym":4,"eligibilityCriteria":298,"healthyVolunteers":212,"sex":17,"minAge":86,"maxAge":4,"enrollmentInfo":299,"targetDuration":4,"studyType":23,"phases":301,"briefSummary":302,"conditions":303,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":285,"lastUpdatePostDateStruct":305,"startDateStruct":307,"completionDateStruct":308,"leadSponsor":310,"locationsCount":47},"100638511","evaluation-of-behaviour-intervention-on-adherence-and-periodontal-outcomes-100638511","NCT07614737","Evaluation of Behaviour Intervention on Adherence and Periodontal Outcomes","\"Evaluation of an Individual-centric Self-efficacy Based Behavioural Intervention on Adherence and Clinical Outcomes of Periodontal Therapy-A Randomised Controlled Trial\"","Inclusion Criteria:\n\n1. Inclusion criteria at the patient level, age ≥ 18 years\n2. According to the 2017 EFP\u002FAAP classification, patients with periodontitis stage I-III, with low self-efficacy will be included\n3. According to American Society of Anaesthesiologists Physical Status classification P1 and P2 will be included.\n\nExclusion Criteria:\n\n* Patients will be excluded from the study if they have any of the following characteristics\n\n  1. According to American Society of Anesthesiologists Physical Status classification P3 and P4 will be excluded.\n  2. Use of antibiotics within 6 months prior to the study\n  3. Xerostomia\n  4. Physical inability to perform oral hygiene procedures\n  5. Use of drugs influencing gingival hyperplasia or bleeding.\n  6. Presence of an acute condition requiring emergency dental treatment\n  7. Any periodontal treatment in the past 1 year",{"count":300,"type":22},78,[25],"Periodontitis is a chronic inflammatory disease in which long-term treatment success depends greatly on patients' adherence to oral hygiene practices and periodontal therapy. Psychological factors such as oral hygiene-related self-efficacy and illness perception may influence patients' motivation and ability to maintain effective plaque control and attend follow-up visits. However, limited evidence exists regarding the impact of behavioural interventions on adherence and clinical outcomes in periodontal therapy.\n\nThis randomized controlled trial aims to evaluate the effect of an behavioural intervention on treatment adherence and clinical periodontal outcomes in patients with Stage I-III periodontitis having low oral hygiene-related self-efficacy. A total of 78 participants will be randomized into test and control groups. Both groups will receive Step 1 and 2 periodontal therapy, including professional mechanical plaque removal and risk factor control. The test group will additionally receive a self-efficacy-based behavioural intervention while the control group will receive conventional oral hygiene instructions.\n\nClinical periodontal parameters including Turesky modification of Quigley-Hein Plaque Index (TQHI), Full Mouth Bleeding Score (FMBS), probing pocket depth (PPD), and clinical attachment level (CAL) will be assessed at baseline, 8 weeks, and 6 months. Oral hygiene self-efficacy and illness perception will also be evaluated using validated questionnaires. The primary outcomes will be treatment adherence and treatment response at 6 months. The study aims to determine whether a self-efficacy-based behavioural approach can improve adherence and enhance periodontal treatment outcomes.",[304],"Periodontitis With Low Oral Hygiene-related Self-efficacy",{"date":306,"type":39},"2026-05-29",{"date":172,"type":22},{"date":309,"type":22},"2027-09-30",{"name":45,"class":46},{"id":312,"slug":313,"hasResults":12,"nctId":314,"briefTitle":315,"officialTitle":316,"acronym":4,"eligibilityCriteria":317,"healthyVolunteers":12,"sex":17,"minAge":86,"maxAge":4,"enrollmentInfo":318,"targetDuration":4,"studyType":23,"phases":320,"briefSummary":321,"conditions":322,"keywords":4,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":285,"lastUpdatePostDateStruct":324,"startDateStruct":326,"completionDateStruct":328,"leadSponsor":329,"locationsCount":47},"100616360","responsiveness-of-hindi-version-of-oral-health-impact-profile-for-periodontitis-ohip-p-hin-100616360","NCT07304596","Responsiveness of Hindi Version of Oral Health Impact Profile for Periodontitis (OHIP-P-HIN)","Evaluation of Responsiveness of Hindi Version of Oral Health Impact Profile for Periodontitis (OHIP-P-HIN)","Inclusion Criteria:\n\n* ≥18 years of age\n* patients able to understand and complete questionnaires independently\n* confirmed diagnosis of periodontitis\n\nExclusion Criteria:\n\n* Patients with systemic diseases such as acquired immunodeficiency syndrome or diabetes mellitus\n* pregnancy\n* required prophylactic antibiotic coverage prior to dental treatment,\n* patients with bleeding disorders\n* patients who had received non-surgical periodontal therapy within the preceding eight weeks.",{"count":319,"type":22},106,[25],"The distribution- and anchor-based methods will be used to