[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"health-studies-list:{\"overallStatus\":[\"RECRUITING\",\"AVAILABLE\",\"NOT_YET_RECRUITING\"],\"leadSponsorName\":\"Poznan University of Physical Education\",\"orderBy\":\"LastUpdateSubmitDate:desc\",\"size\":25,\"offset\":0}":3,"health-study-condition:":355},{"pageToken":4,"total":5,"offset":6,"count":5,"results":7},null,12,0,[8,50,84,107,126,155,189,218,249,278,304,330],{"id":9,"slug":10,"hasResults":11,"nctId":12,"briefTitle":13,"officialTitle":14,"acronym":4,"eligibilityCriteria":15,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":18,"enrollmentInfo":19,"targetDuration":4,"studyType":22,"phases":23,"briefSummary":25,"conditions":26,"keywords":28,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":38,"lastUpdatePostDateStruct":39,"startDateStruct":42,"completionDateStruct":44,"leadSponsor":46,"locationsCount":49},"100641610","longitudinal-stripping-massage-vs-percussion-device-for-neck-pain-ultrasound-study-100641610",false,"NCT07630142","Longitudinal Stripping Massage vs. Percussion Device for Neck Pain: Ultrasound Study.","The Effect of Percussion Therapy on Neck Functional Disability, Pain and Upper Trapezius Muscle Properties Assessed by Elastography and Doppler Ultrasound in Patients With Neck Pain.","Inclusion Criteria:\n\n* Age: 18-60 years\n* Neck pain persisting for at least 3 months\n* Visual Analog Scale (VAS) score between 3 and 7\n* Neck Disability Index (NDI) between 30% and 48%\n\nExclusion Criteria:\n\n* Pregnancy and postpartum period\n* History of cervical spine or shoulder surgery\n* Diagnosed fibromyalgia, radiculopathy, or myelopathy\n* Myofascial therapy within the last 3 months\n* Use of analgesic medication within 48 hours before assessment\n* Venous diseases","ALL","18 Years","60 Years",{"count":20,"type":21},35,"ESTIMATED","INTERVENTIONAL",[24],"NA","This study evaluates whether a single session of percussion therapy can reduce muscle tension and increase blood flow in the transverse cervical artery in individuals with neck pain. The investigators will evaluate muscle stiffness using ultrasound elastography, and assess blood flow in the transverse cervical artery via Doppler imaging before and after treatment. The primary objective is to determine how this therapy affects neck muscle relaxation and vascular responses, specifically within the upper trapezius region.",[27],"Chronic Neck Pain",[29,30,31,32,33,34,35,36],"neck pain","longitudinal stripping massage","percussion massage","trapezius","elastography","shear wave","Doppler ultrasound","cervical pain","RECRUITING","2026-06-14",{"date":40,"type":41},"2026-06-17","ACTUAL",{"date":43,"type":21},"2026-06-01",{"date":45,"type":21},"2029-06-01",{"name":47,"class":48},"Poznan University of Physical Education","OTHER",1,{"id":51,"slug":52,"hasResults":11,"nctId":53,"briefTitle":54,"officialTitle":55,"acronym":4,"eligibilityCriteria":56,"healthyVolunteers":57,"sex":16,"minAge":58,"maxAge":59,"enrollmentInfo":60,"targetDuration":62,"studyType":63,"phases":4,"briefSummary":64,"conditions":65,"keywords":67,"overallStatus":75,"whyStopped":4,"lastUpdateSubmitDate":76,"lastUpdatePostDateStruct":77,"startDateStruct":79,"completionDateStruct":81,"leadSponsor":83,"locationsCount":4},"100637772","multilevel-exercise-response-in-rowers-100637772","NCT07613619","Multilevel Exercise Response in Rowers","Multilevel Assessment of Physiological, Molecular, Metabolic, Intestinal, and Psychophysiological Responses to Rowing Ergometer Exercise in Competitive Rowers","Inclusion Criteria:\n\n* Male and female members of the Polish Youth National Rowing Team.\n* Age between 19 and 24 years.\n* Regular participation in structured rowing training.\n* Medical clearance for participation in maximal exercise testing.\n* Ability and willingness to provide written informed consent.\n\nExclusion Criteria:\n\n* Lack of consent for blood sampling or study participation.\n* Current injury or health condition contraindicating maximal exercise.\n* Acute infection, fever, or inflammatory condition at the time of testing.\n* Use of anti-inflammatory medications.\n* Use of performance-enhancing substances.\n* Use of dietary supplements within 3 months before study participation.\n* Any medical contraindications identified by the study physician.",true,"19 Years","24 Years",{"count":61,"type":21},30,"6 Months","OBSERVATIONAL","This observational study aims to evaluate multilevel physiological, molecular, metabolic, intestinal, immunological, and psychophysiological responses to rowing-specific exercise in elite rowers. The study is designed to investigate how maximal and prolonged rowing ergometer exercise influences integrated adaptive mechanisms related to mitochondrial function, metabolic regulation, intestinal permeability, immune activation, DNA damage response, and psychological status.\n\nThirty members of the Polish Youth National Rowing Team, aged 19-24 years, will participate in the study during two different training periods. During the competitive phase, participants will perform a 2000-m maximal rowing ergometer test, whereas during the preparatory phase they will complete a 6000-m rowing ergometer test. Blood samples and physiological measurements will be collected before exercise, immediately after exercise, and after 1 hour of recovery.\n\nThe study will assess gene expression, circulating biomarkers, flow cytometry parameters, blood morphology, lactate concentration, continuous glucose monitoring data, wearable metabolic sensor measurements, nutritional status, and psychological responses. The primary objective is to identify integrated biomarkers reflecting exercise load, recovery dynamics, and adaptive capacity in highly trained athletes. The study also aims to improve understanding of the interaction between metabolic, mitochondrial, intestinal, immunological, and psychophysiological responses to intensive exercise in rowing.",[66],"Healthy Adult Participants",[68,69,70,71,72,73,74],"Rowing","Exercise physiology","Mitochondrial function","Intestinal permeability","DNA damage response","Psychophysiology","Elite athletes","NOT_YET_RECRUITING","2026-05-21",{"date":78,"type":41},"2026-05-29",{"date":80,"type":21},"2026-05-17",{"date":82,"type":21},"2027-01-30",{"name":47,"class":48},{"id":85,"slug":86,"hasResults":11,"nctId":87,"briefTitle":88,"officialTitle":89,"acronym":4,"eligibilityCriteria":90,"healthyVolunteers":11,"sex":91,"minAge":17,"maxAge":92,"enrollmentInfo":93,"targetDuration":4,"studyType":22,"phases":94,"briefSummary":95,"conditions":96,"keywords":4,"overallStatus":75,"whyStopped":4,"lastUpdateSubmitDate":99,"lastUpdatePostDateStruct":100,"startDateStruct":102,"completionDateStruct":104,"leadSponsor":106,"locationsCount":49},"100626607","psychophysiological-responses-to-six-single-session-self-regulation-interventions-in-a-female-adult-with-adhd-and-stabilized-bipolar-disorder-100626607","NCT07437833","Psychophysiological Responses to Six Single-Session Self-Regulation Interventions in a Female Adult With ADHD and Stabilized Bipolar Disorder","Psychophysiological Responses to Six 15-Minute Single-Session Self-Regulation Interventions in a Female Adult With ADHD and Stabilized Bipolar Disorder: A Single-Case Study","Inclusion Criteria:\n\n* Diagnosis of ADHD and bipolar disorder (type I or II) in stable remission.\n* No active depressive, manic, or psychotic episodes for at least 2 years.\n* No use of psychotropic medications, including mood stabilizers, antidepressants, antipsychotics, or ADHD medications, for at least 2 years.\n* No chronic somatic diseases (including neurological, cardiovascular, or metabolic disorders).\n* Regular sleep-wake rhythm during the week preceding the study.\n* Non-smoker.\n* No night-shift work in the week preceding the study.\n\nExclusion Criteria:\n\n* Acute medical conditions that could affect study procedures.\n* Use of medications in the past 3 months that influence cardiovascular or neurological parameters.\n* Consumption of alcohol or psychoactive substances on the day before or day of the study.\n* Intense physical activity on the day before or day of the study.\n* Contraindications to moderate-intensity exercise on a cycle ergometer (e.g., recent injuries, chronic musculoskeletal conditions).\n* Contraindications to EEG measurement (e.g., scalp skin conditions preventing proper electrode placement, hypersensitivity to conductive gels or pastes).","FEMALE","35 Years",{"count":49,"type":21},[24],"This study aims to explore how six short, 15-minute self-regulation techniques affect the body and brain in a female adult with ADHD and stabilized bipolar disorder. The techniques being tested include:\n\n* Aerobic exercise\n* Controlled breathing (cyclic sighing)\n* Aromatherapy with lavender essential oil\n* Listening to specific music (Solfeggio 528 Hz)\n* Virtual reality relaxation with forest imagery\n* Emotional Freedom Technique (EFT) tapping One session of quiet sitting with eyes open serves as a comparison.