estimate the Minimal Important Difference (MID) of the OHIP-P-HIN. Two established distribution-based approaches, the standardized effect size (ES) and standardized response mean (SRM) will be calculated. The ES is calculated by dividing the mean change scores in the OHIP-P-HIN from baseline by the standard deviation of the baseline scores. And the SRM are computed as ratios of the mean change score divided by its standard deviation. The anchor-based approach will be applied by using the global transition scale as the anchor.",[29,323],"Oral Health Quality of Life (OHQoL) Was Assessed",{"date":325,"type":39},"2026-05-26",{"date":327,"type":39},"2025-11-12",{"date":151,"type":22},{"name":45,"class":46},{"id":331,"slug":332,"hasResults":12,"nctId":333,"briefTitle":334,"officialTitle":335,"acronym":4,"eligibilityCriteria":336,"healthyVolunteers":12,"sex":17,"minAge":160,"maxAge":57,"enrollmentInfo":337,"targetDuration":4,"studyType":23,"phases":338,"briefSummary":339,"conditions":340,"keywords":343,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":346,"lastUpdatePostDateStruct":347,"startDateStruct":348,"completionDateStruct":350,"leadSponsor":352,"locationsCount":47},"100591306","impact-of-periodontal-inflammation-on-allostatic-load-100591306","NCT06978712","Impact of Periodontal Inflammation on Allostatic Load","Impact of Subgingival Instrumentation on Allostatic Load in Periodontitis","Inclusion Criteria:\n\n* Patients with age group 30-50 years diagnosed with generalized periodontitis.\n* Presence of minimum 20 teeth excluding third molars.\n\nExclusion Criteria:\n\n* Periodontal treatment within last 6 months\n* History of antibiotic use within the previous 3 months\n* History of use of steroid, immunosuppressive and psychiatric drugs\n* Pregnant and lactating women\n* History of substance abuse",{"count":256,"type":22},[25],"Periodontitis is a prevalent global health issue that contributes to systemic inflammation and is closely linked to stress as a risk factor. Both conditions have been investigated for bidirectional relationship. However, the results are inconsistent, and the mechanistic links remain unclear. Allostatic load, which measures the cumulative biological effects of stress, may be relevant in elucidating this connection. Inconsistent results have been reported in previous studies exploring the association between periodontitis and individual biomarkers of allostatic load. Furthermore, none of these studies has taken into consideration staging and grading of periodontitis. Additionally, while periodontal treatment has been shown to reduce both local and systemic inflammation, its effect on allostatic load remains unexplored till date. This study aims to fill these gaps by evaluating the relationship between these parameters of periodontitis and allostatic load. Evaluation of impact of subgingival instrumentation on allostatic load may further provide insights into the broader systemic benefits of periodontal interventions.",[341,342],"Allostatic Load","Periodontitis, Chronic",[239,344,345],"inflammation","allostatic load","2026-05-21",{"date":325,"type":39},{"date":349,"type":39},"2025-06-10",{"date":351,"type":22},"2026-12-01",{"name":45,"class":46},{"id":354,"slug":355,"hasResults":12,"nctId":356,"briefTitle":357,"officialTitle":358,"acronym":4,"eligibilityCriteria":359,"healthyVolunteers":212,"sex":17,"minAge":86,"maxAge":186,"enrollmentInfo":360,"targetDuration":4,"studyType":140,"phases":4,"briefSummary":362,"conditions":363,"keywords":4,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":364,"lastUpdatePostDateStruct":365,"startDateStruct":366,"completionDateStruct":368,"leadSponsor":370,"locationsCount":47},"100635791","gingival-recession-and-oral-health-related-quality-of-life-a-cross-sectional-study-100635791","NCT07557277","Gingival Recession and Oral Health-related Quality of Life: A Cross-sectional Study","Gingival Recession and Its Impact on Oral Health-related Quality of Life: A Cross-sectional Study","Inclusion Criteria:\n\n* Age 18-45 years old;\n* Patients who are willing to participate in the study and ready to give informed consent.\n* Cases defined for GR will be done according to Cairo at el.\n* The minimum threshold for reporting the presence of gingival recession will be greater than or equal to 1 mm.\n\nExclusion Criteria:\n\n* Systemic disease affecting the periodontal issues (e.g., bleeding disorders, diabetes mellitus etc.)\n* Patients under medication associated with gingival enlargement (e.g., calcium channel blockers, immunosuppressants or anticonvulsants).\n* Patients having masochistic habits (tongue thrusting, nail biting etc.)\n* Mobile teeth\n* Involved teeth with trauma from occlusion.\n* Involved teeth with prosthesis.\n* Endodontically involved\u002F RCT treated tooth\n* Patient undergoing\u002Funderwent orthodontic treatment",{"count":361,"type":22},346,"Aim of this study is the assessment of gingival recession and its impact on oral health related quality of life in tertiary health care center in Haryana state.