\n\nThe participant will attend one 15-minute session per week for each technique. Before and after each session, the researchers will measure:\n\n* Heart rate and heart rate variability\n* Stress levels using Subjective Units of Distress Scale\n* Mood using a questionnaire\n* Blood pressure\n* Brain activity using EEG\n* Memory performance with a simple test (N-back)\n* Pain sensitivity The goal is to understand how these short, non-invasive techniques influence both physiological and psychological responses. Sessions are safe, short, and designed to involve minimal risk. The findings may help guide future research on relaxation and exercise strategies for people with ADHD and bipolar disorder.",[97,98],"ADHD - Attention Deficit Disorder With Hyperactivity","Bipolar Affective Disorder; Remission in","2026-02-23",{"date":101,"type":41},"2026-02-27",{"date":103,"type":21},"2026-04-01",{"date":105,"type":21},"2026-08-31",{"name":47,"class":48},{"id":108,"slug":109,"hasResults":11,"nctId":110,"briefTitle":111,"officialTitle":112,"acronym":4,"eligibilityCriteria":113,"healthyVolunteers":57,"sex":16,"minAge":17,"maxAge":92,"enrollmentInfo":114,"targetDuration":4,"studyType":22,"phases":115,"briefSummary":116,"conditions":117,"keywords":4,"overallStatus":75,"whyStopped":4,"lastUpdateSubmitDate":119,"lastUpdatePostDateStruct":120,"startDateStruct":122,"completionDateStruct":124,"leadSponsor":125,"locationsCount":4},"100622129","effects-of-moderate-exercise-and-cyclic-sighing-on-stress-cognition-and-physiological-markers-in-young-adults-100622129","NCT07379606","Effects of Moderate Exercise and Cyclic Sighing on Stress, Cognition and Physiological Markers in Young Adults","A Comparison of Psychophysiological Effects Between Relaxation Techniques and Physical Exercise in Young Adults","Inclusion Criteria:\n\n* male or female participants,\n* age 18-35,\n* without chronic somatic diseases,\n* no current episode of psychiatric disorder (no active depression, mania, or psychosis),\n* regular sleep schedule in the week prior to the study,\n* not taking psychotropic drugs or medications,\n* non-smoker,\n* not working nightshifts.\n\nExclusion Criteria:\n\n* consumption of alcohol or psychoactive substances the day before or on the day of the study,\n* intense physical activity less than 2 hours before the study,\n* consuming coffee, black tee, energy drinks less than 2 hours before the study,\n* contraindications to moderate-intensity physical activity on cycle ergometer (e.g., recent injuries),\n* contraindications to EEG (e.g., scalp skin conditions preventing proper electrode placement, hypersensitivity to conductive gels or pastes).",{"count":61,"type":21},[24],"This study investigates the effects of moderate physical exercise and cyclic sighing (breathing training) on stress, cognition, and physiological markers in young adults. It is a randomized cross-over trial with two interventions. Each participant will take part in two intervention sessions:\n\n1. Moderate-intensity physical activity (PA): 15 minutes of stationary cycling at 65-75% of maximum heart rate (HRmax).\n2. Breathing training (CS): 15 minutes of cyclic sighing, a technique involving inhaling, pausing briefly, taking a deeper breath, and exhaling slowly.\n\nA one-week washout period between sessions is planned to minimise carry-over effects and to ensure participants' physiological state is similar before the next session. During this week, participants will wear Polar Ignite wrist-worn devices to monitor physical activity and sleep.\n\nA total of 30 participants (you adults) will be enrolled.\n\nMeasurements performed before and after each intervention include:\n\n* EEG using Emotiv EPOC Flex Gel (32-channel device): 2 minutes with eyes open, 2 minutes with eyes closed, during the interventions, and while performing cognitive test (N-back).\n* Heart rate variability (HRV) using the Polar H10 sensor.\n* SUDS - Subjective Units of Disress Scale for perceived stress.\n* N-back test for cognitive performance using Emotiv App.\n* Blood pressure (systolic and diastolic) and heart rate.\n* Pain threshold measured with a dolorimeter.\n* PANAS-SF - Positive and Negative Affect Schedule.\n\nBaseline questionnaires completed by participants the day before the study:\n\n* PSS-10 - Perceived Stress Scale (Cohen, Kamarck, Mermelstein).\n* MAAS - Mindful Attention Awareness Scale\n* Psychological well-being - short version\n* Mini-COPE - Coping with Stress Inventory\n* Sleep quality and average sleep duration\n* Chronotype questionnaire (morningness-eveningness)\n* GPAQ - Global Physical Activity Questionnaire\n* Pittsburgh Sleep Quality Index\n\nThe study aims to understand how brief interventions like moderate exercise and breathing techniques affect stress, cognitive performance, and physiological responses in young adults.",[118],"Stress","2026-01-23",{"date":121,"type":41},"2026-01-30",{"date":123,"type":21},"2026-03-01",{"date":105,"type":21},{"name":47,"class":48},{"id":127,"slug":128,"hasResults":11,"nctId":129,"briefTitle":130,"officialTitle":131,"acronym":4,"eligibilityCriteria":132,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":133,"enrollmentInfo":134,"targetDuration":4,"studyType":22,"phases":136,"briefSummary":137,"conditions":138,"keywords":141,"overallStatus":75,"whyStopped":4,"lastUpdateSubmitDate":147,"lastUpdatePostDateStruct":148,"startDateStruct":150,"completionDateStruct":152,"leadSponsor":154,"locationsCount":4},"100610842","cytokines-neuroplasticity-modulators-and-biomarkers-in-spinal-canal-stenosis-and-endoscopic-decompression-100610842","NCT07232836","Cytokines, Neuroplasticity Modulators, and Biomarkers in Spinal Canal Stenosis and Endoscopic Decompression","The Role of Cytokines and Neuroplasticity Modulators in the Development of Spinal Canal Stenosis and the Identification of Biomarkers for the Biochemical Evaluation of Treatment in Patients Undergoing Endoscopic Spinal Canal Decompression","Inclusion Criteria for the experimental group:\n\n1. Spinal stenosis in the lumbar spine with a referral for surgical treatment using endoscopic spinal decompression.\n2. Age: 40-90 years.\n3. Current MRI results.\n4. Consent to participate in the study.\n\nInclusion Criteria for the control no spinal stenosis group:\n\n1. Intervertebral disc herniation in the lumbar spine with a referral for surgical treatment using endoscopic discectomy.\n2. Age: 18-40 years.\n3. Current MRI results.\n4. Consent to participate in the study.\n\nExclusion Criteria:\n\nHistory of:\n\n* rheumatoid arthritis of the intervertebral joints,\n* joint pain located elsewhere if it is more severe than the pain caused by stenosis,\n* pathologies and\u002For medications that may disturb the balance between pro- and anti-inflammatory factors (e.g. inflammatory diseases, rheumatoid arthritis, ankylosing spondylitis, acute infection),\n* uncontrolled diabetes, poorly controlled hypertension, clinically significant liver function impairment, acute coronary event, unstable angina pectoris, symptoms of heart failure, pacemaker implantation,\n* neurological diseases within the last 6 months,\n* previous spine surgery at the lumbar level,\n* mechanical injuries to the spine after an accident,\n* advanced osteoporosis,\n* pregnancy, lactation.","90 Years",{"count":135,"type":21},100,[24],"Research Rationale and Study Design Lumbar spinal stenosis (LSS) is a common degenerative musculoskeletal disorder characterized by narrowing of the spinal canal, often leading to pain and disability. One of the primary contributors to this condition is hypertrophy (thickening) of the ligamentum flavum (LF), along with facet joint degeneration, intervertebral disc herniation, and ligament ossification. However, the pathophysiological mechanisms behind these changes remain incompletely understood.\n\nHistological changes in hypertrophied LF include fibrocartilaginous metaplasia, type II collagen proliferation, ossification, calcium crystal deposition, and degeneration of elastic and collagen fibers. Both mechanical stress and inflammatory processes, particularly macrophage infiltration, are considered key contributors to degeneration, especially in the aging population. Yet, inflammation linked to systemic metabolic disorders-such as obesity and sarcopenia-may also significantly influence the degeneration of spinal structures.\n\nMetabolic Inflammation and the Role of Adipokines Recent research has highlighted the role of adipokines in the pathogenesis of degenerative spinal and joint diseases. Disrupted lipid metabolism and chronic low-grade inflammation contribute to tissue remodeling, extracellular matrix (ECM) degradation, and ectopic fat deposition in spinal structures.\n\nEpidural fat, normally present in the spinal canal, can become inflamed and secrete pro-inflammatory cytokines, potentially affecting adjacent tissues such as muscles and ligaments. Conditions like spinal epidural lipomatosis, which is associated with obesity, exemplify this pathological mechanism.