\n\nObjectives:\n\n1. Determine the prevalence of gingival recession (GR) through clinical screening.\n2. Classify patients with GR based on the system proposed by Cairo et al.\n3. Identify the risk factors associated with GR\n4. To assess the impact of GR on oral health related quality of life.",[63],"2026-04-22",{"date":125,"type":39},{"date":367,"type":39},"2026-03-15",{"date":369,"type":22},"2027-03-15",{"name":45,"class":46},{"id":372,"slug":373,"hasResults":12,"nctId":374,"briefTitle":375,"officialTitle":376,"acronym":4,"eligibilityCriteria":377,"healthyVolunteers":12,"sex":17,"minAge":86,"maxAge":378,"enrollmentInfo":379,"targetDuration":4,"studyType":23,"phases":381,"briefSummary":382,"conditions":383,"keywords":385,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":387,"lastUpdatePostDateStruct":388,"startDateStruct":390,"completionDateStruct":392,"leadSponsor":393,"locationsCount":47},"100624625","healing-of-apicomarginal-defects-using-autograft-or-allograft-with-collagen-membrane-100624625","NCT07412067","Healing of Apicomarginal Defects Using Autograft or Allograft With Collagen Membrane","Comparative Evaluation of Autograft and Allograft With Collagen Membrane in the Healing of Apicomarginal Defects: A Parallel-Arm Randomized Clinical Trial","Inclusion Criteria:\n\nPatients aged ≥18 years. Presence of chronic suppurative apical periodontitis with an apicomarginal defect and deep periodontal pocket, suggesting endodontic-periodontal communication up to the apex.\n\nNegative response to pulp vitality tests.\n\nExclusion Criteria:\n\nPresence of root fractures or perforations. Patients with compromised systemic health (ASA II or above). Smokers.","65 Years",{"count":380,"type":22},50,[25],"Apicomarginal defects, which connect apical and marginal bone loss, are difficult to manage surgically due to their limited regenerative potential. Guided tissue regeneration using grafts and collagen membranes may improve outcomes, but the comparative effectiveness of autografts and allografts in these defects is not well established. This randomized clinical trial at PGIDS Rohtak will evaluate 36 patients undergoing endodontic microsurgery, assigning them to either autograft or allograft combined with a bioresorbable collagen membrane. Clinical and CBCT-based radiographic healing will be monitored over 12 months. The study aims to determine whether allografts can achieve bone regeneration comparable to autografts, offering a less invasive option for treating apicomarginal defects.",[384],"Apicomarginal Defects",[386],"apicomarginal, endodontic surgery, guided tissue regeneration","2026-02-09",{"date":389,"type":39},"2026-02-17",{"date":391,"type":22},"2026-04-01",{"date":351,"type":22},{"name":45,"class":46},{"id":395,"slug":396,"hasResults":12,"nctId":397,"briefTitle":398,"officialTitle":399,"acronym":4,"eligibilityCriteria":400,"healthyVolunteers":212,"sex":17,"minAge":86,"maxAge":4,"enrollmentInfo":401,"targetDuration":4,"studyType":23,"phases":402,"briefSummary":403,"conditions":404,"keywords":406,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":387,"lastUpdatePostDateStruct":413,"startDateStruct":415,"completionDateStruct":417,"leadSponsor":419,"locationsCount":47},"100549383","comparative-evaluation-of-indirect-vs-direct-pulp-capping-in-deep-carious-mandibular-molars-100549383","NCT06433297","Comparative Evaluation of Indirect vs. Direct Pulp Capping in Deep Carious Mandibular Molars","Comparative Evaluation of Indirect and Direct Pulp Capping After Partial or Complete Caries Removal in Deeply Carious Mature Permanent Mandibular Molars With Moderate Pulpitis: A Randomized Clinical Trial","Inclusion Criteria:\n\n1. The patient should be ≥18 years of age.\n2. Restorable mature permanent 1st and 2nd Mandibular molars with deep caries (reaching inner quarter of dentine)\n3. Tooth should give positive response to pulp sensibility testing.\n4. Clinical diagnosis of moderate pulpitis.\n5. Radiographic finding of periapical index (PAI) score ≤2.\n6. Healthy periodontium (probing pocket depth ≤3 mm and mobility within normal limit).\n7. Pulp exposure after complete caries excavation.\n8. No pulp exposure after incomplete caries excavation\n\nExclusion Criteria:\n\n1. Teeth with immature roots.\n2. Pulp exposure after incomplete caries excavation.\n3. No pulp exposure after complete caries excavation.\n4. Bleeding could not be controlled in 5 minutes.\n5. Signs of pulpal necrosis, sinus tract, swelling, insufficient bleeding after pulp exposure.\n6. History of analgesic intake in previous 1 week, or antibiotic intake in 1 month.\n7. Internal\u002Fexternal resorption.\n8. Contributory medical history (alcoholism, smokers, diabetic, hypertension, drug dependency, Heart or valve disease, hepatitis, herpes, immunodeficiency (HIV), infectious diseases, kidney or liver, migraine)",{"count":319,"type":22},[25],"Aim: To compare the outcome of indirect and direct pulp capping after partial or complete caries removal in deeply carious mature mandibular permanent molars with clinical signs indicative of moderate pulpitis.\n\nObjectives:\n\n1. To evaluate the clinical and radiographic success of indirect pulp capping after partial caries removal in deeply carious mature mandibular permanent molars with clinical signs indicative of moderate pulpitis.\n2. To evaluate the clinical and radiographic success of direct pulp capping after complete caries removal in deeply carious mature mandibular permanent molars with clinical signs indicative of moderate pulpitis.\n3. To evaluate pain incidence and severity after indirect and direct pulp capping after partial and complete caries removal in deeply carious mature mandibular permanent molars with clinical signs indicative of moderate pulpitis.",[405,117],"Indirect Pulp Capping",[407,408,409,120,410,411,412],"indirect pulp capping","selective caries removal","moderate pulpitis","deep caries","complete caries removal","mature permanent mandibular molars",{"date":414,"type":39},"2026-02-12",{"date":416,"type":39},"2024-05-23",{"date":418,"type":22},"2026-03-23",{"name":45,"class":46},{"id":421,"slug":422,"hasResults":12,"nctId":423,"briefTitle":424,"officialTitle":425,"acronym":4,"eligibilityCriteria":426,"healthyVolunteers":212,"sex":17,"minAge":86,"maxAge":160,"enrollmentInfo":427,"targetDuration":4,"studyType":23,"phases":428,"briefSummary":429,"conditions":430,"keywords":4,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":432,"lastUpdatePostDateStruct":433,"startDateStruct":434,"completionDateStruct":436,"leadSponsor":438,"locationsCount":47},"100624151","evaluation-of-treatment-changes-in-class-ii-division-1-malocclusion-during-en-masse-retraction-of-upper-anterior-teeth-using-mini-implants-placed-at-infrazygomatic-crest-and-interradicular-sites-a-randomized-clinical-trial-100624151","NCT07405905","EVALUATION OF TREATMENT CHANGES IN CLASS II DIVISION 1 MALOCCLUSION DURING EN MASSE RETRACTION OF UPPER ANTERIOR TEETH USING MINI IMPLANTS PLACED AT INFRAZYGOMATIC CREST AND INTERRADICULAR SITES A RANDOMIZED CLINICAL TRIAL.","MINI IMPLANTS PLACED AT INFRAZYGOMATIC CREST VERSUS INTERRADICULAR SITES A RANDOMIZED CLINICAL TRIAL.","Inclusion Criteria:\n\n1. Non growing patients\n2. Bilateral Class II molar relationship at pre-treatment.\n3. All permanent teeth upto the second molars should be present.\n4. No or minor crowding in the maxillary arch.\n5. Horizontal to average growth pattern.\n\nExclusion Criteria:\n\n1. Subjects with a history of fixed orthodontic treatment.\n2. Crossbite\n3. Vertical growth pattern\n4. Any systemic disease affecting bone and general growth\n5. Poor oral hygiene\n6. Cleft patients\n7. Patients who fail to follow up or undergo complete treatment",{"count":276,"type":22},[25],"Rationale: Class II Division 1 malocclusion is characterized by upper anterior teeth protrusion resulting in upper lip protrusion and convex facial profile, which are considered esthetically unfavorable. Treatment of class II malocclusion due to maxillary protrusion can be done with bilateral maxillary first premolar extraction followed by en-masse retraction of upper anterior teeth using mini-implants placed at infrazygomatic or interradicular sites.\n\nAims and Objectives: To evaluate the treatment changes achieved in class II division 1 malocclusion during en- masse retraction of upper anterior teeth using mini-implants placed at infrazygomatic crest versus interradicular sites.\n\nTo compare patients' and orthodontist's perceptions of treatment being done in both the groups.\n\nMethod of study: Treatment will be initiated by bilateral maxillary 1st premolar extraction followed by bonding 0.022\" slot MBT preadjusted edgewise appliance. Maxillary arch will be stabilized with the help of 0.019\"×0.025\" stainless steel wire and then randomized allocation of the patients into 2 groups-G1 and G2 will be done. G1 will receive infrazygomatic crest mini-implants bilaterally and G2 will receive bilateral interradicular mini-implants. Hooks will be soldered on archwire used for stabilizing dentition. Ni-Ti closed coil spring will be used to apply force.",[431],"CLASS II DIVISION 1 MALOCCLUSION","2026-02-08",{"date":414,"type":39},{"date":435,"type":39},"2025-10-01",{"date":437,"type":22},"2027-02",{"name":45,"class":46},{"id":440,"slug":441,"hasResults":12,"nctId":442,"briefTitle":443,"officialTitle":444,"acronym":4,"eligibilityCriteria":445,"healthyVolunteers":12,"sex":17,"minAge":86,"maxAge":4,"enrollmentInfo":446,"targetDuration":4,"studyType":23,"phases":447,"briefSummary":448,"conditions":449,"keywords":451,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":456,"lastUpdatePostDateStruct":457,"startDateStruct":459,"completionDateStruct":461,"leadSponsor":463,"locationsCount":47},"100622282","role-of-subgingival-instrumentation-in-oral-lichen-planus-100622282","NCT07381595","Role of Subgingival Instrumentation in Oral Lichen Planus","Impact of Subgingival Instrumentation on Clinical and Immunohistochemical Presentation of Oral Lichen Planus With Gingival Involvement","Inclusion criteria:\n\n* Clinically and histopathologically confirmed cases of OLP.