\n\nWhile adipokines like leptin and visfatin have been previously associated with LF ossification and degeneration, the presence and role of others-such as adipsin, vaspin, resistin, lipocalin-2, progranulin, chemerin, omentin-1, and GDF-15-have not yet been studied in LF or epidural fat. Given their known effects on inflammation and ECM remodeling, these molecules are strong candidates for involvement in spinal canal narrowing.\n\nResearch Hypotheses and Objectives\n\nThis study hypothesizes that adipose tissue-derived cytokines, particularly from epidural fat, contribute to LF degeneration and LSS through inflammatory and metabolic signaling. The main research objectives are to:\n\n1. Identify differences in biomarker concentrations in LF, paraspinal muscle, and epidural fat from patients with and without LSS.\n2. Determine correlations between tissue and blood biomarker levels and clinical parameters such as pain, disability, and body mass.\n3. Select potential biomarkers for monitoring surgical outcomes of spinal decompression.\n4. Identify cytokines that modulate LF inflammation and metabolism.\n5. Evaluate the direct effects of adipokines on LF cell behavior in vitro. Study Design and Methods\n\n   Study population:\n\n   • 100 patients undergoing lumbar spine surgery at the Orthopaedic-Rehabilitation Clinical Hospital in Poznań:\n\n   o 50 with LSS (ages 40-90)\n   * 50 with disc herniation only (ages 18-40; control group)\n\n   Tissue collection (intraoperative):\n\n   • Ligamentum flavum\n\n   • Paraspinal muscles\n\n   • Epidural adipose tissue\n\n   Blood samples:\n\n   • Collected from all participants:\n\n   o Within 48 hours before surgery\n\n   o Two months post-surgery\n\n   Clinical assessments:\n\n   • Disability and pain scales\n   * Preoperative MRI scans\n\n   Laboratory analysis:\n\n   • Molecular testing:\n   * mRNA expression of selected cytokines and adipokines using PCR\n   * Protein levels determined via ELISA in both serum and tissue homogenates • Cell culture studies:\n   * One-third of collected tissue is used to establish primary cell cultures from LF, paraspinal muscles, and epidural fat\n   * Cells will be stimulated with conditioned media from epidural fat and with selected recombinant cytokines (e.g., vaspin, lipocalin-2, GDF-15)\n   * Experiments will assess the gene and protein expression of key molecules involved in inflammation, ECM remodeling, bone metabolism, fibrosis, and matrix degradation.\n\n   The goal is to clarify the local and systemic roles of adipokines and inflammation in the pathogenesis of LF hypertrophy and LSS. This knowledge may aid in identifying biomarkers for disease progression and therapeutic targets for non-surgical interventions in the future.",[139,140],"Spinal Stenosis","Ligamentum Flavum Hypertrophy",[142,143,144,145,146],"adipokines","biomarkers","endoscopic spinal canal decompression","inflammation","epidural adipose tissue","2025-11-15",{"date":149,"type":41},"2025-11-18",{"date":151,"type":21},"2025-11-17",{"date":153,"type":21},"2030-12-31",{"name":47,"class":48},{"id":156,"slug":157,"hasResults":11,"nctId":158,"briefTitle":159,"officialTitle":160,"acronym":4,"eligibilityCriteria":161,"healthyVolunteers":57,"sex":91,"minAge":162,"maxAge":163,"enrollmentInfo":164,"targetDuration":4,"studyType":22,"phases":165,"briefSummary":167,"conditions":168,"keywords":172,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":181,"lastUpdatePostDateStruct":182,"startDateStruct":184,"completionDateStruct":186,"leadSponsor":188,"locationsCount":49},"100600087","phase-3-effects-of--alanine-and-sodium-bicarbonate-supplementation-on-physical-capacity-and-biochemical-markers-concentrations-100600087","NCT07092930","Effects of β-alanine and Sodium Bicarbonate Supplementation on Physical Capacity and Biochemical Markers Concentrations","Evaluation of the Synergistic Effect of β-alanine and Sodium Bicarbonate Supplementation on Physical Capacity and Blood Biochemical Markers Concentrations in Trained Female Basketball Players","Inclusion Criteria:\n\n* written consent to participate,\n* general good health condition,\n* a current medical clearance to practice sports,\n* training experience: at least 4 years,\n* minimum of 4 workout sessions (in the discipline covered by the study) a week.