\n* OLP predominantly involving the gingiva.\n* Consent obtained.\n\nExclusion criteria:\n\n* Cases which does not fulfil either clinical or histopathological criteria.\n* Unwilling to participate in the study.\n* Patients with recorded history of factors that might modify immune response (such as patient on corticosteroids or medically compromised patients or suffering from heart diseases).\n* Cases undergoing treatment of OLP within past 6 months.\n* Biopsies with inadequate or non-representative samples\n* Cases histopathologically diagnosed as Lichenoid Dysplasia or Oral Lichenoid Lesions.\n* Cases diagnosed with autoimmune disorders.",{"count":276,"type":22},[25],"The goal of this interventional study is to assess the clinical and histopathological changes in Oral Lichen Planus patients with gingival involvement pre and post subgingival instrumentation.\n\nObjective- Primary objective: To observe and evaluate the clinical signs and symptoms in Oral Lichen Planus with gingival involvement. Secondary objective: To observe and evaluate the Cluster of Differentiation (CD) 4+ and 8+T lymphocytes in Oral Lichen Planus with gingival involvement.\n\nStudy group: 30 cases of Oral Lichen Planus with gingival involvement",[450],"Oral Lichen Planus",[452,453,454,455],"Subgingival instrumentation","Immunohistochemistry","CD4 and CD8 lymphocytes","Clinical parameters","2026-02-04",{"date":458,"type":39},"2026-02-06",{"date":460,"type":22},"2026-03-01",{"date":462,"type":22},"2028-12-31",{"name":45,"class":46},{"id":465,"slug":466,"hasResults":12,"nctId":467,"briefTitle":468,"officialTitle":469,"acronym":4,"eligibilityCriteria":470,"healthyVolunteers":12,"sex":17,"minAge":160,"maxAge":4,"enrollmentInfo":471,"targetDuration":4,"studyType":23,"phases":473,"briefSummary":474,"conditions":475,"keywords":478,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":483,"lastUpdatePostDateStruct":484,"startDateStruct":486,"completionDateStruct":488,"leadSponsor":490,"locationsCount":47},"100619375","the-effect-of-endodontic-treatment-on-cardiovascular-risk-biomarkers-in-patients-with-stable-coronary-artery-disease-100619375","NCT07343804","THE EFFECT OF ENDODONTIC TREATMENT ON CARDIOVASCULAR RISK BIOMARKERS IN PATIENTS WITH STABLE CORONARY ARTERY DISEASE","THE EFFECT OF ENDODONTIC TREATMENT ON CARDIOVASCULAR RISK BIOMARKERS IN PATIENTS WITH STABLE CORONARY ARTERY DISEASE : A RANDOMIZED CONTROLLED TRIAL","Inclusion Criteria:\n\n1. Individuals 30 years of age and older, with a diagnosis of stable coronary artery disease (CAD) and chronic apical periodontitis.\n2. All patients had to present with CAD defined by the Brazilian Society of Cardiology (Xavier et al., 2013) as the documented occurrence of one or more of the following events 6 months before entering the study: history of myocardial infarction, stable angina or ischaemia in non-invasive tests; surgical or percutaneous myocardial revascularization and lesion size of greater than 50% in at least one major coronary artery, as assessed by angiography; presence of angina and positive results of non-invasive testing of ischaemia.\n3. Presence of apical periodontitis defined by the presence of at least 1 radiographic radiolucency ( ≥ 3mm) in teeth as assessed both clinically and radiographically ,with periapical index (PAI) scores ≥3 in a single permanent tooth and pulp necrosis verified by cold and electric pulp test.\n\n   \\-\n\nExclusion Criteria:\n\n1. Chronic conditions associated with periodontitis or with changes in systemic inflammation (e.g. diabetes mellitus, rheumatoid arthritis, rheumatic fever, malignancy, respiratory diseases, renal diseases).\n2. Presence of localized or diffuse periodontal disease.\n3. Acute symptomatic patients\n4. Presence of CV risk factor - history of smoking\n5. Acute conditions known to affect systemic inflammatory markers (orthopaedic trauma, surgery ,viral infections)\n6. Medications (during last 3 months) known to affect systemic inflammatory markers (systemic steroids,immunosuppressants, hormone replacement therapy, contraceptives and systemic antibiotics\n7. Obesity (body mass index \\[BMI\\]≥30 kg\u002Fm2\n8. Pregnancy \\& Lactation.37",{"count":472,"type":22},80,[25],"Study subjects were obtained from the pool of OPD patients in the Department of Conservative Dentistry and Endodontics, PGIDS, Rohtak, and the Department of Cardiology, PGIMS, Rohtak. Baseline clinical, radiographic, and laboratory parameters (hsCRP and IL-6) were recorded. Patients were then randomly allocated to one of the two groups. In the test group, single-sitting root canal treatment was performed immediately, while in the control group, delayed endodontic intervention (after 3 months) was performed after three months. Clinical and laboratory parameters were again assessed at the end of 3 months in both groups. hsCRP and IL-6 indices were again done in the delayed treatment group after 3 months of root canal treatment.",[476,477],"Cardiovascular Disease Risk Factor","Periapical Periodontitis",[479,480,481,482],"cardiovascular disease","endodontic therapy","hs-CRP","IL-6","2026-01-07",{"date":485,"type":39},"2026-01-15",{"date":487,"type":39},"2025-11-01",{"date":489,"type":22},"2026-03",{"name":45,"class":46},{"id":492,"slug":493,"hasResults":12,"nctId":494,"briefTitle":495,"officialTitle":495,"acronym":4,"eligibilityCriteria":496,"healthyVolunteers":212,"sex":17,"minAge":111,"maxAge":18,"enrollmentInfo":497,"targetDuration":4,"studyType":23,"phases":499,"briefSummary":500,"conditions":501,"keywords":502,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":505,"lastUpdatePostDateStruct":506,"startDateStruct":508,"completionDateStruct":509,"leadSponsor":511,"locationsCount":47},"100616016","outcome-of-direct-pulp-capping-and-partial-pulpotomy-in-reversible-pulpitis-100616016","NCT07300124","Outcome of Direct Pulp Capping and Partial Pulpotomy in Reversible Pulpitis","Inclusion Criteria:\n\n1. Patients aged 15-40 years.\n2. Mature permanent mandibular molars with extremely deep caries on radiograph, giving positive response to pulp sensibility test.\n3. Pulpal bleeding can be controlled within 10 minutes\n4. Patients having normal periapical status with periapical index (PAI) score ≤ 2\n5. Periodontally healthy teeth\n6. Positive response to pulp sensibility test\n\nExclusion Criteria:\n\n1. Non restorable teeth\n2. Negative response to vitality testing\n3. Presence of sinus tract or soft tissue swelling\n4. Absence of deep carious lesions radiographically\n5. Radiographic signs of internal or external root resorption\n6. Patient had moderate to severe pain, but preferred root canal treatment\n7. Presence of sound dentin over pulp and pulp not exposed intraoperatively\n8. Pulp haemorrhage could not be arrested within 10 minutes.\n9. Necrotic pulp evident upon exposure\n10. Pregnant women\n11. Absence of antagonist teeth\n12. Intake of antibiotics in last 30 days",{"count":498,"type":22},138,[25],"AIM: -The aim of the study is to compare the outcome of Direct Pulp Capping and Partial Pulpotomy in mature permanent teeth with Reversible Pulpitis OBJECTIVES: - Primary Objective: to compare the difference in clinical and radiographic outcome of direct pulp capping and partial pulpotomy in mature permanent teeth with Reversible Pulpitis. Secondary objective: To evaluate and compare postoperative pain after Direct Pulp Capping and Partial Pulpotomy in teeth with Reversible Pulpitis STUDY GROUPS: - Subjects of age group 15 to 40 years will be included and divided into two groups\n\n1. Direct Pulp Capping in Permanent mature molars with Reversible Pulpitis\n2. Partial Pulpotomy in Permanent mature molars with Reversible Pulpitis",[117,118],[503,504],"Partial Pulpotomy","Direct pulp capping","2025-12-10",{"date":507,"type":39},"2025-12-23",{"date":505,"type":22},{"date":510,"type":22},"2027-12-10",{"name":45,"class":46},{"id":513,"slug":514,"hasResults":12,"nctId":515,"briefTitle":516,"officialTitle":517,"acronym":4,"eligibilityCriteria":518,"healthyVolunteers":12,"sex":17,"minAge":86,"maxAge":378,"enrollmentInfo":519,"targetDuration":4,"studyType":23,"phases":520,"briefSummary":521,"conditions":522,"keywords":4,"overallStatus":35,"whyStopped":4,"lastUpdateSubmitDate":524,"lastUpdatePostDateStruct":525,"startDateStruct":527,"completionDateStruct":529,"leadSponsor":531,"locationsCount":47},"100606767","to-evaluate-periapical-healing-post-full-pulpotomy-in-teeth-with-and-without-apical-periodontitis-100606767","NCT07179835","To Evaluate Periapical Healing Post Full Pulpotomy in Teeth With and Without Apical Periodontitis","To Evaluate Periapical Healing Post Full Pulpotomy in Permanent Mandibular Teeth With and Without Apical Periodontitis","Inclusion Criteria:\n\n1. The patient should be ≥18 years of age.\n2. Restorable mature permanent 1st and 2nd Mandibular molars with extremely deep caries (≥2\u002F3 dentine involvement)\n3. Tooth should give positive response to pulp sensibility testing.\n4. Radiographic finding of periapical index (PAI) score \\>\u002F=3 (for test group) , score \\\u003C\u002F= 2 (for control group)\n\nExclusion criteria\n\n1. Teeth with immature roots.\n2. No pulp exposure after caries excavation.\n3. Bleeding could not be controlled in 10 minutes.\n4. Signs of pulpal necrosis, sinus tract, swelling, insufficient bleeding after pulp exposure.\n5. History of analgesic intake in previous 1 week, or antibiotic intake in 1 month.\n6. Internal\u002Fexternal resorption.