\n\nExclusion Criteria:\n\n* current injury,\n* any health-related contraindication,\n* declared general feeling of being unwell,\n* taking supplements, especially ergogenic supplements that modulate extra- and intracellular capacity 3 months prior to research (except taking protein and\u002For carbohydrate powders, isotonic drinks),\n* unwilling to follow the study protocol.","16 Years","40 Years",{"count":135,"type":21},[166],"PHASE3","This randomized, double-blind, placebo-controlled, parallel-group study aims to evaluate the potential synergistic effect of beta-alanine (BA) and sodium bicarbonate (SB) supplementation, compared to their separate administration or placebo (PL), on physical performance and selected blood biochemical markers in highly trained female basketball players.",[169,170,171],"Supplementation","Sports","Female Athletes",[173,174,175,176,177,178,179,180],"Beta-alanine","Sodium bicarbonate","Ergogenic aids","Sports nutrition","Team sports","Physical capacity","Body composition","Blood and urine biochemical markers","2025-07-28",{"date":183,"type":41},"2025-07-30",{"date":185,"type":41},"2023-10-01",{"date":187,"type":21},"2025-12",{"name":47,"class":48},{"id":190,"slug":191,"hasResults":11,"nctId":192,"briefTitle":193,"officialTitle":193,"acronym":4,"eligibilityCriteria":194,"healthyVolunteers":57,"sex":16,"minAge":195,"maxAge":196,"enrollmentInfo":197,"targetDuration":4,"studyType":22,"phases":199,"briefSummary":200,"conditions":201,"keywords":4,"overallStatus":75,"whyStopped":4,"lastUpdateSubmitDate":210,"lastUpdatePostDateStruct":211,"startDateStruct":213,"completionDateStruct":215,"leadSponsor":217,"locationsCount":49},"100587274","effects-of-vr-based-respiratory-training-on-motor-reaction-time-and-correctness-stress-levels-attention-motor-skills-postural-stability-and-sleep-quality-in-shift-healthcare-workers-100587274","NCT06926257","Effects of VR-based Respiratory Training on Motor Reaction Time and Correctness, Stress Levels, Attention, Motor Skills, Postural Stability and Sleep Quality in Shift Healthcare Workers","The study will be conducted in a group of paramedics and nurses of both sexes, aged 23-45. It is expected that 60 people will be examined. The study will include hospital emergency department employees, working shifts, with a minimum of two years of work experience. Those who receive a doctor's consent to participate in the study and give informed consent will be admitted to the study.","23 Years","45 Years",{"count":198,"type":21},60,[24],"This study investigates the effects of virtual reality (VR)-based respiratory training on various physiological and cognitive functions in shift-working healthcare professionals, including paramedics and nurses. The research will evaluate how VR-guided breathing exercises influence: stress levels, motor reaction time and accuracy, attention and cognitive performance, motor skills and postural stability, sleep quality\n\nParticipants will be divided into three groups:\n\nVR-based respiratory training group - performing guided breathing exercises in a VR environment.\n\nMusic-based relaxation group - listening to relaxing music without structured breathing instructions.\n\nControl group - no intervention.\n\nThe findings will help determine whether VR-based respiratory training is an effective method for improving stress resilience, cognitive function, and physical performance in shift-working healthcare professionals.",[202,203,204,205,206,207,208,209],"Healthcare Workers","Stress Level","Emergency Department","Shift Work Sleep Disorder","Postural Stability","VR Breathing Exercises","Attention","Time Reaction","2025-04-11",{"date":212,"type":41},"2025-04-13",{"date":214,"type":21},"2025-04-07",{"date":216,"type":21},"2025-12-30",{"name":47,"class":48},{"id":219,"slug":220,"hasResults":11,"nctId":221,"briefTitle":222,"officialTitle":222,"acronym":223,"eligibilityCriteria":224,"healthyVolunteers":57,"sex":16,"minAge":17,"maxAge":133,"enrollmentInfo":225,"targetDuration":4,"studyType":22,"phases":227,"briefSummary":228,"conditions":229,"keywords":237,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":241,"lastUpdatePostDateStruct":242,"startDateStruct":244,"completionDateStruct":246,"leadSponsor":248,"locationsCount":49},"100584618","use-of-tdcs-stimulation-in-neurological-and-gynaecological-conditions-100584618","NCT06891690","Use of TDCS Stimulation in Neurological and Gynaecological Conditions","tDCS","Neurological patients\n\nInclusion Criteria:\n\n* impairment of upper and lower limb function.\n\nExclusion Criteria:\n\n* no written consent to participate in the study.\n\nGynaecological patients\n\nInclusion Criteria:\n\n* women with selected gynaecological conditions (endometriosis, painful menstruation, dyspareunia, polycystic ovary syndrome) with no treatment other than tDCS stimulation.