\n7. Contributory medical history (alcoholism, smokers, diabetic, hypertension, drug dependency, Heart or valve disease, hepatitis, herpes, immunodeficiency (HIV), infectious diseases, kidney or liver, migraine)",{"count":188,"type":22},[25],"This clinical study aims to evaluate the periapical and clinical healing outcomes of full pulpotomy using MTA in mandibular permanent molars diagnosed with symptomatic irreversible pulpitis. Patients will be stratified based on the presence or absence of apical periodontitis. Clinical and radiographic assessments will be conducted at baseline, 6 months, and 12 months to compare healing outcomes between groups. The study seeks to determine the effectiveness of full pulpotomy as a less invasive alternative to root canal treatment, even in teeth with apical pathosis.",[523],"Apical Periodontitis","2025-09-15",{"date":526,"type":39},"2025-09-18",{"date":528,"type":22},"2025-10-15",{"date":530,"type":22},"2027-10-01",{"name":45,"class":46},{"id":533,"slug":534,"hasResults":12,"nctId":535,"briefTitle":536,"officialTitle":536,"acronym":4,"eligibilityCriteria":537,"healthyVolunteers":212,"sex":17,"minAge":86,"maxAge":378,"enrollmentInfo":538,"targetDuration":4,"studyType":23,"phases":540,"briefSummary":541,"conditions":542,"keywords":4,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":544,"lastUpdatePostDateStruct":545,"startDateStruct":547,"completionDateStruct":549,"leadSponsor":551,"locationsCount":47},"100605758","effect-of-apical-third-enlargement-to-different-taper-and-master-apical-preparation-size-on-periapical-healing-and-postoperative-pain-after-primary-single-sitting-non-surgical-root-canal-treatment-100605758","NCT07166679","Effect of Apical Third Enlargement to Different Taper and Master Apical Preparation Size on Periapical Healing and Postoperative Pain After Primary Single Sitting Non Surgical Root Canal Treatment","Inclusion Criteria:\n\n1. 18-65 years of age of either sex\n2. Asymptomatic teeth having pulpal necrosis with apical periodontitis in a mandibular molar (no response to EPT or cold test)\n3. Radiographic evidence of periapical radiolucency corresponding to a periapical index (PAI) score \\>\u002F=3 in mesial root of mandibular molars\n\nExclusion Criteria:\n\n1. Patients who were medically compromised\n2. Patients with initial apical binding file (IABF) size more than 20\n3. Pregnancy; lactation \\& contraceptives.\n4. Positive history of antibiotic use within the past month or required antibiotic premedication for dental treatment (including infective endocarditis or pros thetic joint prophylaxis -",{"count":539,"type":22},270,[25],"To Determine Effect Of Apical Third enlargement To Different Taper And Master Apical Preparation Size On Periapical Healing And Postoperative Pain After Primary Single Sitting Non Surgical Root Canal Treatment : A Randomized Clinical Trial",[543],"Asymptomatic Irreversible Pulpitis","2025-09-08",{"date":546,"type":39},"2025-09-10",{"date":548,"type":39},"2025-04-18",{"date":550,"type":22},"2027-04-18",{"name":45,"class":46},{"id":553,"slug":554,"hasResults":12,"nctId":555,"briefTitle":556,"officialTitle":557,"acronym":4,"eligibilityCriteria":558,"healthyVolunteers":12,"sex":17,"minAge":86,"maxAge":19,"enrollmentInfo":559,"targetDuration":4,"studyType":23,"phases":560,"briefSummary":561,"conditions":562,"keywords":565,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":569,"lastUpdatePostDateStruct":570,"startDateStruct":572,"completionDateStruct":574,"leadSponsor":576,"locationsCount":47},"100605550","complete-pulpotomy-and-root-canal-treatment-patients-with-irreversible-pulpitis-with-type-2-diabetes-mellitus-100605550","NCT07163975","Complete Pulpotomy and Root Canal Treatment Patients With Irreversible Pulpitis With Type 2 Diabetes Mellitus","Success of Complete Pulpotomy and Root Canal Treatment and Quality of Life in Patients With Symptomatic Irreversible Pulpitis With Type 2 Diabetes Mellitus: A Randomized Clinical Trial","Inclusion Criteria:\n\n* Type 2 diabetes mellitus defined by HbA1c levels 6.5% - 8% OR FPG ≥126 mg\u002FdL OR 2-hour plasma glucose ≥200 mg\u002FdL during an OGTT OR A random plasma glucose of 200 mg\u002FdL or higher in a patient with classic symptoms of hyperglycemia or hyperglycemic crisis\n* Age between 18 - 70 years.\n* Permanent mandibular posterior teeth with clinical and radiographic signs and symptoms indicative of irreversible pulpitis (PAI score ≤2)\n* Tooth showing positive response to pulp sensibility testing with no tenderness on percussion.\n* BMI\\\u003C30 Kg\u002Fm2\n\nExclusion Criteria:\n\n* Patients with immunocompromised diseases or chronic kidney disease\n* Smokers, pregnant and lactating women\n* Teeth with immature roots or retained deciduous tooth.\n* Bleeding could not be controlled in ≥5 minutes.\n* Tooth with signs and symptoms of apical periodontitis.\n* Teeth with procedural errors, cracks, fractured teeth\n* Tooth with probing depth more than 4mm.\n* Positive history of antibiotic use in the past 1 month or requiring antibiotic prophylaxis and\u002For analgesic usage in past 3 days.