\n\nExclusion Criteria:\n\n* no written consent to participate in the study.",{"count":226,"type":21},300,[24],"The aim of the study is to test the effect of tDCS stimulation on upper and lower limb function in neurological patients and to reduce pain in gynaecological patients. And the impact of tDCS stimulation on patients' quality of life. Standardised questionnaires will be used for pre- and post-stimulation evaluation.",[230,231,232,233,234,235,236],"Stroke","Spinal Cord Diseases","Nerve Root Disorder","Endometriosis","Dyspareunia","Painful Menstruation","Polycystic Ovary",[238,239,240],"tDCS stimulation","quality of life","pain","2025-03-17",{"date":243,"type":41},"2025-03-24",{"date":245,"type":41},"2025-02-05",{"date":247,"type":21},"2025-12-31",{"name":47,"class":48},{"id":250,"slug":251,"hasResults":11,"nctId":252,"briefTitle":253,"officialTitle":254,"acronym":255,"eligibilityCriteria":256,"healthyVolunteers":11,"sex":91,"minAge":17,"maxAge":18,"enrollmentInfo":257,"targetDuration":4,"studyType":22,"phases":259,"briefSummary":260,"conditions":261,"keywords":264,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":245,"lastUpdatePostDateStruct":271,"startDateStruct":273,"completionDateStruct":275,"leadSponsor":277,"locationsCount":49},"100514432","functional-links-between-the-temporomandibular-joint-and-the-pelvis-in-gynecology-100514432","NCT05978414","Functional Links Between the Temporomandibular Joint and the Pelvis in Gynecology","Functional Relationships Between the Temporomandibular Joint and the Pelvis in Women With Gynecological Diseases of Genital Prolapse and Endometriosis","TMJ and Pelvis","Inclusion Criteria:\n\n1. Written consent to participate in the study.\n2. Female patients after surgical treatment with prolapse of reproductive organs and diagnosed endometriosis.\n\nExclusion Criteria:\n\n1. No written consent to participate in the study.\n2. Cancer.\n3. Injury to the temporomandibular joint and pelvis.\n4. Fibromyalgia.\n5. Rheumatic diseases.\n6. At each stage of the experiment if the patient decides that she does not want to participate she is excluded.",{"count":258,"type":21},200,[24],"1 Recruitment. 2. Collection of written consents for the study. 3. Random assignment to groups with and without intervention. 4. Completion of questionnaires by study participants, postural pattern assessment, temporomandibular joint assessment, and platform assessment.\n\n5\\. Performance of visceral therapy in the group with intervention, in the group without intervention placebo. Duration 5 weeks, treatment 1x per week at the same time of day and given day e.g. Mondays only.\n\n6\\. Reassessment as in step 4. 7. Data collection, statistical analyses. 8. Interpretation of results for female participants. 9. Preparation of results for scientific publications.",[262,263],"Prolapse; Female","Endometriosis-related Pain",[265,266,267,268,269,270],"quaity of life","women","prolapse; female","endometriosis-related pain","visceral therapy","temporomandibular joint",{"date":272,"type":41},"2025-02-07",{"date":274,"type":41},"2023-11-14",{"date":276,"type":21},"2026-09-01",{"name":47,"class":48},{"id":279,"slug":280,"hasResults":11,"nctId":281,"briefTitle":282,"officialTitle":283,"acronym":4,"eligibilityCriteria":284,"healthyVolunteers":57,"sex":91,"minAge":285,"maxAge":286,"enrollmentInfo":287,"targetDuration":4,"studyType":22,"phases":288,"briefSummary":289,"conditions":290,"keywords":292,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":296,"lastUpdatePostDateStruct":297,"startDateStruct":299,"completionDateStruct":301,"leadSponsor":303,"locationsCount":49},"100560780","physiotherapy-management-in-women-with-urinary-incontinence-100560780","NCT06581601","Physiotherapy Management in Women With Urinary Incontinence","Physiotherapy Management in Women With Urinary Incontinence Considering Postural Stability, Postural Pattern, Pelvic Type, Quality of Life, and Sexual Aspect","Inclusion Criteria:\n\n* Urinary incontinence\n* Regular menstrual cycles\n* Pre and post-menopausal period\n* Natural childbirth or cesarean section\n* Deliveries using forceps and vacuum extractors\n\nExclusion Criteria:\n\n* No urinary incontinence\n* Irregular menstrual cycles\n* No childbirth\n* Abdominal surgeries\u002Fprocedures Active cancer No gynecological check-up in the last 12 months Recurrent urogenital infections Joint hypermobility\n\nContorl group will be healthy women","20 Years","80 Years",{"count":226,"type":21},[24],"Main objective:\n\nThe primary aim of the study is to assess whether the author's exercise programme has an effect on reducing urinary incontinence and pelvic floor dysfunction after childbirth, considering vacuum extractor, forceps and caesarean section deliveries.\n\nSecondary objective:\n\nThe secondary objective is to determine whether the duration of the author's exercise programme is sufficient to achieve positive changes in women.",[291],"Urinary Incontinence",[293,294,295],"the author's exercise program","urinary incontinence","physiotherapy","2024-11-05",{"date":298,"type":41},"2024-11-07",{"date":300,"type":41},"2024-08-21",{"date":302,"type":21},"2027-11-20",{"name":47,"class":48},{"id":305,"slug":306,"hasResults":11,"nctId":307,"briefTitle":308,"officialTitle":309,"acronym":310,"eligibilityCriteria":311,"healthyVolunteers":57,"sex":91,"minAge":312,"maxAge":4,"enrollmentInfo":313,"targetDuration":4,"studyType":22,"phases":314,"briefSummary":315,"conditions":316,"keywords":319,"overallStatus":37,"whyStopped":4,"lastUpdateSubmitDate":322,"lastUpdatePostDateStruct":323,"startDateStruct":325,"completionDateStruct":327,"leadSponsor":329,"locationsCount":49},"100562715","physical-activity-guarantees-bone-density-100562715","NCT06606769","Physical Activity Guarantees Bone Density.","Fizyczne Aktywnosci Gwarantem Zdrowych Kosci","BONES","Inclusion Criteria:\n\nwomen\n\nExclusion Criteria:\n\ndiagnosed osteoporosis","50 Years",{"count":226,"type":21},[24],"Bone tissue is crucial for overall health and quality of life, but it undergoes constant internal remodeling, leading to osteoporosis, a widespread bone disease. Regular physical activity can improve bone mineral density (BMD) and prevent osteoporosis. Studies have shown that premenopausal women with regular physical activity have greater BMD. Diagnosing bone resorption is essential, and dual-energy X-ray absorptiometry tests (DXA) and circulating microRNAs (miRNAs) may offer more prognostic potential than conventional markers. The gut microbiome may also regulate bone metabolism, with metabolites like trimethylamine N-oxide (TMAO) playing a role. A project aims to promote systematic physical activity to improve BMD and well-being, support societal mobilization, and conduct preventive examinations for osteoporosis risk. Implementing systematic prevention is important not only for health but also for reducing social and financial costs associated with osteoporosis and associated fractures.",[317,318],"Osteoporosis","Osteopenia",[320,321],"physical activity","bone mineral density","2024-10-08",{"date":324,"type":41},"2024-10-10",{"date":326,"type":41},"2024-09-13",{"date":328,"type":21},"2027-06-30",{"name":47,"class":48},{"id":331,"slug":332,"hasResults":11,"nctId":333,"briefTitle":334,"officialTitle":335,"acronym":4,"eligibilityCriteria":336,"healthyVolunteers":11,"sex":16,"minAge":17,"maxAge":195,"enrollmentInfo":337,"targetDuration":4,"studyType":63,"phases":4,"briefSummary":338,"conditions":339,"keywords":343,"overallStatus":75,"whyStopped":4,"lastUpdateSubmitDate":347,"lastUpdatePostDateStruct":348,"startDateStruct":350,"completionDateStruct":352,"leadSponsor":354,"locationsCount":49},"100550875","relative-energy-deficiency-in-rowers-100550875","NCT06452758","Relative Energy Deficiency in Rowers","Relative Energy Deficiency in Females and Males Rowers - Observational Study","Inclusion Criteria:\n\n* Membership in Polish Rowing Team,\n* minimum five years of training,\n* total training time minimum of 240 minutes,\n* filling out a food diary,\n* finishing 2000-meter ergometer test.\n\nExclusion Criteria:\n\n* Probiotics within the last three months,\n* prebiotics within the last three months\n* antibiotic therapy within the last three months,\n* dietary regime,\n* gastrointestinal diseases.",{"count":61,"type":21},"This study aims to learn about relative energy deficiency in male and female rowers at the end of the direct sport preparation phase of the annual training cycle. The main questions:\n\n\\- How will energy intake influence leptin, cortisol levels, mood, gut discomfort, and permeability? The observational study involves male and female rowers from the Polish rowing team.\n\nParticipants will perform 2000 meter ergometer test and 6000 ergometer test in annual training cycle. Researchers will compare outcomes from both tests.",[340,341,342],"Endothelial Dysfunction","Mood Disorders","Malnutrition, Calorie",[344,345,346],"relative energy deficiency","gut permeability","rowers","2024-06-11",{"date":349,"type":41},"2024-06-13",{"date":351,"type":21},"2024-06-20",{"date":353,"type":21},"2024-06-30",{"name":47,"class":48},""]