\n* Patients taking drugs that affect bone metabolism such as immune- suppressants, SSRIs, bisphosphonates, hormone replacement therapy",{"count":319,"type":22},[25],"there is limited endodontic research on the effects of DM on pulp tissues. Diabetic human and animal histological research have demonstrated decreased wound repair, chronic pulp inflammation and reduced dentin bridge formation. To date, no human clinical trial has examined the impact of diabetes mellitus on teeth with irreversible pulpitis. Due to the paucity of data in the literature, there is a clinical dilemma whether to recommend root canal therapy or vital pulp therapy in diabetic patients with irreversible pulpitis.\n\nTo the best of our knowledge, no prospective study has evaluated the outcome of complete pulpotomy versus root canal treatment in T2DM patients with irreversible pulpitis. The aim of this study is to compare and evaluate the success rates of pulpotomy and root canal treatment in type 2 diabetes mellitus patients in mature permanent teeth presenting with clinical symptoms of irreversible pulpitis.",[563,564],"Type 2 Diabetes Mellitus (T2DM)","Irreversible Pulpitis",[566,567,568],"pulpotomy","type 2 Diabetes Mellitus","irreversible pulpitis","2025-09-05",{"date":571,"type":39},"2025-09-09",{"date":573,"type":39},"2025-05-01",{"date":575,"type":22},"2027-05-01",{"name":45,"class":46},{"id":578,"slug":579,"hasResults":12,"nctId":580,"briefTitle":581,"officialTitle":582,"acronym":4,"eligibilityCriteria":583,"healthyVolunteers":212,"sex":17,"minAge":86,"maxAge":4,"enrollmentInfo":584,"targetDuration":4,"studyType":23,"phases":586,"briefSummary":587,"conditions":588,"keywords":591,"overallStatus":70,"whyStopped":4,"lastUpdateSubmitDate":569,"lastUpdatePostDateStruct":595,"startDateStruct":597,"completionDateStruct":598,"leadSponsor":599,"locationsCount":47},"100605958","impact-of-dme-on-pulpal-and-periodontal-health-at-varying-gingival-seat-level-100605958","NCT07169305","Impact of DME on Pulpal and Periodontal Health at Varying Gingival Seat Level","Impact of DME on Pulpal and Periodontal Health at Varying Gingival Seat Level in Class II Subgingival Composite Restorations","Inclusion Criteria:\n\n* Patients at least 18 years of age at the time of treatment.\n\n  * Permanent Posterior teeth exhibiting proximal caries lesion extending subgingivally below the cemento-enamel junction (CEJ). The axial extent of the caries should not be more than 75% of the dentin thickness.\n  * Sound tooth structure of atleast 1mm should be present from the alveolar crest to the base of the cavity\u002F gingival seat after cavity preparation.\n  * The tooth should either be asymptomatic or have reversible pulpitis as determined by history and pulp sensibility testing. There should be no history of spontaneous or lingering pain\n  * Periodontally sound tooth\n  * Full mouth plaque score (FMPS): ≤ 15% and Full mouth bleeding score (FMBS): ≤15%\n\nExclusion Criteria:\n\n* Presence of bone disease (metabolic, endocrine, infectious, tumoral, developmental pathologies)\n\n  * Pregnant or lactating and history of smoking or alcohol abuse\n  * Anti inflammatory drug consumption within past 3 days\n  * Uncontrolled or poorly controlled diabetes\n  * Unstable Life threatening conditions or requiring antibiotic prophylaxis.\n  * Presence of detectable plaque and Bleeding on probing on the tooth to be treated\n  * Thin gingival biotype, Periodontitis and Gingival recession\n  * Class II cavities with gingival margin above the CEJ\n  * Previously restored teeth\n  * Absence of adjacent tooth or antagonist or Crown in adjacent tooth.\n  * H\u002Fo Bruxism, Xerostomia\n  * Requiring gingivectomy\n  * Isolation with rubber dam not possible",{"count":585,"type":22},81,[25],"The classical idea was to keep the biologic width untouched in order to maintain periodontal health but the newer case reports have given a new dimension to this concept, stating that a limited extension into STA can be used as an alternative for invasive procedures like SCL. The periodontal tissues can still tolerate subgingival margin placement in biologic width when restorations are free of overhangs which are real culprit for providing room for plaque retention and further inflammation. There are no sufficient clinical studies with good sample size to prove the significance of this concept. Hence, we are performing a Non Randomized Controlled trial by placing gingival margins at various levels above the alveolar crest and restoring it with composite and further evaluate the periodontal tissue health, pulpal health, restoration quality and significance of DME.",[589,590],"Deep Margin Elevation","Pulpal and Periodontal Health",[592,593,594],"Deep margin elevation","Pulpal and Periodontal health","Class II Composite restorations",{"date":596,"type":39},"2025-09-11",{"date":573,"type":39},{"date":575,"type":22},{"name":45,"class":46},""]